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The map label for this gene is nrnA [H]

Identifier: 197294187

GI number: 197294187

Start: 25686

End: 26666

Strand: Reverse

Name: nrnA [H]

Synonym: PAa_0021

Alternate gene names: 197294187

Gene position: 26666-25686 (Counterclockwise)

Preceding gene: 197294188

Following gene: 197294186

Centisome position: 3.03

GC content: 29.77

Gene sequence:

>981_bases
ATGCAAATTATTTATGAACAAATTAAAAAATTTGATAAAATTATTATCCATGGACATATTAATCCTGATGGTGATTGTTA
TGGTGCTCAATTAGGACTCAAAGATGTCATCAAAGCTACTTTTCCTGATAAAAAGGTTTATGCTGTTGGTGAAAACAACC
TTTATTTATCTTTTGTTGGAAGTATGGATCAAATTGAAGATGATTTATTTCAAAATGCTTTAGCTATTATAGTTGATTGT
GGTGAAGAAAAAAGAATTAGTGACAACCGTTTTAAATTAGCTCAAAAAATTATCCGAATCGATCATCATTTATTAACAGA
TCATTATGGCGATTATCAATGGGTTGATTCTAGTTATTCTTCTTGTTCTCAAATGATTTTTGATTTAAAAGAAAATTTTA
AAATGAAATTAACTTATCAAGGTGCTTTGGCGATGTATGTAGGTATTGTTGCTGATACTGGTAATTTTTGTTTTGATCGA
GTTAATCAATATACTTTGAAAGCTGCTTCTTCTCTGTTGGCTTTTGATTTAGATGTTGCAAAAATTTTTTATCACCTTAA
CAAAGAAAATTTAGTTTTGTTTCATTATAAGGCCTATATTTTTCAAAACGCTATTGCTTCTAAAGGTTTTGTTTATCTTG
TCGTTTCTCAAGCGATTTTGAAAAAACTTAATTTAAATTTAGATGTTGCTGCAAGTTTAGTTAATAATTTAGGTCATTTA
GAAAATCATCCAGTGTGGGCTTTTTTTATGGAAAAAGAAGATGGAACTTTTAAAGTGAGTATTCGTTCTCGTGGACCGGA
AATTAATCACATTGCTCAACAATTTAAAGGGGGGGGTCATAGAAGAGCTTGTGGTGCTACTTTGGATTCAAAAGATCAAA
TCCCCGTTTTTGTGGAAAAAATCCAAAAAGCCATTATGACTTTTGAAGCACAACAAAAAAACCACGATAAAAAAGAGCTT
TGTTTTAAATCAAAGCCTTAA

Upstream 100 bases:

>100_bases
TTTATTAAAAGAAAATGATCAAGAAAAAATTGCTCAATTATTTGAAATAGCGCAAAAAAAAGCACTTGCTTAAATAAATA
AAATCATAGAAGGATAAAAT

Downstream 100 bases:

>100_bases
ATTTATTTTTGCCTTTTTAAAATGTAAGAAAGGTTATGGAAAACAACCAAAAAACTCCAAAAAAAAAAAAAAATGAAATA
TCTCAATTAGAATTAAAACC

Product: Phosphoesterase family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQIIYEQIKKFDKIIIHGHINPDGDCYGAQLGLKDVIKATFPDKKVYAVGENNLYLSFVGSMDQIEDDLFQNALAIIVDC
GEEKRISDNRFKLAQKIIRIDHHLLTDHYGDYQWVDSSYSSCSQMIFDLKENFKMKLTYQGALAMYVGIVADTGNFCFDR
VNQYTLKAASSLLAFDLDVAKIFYHLNKENLVLFHYKAYIFQNAIASKGFVYLVVSQAILKKLNLNLDVAASLVNNLGHL
ENHPVWAFFMEKEDGTFKVSIRSRGPEINHIAQQFKGGGHRRACGATLDSKDQIPVFVEKIQKAIMTFEAQQKNHDKKEL
CFKSKP

Sequences:

>Translated_326_residues
MQIIYEQIKKFDKIIIHGHINPDGDCYGAQLGLKDVIKATFPDKKVYAVGENNLYLSFVGSMDQIEDDLFQNALAIIVDC
GEEKRISDNRFKLAQKIIRIDHHLLTDHYGDYQWVDSSYSSCSQMIFDLKENFKMKLTYQGALAMYVGIVADTGNFCFDR
VNQYTLKAASSLLAFDLDVAKIFYHLNKENLVLFHYKAYIFQNAIASKGFVYLVVSQAILKKLNLNLDVAASLVNNLGHL
ENHPVWAFFMEKEDGTFKVSIRSRGPEINHIAQQFKGGGHRRACGATLDSKDQIPVFVEKIQKAIMTFEAQQKNHDKKEL
CFKSKP
>Mature_326_residues
MQIIYEQIKKFDKIIIHGHINPDGDCYGAQLGLKDVIKATFPDKKVYAVGENNLYLSFVGSMDQIEDDLFQNALAIIVDC
GEEKRISDNRFKLAQKIIRIDHHLLTDHYGDYQWVDSSYSSCSQMIFDLKENFKMKLTYQGALAMYVGIVADTGNFCFDR
VNQYTLKAASSLLAFDLDVAKIFYHLNKENLVLFHYKAYIFQNAIASKGFVYLVVSQAILKKLNLNLDVAASLVNNLGHL
ENHPVWAFFMEKEDGTFKVSIRSRGPEINHIAQQFKGGGHRRACGATLDSKDQIPVFVEKIQKAIMTFEAQQKNHDKKEL
CFKSKP

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 37154; Mature: 37154

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIYEQIKKFDKIIIHGHINPDGDCYGAQLGLKDVIKATFPDKKVYAVGENNLYLSFVG
CCHHHHHHHHHCEEEEEECCCCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCEEEEECC
SMDQIEDDLFQNALAIIVDCGEEKRISDNRFKLAQKIIRIDHHLLTDHYGDYQWVDSSYS
CHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHH
SCSQMIFDLKENFKMKLTYQGALAMYVGIVADTGNFCFDRVNQYTLKAASSLLAFDLDVA
HHHHHHHHHHCCCEEEEEECCCEEEHEEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIFYHLNKENLVLFHYKAYIFQNAIASKGFVYLVVSQAILKKLNLNLDVAASLVNNLGHL
HHHHHCCCCCEEEEEHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCC
ENHPVWAFFMEKEDGTFKVSIRSRGPEINHIAQQFKGGGHRRACGATLDSKDQIPVFVEK
CCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
IQKAIMTFEAQQKNHDKKELCFKSKP
HHHHHHHHHHHHCCCCHHHHCCCCCC
>Mature Secondary Structure
MQIIYEQIKKFDKIIIHGHINPDGDCYGAQLGLKDVIKATFPDKKVYAVGENNLYLSFVG
CCHHHHHHHHHCEEEEEECCCCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCEEEEECC
SMDQIEDDLFQNALAIIVDCGEEKRISDNRFKLAQKIIRIDHHLLTDHYGDYQWVDSSYS
CHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHH
SCSQMIFDLKENFKMKLTYQGALAMYVGIVADTGNFCFDRVNQYTLKAASSLLAFDLDVA
HHHHHHHHHHCCCEEEEEECCCEEEHEEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIFYHLNKENLVLFHYKAYIFQNAIASKGFVYLVVSQAILKKLNLNLDVAASLVNNLGHL
HHHHHCCCCCEEEEEHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCC
ENHPVWAFFMEKEDGTFKVSIRSRGPEINHIAQQFKGGGHRRACGATLDSKDQIPVFVEK
CCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
IQKAIMTFEAQQKNHDKKELCFKSKP
HHHHHHHHHHHHCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]