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The map label for this gene is intR [H]

Identifier: 197119440

GI number: 197119440

Start: 3554429

End: 3555739

Strand: Direct

Name: intR [H]

Synonym: Gbem_3069

Alternate gene names: 197119440

Gene position: 3554429-3555739 (Clockwise)

Preceding gene: 197119439

Following gene: 308535346

Centisome position: 77.02

GC content: 51.87

Gene sequence:

>1311_bases
ATGAGAATGAAGAAAGGCAATCTGGCCATCGAGACACCAGCCAAGGAAACCGGAGCCATCAAGAGGCGTAAAGGCTCTAA
AAAGCTCTACGTCGATTTCTACTACTTCGGCCACCGGATCACCCGATCAACGGAACTTGACGACACCCCAGCCAATGAAA
GGAAGGTTCGCGCCTTCCTCAACAGGATCACGGAGCGGATCGAGAACGGAACCTTCAAATTTGCCGAAGCGTTCCCCGGC
TCCTCAGATCAGGAAAAGGCATATTTCACCCAAAAGGAAGGCAGGGAGTACCGACCTGAACCGCATCAGGTGTTATTCGG
CGACTACGCCAAAGAGTGGATGCTGACCATTTACCCCACTTTCGGCTCACCGACCAAGCGGAACGATTACAAGGAAGCTC
TTGAATCGCGTATCCTGCCCCACTTCAAGAACTTCACCTTTTACCAGCTCACCAGCATGGAGCTTTTCAAATTCACTGAG
TCGCTGGTAAGGCAAAAAGGGAAGGACAAAGGGAAGCCGCTTTCAACGGCTCGAAAGGTTAATCTGCTGATACCCTTCCG
GGCCATCTGGAACGATGCCTGCGATCATTACCGCTGGGTACTGAAAAGCCCCTTCGACAACCTGAAAAAGAAGCTGCCGA
AGACTGAGAAGAAAGAGCACACCGTCATAAGGCTTCATGACTGGCTCAAGTTCCTTGATAACCTTGAAGACCATTACCGA
CCCATTGCGGAAATGATGATCCTTACCGGGATGATCCCTTCCGAGCTGGGAGGCCTGAAGCGGGAAGACATTGAAGGAGA
CTACATCAACGTCAGAAGCTCCTATGTCCTCGGGGAAGAAAAGAAGAGCCTCAAGACCGCTTTTAGGAAGAGGCAAATCT
TCATCACCCAAGCCATCAGGGAACGGCTACAGATCATCCTTGACCGTTCCTCTTCCCCCTACGTCTTCATCATGGAGGAC
GGGAAGAGATTCAACAGCAGCCGCTTCAGCAAACTCTGGCAGAAGGCCGTATTAACGGCGGGAATACCGTATGTCACATC
CTACTCTGCCCGTCACTCCTTCGCTGCCTGGAGCCTCATTATCGGCGTTAATCCGCTGAGGCTGGTAAACCTGATGGGAC
ATGCCAGCAAACAGATGGTCTATGAGGTGTACGGGAATTACGTTGAAGGCCTGGAGGACGACGCGGAGGAAATGCTTGAT
TACTTCGGGCGCGACTTCGTGCTACCCCGGAAAAAGAAATCCCCGGTTCCGTTTAGGGACAGTACCGGGGACAGTCTTGG
AAGTTCCGTTCTAACTACTGGAACCATTTAG

Upstream 100 bases:

>100_bases
CGGCTATCAACCTTGACTATTGATTATGAAATGAAATGCCGCTATTCTCCGCACCGGACTTAGACACACTGAAGGGAGGG
TAACGACATGAGGACATAAC

Downstream 100 bases:

>100_bases
TATTATTTGGAGCGGGAAACGGGATTCGAACCCGCGACTTCAACCTTGGCAAGGTTGCACTCTACCACTGAGTTATTCCC
GCTCAATGGAGATCCTGTTT

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRMKKGNLAIETPAKETGAIKRRKGSKKLYVDFYYFGHRITRSTELDDTPANERKVRAFLNRITERIENGTFKFAEAFPG
SSDQEKAYFTQKEGREYRPEPHQVLFGDYAKEWMLTIYPTFGSPTKRNDYKEALESRILPHFKNFTFYQLTSMELFKFTE
SLVRQKGKDKGKPLSTARKVNLLIPFRAIWNDACDHYRWVLKSPFDNLKKKLPKTEKKEHTVIRLHDWLKFLDNLEDHYR
PIAEMMILTGMIPSELGGLKREDIEGDYINVRSSYVLGEEKKSLKTAFRKRQIFITQAIRERLQIILDRSSSPYVFIMED
GKRFNSSRFSKLWQKAVLTAGIPYVTSYSARHSFAAWSLIIGVNPLRLVNLMGHASKQMVYEVYGNYVEGLEDDAEEMLD
YFGRDFVLPRKKKSPVPFRDSTGDSLGSSVLTTGTI

Sequences:

>Translated_436_residues
MRMKKGNLAIETPAKETGAIKRRKGSKKLYVDFYYFGHRITRSTELDDTPANERKVRAFLNRITERIENGTFKFAEAFPG
SSDQEKAYFTQKEGREYRPEPHQVLFGDYAKEWMLTIYPTFGSPTKRNDYKEALESRILPHFKNFTFYQLTSMELFKFTE
SLVRQKGKDKGKPLSTARKVNLLIPFRAIWNDACDHYRWVLKSPFDNLKKKLPKTEKKEHTVIRLHDWLKFLDNLEDHYR
PIAEMMILTGMIPSELGGLKREDIEGDYINVRSSYVLGEEKKSLKTAFRKRQIFITQAIRERLQIILDRSSSPYVFIMED
GKRFNSSRFSKLWQKAVLTAGIPYVTSYSARHSFAAWSLIIGVNPLRLVNLMGHASKQMVYEVYGNYVEGLEDDAEEMLD
YFGRDFVLPRKKKSPVPFRDSTGDSLGSSVLTTGTI
>Mature_436_residues
MRMKKGNLAIETPAKETGAIKRRKGSKKLYVDFYYFGHRITRSTELDDTPANERKVRAFLNRITERIENGTFKFAEAFPG
SSDQEKAYFTQKEGREYRPEPHQVLFGDYAKEWMLTIYPTFGSPTKRNDYKEALESRILPHFKNFTFYQLTSMELFKFTE
SLVRQKGKDKGKPLSTARKVNLLIPFRAIWNDACDHYRWVLKSPFDNLKKKLPKTEKKEHTVIRLHDWLKFLDNLEDHYR
PIAEMMILTGMIPSELGGLKREDIEGDYINVRSSYVLGEEKKSLKTAFRKRQIFITQAIRERLQIILDRSSSPYVFIMED
GKRFNSSRFSKLWQKAVLTAGIPYVTSYSARHSFAAWSLIIGVNPLRLVNLMGHASKQMVYEVYGNYVEGLEDDAEEMLD
YFGRDFVLPRKKKSPVPFRDSTGDSLGSSVLTTGTI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1787607, Length=182, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR022000
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF12167 DUF3596; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 50714; Mature: 50714

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMKKGNLAIETPAKETGAIKRRKGSKKLYVDFYYFGHRITRSTELDDTPANERKVRAFL
CCCCCCCEEEECCCHHHCCHHHCCCCCEEEEEEEEECCEEECCCCCCCCCCCHHHHHHHH
NRITERIENGTFKFAEAFPGSSDQEKAYFTQKEGREYRPEPHQVLFGDYAKEWMLTIYPT
HHHHHHHCCCCEEEHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECHHCCCEEEEEEEC
FGSPTKRNDYKEALESRILPHFKNFTFYQLTSMELFKFTESLVRQKGKDKGKPLSTARKV
CCCCCCCCHHHHHHHHHCCHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHEE
NLLIPFRAIWNDACDHYRWVLKSPFDNLKKKLPKTEKKEHTVIRLHDWLKFLDNLEDHYR
EEEECHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
PIAEMMILTGMIPSELGGLKREDIEGDYINVRSSYVLGEEKKSLKTAFRKRQIFITQAIR
HHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHH
ERLQIILDRSSSPYVFIMEDGKRFNSSRFSKLWQKAVLTAGIPYVTSYSARHSFAAWSLI
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHH
IGVNPLRLVNLMGHASKQMVYEVYGNYVEGLEDDAEEMLDYFGRDFVLPRKKKSPVPFRD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STGDSLGSSVLTTGTI
CCCCHHCCCCCCCCCC
>Mature Secondary Structure
MRMKKGNLAIETPAKETGAIKRRKGSKKLYVDFYYFGHRITRSTELDDTPANERKVRAFL
CCCCCCCEEEECCCHHHCCHHHCCCCCEEEEEEEEECCEEECCCCCCCCCCCHHHHHHHH
NRITERIENGTFKFAEAFPGSSDQEKAYFTQKEGREYRPEPHQVLFGDYAKEWMLTIYPT
HHHHHHHCCCCEEEHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECHHCCCEEEEEEEC
FGSPTKRNDYKEALESRILPHFKNFTFYQLTSMELFKFTESLVRQKGKDKGKPLSTARKV
CCCCCCCCHHHHHHHHHCCHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHEE
NLLIPFRAIWNDACDHYRWVLKSPFDNLKKKLPKTEKKEHTVIRLHDWLKFLDNLEDHYR
EEEECHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
PIAEMMILTGMIPSELGGLKREDIEGDYINVRSSYVLGEEKKSLKTAFRKRQIFITQAIR
HHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHH
ERLQIILDRSSSPYVFIMEDGKRFNSSRFSKLWQKAVLTAGIPYVTSYSARHSFAAWSLI
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHH
IGVNPLRLVNLMGHASKQMVYEVYGNYVEGLEDDAEEMLDYFGRDFVLPRKKKSPVPFRD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STGDSLGSSVLTTGTI
CCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]