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The map label for this gene is ato-2 [H]

Identifier: 197119216

GI number: 197119216

Start: 3272064

End: 3273623

Strand: Reverse

Name: ato-2 [H]

Synonym: Gbem_2843

Alternate gene names: 197119216

Gene position: 3273623-3272064 (Counterclockwise)

Preceding gene: 197119218

Following gene: 197119215

Centisome position: 70.93

GC content: 61.86

Gene sequence:

>1560_bases
ATGAGCGAGCTGCAGCAGAGGATCAGGAAGAAGAGTCTGCACCAAAGGATCATGAGCGCCGAGGATACCATCCCGTTCTT
CAAAAACGGCATGGACCTTGGGTGGTCAGGGTTCACGCCGGTCGGCTATCCCAAGGTGGTGCCCGAGGCGCTGGCGGACT
ACGTAGAGAAAAACAACCTGCAGGGGAAGATGCGGTTCAACCTCTTCATCGGCGCCTCCATCGGCGCCGAGATCGAGGAC
CGCTGGGCATCGCTCTCCATGACCGACAAACGCTGGCCCTACCAGACCGGGAATGTGGTGCAAAAGCAGGTGAATAACGG
CGGCGTGCGCATGGGAGACAAGCACCTCTCGCTCTACGCCCAGGATCTCGCCTACGGCTTCTACACCAAGGAAAGGGGAG
GGGGGTTCGATCTCGGGCTCATCGAGGCAAGCGGCATCACTGAAGACGGCTCCATCATCCTCGGCGGCTCCATCGGCTGC
GCTACCGAGGTGATCCAGCACTCGGACCGGCTCATCATCGAGATCAACACGGCGATCCCCTCCTTCGAAGGGCTCCACGA
CATCGTTATGACCGAGCGCCCTCCCTACAAGAAACCGTACCTGATCAGCCGCGTAGACGACCGGATCGGCTCACCTTACG
TCCCGTGCGATCCGGACAAGATCATCGCCATCGTGGAATCCAAAAAGCCCGACCGGGGGCGCGCCCTGAGCGCTCCCGAC
GCCGTGTCGGAGCAGATCGCGGCGCATATCATCGACTTCTTCCAGTTCGAGGTGAAGGCGGGGCGCCTGCCGAAAAACCT
GCTCCCGCTGCAGTCGGGGGTCGGCAACATAGCCAACGCGGTGGTGGGGGGGCTGGTGCAGGGACCGTTCAGCAACGTCC
AGGTCTGGACCGAGGTGATCCAGGACACCATGCTGGACTTCTTCGACTCCGGCAAGCTCGACTTCGCCTCCTCAACCTCG
CTCTCGCTCTCCGAGGGGGGCTTCCAGCGCCTCTACGACAACTGGGATTTCTACACCGGAAAAGTGGTGCTGCGCCCCAT
GCAGATCAGCAACAACCCCGAGCCGATCCGCCGCCTGGGGGTCATCGCCATGAACACCCCGGTGGAATTCGACATCTACG
GCCACGCCAACTCGACACTGGTCGGGGGCACCAGGATGATCAACGGTATCGGCGGCTCCGGGGACTTCCTGAGAAACGCC
TACCTCTCCATCATGCACACCCCCTCCACCCGGCCGTCGAAGACCGACGCAAACGGCATTACCTGCGTGGTCCCCATGGT
CCCCCACGTCGACCATACCGAGCACGACCTCGACGTGCTGGTGACCGAGCAGGGACTCGCCGACCTGCGCGGACTCTGCC
CGAGAGAGCGGGCTCAGCAGATCATCTCCAAATGCGTACACCCCGAGTACAAGCCGATCATGCAGGAATACTACGAGCGG
GCGCAGCGGGAGTGCTTCGAGCAAAACGTCGGGCACGAGCCCCACATGCTCTTCAAGGTCTTCAAGATGCAGCAGAGCCT
GGCGGAAAAGGGGACCATGAAGATCCCCAACTGGGACTAG

Upstream 100 bases:

>100_bases
TTCCTTAGCCGCCGCCACTGTTGCCCGATTGGAGTTGCCCCTTGGAACATGAACGGCCCGGGGCATGACTTATGGCAGGG
ATATCAAAACGGAGGTTTAA

Downstream 100 bases:

>100_bases
GTACTAGCGGGGGGAAACCATGAAAAAAAAGCGGGCCAAAGAGGGAAACCCGCCGCAGCGGATGGAAAAGGCCGTGGAGC
TTCTGGAGGCGCTCGCCATC

Product: succinyl:acetate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MSELQQRIRKKSLHQRIMSAEDTIPFFKNGMDLGWSGFTPVGYPKVVPEALADYVEKNNLQGKMRFNLFIGASIGAEIED
RWASLSMTDKRWPYQTGNVVQKQVNNGGVRMGDKHLSLYAQDLAYGFYTKERGGGFDLGLIEASGITEDGSIILGGSIGC
ATEVIQHSDRLIIEINTAIPSFEGLHDIVMTERPPYKKPYLISRVDDRIGSPYVPCDPDKIIAIVESKKPDRGRALSAPD
AVSEQIAAHIIDFFQFEVKAGRLPKNLLPLQSGVGNIANAVVGGLVQGPFSNVQVWTEVIQDTMLDFFDSGKLDFASSTS
LSLSEGGFQRLYDNWDFYTGKVVLRPMQISNNPEPIRRLGVIAMNTPVEFDIYGHANSTLVGGTRMINGIGGSGDFLRNA
YLSIMHTPSTRPSKTDANGITCVVPMVPHVDHTEHDLDVLVTEQGLADLRGLCPRERAQQIISKCVHPEYKPIMQEYYER
AQRECFEQNVGHEPHMLFKVFKMQQSLAEKGTMKIPNWD

Sequences:

>Translated_519_residues
MSELQQRIRKKSLHQRIMSAEDTIPFFKNGMDLGWSGFTPVGYPKVVPEALADYVEKNNLQGKMRFNLFIGASIGAEIED
RWASLSMTDKRWPYQTGNVVQKQVNNGGVRMGDKHLSLYAQDLAYGFYTKERGGGFDLGLIEASGITEDGSIILGGSIGC
ATEVIQHSDRLIIEINTAIPSFEGLHDIVMTERPPYKKPYLISRVDDRIGSPYVPCDPDKIIAIVESKKPDRGRALSAPD
AVSEQIAAHIIDFFQFEVKAGRLPKNLLPLQSGVGNIANAVVGGLVQGPFSNVQVWTEVIQDTMLDFFDSGKLDFASSTS
LSLSEGGFQRLYDNWDFYTGKVVLRPMQISNNPEPIRRLGVIAMNTPVEFDIYGHANSTLVGGTRMINGIGGSGDFLRNA
YLSIMHTPSTRPSKTDANGITCVVPMVPHVDHTEHDLDVLVTEQGLADLRGLCPRERAQQIISKCVHPEYKPIMQEYYER
AQRECFEQNVGHEPHMLFKVFKMQQSLAEKGTMKIPNWD
>Mature_518_residues
SELQQRIRKKSLHQRIMSAEDTIPFFKNGMDLGWSGFTPVGYPKVVPEALADYVEKNNLQGKMRFNLFIGASIGAEIEDR
WASLSMTDKRWPYQTGNVVQKQVNNGGVRMGDKHLSLYAQDLAYGFYTKERGGGFDLGLIEASGITEDGSIILGGSIGCA
TEVIQHSDRLIIEINTAIPSFEGLHDIVMTERPPYKKPYLISRVDDRIGSPYVPCDPDKIIAIVESKKPDRGRALSAPDA
VSEQIAAHIIDFFQFEVKAGRLPKNLLPLQSGVGNIANAVVGGLVQGPFSNVQVWTEVIQDTMLDFFDSGKLDFASSTSL
SLSEGGFQRLYDNWDFYTGKVVLRPMQISNNPEPIRRLGVIAMNTPVEFDIYGHANSTLVGGTRMINGIGGSGDFLRNAY
LSIMHTPSTRPSKTDANGITCVVPMVPHVDHTEHDLDVLVTEQGLADLRGLCPRERAQQIISKCVHPEYKPIMQEYYERA
QRECFEQNVGHEPHMLFKVFKMQQSLAEKGTMKIPNWD

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=499, Percent_Identity=41.8837675350701, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6319456, Length=518, Percent_Identity=56.7567567567568, Blast_Score=622, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 57774; Mature: 57642

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELQQRIRKKSLHQRIMSAEDTIPFFKNGMDLGWSGFTPVGYPKVVPEALADYVEKNNL
CHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
QGKMRFNLFIGASIGAEIEDRWASLSMTDKRWPYQTGNVVQKQVNNGGVRMGDKHLSLYA
CEEEEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEECCHHHHHHH
QDLAYGFYTKERGGGFDLGLIEASGITEDGSIILGGSIGCATEVIQHSDRLIIEINTAIP
HHHHHHEEECCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCC
SFEGLHDIVMTERPPYKKPYLISRVDDRIGSPYVPCDPDKIIAIVESKKPDRGRALSAPD
CCCCHHHHHCCCCCCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCH
AVSEQIAAHIIDFFQFEVKAGRLPKNLLPLQSGVGNIANAVVGGLVQGPFSNVQVWTEVI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHH
QDTMLDFFDSGKLDFASSTSLSLSEGGFQRLYDNWDFYTGKVVLRPMQISNNPEPIRRLG
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEECEEEEEEEECCCCCHHHHHHC
VIAMNTPVEFDIYGHANSTLVGGTRMINGIGGSGDFLRNAYLSIMHTPSTRPSKTDANGI
EEEECCCEEEEEECCCCCEEECCHHEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCCCC
TCVVPMVPHVDHTEHDLDVLVTEQGLADLRGLCPRERAQQIISKCVHPEYKPIMQEYYER
EEEEECCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AQRECFEQNVGHEPHMLFKVFKMQQSLAEKGTMKIPNWD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SELQQRIRKKSLHQRIMSAEDTIPFFKNGMDLGWSGFTPVGYPKVVPEALADYVEKNNL
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
QGKMRFNLFIGASIGAEIEDRWASLSMTDKRWPYQTGNVVQKQVNNGGVRMGDKHLSLYA
CEEEEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEECCHHHHHHH
QDLAYGFYTKERGGGFDLGLIEASGITEDGSIILGGSIGCATEVIQHSDRLIIEINTAIP
HHHHHHEEECCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCC
SFEGLHDIVMTERPPYKKPYLISRVDDRIGSPYVPCDPDKIIAIVESKKPDRGRALSAPD
CCCCHHHHHCCCCCCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCH
AVSEQIAAHIIDFFQFEVKAGRLPKNLLPLQSGVGNIANAVVGGLVQGPFSNVQVWTEVI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHH
QDTMLDFFDSGKLDFASSTSLSLSEGGFQRLYDNWDFYTGKVVLRPMQISNNPEPIRRLG
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEECEEEEEEEECCCCCHHHHHHC
VIAMNTPVEFDIYGHANSTLVGGTRMINGIGGSGDFLRNAYLSIMHTPSTRPSKTDANGI
EEEECCCEEEEEECCCCCEEECCHHEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCCCC
TCVVPMVPHVDHTEHDLDVLVTEQGLADLRGLCPRERAQQIISKCVHPEYKPIMQEYYER
EEEEECCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AQRECFEQNVGHEPHMLFKVFKMQQSLAEKGTMKIPNWD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]