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The map label for this gene is tsf

Identifier: 197119128

GI number: 197119128

Start: 3184613

End: 3185263

Strand: Reverse

Name: tsf

Synonym: Gbem_2755

Alternate gene names: 197119128

Gene position: 3185263-3184613 (Counterclockwise)

Preceding gene: 197119129

Following gene: 197119127

Centisome position: 69.02

GC content: 60.52

Gene sequence:

>651_bases
GTGAGCATTACAGCGGCACAGGTAAACGAACTCAGAAAAGCAACTGGTGCAGGCCTCATGGACTGCAAGAAGGCGCTGAC
CGAAACCGGCGGCGATCACGAGAAGGCGATCGACTACCTCCGTACCAAGGGCCTGGCAGCCGCCTCCAAGAAGGCCGGCC
GTGCGGCAACCGAAGGGCTCGTCGGCTCCTACATCCACGCCGGCGGCAAGATCGGCGTCCTGGTGGAAGTCAACTGCGAG
ACCGACTTCGTCGCCAAGAACGAGAACTTCCAGGGCTTCGTGAAGGACATCGCGATGCACATCGCTGCAGCATCCCCGCT
CTACGTTCGCCGTGAAGAAGTGCCGGCTGAACTGATCGAGCGCGAGAAGGCGATCTACCGCGAGAAGGCAAAGGAAAGCG
GCAAGCCGGCAGCCATCATCGAGAAGATCCTCGACGGCCAGATCAACAAGTTCTTCGCAGACATCTGCCTCCTCGAGCAG
ACCTACGTGAAGGACCCGGACAAGACCATCCAGACCTTCCTCAACGAGACCATCGCCTCCATCGGCGAGAACATGAGCAT
CCGCCGCTTCGCCAAGTTCGTCCTGGGCGAAGGGCTTGCCAAGAAAGAAAGCGACTTCGCGGCTGAGGTCGCTGCGGCGG
TCGGCCAGTAA

Upstream 100 bases:

>100_bases
CTTAATCAGCTCCGCCCCTTCCTGCCGAAACTGCAGTACCGATCGATAACAACATCTATGAAGCCCGCGTCCTTGGGCGC
GGGCGACTGTGGAGGATAAC

Downstream 100 bases:

>100_bases
GACGTCCCAAAAGAGCCGGCCATGAACCATGGGCGGCTCTTTTTCTATCTGCAGCAAGGCCGGTGCCCCGGCACCGTCCG
TTTTTCCCCGCTGATCAAGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRTKGLAAASKKAGRAATEGLVGSYIHAGGKIGVLVEVNCE
TDFVAKNENFQGFVKDIAMHIAAASPLYVRREEVPAELIEREKAIYREKAKESGKPAAIIEKILDGQINKFFADICLLEQ
TYVKDPDKTIQTFLNETIASIGENMSIRRFAKFVLGEGLAKKESDFAAEVAAAVGQ

Sequences:

>Translated_216_residues
MSITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRTKGLAAASKKAGRAATEGLVGSYIHAGGKIGVLVEVNCE
TDFVAKNENFQGFVKDIAMHIAAASPLYVRREEVPAELIEREKAIYREKAKESGKPAAIIEKILDGQINKFFADICLLEQ
TYVKDPDKTIQTFLNETIASIGENMSIRRFAKFVLGEGLAKKESDFAAEVAAAVGQ
>Mature_215_residues
SITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRTKGLAAASKKAGRAATEGLVGSYIHAGGKIGVLVEVNCET
DFVAKNENFQGFVKDIAMHIAAASPLYVRREEVPAELIEREKAIYREKAKESGKPAAIIEKILDGQINKFFADICLLEQT
YVKDPDKTIQTFLNETIASIGENMSIRRFAKFVLGEGLAKKESDFAAEVAAAVGQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084498, Length=94, Percent_Identity=43.6170212765958, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI291084502, Length=94, Percent_Identity=43.6170212765958, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI291084500, Length=186, Percent_Identity=30.1075268817204, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI171846268, Length=94, Percent_Identity=43.6170212765958, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786366, Length=163, Percent_Identity=41.1042944785276, Blast_Score=108, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19921466, Length=96, Percent_Identity=43.75, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_GEOBB (B5EHW0)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002139555.1
- GeneID:   6782753
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_2755
- HOGENOM:   HBG713289
- OMA:   MVELSCE
- ProtClustDB:   PRK12332
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 23340; Mature: 23209

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRTKGLAAASKKAGRAATEGL
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCHHHHHHH
VGSYIHAGGKIGVLVEVNCETDFVAKNENFQGFVKDIAMHIAAASPLYVRREEVPAELIE
HHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHH
REKAIYREKAKESGKPAAIIEKILDGQINKFFADICLLEQTYVKDPDKTIQTFLNETIAS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IGENMSIRRFAKFVLGEGLAKKESDFAAEVAAAVGQ
HCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SITAAQVNELRKATGAGLMDCKKALTETGGDHEKAIDYLRTKGLAAASKKAGRAATEGL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCHHHHHHH
VGSYIHAGGKIGVLVEVNCETDFVAKNENFQGFVKDIAMHIAAASPLYVRREEVPAELIE
HHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHH
REKAIYREKAKESGKPAAIIEKILDGQINKFFADICLLEQTYVKDPDKTIQTFLNETIAS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IGENMSIRRFAKFVLGEGLAKKESDFAAEVAAAVGQ
HCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA