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The map label for this gene is glmM

Identifier: 197119012

GI number: 197119012

Start: 3050476

End: 3051840

Strand: Reverse

Name: glmM

Synonym: Gbem_2635

Alternate gene names: 197119012

Gene position: 3051840-3050476 (Counterclockwise)

Preceding gene: 197119013

Following gene: 197119011

Centisome position: 66.13

GC content: 61.98

Gene sequence:

>1365_bases
ATGAAGAAGCTTTTCGGAACGGACGGGGTGCGCGGTGTGGCCAACGTCTATCCGATGACTGCAGAAATGGCAATGCAGAT
CGGCCGCGCGGCCGCCTACATCTTCAAAAACGGCAAGAAACGCCACCGTATCGTGATCGGCAAGGACACGCGCCTCTCCG
GCTACATGCTTGAAAGCGCGCTCATGGCCGGCATCTGCTCTATGGGCGTGGACGTGCTCCTGGTAGGGCCGCTGCCTACC
CCCGGCATCGCCAACATCACCTCCTCCATGCGCGCCGACGCAGGCGTCGTGATCTCCGCTTCCCACAACCCCTTCGAGGA
CAATGGGATCAAGTTCTTCTCGCGCGACGGCTTCAAGCTTCCCGACGAGACCGAGCTGATGATGGAGGAGCTGATCTTCT
CCAAGCGGATCGATTCCTTGCGCCCGACCGCCAAGGAAGTGGGGAAGGCGTACCGCATCGACGACGCCCAGGGGCGCTTC
GTCGTCTTCCTGAAGAGCACCTTCCCCAAGGATCTAGATCTCTCCGGGCTTAAGATCGTCCTCGACTGCGCCAACGGCGC
CGCCTACAAGGTCGCACCCGCCGTCTTCGAGGAACTGGGCGCGGAGGTCATCTCCATCGGCGTCAAGCCAAACGGCACCA
ACATCAACGCCGACTGCGGATCGCTGCATCCCGAGGTGATGAGCCAGGCGGTGAAGGAACACGGCGCCGACTTGGGCGTT
GCGCTCGACGGCGACGCCGACCGGGTCATTTTCGTGGACGAGTACGGCAACGTGGTCGACGGCGACCGCATCATGGCGAT
CTGCGCGACCGAAATGATCCGGCAAGGGATCCTGAAGCAGAACACGCTGGTGGCGACAGTGATGAGCAACATGGGACTCG
ACATAGCCATGAAACGCGCCGGCGGCCAGGTCATCAAGACCGCGGTCGGGGACCGTTACGTTGTGGAGGAGATGCTCAAG
GGGGGCTACAACCTCGGGGGCGAGCAGTCCGGCCACATGATCTTCCTCGACCACAACACCACCGGCGACGGCGTCCTTTC
GGCGCTGCAGGTGCTCGCCATCATGCAGCGTCACCAAAAGCGTCTATCCGAGCTCGCCCTGGTCATGGAACCGCTGCCGC
AGGTGCTCGTCAACGTCCGCCTGGCTGAGAAATCGGACATCATGCAGGTCCCCGAGATAGCGAAGTTGATCAACGACGTC
GAGGAAAAGCTCAAGGGCGAGGGAAGGGTCCTCATCCGCTACTCCGGCACGGAGCCGCTTTTGCGCATCATGCTGGAAGG
AAGCGACGAGGGGGATATTCGCTGCTGGGCCAACGACATAGCTTCCATCGTGGCACAGAAGCTGGGAGGTGAGGCGCGTG
GCTAG

Upstream 100 bases:

>100_bases
GATGACCTGGGAAAAGTGGGGAGAGCAGCACCCAATTGGTGGCGGAAAACGCTGCCTGATCAGCAGGTAAATAACTAAAA
TTCATCGCATGAGGTGATCT

Downstream 100 bases:

>100_bases
ACTGGGAGTGAACATAGATCACGTGGCGACGCTTCGGCAGGCGAGGGGGGGGACGGAACCGGACCCGGTCGCAGCCGCCG
CCATCGCCGAATTCGCCGGT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKKLFGTDGVRGVANVYPMTAEMAMQIGRAAAYIFKNGKKRHRIVIGKDTRLSGYMLESALMAGICSMGVDVLLVGPLPT
PGIANITSSMRADAGVVISASHNPFEDNGIKFFSRDGFKLPDETELMMEELIFSKRIDSLRPTAKEVGKAYRIDDAQGRF
VVFLKSTFPKDLDLSGLKIVLDCANGAAYKVAPAVFEELGAEVISIGVKPNGTNINADCGSLHPEVMSQAVKEHGADLGV
ALDGDADRVIFVDEYGNVVDGDRIMAICATEMIRQGILKQNTLVATVMSNMGLDIAMKRAGGQVIKTAVGDRYVVEEMLK
GGYNLGGEQSGHMIFLDHNTTGDGVLSALQVLAIMQRHQKRLSELALVMEPLPQVLVNVRLAEKSDIMQVPEIAKLINDV
EEKLKGEGRVLIRYSGTEPLLRIMLEGSDEGDIRCWANDIASIVAQKLGGEARG

Sequences:

>Translated_454_residues
MKKLFGTDGVRGVANVYPMTAEMAMQIGRAAAYIFKNGKKRHRIVIGKDTRLSGYMLESALMAGICSMGVDVLLVGPLPT
PGIANITSSMRADAGVVISASHNPFEDNGIKFFSRDGFKLPDETELMMEELIFSKRIDSLRPTAKEVGKAYRIDDAQGRF
VVFLKSTFPKDLDLSGLKIVLDCANGAAYKVAPAVFEELGAEVISIGVKPNGTNINADCGSLHPEVMSQAVKEHGADLGV
ALDGDADRVIFVDEYGNVVDGDRIMAICATEMIRQGILKQNTLVATVMSNMGLDIAMKRAGGQVIKTAVGDRYVVEEMLK
GGYNLGGEQSGHMIFLDHNTTGDGVLSALQVLAIMQRHQKRLSELALVMEPLPQVLVNVRLAEKSDIMQVPEIAKLINDV
EEKLKGEGRVLIRYSGTEPLLRIMLEGSDEGDIRCWANDIASIVAQKLGGEARG
>Mature_454_residues
MKKLFGTDGVRGVANVYPMTAEMAMQIGRAAAYIFKNGKKRHRIVIGKDTRLSGYMLESALMAGICSMGVDVLLVGPLPT
PGIANITSSMRADAGVVISASHNPFEDNGIKFFSRDGFKLPDETELMMEELIFSKRIDSLRPTAKEVGKAYRIDDAQGRF
VVFLKSTFPKDLDLSGLKIVLDCANGAAYKVAPAVFEELGAEVISIGVKPNGTNINADCGSLHPEVMSQAVKEHGADLGV
ALDGDADRVIFVDEYGNVVDGDRIMAICATEMIRQGILKQNTLVATVMSNMGLDIAMKRAGGQVIKTAVGDRYVVEEMLK
GGYNLGGEQSGHMIFLDHNTTGDGVLSALQVLAIMQRHQKRLSELALVMEPLPQVLVNVRLAEKSDIMQVPEIAKLINDV
EEKLKGEGRVLIRYSGTEPLLRIMLEGSDEGDIRCWANDIASIVAQKLGGEARG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=50.9009009009009, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1788361, Length=445, Percent_Identity=28.7640449438202, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_GEOBB (B5EHA7)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002139439.1
- ProteinModelPortal:   B5EHA7
- SMR:   B5EHA7
- GeneID:   6782632
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_2635
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14314
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49086; Mature: 49086

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFGTDGVRGVANVYPMTAEMAMQIGRAAAYIFKNGKKRHRIVIGKDTRLSGYMLESA
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
LMAGICSMGVDVLLVGPLPTPGIANITSSMRADAGVVISASHNPFEDNGIKFFSRDGFKL
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCC
PDETELMMEELIFSKRIDSLRPTAKEVGKAYRIDDAQGRFVVFLKSTFPKDLDLSGLKIV
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCEEECCCCCCCEEEEEECCCCCCCCCCCCEEE
LDCANGAAYKVAPAVFEELGAEVISIGVKPNGTNINADCGSLHPEVMSQAVKEHGADLGV
EECCCCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
ALDGDADRVIFVDEYGNVVDGDRIMAICATEMIRQGILKQNTLVATVMSNMGLDIAMKRA
EECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEHHC
GGQVIKTAVGDRYVVEEMLKGGYNLGGEQSGHMIFLDHNTTGDGVLSALQVLAIMQRHQK
CCCEEHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
RLSELALVMEPLPQVLVNVRLAEKSDIMQVPEIAKLINDVEEKLKGEGRVLIRYSGTEPL
HHHHHHHHHHHHHHHHHEEHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
LRIMLEGSDEGDIRCWANDIASIVAQKLGGEARG
EHHEECCCCCCCEEEHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKLFGTDGVRGVANVYPMTAEMAMQIGRAAAYIFKNGKKRHRIVIGKDTRLSGYMLESA
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
LMAGICSMGVDVLLVGPLPTPGIANITSSMRADAGVVISASHNPFEDNGIKFFSRDGFKL
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCC
PDETELMMEELIFSKRIDSLRPTAKEVGKAYRIDDAQGRFVVFLKSTFPKDLDLSGLKIV
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCEEECCCCCCCEEEEEECCCCCCCCCCCCEEE
LDCANGAAYKVAPAVFEELGAEVISIGVKPNGTNINADCGSLHPEVMSQAVKEHGADLGV
EECCCCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
ALDGDADRVIFVDEYGNVVDGDRIMAICATEMIRQGILKQNTLVATVMSNMGLDIAMKRA
EECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEHHC
GGQVIKTAVGDRYVVEEMLKGGYNLGGEQSGHMIFLDHNTTGDGVLSALQVLAIMQRHQK
CCCEEHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
RLSELALVMEPLPQVLVNVRLAEKSDIMQVPEIAKLINDVEEKLKGEGRVLIRYSGTEPL
HHHHHHHHHHHHHHHHHEEHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
LRIMLEGSDEGDIRCWANDIASIVAQKLGGEARG
EHHEECCCCCCCEEEHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA