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The map label for this gene is kdpE-2 [H]

Identifier: 197118981

GI number: 197118981

Start: 3018913

End: 3019653

Strand: Reverse

Name: kdpE-2 [H]

Synonym: Gbem_2604

Alternate gene names: 197118981

Gene position: 3019653-3018913 (Counterclockwise)

Preceding gene: 197118982

Following gene: 197118978

Centisome position: 65.43

GC content: 59.65

Gene sequence:

>741_bases
ATGGCTAGTGCAATAAGGACGGAATCCGTTGGAGCGGGTACTGAAAAACAAAGAGGGGAAAACCTTCCGCGCCTGCTCAT
GGTGGATGATGAGTTAGCGGTATTGCGCTTTCTGCGAGCGGCATTGAATACCGGAGAATTCAGGCTGTACGAGGCGCAGA
ATGGACACGCCGCTCTCGCGGCCGCAGCTGCGGTCAGGCCCGACATCATCCTGCAGGACCTGGGTCTTCCCGACATGGAC
GGGGTCGAGGTGATCAAGAGGATCCGGGAGTGGTCCCAGGTTCCCATCATCGTGCTTTCGGTCCGGGACAGCGACGACGA
TAAGGTGGGCGCCCTCGACGCCGGTGCGGACGACTACCTGATCAAGCCCTTCAGCGTCGCAGAGTTGCAGGCCCGCATCC
GTGTTTCGCTCAGAAGGAGCTTGCAGCAAGCGCCCGAGCCGGTGTACCGCTGCAACGAGCTGGAGGTTGACCTGGCGCTG
CGCCGGGTGCTGCTTTCAGGGAAGGAGGTTCAGGTAACACCCACCGAATACGAGCTCCTGCGCCTGCTGGTGACTCATGC
TGGCAGAGTTCTAACGCACAGCCAGATCCTCAAACAGATATGGGGAGTTGCCTACGTAGAGCAGCAAAACGTCCTGCGGG
TCAACATACGTAACCTGCGCCAGAAGATCGAGCCGGATCCATCCCGGCCGTTCTACATCACCACAGAGGTCGGGGTGGGG
TATCGGCTTCGCAGTGAGTAA

Upstream 100 bases:

>100_bases
AAGGGCATTGTGGAGGCGCACGGCGGGACGATTCATGCAGAGAATCGTGAAGGGGGCGGCCTGAAGATAACGGTACAGCT
TCCCGTGGAAGGAGAAGGAC

Downstream 100 bases:

>100_bases
ATGGCTTGAAGTTGTTGGCGGGGGAGAGGTCTGTTGATGAGCGAACCTGGCGGGTGCGTACTGCCGCGCAGCATCCGATA
GCGCTTAGTGCGGCATCCCG

Product: winged-helix transcriptional response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MASAIRTESVGAGTEKQRGENLPRLLMVDDELAVLRFLRAALNTGEFRLYEAQNGHAALAAAAAVRPDIILQDLGLPDMD
GVEVIKRIREWSQVPIIVLSVRDSDDDKVGALDAGADDYLIKPFSVAELQARIRVSLRRSLQQAPEPVYRCNELEVDLAL
RRVLLSGKEVQVTPTEYELLRLLVTHAGRVLTHSQILKQIWGVAYVEQQNVLRVNIRNLRQKIEPDPSRPFYITTEVGVG
YRLRSE

Sequences:

>Translated_246_residues
MASAIRTESVGAGTEKQRGENLPRLLMVDDELAVLRFLRAALNTGEFRLYEAQNGHAALAAAAAVRPDIILQDLGLPDMD
GVEVIKRIREWSQVPIIVLSVRDSDDDKVGALDAGADDYLIKPFSVAELQARIRVSLRRSLQQAPEPVYRCNELEVDLAL
RRVLLSGKEVQVTPTEYELLRLLVTHAGRVLTHSQILKQIWGVAYVEQQNVLRVNIRNLRQKIEPDPSRPFYITTEVGVG
YRLRSE
>Mature_245_residues
ASAIRTESVGAGTEKQRGENLPRLLMVDDELAVLRFLRAALNTGEFRLYEAQNGHAALAAAAAVRPDIILQDLGLPDMDG
VEVIKRIREWSQVPIIVLSVRDSDDDKVGALDAGADDYLIKPFSVAELQARIRVSLRRSLQQAPEPVYRCNELEVDLALR
RVLLSGKEVQVTPTEYELLRLLVTHAGRVLTHSQILKQIWGVAYVEQQNVLRVNIRNLRQKIEPDPSRPFYITTEVGVGY
RLRSE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=49.7757847533632, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.7466063348416, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.9557522123894, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.7272727272727, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=35.2941176470588, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=32.0833333333333, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=31.2217194570136, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=31.9634703196347, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=29.7777777777778, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=26.6375545851528, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=31.390134529148, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=31.3304721030043, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.2576419213974, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787229, Length=214, Percent_Identity=29.9065420560748, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=36.1538461538462, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790299, Length=103, Percent_Identity=33.9805825242718, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=30.7692307692308, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27616; Mature: 27485

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAIRTESVGAGTEKQRGENLPRLLMVDDELAVLRFLRAALNTGEFRLYEAQNGHAALA
CCCCCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
AAAAVRPDIILQDLGLPDMDGVEVIKRIREWSQVPIIVLSVRDSDDDKVGALDAGADDYL
HHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCE
IKPFSVAELQARIRVSLRRSLQQAPEPVYRCNELEVDLALRRVLLSGKEVQVTPTEYELL
ECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCEEEECCHHHHHH
RLLVTHAGRVLTHSQILKQIWGVAYVEQQNVLRVNIRNLRQKIEPDPSRPFYITTEVGVG
HHHHHHCCHHHHHHHHHHHHHCEEEECCCCEEEEEHHHHHHHCCCCCCCCEEEEEECCCC
YRLRSE
EEECCC
>Mature Secondary Structure 
ASAIRTESVGAGTEKQRGENLPRLLMVDDELAVLRFLRAALNTGEFRLYEAQNGHAALA
CCCCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
AAAAVRPDIILQDLGLPDMDGVEVIKRIREWSQVPIIVLSVRDSDDDKVGALDAGADDYL
HHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCE
IKPFSVAELQARIRVSLRRSLQQAPEPVYRCNELEVDLALRRVLLSGKEVQVTPTEYELL
ECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCEEEECCHHHHHH
RLLVTHAGRVLTHSQILKQIWGVAYVEQQNVLRVNIRNLRQKIEPDPSRPFYITTEVGVG
HHHHHHCCHHHHHHHHHHHHHCEEEECCCCEEEEEHHHHHHHCCCCCCCCEEEEEECCCC
YRLRSE
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]