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The map label for this gene is kfoC [H]

Identifier: 197118951

GI number: 197118951

Start: 2983981

End: 2984832

Strand: Reverse

Name: kfoC [H]

Synonym: Gbem_2574

Alternate gene names: 197118951

Gene position: 2984832-2983981 (Counterclockwise)

Preceding gene: 197118952

Following gene: 197118950

Centisome position: 64.67

GC content: 57.51

Gene sequence:

>852_bases
TTGAGCGGTGGAGGCGAGCGCCAGTACAGGCAGGAAGCTTCGTCTGAGGAGTCCTGCTTTTTAAGCATTATCACGCCTGT
TTACAACGGTGCGGACTATATCGAGTTCTGCATACGGAACGTGATAGGCCAAAACTGCCCCGGCATCGAGCACATCATCA
TCGATGGCGGCTCCACCGACAGCACCGCTGAAATCATCAGCAAGTACGCGGCAGTCAATCCACATATCAGGTGGGTGTCG
GAAAAGGACGAGGGGCAGTCGCATGCCATGAACAAAGCGATCGCCATGGCGCGCGGAAGCATCGTTGGTTTTCTGAATGC
GGACGATTACTACGAGCCCGATATCCTCTGCCGCATCGTGGAAATTTTCCAAGGGCTGCCGGCGCCAAGCCTGCTCGTGG
GCAACTGCAACGTCTGGGACAACGAGGGCAGGCTCTGGTTCGTGAGCCGTCCGGCGCAGATCGGCCTGAAGAACCTGCTG
CTGGGGAGGTTCCTGGAGGCCTTCCCGATGAACCCGTCCGCCTATTTCTACCACAAGTCGTTGCACCAGCGGATCGGGAT
GTACGACACTGGCGAGCATTTCGGCATGGACCTGCAGTTCATCTTCCAGGCCGTGCAGAAGGCAAAGGTCACCTACCTGG
ACGAGACCTGGGGAAATTACAGGTATCTGGAAGGGACCAAGACCTATGAGGACGATAAGTCCGGTGGCAACGGGACGAGA
GTGAAACAGATGACCCTGCGCTACCGGCAACAGCAACCCCTTTATTACCGTGTCTACCTGCTGGCCATCGAGGCGTGGAT
CAGGGCCGTGCGCCTGATTCGACGCCCTTTCGCCGCCGAGGATAAGCTTTAG

Upstream 100 bases:

>100_bases
AAAGCAAGGAGTTGATTCGGATTGGCGAGGCCAACCTGGAAAGATTGGGTAACTGCCTGCTCGAAGCCGCGCAGTCCGTT
GTCAGACGGAGGGCCGGGTC

Downstream 100 bases:

>100_bases
ATGGAGCATCTTCCCTTCATATCGATCATCATCCCGACCTACAACCGGTCGCAACTGCTCCCGCTCACGTTGGACAGCTT
CCTTGCACAGGACTACCCCA

Product: family glycosyltransferase

Products: NA

Alternate protein names: CS; Chondroitin polymerase; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSGGGERQYRQEASSEESCFLSIITPVYNGADYIEFCIRNVIGQNCPGIEHIIIDGGSTDSTAEIISKYAAVNPHIRWVS
EKDEGQSHAMNKAIAMARGSIVGFLNADDYYEPDILCRIVEIFQGLPAPSLLVGNCNVWDNEGRLWFVSRPAQIGLKNLL
LGRFLEAFPMNPSAYFYHKSLHQRIGMYDTGEHFGMDLQFIFQAVQKAKVTYLDETWGNYRYLEGTKTYEDDKSGGNGTR
VKQMTLRYRQQQPLYYRVYLLAIEAWIRAVRLIRRPFAAEDKL

Sequences:

>Translated_283_residues
MSGGGERQYRQEASSEESCFLSIITPVYNGADYIEFCIRNVIGQNCPGIEHIIIDGGSTDSTAEIISKYAAVNPHIRWVS
EKDEGQSHAMNKAIAMARGSIVGFLNADDYYEPDILCRIVEIFQGLPAPSLLVGNCNVWDNEGRLWFVSRPAQIGLKNLL
LGRFLEAFPMNPSAYFYHKSLHQRIGMYDTGEHFGMDLQFIFQAVQKAKVTYLDETWGNYRYLEGTKTYEDDKSGGNGTR
VKQMTLRYRQQQPLYYRVYLLAIEAWIRAVRLIRRPFAAEDKL
>Mature_282_residues
SGGGERQYRQEASSEESCFLSIITPVYNGADYIEFCIRNVIGQNCPGIEHIIIDGGSTDSTAEIISKYAAVNPHIRWVSE
KDEGQSHAMNKAIAMARGSIVGFLNADDYYEPDILCRIVEIFQGLPAPSLLVGNCNVWDNEGRLWFVSRPAQIGLKNLLL
GRFLEAFPMNPSAYFYHKSLHQRIGMYDTGEHFGMDLQFIFQAVQKAKVTYLDETWGNYRYLEGTKTYEDDKSGGNGTRV
KQMTLRYRQQQPLYYRVYLLAIEAWIRAVRLIRRPFAAEDKL

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790044, Length=95, Percent_Identity=40, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 32280; Mature: 32149

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGGERQYRQEASSEESCFLSIITPVYNGADYIEFCIRNVIGQNCPGIEHIIIDGGSTD
CCCCCCHHHHHHCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
STAEIISKYAAVNPHIRWVSEKDEGQSHAMNKAIAMARGSIVGFLNADDYYEPDILCRIV
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
EIFQGLPAPSLLVGNCNVWDNEGRLWFVSRPAQIGLKNLLLGRFLEAFPMNPSAYFYHKS
HHHCCCCCCCEEEECCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LHQRIGMYDTGEHFGMDLQFIFQAVQKAKVTYLDETWGNYRYLEGTKTYEDDKSGGNGTR
HHHHCCCCCCCHHHCCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCH
VKQMTLRYRQQQPLYYRVYLLAIEAWIRAVRLIRRPFAAEDKL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGGGERQYRQEASSEESCFLSIITPVYNGADYIEFCIRNVIGQNCPGIEHIIIDGGSTD
CCCCCHHHHHHCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
STAEIISKYAAVNPHIRWVSEKDEGQSHAMNKAIAMARGSIVGFLNADDYYEPDILCRIV
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
EIFQGLPAPSLLVGNCNVWDNEGRLWFVSRPAQIGLKNLLLGRFLEAFPMNPSAYFYHKS
HHHCCCCCCCEEEECCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LHQRIGMYDTGEHFGMDLQFIFQAVQKAKVTYLDETWGNYRYLEGTKTYEDDKSGGNGTR
HHHHCCCCCCCHHHCCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCH
VKQMTLRYRQQQPLYYRVYLLAIEAWIRAVRLIRRPFAAEDKL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11943778 [H]