Click here to switch to the map view.

The map label for this gene is rpfG [H]

Identifier: 197118815

GI number: 197118815

Start: 2826654

End: 2828765

Strand: Direct

Name: rpfG [H]

Synonym: Gbem_2438

Alternate gene names: 197118815

Gene position: 2826654-2828765 (Clockwise)

Preceding gene: 308535303

Following gene: 197118816

Centisome position: 61.25

GC content: 60.46

Gene sequence:

>2112_bases
ATGTTCAACTCCCTAAAGATGAAGATCCTAACCTTGGTGGCCCTGATACTGGTGCTCATCATCTCGTCTGTCGCCTACCT
CAATTTCCAGCAGCAAAAGGAAATGCTGCACGAGATCGCCAACCGGAACACCTCGGTACTGATCGAAACCATCAAAAGCA
GCGTGGCGAACGCGATGCTCTCCGGCCGCTCCGACGAAGTGGGGAGCATCTTCGAGCGGATCAAGTCCAGGGAGTTCGTC
AAATCCATCAGGATCGTCGACGCAGAGGGAAAGATCCTCATCTCGGCTGACCGCGCCGAGGTCGGGAGCAAGATCCCCGA
GCTGGGCGAGAAGCAATCGCAGTCGCGCAACATGACCCTTTTCCCTTCCCAAGGGGTCTTCGTCTCCTACGCCCGTATCT
TCAACGCCCCCCAGTGCTTCAGATGCCACCCGGCCGGCAAGGAAAGCCTGGGGCTTCTGGAAATCAAGCTCTCCCTCGAC
TACATGAACGGCTTCATCTCCCGCGAAAGGGACCTGGCCGTCTTCTCCAGTCTGCTCCTGGTCCTTTTGACCGTGGCCAC
CATCTTCATCTTCCTGGTCATCTACGTCGAGAAGCCGATCCGCAGGCTGATCCGCTGCATGCAGCAGGTGGAGGGTGGCG
ATTTCCGCCAGGAGATCAACCTCACCTCAAGCCTTGAGATGCAGACTCTCGCCAAGAGCTTCAACCACATGGTAAGGACC
CTCGCCTCCTTGATGGAATCCACCGTGGCGCATGAGCGGGAGCTGGCACGGGCGCAGGAGAAGCTCGCCTTCCACCGCGA
GACCCACCAGTTGAACGGCAGGCTCGAGGAGCAGATCCGCGAGATCGAGAACCTGAACGTGAACCTGGAGGAGCGGATCG
AGGAGATCGAGGAGGCGAACTACAAGATCGCGGACCTTGCGGGGGAGTTGGAGGACAAGAACACCAACCTGGAGAAGGCG
GTGGCGAAACTCTCCACCCTGTACCGGCTCGGGCTCGCCATCAACTCGACCATCGAGGTCGAGGACCTGTACCAGCTGGT
GGTGAAGACCACTATGGACACCCTGCAGGCCCAGGTGGGATACATCATCCTTTACGACGCGCTCCACGGCGACCTGAAGG
TGATCAACCTGGTCGGGCACAGAAACCCCAACGTCCAGGCGATGCGCGTGCCGATGAAGCCCTCCAGCGTCTCCAGCTGG
GTGATCCAGAACTGCAAGCCTTTGCTCATCACCGACATCGCGCAGATGCCGGAGTTCGATCCGGTCAGCCCCTTGGGCTT
CGAGCGCAAGACCCTGATCTGCGCGCCGCTCATGGTGAAGGACGAGATGATCGGCACCCTCGCCGTGGTCAACAAGCTGG
ACAACACGGTCTACAACCACGAGGAACTGGAGCTTTTGTCAACCATCGCAGCGCAAGCCTCCATCGCCATCAAAAACGCG
ATGCTCTACGACGAGCAGCAAAAGACCTACTTGAACACCATCCAAGCGCTGGTTTCCGCCATCGAGGCAAGCGACAGCTA
CACCCGCGGCCACTCCGAGCGGGTCACCCGCTTCTCGCTCGCCCTGGCGCGCAAGCTCGAACTGCCGCAGAACCGGCTCA
AGGTGATCGAGCGTGCGGCCATCCTGCACGACATCGGCAAGATCGGGATCGACCTCTCCCTTTTGCACAAGGAGGCGCTC
TTGACCAGCGAGGATGTGGCCGAGCTGCAGCAGCACCCCACCATCGGGATGAAGATCCTGGAACCTATCGAGTTTCTCTA
CGACGTGAGGCTCTGCATCGGCCAGCACCACGAGCGCTACGACGGCACCGGCTACCCGAACCGACTGCGCGCCGAGGAGC
TTCTTTTGGAGTCGCGCATTCTCGCCATCGCCGACGCCTTCGACGCCATGACCTCCGACCGCCCCTACCGCAAGGCGCTG
AAGCTGGAGGTCGCCATCGCGGAACTGGCTGAAAACAGCGGGTCCCAGTTCGACCCCGCCCTGGTCCCTATCTTCATCAA
GCTCCTGAAGACACCCAACTTCCTGCCGCAGCGCGAGGAAACCCCGGGGTTGAACGTGGTTCCTTTCCCTGGCAAGCCTG
CCGGCGGACCCCTGACCTCCGTTGGCCCTTGA

Upstream 100 bases:

>100_bases
GGACCCGGAGAGGGAAATAACTGTTGCCAGAAACGCAAAAACAGGCTATATCGCTGATGAGACTGGTCATTTAGCGTTCA
ACCAAGAAGTCCGGATATAT

Downstream 100 bases:

>100_bases
CGGCAAGTTGTAGAAAGTTTACTTTTGCCGATACCGGTTCCCGCGACGCCTGACGGGAAAGCCCGGCTACGGGAGTGCCT
TTGTCGCCTTTACTTGAAAT

Product: sensor cyclic diguanylate phosphodiesterase, HAMP/GAF domain-containing heme-binding site

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MFNSLKMKILTLVALILVLIISSVAYLNFQQQKEMLHEIANRNTSVLIETIKSSVANAMLSGRSDEVGSIFERIKSREFV
KSIRIVDAEGKILISADRAEVGSKIPELGEKQSQSRNMTLFPSQGVFVSYARIFNAPQCFRCHPAGKESLGLLEIKLSLD
YMNGFISRERDLAVFSSLLLVLLTVATIFIFLVIYVEKPIRRLIRCMQQVEGGDFRQEINLTSSLEMQTLAKSFNHMVRT
LASLMESTVAHERELARAQEKLAFHRETHQLNGRLEEQIREIENLNVNLEERIEEIEEANYKIADLAGELEDKNTNLEKA
VAKLSTLYRLGLAINSTIEVEDLYQLVVKTTMDTLQAQVGYIILYDALHGDLKVINLVGHRNPNVQAMRVPMKPSSVSSW
VIQNCKPLLITDIAQMPEFDPVSPLGFERKTLICAPLMVKDEMIGTLAVVNKLDNTVYNHEELELLSTIAAQASIAIKNA
MLYDEQQKTYLNTIQALVSAIEASDSYTRGHSERVTRFSLALARKLELPQNRLKVIERAAILHDIGKIGIDLSLLHKEAL
LTSEDVAELQQHPTIGMKILEPIEFLYDVRLCIGQHHERYDGTGYPNRLRAEELLLESRILAIADAFDAMTSDRPYRKAL
KLEVAIAELAENSGSQFDPALVPIFIKLLKTPNFLPQREETPGLNVVPFPGKPAGGPLTSVGP

Sequences:

>Translated_703_residues
MFNSLKMKILTLVALILVLIISSVAYLNFQQQKEMLHEIANRNTSVLIETIKSSVANAMLSGRSDEVGSIFERIKSREFV
KSIRIVDAEGKILISADRAEVGSKIPELGEKQSQSRNMTLFPSQGVFVSYARIFNAPQCFRCHPAGKESLGLLEIKLSLD
YMNGFISRERDLAVFSSLLLVLLTVATIFIFLVIYVEKPIRRLIRCMQQVEGGDFRQEINLTSSLEMQTLAKSFNHMVRT
LASLMESTVAHERELARAQEKLAFHRETHQLNGRLEEQIREIENLNVNLEERIEEIEEANYKIADLAGELEDKNTNLEKA
VAKLSTLYRLGLAINSTIEVEDLYQLVVKTTMDTLQAQVGYIILYDALHGDLKVINLVGHRNPNVQAMRVPMKPSSVSSW
VIQNCKPLLITDIAQMPEFDPVSPLGFERKTLICAPLMVKDEMIGTLAVVNKLDNTVYNHEELELLSTIAAQASIAIKNA
MLYDEQQKTYLNTIQALVSAIEASDSYTRGHSERVTRFSLALARKLELPQNRLKVIERAAILHDIGKIGIDLSLLHKEAL
LTSEDVAELQQHPTIGMKILEPIEFLYDVRLCIGQHHERYDGTGYPNRLRAEELLLESRILAIADAFDAMTSDRPYRKAL
KLEVAIAELAENSGSQFDPALVPIFIKLLKTPNFLPQREETPGLNVVPFPGKPAGGPLTSVGP
>Mature_703_residues
MFNSLKMKILTLVALILVLIISSVAYLNFQQQKEMLHEIANRNTSVLIETIKSSVANAMLSGRSDEVGSIFERIKSREFV
KSIRIVDAEGKILISADRAEVGSKIPELGEKQSQSRNMTLFPSQGVFVSYARIFNAPQCFRCHPAGKESLGLLEIKLSLD
YMNGFISRERDLAVFSSLLLVLLTVATIFIFLVIYVEKPIRRLIRCMQQVEGGDFRQEINLTSSLEMQTLAKSFNHMVRT
LASLMESTVAHERELARAQEKLAFHRETHQLNGRLEEQIREIENLNVNLEERIEEIEEANYKIADLAGELEDKNTNLEKA
VAKLSTLYRLGLAINSTIEVEDLYQLVVKTTMDTLQAQVGYIILYDALHGDLKVINLVGHRNPNVQAMRVPMKPSSVSSW
VIQNCKPLLITDIAQMPEFDPVSPLGFERKTLICAPLMVKDEMIGTLAVVNKLDNTVYNHEELELLSTIAAQASIAIKNA
MLYDEQQKTYLNTIQALVSAIEASDSYTRGHSERVTRFSLALARKLELPQNRLKVIERAAILHDIGKIGIDLSLLHKEAL
LTSEDVAELQQHPTIGMKILEPIEFLYDVRLCIGQHHERYDGTGYPNRLRAEELLLESRILAIADAFDAMTSDRPYRKAL
KLEVAIAELAENSGSQFDPALVPIFIKLLKTPNFLPQREETPGLNVVPFPGKPAGGPLTSVGP

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 78854; Mature: 78854

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSLKMKILTLVALILVLIISSVAYLNFQQQKEMLHEIANRNTSVLIETIKSSVANAML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SGRSDEVGSIFERIKSREFVKSIRIVDAEGKILISADRAEVGSKIPELGEKQSQSRNMTL
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECHHHHCCCCHHHCCHHHCCCCEEE
FPSQGVFVSYARIFNAPQCFRCHPAGKESLGLLEIKLSLDYMNGFISRERDLAVFSSLLL
ECCCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHH
VLLTVATIFIFLVIYVEKPIRRLIRCMQQVEGGDFRQEINLTSSLEMQTLAKSFNHMVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
LASLMESTVAHERELARAQEKLAFHRETHQLNGRLEEQIREIENLNVNLEERIEEIEEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
YKIADLAGELEDKNTNLEKAVAKLSTLYRLGLAINSTIEVEDLYQLVVKTTMDTLQAQVG
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
YIILYDALHGDLKVINLVGHRNPNVQAMRVPMKPSSVSSWVIQNCKPLLITDIAQMPEFD
EEEEEECCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCCCC
PVSPLGFERKTLICAPLMVKDEMIGTLAVVNKLDNTVYNHEELELLSTIAAQASIAIKNA
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MLYDEQQKTYLNTIQALVSAIEASDSYTRGHSERVTRFSLALARKLELPQNRLKVIERAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILHDIGKIGIDLSLLHKEALLTSEDVAELQQHPTIGMKILEPIEFLYDVRLCIGQHHERY
HHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
DGTGYPNRLRAEELLLESRILAIADAFDAMTSDRPYRKALKLEVAIAELAENSGSQFDPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
LVPIFIKLLKTPNFLPQREETPGLNVVPFPGKPAGGPLTSVGP
HHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MFNSLKMKILTLVALILVLIISSVAYLNFQQQKEMLHEIANRNTSVLIETIKSSVANAML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SGRSDEVGSIFERIKSREFVKSIRIVDAEGKILISADRAEVGSKIPELGEKQSQSRNMTL
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECHHHHCCCCHHHCCHHHCCCCEEE
FPSQGVFVSYARIFNAPQCFRCHPAGKESLGLLEIKLSLDYMNGFISRERDLAVFSSLLL
ECCCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHH
VLLTVATIFIFLVIYVEKPIRRLIRCMQQVEGGDFRQEINLTSSLEMQTLAKSFNHMVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
LASLMESTVAHERELARAQEKLAFHRETHQLNGRLEEQIREIENLNVNLEERIEEIEEAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
YKIADLAGELEDKNTNLEKAVAKLSTLYRLGLAINSTIEVEDLYQLVVKTTMDTLQAQVG
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
YIILYDALHGDLKVINLVGHRNPNVQAMRVPMKPSSVSSWVIQNCKPLLITDIAQMPEFD
EEEEEECCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCCCC
PVSPLGFERKTLICAPLMVKDEMIGTLAVVNKLDNTVYNHEELELLSTIAAQASIAIKNA
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MLYDEQQKTYLNTIQALVSAIEASDSYTRGHSERVTRFSLALARKLELPQNRLKVIERAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ILHDIGKIGIDLSLLHKEALLTSEDVAELQQHPTIGMKILEPIEFLYDVRLCIGQHHERY
HHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
DGTGYPNRLRAEELLLESRILAIADAFDAMTSDRPYRKALKLEVAIAELAENSGSQFDPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
LVPIFIKLLKTPNFLPQREETPGLNVVPFPGKPAGGPLTSVGP
HHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]