Click here to switch to the map view.

The map label for this gene is stc [H]

Identifier: 197118791

GI number: 197118791

Start: 2794929

End: 2796383

Strand: Reverse

Name: stc [H]

Synonym: Gbem_2412

Alternate gene names: 197118791

Gene position: 2796383-2794929 (Counterclockwise)

Preceding gene: 197118792

Following gene: 197118790

Centisome position: 60.59

GC content: 59.86

Gene sequence:

>1455_bases
ATGACTGACCCGGTTATGGAAAATCTTTCTACGCTCGATCTCGAGGAGATGGCGCGCCAGATGCGGGCGTTCCAGGATCT
GACCCGCGAGCTGGATGCGATCATCGATTCGTCCTCGGACGGCCTCTGGATCTGCGACGCCGAGGCCCGAGTCATCCGCA
TCAACCCTGCCTCGGAGCGGATCAACAACATAAAGGCGTCGGAAGTTGTCGGCAAGAACATGCGGAAACTTCTGGATGAA
GGTTTCATAGACCGCTCGGCGGCGCTCGAGGCGATCACCACCAAGAAGGTGGTCAGCCAACTGCAGAACAGGGAAGGGCG
CAAGCTCATCTCGACGGGGACTCCGGTTCTGGACGCAAACGGCGAGGTGATCCGGGTCGTGGTAAGCGAGCGGGACATCA
CGGAGATCGATAACTTGCAGCGCGAACTGGAAGAGCAGGAGGCGCTGCGGGATCAGTTCCGTAACCACATGCTGGAACTT
CAGCAGGCAGACGTGGCCTCCAAGAGCGTCGTCGCCCGCAGTCCGCTGATGGTGAACGCCCTGAAGCAGGCGCTTAAAGT
GAGCGCGGTCAACTCGACGGTGCTGATTCTCGGGGAGTCGGGCGTTGGCAAGGGGCTCATTGCCGAGTTGATACACAAGA
ATTCCACCAGGGCCGACAAGCCTCTCATCGAGATAAACTGCGGTGCCATACCGGAGTCGCTGATAGAGTCGGAGCTCTTC
GGTTACGAGAAGGGAGCCTTTACCGGTGCGCAGACGACTGGCAAACCCGGCTATTTGGAACTTGCCGACGGCGGCATCCT
GTTCCTGGACGAGATCGCGGAGTTGCCGCAGTCGGCGCAGGTGAAGCTGCTGCGCTTCCTCGAAAACGGGAAGGTGATCC
GCTTGGGAGGGACCAAGGCCAGGCATCTGGACGTCCGCATCCTGGCGGCGACGCACCGCAATCTGGACGAGATGGTGCGG
CAGGGAAGCTTCAGGCTGGACCTTTATTACCGGCTCAACGTGATCCCCATCAGCGTTCCGGCTTTGCGCGAGCGGCGGGA
CTGCATTTTGCCGCTGGTAAGACACTACCTGGAACTTTTCGGCGCTCGCGACTCCATTCGCAAGCGTATCACCCGTGCCG
CCTCCGATGCGCTTCTTGCCTACGACTACCCGGGAAACGTGCGTCAGTTGATGAACGTCTGCGAGCGGCTCGTGGTCATG
GCGGAAACGGACCTGATCGACGTGAAGGATCTCCCTGCTGAGATCTCTGCCGGCGCCGGTAAGCCGACCGCGGTGGCCGG
GGTCTGGCAGGAGGATGTGCCGCTGCAGGAGACGCTGGATCAGGTCGAGAAGGCCGTCCTGGAAAAGGCGCTGGCCAAAC
ACCGCAACCAAATGCGCATGGCTGAGGTTCTTGGGGTGAACCAATCGACCATTGCAAGGAAACTTAGGAAATACAAGCTG
ATTAACCCCAATTGA

Upstream 100 bases:

>100_bases
GTCCCCTTTTCCTTTTTTGTTGTTATTCGTTATTGCATATCTAATGCATTCATGCATAATGCCTGTCGGCGATACTCTCA
GCCCCAGTTTAGGAGAGACG

Downstream 100 bases:

>100_bases
CCTGAACCCCAATTGACAATTGACGATTGACAATTGACAATTGACAAAGCAAGGCGAACACCACGAACTTCAATTGACAA
AGTAAGACAACCACCATAGC

Product: sigma-54-dependent sensor transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTDPVMENLSTLDLEEMARQMRAFQDLTRELDAIIDSSSDGLWICDAEARVIRINPASERINNIKASEVVGKNMRKLLDE
GFIDRSAALEAITTKKVVSQLQNREGRKLISTGTPVLDANGEVIRVVVSERDITEIDNLQRELEEQEALRDQFRNHMLEL
QQADVASKSVVARSPLMVNALKQALKVSAVNSTVLILGESGVGKGLIAELIHKNSTRADKPLIEINCGAIPESLIESELF
GYEKGAFTGAQTTGKPGYLELADGGILFLDEIAELPQSAQVKLLRFLENGKVIRLGGTKARHLDVRILAATHRNLDEMVR
QGSFRLDLYYRLNVIPISVPALRERRDCILPLVRHYLELFGARDSIRKRITRAASDALLAYDYPGNVRQLMNVCERLVVM
AETDLIDVKDLPAEISAGAGKPTAVAGVWQEDVPLQETLDQVEKAVLEKALAKHRNQMRMAEVLGVNQSTIARKLRKYKL
INPN

Sequences:

>Translated_484_residues
MTDPVMENLSTLDLEEMARQMRAFQDLTRELDAIIDSSSDGLWICDAEARVIRINPASERINNIKASEVVGKNMRKLLDE
GFIDRSAALEAITTKKVVSQLQNREGRKLISTGTPVLDANGEVIRVVVSERDITEIDNLQRELEEQEALRDQFRNHMLEL
QQADVASKSVVARSPLMVNALKQALKVSAVNSTVLILGESGVGKGLIAELIHKNSTRADKPLIEINCGAIPESLIESELF
GYEKGAFTGAQTTGKPGYLELADGGILFLDEIAELPQSAQVKLLRFLENGKVIRLGGTKARHLDVRILAATHRNLDEMVR
QGSFRLDLYYRLNVIPISVPALRERRDCILPLVRHYLELFGARDSIRKRITRAASDALLAYDYPGNVRQLMNVCERLVVM
AETDLIDVKDLPAEISAGAGKPTAVAGVWQEDVPLQETLDQVEKAVLEKALAKHRNQMRMAEVLGVNQSTIARKLRKYKL
INPN
>Mature_483_residues
TDPVMENLSTLDLEEMARQMRAFQDLTRELDAIIDSSSDGLWICDAEARVIRINPASERINNIKASEVVGKNMRKLLDEG
FIDRSAALEAITTKKVVSQLQNREGRKLISTGTPVLDANGEVIRVVVSERDITEIDNLQRELEEQEALRDQFRNHMLELQ
QADVASKSVVARSPLMVNALKQALKVSAVNSTVLILGESGVGKGLIAELIHKNSTRADKPLIEINCGAIPESLIESELFG
YEKGAFTGAQTTGKPGYLELADGGILFLDEIAELPQSAQVKLLRFLENGKVIRLGGTKARHLDVRILAATHRNLDEMVRQ
GSFRLDLYYRLNVIPISVPALRERRDCILPLVRHYLELFGARDSIRKRITRAASDALLAYDYPGNVRQLMNVCERLVVMA
ETDLIDVKDLPAEISAGAGKPTAVAGVWQEDVPLQETLDQVEKAVLEKALAKHRNQMRMAEVLGVNQSTIARKLRKYKLI
NPN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=362, Percent_Identity=41.1602209944751, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789233, Length=488, Percent_Identity=32.172131147541, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1790437, Length=346, Percent_Identity=42.1965317919075, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1790299, Length=360, Percent_Identity=38.3333333333333, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI87082117, Length=267, Percent_Identity=45.6928838951311, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788905, Length=243, Percent_Identity=47.3251028806584, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=38.7692307692308, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=37.3831775700935, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786524, Length=244, Percent_Identity=42.6229508196721, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789087, Length=295, Percent_Identity=41.6949152542373, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=37.6582278481013, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI87081858, Length=453, Percent_Identity=26.2693156732892, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789828, Length=284, Percent_Identity=29.9295774647887, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53828; Mature: 53697

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPVMENLSTLDLEEMARQMRAFQDLTRELDAIIDSSSDGLWICDAEARVIRINPASER
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCHHHH
INNIKASEVVGKNMRKLLDEGFIDRSAALEAITTKKVVSQLQNREGRKLISTGTPVLDAN
HHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECC
GEVIRVVVSERDITEIDNLQRELEEQEALRDQFRNHMLELQQADVASKSVVARSPLMVNA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LKQALKVSAVNSTVLILGESGVGKGLIAELIHKNSTRADKPLIEINCGAIPESLIESELF
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHH
GYEKGAFTGAQTTGKPGYLELADGGILFLDEIAELPQSAQVKLLRFLENGKVIRLGGTKA
CCCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCE
RHLDVRILAATHRNLDEMVRQGSFRLDLYYRLNVIPISVPALRERRDCILPLVRHYLELF
EEEEEEEEEHHHCCHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GARDSIRKRITRAASDALLAYDYPGNVRQLMNVCERLVVMAETDLIDVKDLPAEISAGAG
CCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHCCCCC
KPTAVAGVWQEDVPLQETLDQVEKAVLEKALAKHRNQMRMAEVLGVNQSTIARKLRKYKL
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
INPN
CCCC
>Mature Secondary Structure 
TDPVMENLSTLDLEEMARQMRAFQDLTRELDAIIDSSSDGLWICDAEARVIRINPASER
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCHHHH
INNIKASEVVGKNMRKLLDEGFIDRSAALEAITTKKVVSQLQNREGRKLISTGTPVLDAN
HHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECC
GEVIRVVVSERDITEIDNLQRELEEQEALRDQFRNHMLELQQADVASKSVVARSPLMVNA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LKQALKVSAVNSTVLILGESGVGKGLIAELIHKNSTRADKPLIEINCGAIPESLIESELF
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHH
GYEKGAFTGAQTTGKPGYLELADGGILFLDEIAELPQSAQVKLLRFLENGKVIRLGGTKA
CCCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCE
RHLDVRILAATHRNLDEMVRQGSFRLDLYYRLNVIPISVPALRERRDCILPLVRHYLELF
EEEEEEEEEHHHCCHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
GARDSIRKRITRAASDALLAYDYPGNVRQLMNVCERLVVMAETDLIDVKDLPAEISAGAG
CCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHCCCCC
KPTAVAGVWQEDVPLQETLDQVEKAVLEKALAKHRNQMRMAEVLGVNQSTIARKLRKYKL
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
INPN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA