Click here to switch to the map view.

The map label for this gene is fdhD/mobA [H]

Identifier: 197118645

GI number: 197118645

Start: 2632077

End: 2633483

Strand: Reverse

Name: fdhD/mobA [H]

Synonym: Gbem_2264

Alternate gene names: 197118645

Gene position: 2633483-2632077 (Counterclockwise)

Preceding gene: 197118646

Following gene: 197118644

Centisome position: 57.06

GC content: 61.83

Gene sequence:

>1407_bases
GTGGCTAGCAAGATCTACAGTTTCAATAAAGGCGTGCTGGAGCAGGAAGAGGGCGGGGTAGTCAACGAATACCCGCTGCA
ACTGGTGGTGAACGGGCGTGAACTGGCGACCCTCATCGCCTCGCCTCACGATCTCCGCTTCCTGGTGGCGGGCTTTCTGC
GCCTGCAGGGGTTCGTCTCACAGGTGGAGGACTTCCAGGCCTTGGCCATCTGCCAGGATTTCGGTGCCGCCAGCGTCACC
ATCCGGGGAGAGCTCCCCGAGCGCCTGAAGCCGGTGCTCACCTCCGGCTGCGGCACCGGCATCAGCTTCAACATGCCCAA
GCCCGTCGAGAAAAAGGGGCCCTCCCGGGTCCATTCCACCGCCTCGATCTTCACGCTGATGAACCAACTGGCGCAGAAGG
CGGAAGGGTACAAAAGCCATGGCGGCATGCACTCGGCAGGGGTCGGCGATACCGAACTCATCCTGCACGCAGAAGATATC
GGCCGCCACAACACCATCGACCGTATAGCAGGAGAGGCCCTCTTGAAGGGGATTTCGCTGGAAGGAAAGATTCTGGTCAC
TTCGGGACGCGTTTCGACCGAGCTGGTGGCAAAGGCTTCGCTTCTCGGCATCGACGTGATCGCTTCCCGCACCTCGCCTA
CCGACATGGCGATCAAGATGGCCGAAGAGGCCGGCATTACGCTGGTCGGCTACGTCAGGGCCATGAGCTTCAAGCTCTAC
ACCCACGTCGAGGGGATCGATTTCCGCGCCGGCGACGGCAAGATCCAGGGGGTGACCGGCGTTATCCTTGCCGGTGGCGC
CTCCAGCCGTATGGGGAGCAACAAGGCTCTGCTGCCGCACAAGGGAGGGCGCTTCATAGAAAGCATCTACCGGGAGCTTT
GCGAGATCTTCCCCGAGGTGATCCTGGTAACCAACGCCCCGGAGCAATACCAGTTCCTGCCCTGCCGGAAGGTCCCCGAC
CTGTACGAGGGGATGGGTGCCCTGGCGGGTATCCACGCGGGGCTTTCCCAGAGTTCGAACCCGGCCGTCTTCACCGTGGC
GTGCGACATGCCGCACCTGAATCCGGCGCTGATCAGGCACATCGCGAGCCACCGCTACGGCTGCGACTTGGTGCTCCCCA
TGAGCCCGCAGGGCTACGAGCCGCTGCACGCGCTGTACAACAAGGGGTGTCTGCCGGCCATGGAGTCTTCGCTCAAAAAC
GGCAAGCGCCGCATCGTTTCCATCCTGCCACGGGTGAACGTGCGCGAAATAAGCCCCTCGGAGGTGGCCGGTTTCGACCC
CCGCTTCGATTCCTTCAGCAACATCAATACGCCGCAGGAATACTACGACTTAAGAAACGCCGACAAGGAAAAGGCGGCCT
CAGGCGAGCCCTATTCCGATGCAGCTCAGCAAAAACTGCAGGCTTGA

Upstream 100 bases:

>100_bases
TGAGGGTAACAGAACGTCACACAGCAGCGCCCTCACCCCGCCCTCTGCCAAAGGGCGAGGGAGAGTGGACGCGAGTCGGC
TGACAGCGAGGAGCAACCCG

Downstream 100 bases:

>100_bases
ATTTGAAAGCGACCCCGGGCCAAAGGCATCGGGGCTCACATAAAACCAACGAAACATCGAACCGGTAAGGCGGTTCTTTA
AAGGAGAAGTTAAATGTTTG

Product: bifunctional formate dehydrogenase accessory protein FdhD/molybdopterin-guanine dinucleotide biosynthesis protein MobA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MASKIYSFNKGVLEQEEGGVVNEYPLQLVVNGRELATLIASPHDLRFLVAGFLRLQGFVSQVEDFQALAICQDFGAASVT
IRGELPERLKPVLTSGCGTGISFNMPKPVEKKGPSRVHSTASIFTLMNQLAQKAEGYKSHGGMHSAGVGDTELILHAEDI
GRHNTIDRIAGEALLKGISLEGKILVTSGRVSTELVAKASLLGIDVIASRTSPTDMAIKMAEEAGITLVGYVRAMSFKLY
THVEGIDFRAGDGKIQGVTGVILAGGASSRMGSNKALLPHKGGRFIESIYRELCEIFPEVILVTNAPEQYQFLPCRKVPD
LYEGMGALAGIHAGLSQSSNPAVFTVACDMPHLNPALIRHIASHRYGCDLVLPMSPQGYEPLHALYNKGCLPAMESSLKN
GKRRIVSILPRVNVREISPSEVAGFDPRFDSFSNINTPQEYYDLRNADKEKAASGEPYSDAAQQKLQA

Sequences:

>Translated_468_residues
MASKIYSFNKGVLEQEEGGVVNEYPLQLVVNGRELATLIASPHDLRFLVAGFLRLQGFVSQVEDFQALAICQDFGAASVT
IRGELPERLKPVLTSGCGTGISFNMPKPVEKKGPSRVHSTASIFTLMNQLAQKAEGYKSHGGMHSAGVGDTELILHAEDI
GRHNTIDRIAGEALLKGISLEGKILVTSGRVSTELVAKASLLGIDVIASRTSPTDMAIKMAEEAGITLVGYVRAMSFKLY
THVEGIDFRAGDGKIQGVTGVILAGGASSRMGSNKALLPHKGGRFIESIYRELCEIFPEVILVTNAPEQYQFLPCRKVPD
LYEGMGALAGIHAGLSQSSNPAVFTVACDMPHLNPALIRHIASHRYGCDLVLPMSPQGYEPLHALYNKGCLPAMESSLKN
GKRRIVSILPRVNVREISPSEVAGFDPRFDSFSNINTPQEYYDLRNADKEKAASGEPYSDAAQQKLQA
>Mature_467_residues
ASKIYSFNKGVLEQEEGGVVNEYPLQLVVNGRELATLIASPHDLRFLVAGFLRLQGFVSQVEDFQALAICQDFGAASVTI
RGELPERLKPVLTSGCGTGISFNMPKPVEKKGPSRVHSTASIFTLMNQLAQKAEGYKSHGGMHSAGVGDTELILHAEDIG
RHNTIDRIAGEALLKGISLEGKILVTSGRVSTELVAKASLLGIDVIASRTSPTDMAIKMAEEAGITLVGYVRAMSFKLYT
HVEGIDFRAGDGKIQGVTGVILAGGASSRMGSNKALLPHKGGRFIESIYRELCEIFPEVILVTNAPEQYQFLPCRKVPDL
YEGMGALAGIHAGLSQSSNPAVFTVACDMPHLNPALIRHIASHRYGCDLVLPMSPQGYEPLHALYNKGCLPAMESSLKNG
KRRIVSILPRVNVREISPSEVAGFDPRFDSFSNINTPQEYYDLRNADKEKAASGEPYSDAAQQKLQA

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family [H]

Homologues:

Organism=Escherichia coli, GI1790329, Length=235, Percent_Identity=25.9574468085106, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790288, Length=186, Percent_Identity=26.8817204301075, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003786 [H]

Pfam domain/function: PF02634 FdhD-NarQ [H]

EC number: NA

Molecular weight: Translated: 50525; Mature: 50393

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKIYSFNKGVLEQEEGGVVNEYPLQLVVNGRELATLIASPHDLRFLVAGFLRLQGFVS
CCCCCCCCCCCCCCCCCCCCEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVEDFQALAICQDFGAASVTIRGELPERLKPVLTSGCGTGISFNMPKPVEKKGPSRVHST
HHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHH
ASIFTLMNQLAQKAEGYKSHGGMHSAGVGDTELILHAEDIGRHNTIDRIAGEALLKGISL
HHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHCCCC
EGKILVTSGRVSTELVAKASLLGIDVIASRTSPTDMAIKMAEEAGITLVGYVRAMSFKLY
CCEEEEECCCCHHHHHHHHHHHHHHEEECCCCCHHHHHEEHHHCCCEEEEHHHHHHEEEE
THVEGIDFRAGDGKIQGVTGVILAGGASSRMGSNKALLPHKGGRFIESIYRELCEIFPEV
EEECCCEEECCCCEECCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHE
ILVTNAPEQYQFLPCRKVPDLYEGMGALAGIHAGLSQSSNPAVFTVACDMPHLNPALIRH
EEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHH
IASHRYGCDLVLPMSPQGYEPLHALYNKGCLPAMESSLKNGKRRIVSILPRVNVREISPS
HHHCCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
EVAGFDPRFDSFSNINTPQEYYDLRNADKEKAASGEPYSDAAQQKLQA
HCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
ASKIYSFNKGVLEQEEGGVVNEYPLQLVVNGRELATLIASPHDLRFLVAGFLRLQGFVS
CCCCCCCCCCCCCCCCCCCEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVEDFQALAICQDFGAASVTIRGELPERLKPVLTSGCGTGISFNMPKPVEKKGPSRVHST
HHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHH
ASIFTLMNQLAQKAEGYKSHGGMHSAGVGDTELILHAEDIGRHNTIDRIAGEALLKGISL
HHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHCCCC
EGKILVTSGRVSTELVAKASLLGIDVIASRTSPTDMAIKMAEEAGITLVGYVRAMSFKLY
CCEEEEECCCCHHHHHHHHHHHHHHEEECCCCCHHHHHEEHHHCCCEEEEHHHHHHEEEE
THVEGIDFRAGDGKIQGVTGVILAGGASSRMGSNKALLPHKGGRFIESIYRELCEIFPEV
EEECCCEEECCCCEECCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHE
ILVTNAPEQYQFLPCRKVPDLYEGMGALAGIHAGLSQSSNPAVFTVACDMPHLNPALIRH
EEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHH
IASHRYGCDLVLPMSPQGYEPLHALYNKGCLPAMESSLKNGKRRIVSILPRVNVREISPS
HHHCCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
EVAGFDPRFDSFSNINTPQEYYDLRNADKEKAASGEPYSDAAQQKLQA
HCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA