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The map label for this gene is degS [H]

Identifier: 197118635

GI number: 197118635

Start: 2623115

End: 2624341

Strand: Direct

Name: degS [H]

Synonym: Gbem_2254

Alternate gene names: 197118635

Gene position: 2623115-2624341 (Clockwise)

Preceding gene: 197118628

Following gene: 197118642

Centisome position: 56.84

GC content: 46.21

Gene sequence:

>1227_bases
ATGGACAGTATCGAGGACATCCAAAGCAAAAAAAAGACAGTTTCCAAAAAGCAATTCCCGTCAGATAGGAAGCTCCATAA
CCTTTTACGACACGTGCCGGTAGTGCTGTTTCAGTACCAAAAGCATGGCGACGGTCGTCATAGCTTTCCGTATATCAGCG
ACGGCTTGACGAAACTTTTTCATGTTCGTTCCTGCAAGGCGCCAACAGATGCTTCTGGTTTTTTTTCAAAGCTTCACTGC
GATGATGTGGGTATTGTCATTGCGTCACTCGCCGACTCGGCAGAGAACCTATCTCTTTGGCAACAGGAGTTTCGTATCAA
AATGGAGCGGCAATATTGGATAGAGGCAGCGGCCACTCCAATCTTGCTAAAGGATGGTAGTTACTTGTGGAGTGGGTATG
CGAGAGAGATAAGCGAGAGAAAGGTATTGGAGCAGGATTTAAGGAAAGCTAAGGAAGACTTAATGCGGCTGATAGAGGAA
CGGACCCATAAGCTGACTAAAGCCAACACAAAACTGCACGCCCTAAACCAGGAGATAAGAGAAGAGATTGACCAGCGCGT
CAAACTAGAGAAAAGTCTAAAAGAATCGTATGAGCTTTTGTCTTTGCTTGCCGCGAATCTAGTCTTCTCGGAAGAACGAG
AGCGGAGAAGAATTGCAACAGAATTGCATGATGATGTGGTGCAGCATCTGGCGCTTTGCAAACTCAGACTCGATATGGGA
CTCAAGGACGGGACTCCCTCGCGTGTATTGCAGGAAGAACTTGTCGGCGAACTTGTAAGGACAATGCAACAGATCAGACG
CATCTGCTACGACCTAAGCCCTCCAGTGCTGTACGATTTTGGAATTCTTAAAGCGCTGCAAAATCTCGGAGAAACAATGA
CCCAGGCAGCCGCTTTACAATTTTCATTTCAACACGACCAGGAAAAGCTTGAATTACCAAATCATATATGCACTGTACTG
TATCAAACGGCCAAAGAGTTGCTTACTAATGTGATAAAACATGCAACTGCGAGCCAAATATTGGTAACCATAACAAAAAG
TGACGAATTGGTCAGGCTATCGGTAACCGACGACGGAGTTGGCTTCTTATCTTCTTGCAAGAAGGGTTTTGGGTTGTCAC
ATATTCAGCAAAGGGTAGCCTTCCTCAAAGGGAACCTGAGCATCTCCTCAGGACCCGACAAAAAGACTGTTGTGACAGTC
GAAATCCCTGCGCCCGGCCCGAATTAA

Upstream 100 bases:

>100_bases
GTGCTGAAACAGCCGCTCATAAAAAAACTTTTAAAATTTAACAATATAAATTATATTGCTGTCATACAAGACACGATCGC
TACCGAGTCAAGGGCTGACA

Downstream 100 bases:

>100_bases
TTAATTTTATTTAGCCGCTCACTATACTCTAAGACATATCGTTTAACCTTGGGGTTGTGCAAGTTGAAGTGCTCAAGGCT
CCAGTCGTTCAAGAACTGCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MDSIEDIQSKKKTVSKKQFPSDRKLHNLLRHVPVVLFQYQKHGDGRHSFPYISDGLTKLFHVRSCKAPTDASGFFSKLHC
DDVGIVIASLADSAENLSLWQQEFRIKMERQYWIEAAATPILLKDGSYLWSGYAREISERKVLEQDLRKAKEDLMRLIEE
RTHKLTKANTKLHALNQEIREEIDQRVKLEKSLKESYELLSLLAANLVFSEERERRRIATELHDDVVQHLALCKLRLDMG
LKDGTPSRVLQEELVGELVRTMQQIRRICYDLSPPVLYDFGILKALQNLGETMTQAAALQFSFQHDQEKLELPNHICTVL
YQTAKELLTNVIKHATASQILVTITKSDELVRLSVTDDGVGFLSSCKKGFGLSHIQQRVAFLKGNLSISSGPDKKTVVTV
EIPAPGPN

Sequences:

>Translated_408_residues
MDSIEDIQSKKKTVSKKQFPSDRKLHNLLRHVPVVLFQYQKHGDGRHSFPYISDGLTKLFHVRSCKAPTDASGFFSKLHC
DDVGIVIASLADSAENLSLWQQEFRIKMERQYWIEAAATPILLKDGSYLWSGYAREISERKVLEQDLRKAKEDLMRLIEE
RTHKLTKANTKLHALNQEIREEIDQRVKLEKSLKESYELLSLLAANLVFSEERERRRIATELHDDVVQHLALCKLRLDMG
LKDGTPSRVLQEELVGELVRTMQQIRRICYDLSPPVLYDFGILKALQNLGETMTQAAALQFSFQHDQEKLELPNHICTVL
YQTAKELLTNVIKHATASQILVTITKSDELVRLSVTDDGVGFLSSCKKGFGLSHIQQRVAFLKGNLSISSGPDKKTVVTV
EIPAPGPN
>Mature_408_residues
MDSIEDIQSKKKTVSKKQFPSDRKLHNLLRHVPVVLFQYQKHGDGRHSFPYISDGLTKLFHVRSCKAPTDASGFFSKLHC
DDVGIVIASLADSAENLSLWQQEFRIKMERQYWIEAAATPILLKDGSYLWSGYAREISERKVLEQDLRKAKEDLMRLIEE
RTHKLTKANTKLHALNQEIREEIDQRVKLEKSLKESYELLSLLAANLVFSEERERRRIATELHDDVVQHLALCKLRLDMG
LKDGTPSRVLQEELVGELVRTMQQIRRICYDLSPPVLYDFGILKALQNLGETMTQAAALQFSFQHDQEKLELPNHICTVL
YQTAKELLTNVIKHATASQILVTITKSDELVRLSVTDDGVGFLSSCKKGFGLSHIQQRVAFLKGNLSISSGPDKKTVVTV
EIPAPGPN

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46371; Mature: 46371

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure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HHHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]