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The map label for this gene is nreC [H]

Identifier: 197118634

GI number: 197118634

Start: 2622230

End: 2622880

Strand: Reverse

Name: nreC [H]

Synonym: Gbem_2253

Alternate gene names: 197118634

Gene position: 2622880-2622230 (Counterclockwise)

Preceding gene: 197118636

Following gene: 197118633

Centisome position: 56.83

GC content: 47.47

Gene sequence:

>651_bases
ATGGGCATCAGGATAATATTAGCTGATGATCACGTCATGTTTAGGGAAGGAATGCGTGCGCTTTTGGAACGCGAAGAAGA
TATGGTGGTGGTTGCAGAGGCCGGTGATGGGGTCTCGGTGGTCGAGAAGACTCTTGAAAATATGCCGGATGTAGTGGTTC
TGGACTTGAGCATGCCAGGTATGAATGGGACCGAGGCTGCCAGCGTCATTCACCAAAAAGTTCCGGGGATAGGAATAATC
ATCCTCTCAATGCACAGTGACCGACAGTATGTCATCGAGGCTCTAAAGTTAGGGGTTAAATCGTTCATTCTGAAAGAGTG
GGCTTTTCAGGAATTGGTAACTGCAGTTCGCTGCGTTTTTAAAGACACTTCATATCTAAGTCCCCGTCTGAGTGACATAA
TAATTTCTGGCCTTGCTGATGAGGGAAAGCCTCTCGGCAAGTATAGCCTAACCCCACGTGAGGAGCAGGCATACCGGTTG
CTGGTCGCGGGCAAAAATTGCAAAGAGATCGGCTATGAGCTCAAAATTTCTAGCAAAACAGTCGAGACTTACAGGCTGAA
GGTCATGAAAAAGCTAAATATCTCGAACATAGCACAGCTCGTCAATCACGCAGTGCAAGAGGGCATAGTCGGAAGACCTG
AATCCTTTTGA

Upstream 100 bases:

>100_bases
ATATATTGTTGACCTTTATCTTTGACTGTGGTACCTATTGCAACGATACATAAGTCAATGTTAATACGGGTGGCGGGTCC
CATCTGGTAAGGGGGGAGGA

Downstream 100 bases:

>100_bases
CTGCACAACCCCTCATAGAACTTCTGAACCGTCACGTCCTGCATGCTCGCTGTCGCCTGGCTTAAACCTGTTTCAGCTGC
CTTATGACACTGTGGAGATA

Product: LuxR family transcriptional response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGIRIILADDHVMFREGMRALLEREEDMVVVAEAGDGVSVVEKTLENMPDVVVLDLSMPGMNGTEAASVIHQKVPGIGII
ILSMHSDRQYVIEALKLGVKSFILKEWAFQELVTAVRCVFKDTSYLSPRLSDIIISGLADEGKPLGKYSLTPREEQAYRL
LVAGKNCKEIGYELKISSKTVETYRLKVMKKLNISNIAQLVNHAVQEGIVGRPESF

Sequences:

>Translated_216_residues
MGIRIILADDHVMFREGMRALLEREEDMVVVAEAGDGVSVVEKTLENMPDVVVLDLSMPGMNGTEAASVIHQKVPGIGII
ILSMHSDRQYVIEALKLGVKSFILKEWAFQELVTAVRCVFKDTSYLSPRLSDIIISGLADEGKPLGKYSLTPREEQAYRL
LVAGKNCKEIGYELKISSKTVETYRLKVMKKLNISNIAQLVNHAVQEGIVGRPESF
>Mature_215_residues
GIRIILADDHVMFREGMRALLEREEDMVVVAEAGDGVSVVEKTLENMPDVVVLDLSMPGMNGTEAASVIHQKVPGIGIII
LSMHSDRQYVIEALKLGVKSFILKEWAFQELVTAVRCVFKDTSYLSPRLSDIIISGLADEGKPLGKYSLTPREEQAYRLL
VAGKNCKEIGYELKISSKTVETYRLKVMKKLNISNIAQLVNHAVQEGIVGRPESF

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=32.2115384615385, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=35.6435643564356, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788521, Length=209, Percent_Identity=30.1435406698565, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=27.4509803921569, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=27.8048780487805, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=31.3186813186813, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=23.5, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23961; Mature: 23830

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRIILADDHVMFREGMRALLEREEDMVVVAEAGDGVSVVEKTLENMPDVVVLDLSMPG
CCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCC
MNGTEAASVIHQKVPGIGIIILSMHSDRQYVIEALKLGVKSFILKEWAFQELVTAVRCVF
CCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDTSYLSPRLSDIIISGLADEGKPLGKYSLTPREEQAYRLLVAGKNCKEIGYELKISSKT
CCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEEEEECCCHHHCCEEEEECCCH
VETYRLKVMKKLNISNIAQLVNHAVQEGIVGRPESF
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GIRIILADDHVMFREGMRALLEREEDMVVVAEAGDGVSVVEKTLENMPDVVVLDLSMPG
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCC
MNGTEAASVIHQKVPGIGIIILSMHSDRQYVIEALKLGVKSFILKEWAFQELVTAVRCVF
CCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDTSYLSPRLSDIIISGLADEGKPLGKYSLTPREEQAYRLLVAGKNCKEIGYELKISSKT
CCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEEEEECCCHHHCCEEEEECCCH
VETYRLKVMKKLNISNIAQLVNHAVQEGIVGRPESF
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA