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The map label for this gene is exuT [H]

Identifier: 197118596

GI number: 197118596

Start: 2576074

End: 2577315

Strand: Reverse

Name: exuT [H]

Synonym: Gbem_2215

Alternate gene names: 197118596

Gene position: 2577315-2576074 (Counterclockwise)

Preceding gene: 197118597

Following gene: 197118595

Centisome position: 55.84

GC content: 65.22

Gene sequence:

>1242_bases
ATGCAGGCAGAACAGATCCCTCTTTCCTACCGAAGATACGCGCTGGGACTGCTCCTGGCGGTCAACCTGCTCAACTACAT
CGACCGGCAGGTCCTCTTCGCGGTATTCCCCCTGATCAAGGCGGACCTCAACATCAGCGATACCGAACTGGGGCTTCTCG
GTAGCGCCTTCATGCTGAGCTACATGGTCATCGCCCCAGTCTTCGGCTGGCTTGGGGACCACTGGGACCGGGTCAAGCTT
GCCTCGTCCGGCGTCGTCGTCTGGAGCCTGGCCACCGTACTCGCCGGCTTTGCGCCCGGCTACCGCACGCTTCTTTCGGC
GCGGGCCACCGTCGGGGTAGGGGAGGCAAGCTTCGGAACCGTGTCCCCTGGGCTCATTGCCGACTTCTTCCCGAAGGATC
AGCGCGGCCGCATCCTTTCCTGGTTTTACGTGGCTATTCCCGTGGGGAGCGCCATGGGTTACCTCCTGGGGGGTGTCCTG
GGGCACCGTTTCGGCTGGCATGCCGCCTTCCTCATGGTGGGCCTGCCGGGCATGCTCCTGGCGCTGCCGCTTTGGTTTTT
GCGCACCCCGGAGCGCGGGGGGGACCGCTCGAGCGAGGAGGTCGCCGAGGAGAAGGGGATGGCTGGCTACCTCCAGCTCT
TCAGAAACCGCGCCTTCGTCACCAACACCCTTGCCATGGCCGCCATGACCTTCGCCATAGGGGGGCTGGCGCAGTGGATC
CCCACCTTCCTGTTCCGGGTGCATGCCCAGGACGTCGAGAAGGCGAACACGCTCTTCGGGTCCACCACCGTGCTGGCTGG
GATACTGGGGACCCTGGCCGGCGGGTGGCTCGGGGACCGCTGGCAGAAAAAGAGCAGCAAGGGGTACCTACTCGTATCGG
GATGGGGCTTCTTCATCGGCGCCCCTTTCGCCGCCTGGGCCATCATGGCGCCGGCGCTACCGGTCTGCATGGCCGCCATC
TTCGTGGCCGAGTTTTTCCTCTTCCTTAACACCGGGCCGCTCAACACGGTGATCATCAACGTGACGCGCCCTGCCGTGCG
CGCCATGGCTTTCGCGGTGAACATCTTCTTCATCCACGCCCTGGGGGACGCCGTCTCGCCGTCGATGCTCGGTTGGCTCT
CCGACCAGTGTGGGCTGAGGCTCGCGCTTCTCTCCACGCCGCTGGTGATGGCGCTGGCCGGGGTGCTTTGCTTCGTCTGC
GGCAGGTATGTGGCGCACGACATGGCGCAGGCCGAGCCCTGA

Upstream 100 bases:

>100_bases
AAAGCGCACGCGGCCGTGGCTGCGCTATAAACCACTCGCCTGCCGGGGCGCCGGCCCCGGATGTTATGCAAGTCATGGAA
GTTATGGAGGATGAAAACGG

Downstream 100 bases:

>100_bases
TACTGACTGGAGGTTTGCATGTCCTTTTTCGTCCGAAATCTTTTACTATCCCTACTGTTGCTGCCGGCGCTTCTCTCCGG
CTGCGCCACTGCCCAAAAAC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MQAEQIPLSYRRYALGLLLAVNLLNYIDRQVLFAVFPLIKADLNISDTELGLLGSAFMLSYMVIAPVFGWLGDHWDRVKL
ASSGVVVWSLATVLAGFAPGYRTLLSARATVGVGEASFGTVSPGLIADFFPKDQRGRILSWFYVAIPVGSAMGYLLGGVL
GHRFGWHAAFLMVGLPGMLLALPLWFLRTPERGGDRSSEEVAEEKGMAGYLQLFRNRAFVTNTLAMAAMTFAIGGLAQWI
PTFLFRVHAQDVEKANTLFGSTTVLAGILGTLAGGWLGDRWQKKSSKGYLLVSGWGFFIGAPFAAWAIMAPALPVCMAAI
FVAEFFLFLNTGPLNTVIINVTRPAVRAMAFAVNIFFIHALGDAVSPSMLGWLSDQCGLRLALLSTPLVMALAGVLCFVC
GRYVAHDMAQAEP

Sequences:

>Translated_413_residues
MQAEQIPLSYRRYALGLLLAVNLLNYIDRQVLFAVFPLIKADLNISDTELGLLGSAFMLSYMVIAPVFGWLGDHWDRVKL
ASSGVVVWSLATVLAGFAPGYRTLLSARATVGVGEASFGTVSPGLIADFFPKDQRGRILSWFYVAIPVGSAMGYLLGGVL
GHRFGWHAAFLMVGLPGMLLALPLWFLRTPERGGDRSSEEVAEEKGMAGYLQLFRNRAFVTNTLAMAAMTFAIGGLAQWI
PTFLFRVHAQDVEKANTLFGSTTVLAGILGTLAGGWLGDRWQKKSSKGYLLVSGWGFFIGAPFAAWAIMAPALPVCMAAI
FVAEFFLFLNTGPLNTVIINVTRPAVRAMAFAVNIFFIHALGDAVSPSMLGWLSDQCGLRLALLSTPLVMALAGVLCFVC
GRYVAHDMAQAEP
>Mature_413_residues
MQAEQIPLSYRRYALGLLLAVNLLNYIDRQVLFAVFPLIKADLNISDTELGLLGSAFMLSYMVIAPVFGWLGDHWDRVKL
ASSGVVVWSLATVLAGFAPGYRTLLSARATVGVGEASFGTVSPGLIADFFPKDQRGRILSWFYVAIPVGSAMGYLLGGVL
GHRFGWHAAFLMVGLPGMLLALPLWFLRTPERGGDRSSEEVAEEKGMAGYLQLFRNRAFVTNTLAMAAMTFAIGGLAQWI
PTFLFRVHAQDVEKANTLFGSTTVLAGILGTLAGGWLGDRWQKKSSKGYLLVSGWGFFIGAPFAAWAIMAPALPVCMAAI
FVAEFFLFLNTGPLNTVIINVTRPAVRAMAFAVNIFFIHALGDAVSPSMLGWLSDQCGLRLALLSTPLVMALAGVLCFVC
GRYVAHDMAQAEP

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=392, Percent_Identity=37.2448979591837, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI14042968, Length=392, Percent_Identity=37.2448979591837, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI185136021, Length=427, Percent_Identity=33.7236533957845, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI215490100, Length=371, Percent_Identity=36.3881401617251, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI215490102, Length=377, Percent_Identity=34.4827586206897, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI194239645, Length=437, Percent_Identity=30.2059496567506, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI215490098, Length=377, Percent_Identity=32.8912466843501, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI2367379, Length=332, Percent_Identity=25.3012048192771, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082320, Length=298, Percent_Identity=24.8322147651007, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082404, Length=266, Percent_Identity=24.4360902255639, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI2367193, Length=292, Percent_Identity=26.3698630136986, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787947, Length=262, Percent_Identity=25.5725190839695, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789515, Length=302, Percent_Identity=24.5033112582781, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71992409, Length=434, Percent_Identity=30.184331797235, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193209775, Length=462, Percent_Identity=27.9220779220779, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17557872, Length=389, Percent_Identity=30.3341902313625, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17539092, Length=394, Percent_Identity=29.9492385786802, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24654041, Length=373, Percent_Identity=32.7077747989276, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24654037, Length=373, Percent_Identity=32.7077747989276, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17864456, Length=373, Percent_Identity=32.4396782841823, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24654039, Length=373, Percent_Identity=32.4396782841823, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24654044, Length=234, Percent_Identity=35.042735042735, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44616; Mature: 44616

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]