Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 197118582

GI number: 197118582

Start: 2560662

End: 2561891

Strand: Reverse

Name: macB [H]

Synonym: Gbem_2201

Alternate gene names: 197118582

Gene position: 2561891-2560662 (Counterclockwise)

Preceding gene: 197118583

Following gene: 197118581

Centisome position: 55.51

GC content: 63.74

Gene sequence:

>1230_bases
ATGAGCACCCTCTACCAGAGTTTCCTGATAGCTGTGCGCGCGCTCAGGGTGAACAAGATGCGTGCGCTGTTGACCATGCT
GGGGATCATCATCGGCATCGCCGCGGTCATCGCCATGGTGGCCATCGGCGCGGGCGCGAGCAAGATGATCTCCGACCAGA
TCTCCAGCATCGGGTCGAACCTGCTCCTGGTGCTCCCCGGCTCCACCACCAGCGGGGGGTTGCGCTCCGGCGCCGGGTCC
AACCAGACGCTCACCTACGACGACGCCATGGCCATCAAGGCCGAATGCCCGTCGGTGGGAGCGGTGGCGCCGCAGGTGCG
CGGCTCGGGGCAGGTGGTCTACGGCAACCAGAACTGGTCCACCGTCGTCTACGGCGTGACGCCGGACGTGATCCAGGTGC
GCGACTGGACCATCACGGCCGGGCGCAACATCACCCAGTCCGATGTCGACGGCGCCACCAAGAGCTGCCTGATCGGGCAG
ACCGTCGCCGACAACCTCTTCGGAGCGGCCGATCCAATCGGGAAGATCATCAGGATCAAGAAGATACCCTTCACTGTAGT
AGGGCTTTTGGGCCAAAAGGGGCAGTCCCCTCAAGGGCAGGATCAGGACGACGTCATCTACGTGCCGCTTCGGACCGCGC
AGCGAAAGCTATTGGGTAGCCAGTTCCCGAACGTGGTCGGCTCCATCATGGTACAGGCCAAAAGCGGCGAGGTGCTGGAT
CAGGCCGAGGAGGAGGTGACGGCGCTCTTGAACCAAAGGCACCGCATCGGCCCCAGCCGCGAGGTCGACTTCACCATCAG
GAACCTCTCCGAGCTCCTGGCTCTCACCGCCCAGTCCTCGAAGGTCATGTCGATTCTCCTGGGGGCGGTCGCCTCCATCT
CCCTCGTGGTAGGCGGGATCGGCATCATGAACATCATGCTGGTGTCGGTCACCGAGAGGACCCGCGAGATCGGGATCCGG
ATCGCCATCGGCGCCAAGAGGCGCGACATACTGCTGCAGTTTCTCACCGAGGCGGTGCTCCTCACCACCTGCGGCGGCAT
CATCGGCATGCTGCTCGGCGTCGCGGGGGCGCGGCTGGTCGCCTCTCTGGTGGGGTGGCCTACGCTGGTATCGGTGAACA
CCATCGTCATCGCCTTTGCCTTTTCCGCCGGGGTCGGGGTCTTCTTCGGGTTCTATCCGGCCCGCAAAGCGTCCTCTTTG
AACCCAATAGAAGCGCTGAGATACGAATAA

Upstream 100 bases:

>100_bases
AATTCACCGGGAGGCACATCATCTTTCGCGACGGCCTGATCGTTTCCGACACCCCTCATGCCGCGAAGAGCGCGACCGTA
CCGGGGGAGGTGGCCAGGCC

Downstream 100 bases:

>100_bases
AAGCTAACCGCTGCTTGAAAGGATCGTAGCCATGAAGATAACCGCCAAAACGACCGCCGTTGCCGCCCTTTGCCTGCTCC
TTGGTATGGCCGGCTCCGGA

Product: ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSTLYQSFLIAVRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSNLLLVLPGSTTSGGLRSGAGS
NQTLTYDDAMAIKAECPSVGAVAPQVRGSGQVVYGNQNWSTVVYGVTPDVIQVRDWTITAGRNITQSDVDGATKSCLIGQ
TVADNLFGAADPIGKIIRIKKIPFTVVGLLGQKGQSPQGQDQDDVIYVPLRTAQRKLLGSQFPNVVGSIMVQAKSGEVLD
QAEEEVTALLNQRHRIGPSREVDFTIRNLSELLALTAQSSKVMSILLGAVASISLVVGGIGIMNIMLVSVTERTREIGIR
IAIGAKRRDILLQFLTEAVLLTTCGGIIGMLLGVAGARLVASLVGWPTLVSVNTIVIAFAFSAGVGVFFGFYPARKASSL
NPIEALRYE

Sequences:

>Translated_409_residues
MSTLYQSFLIAVRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSNLLLVLPGSTTSGGLRSGAGS
NQTLTYDDAMAIKAECPSVGAVAPQVRGSGQVVYGNQNWSTVVYGVTPDVIQVRDWTITAGRNITQSDVDGATKSCLIGQ
TVADNLFGAADPIGKIIRIKKIPFTVVGLLGQKGQSPQGQDQDDVIYVPLRTAQRKLLGSQFPNVVGSIMVQAKSGEVLD
QAEEEVTALLNQRHRIGPSREVDFTIRNLSELLALTAQSSKVMSILLGAVASISLVVGGIGIMNIMLVSVTERTREIGIR
IAIGAKRRDILLQFLTEAVLLTTCGGIIGMLLGVAGARLVASLVGWPTLVSVNTIVIAFAFSAGVGVFFGFYPARKASSL
NPIEALRYE
>Mature_408_residues
STLYQSFLIAVRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSNLLLVLPGSTTSGGLRSGAGSN
QTLTYDDAMAIKAECPSVGAVAPQVRGSGQVVYGNQNWSTVVYGVTPDVIQVRDWTITAGRNITQSDVDGATKSCLIGQT
VADNLFGAADPIGKIIRIKKIPFTVVGLLGQKGQSPQGQDQDDVIYVPLRTAQRKLLGSQFPNVVGSIMVQAKSGEVLDQ
AEEEVTALLNQRHRIGPSREVDFTIRNLSELLALTAQSSKVMSILLGAVASISLVVGGIGIMNIMLVSVTERTREIGIRI
AIGAKRRDILLQFLTEAVLLTTCGGIIGMLLGVAGARLVASLVGWPTLVSVNTIVIAFAFSAGVGVFFGFYPARKASSLN
PIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=411, Percent_Identity=37.712895377129, Blast_Score=226, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43070; Mature: 42939

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYQSFLIAVRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LLLVLPGSTTSGGLRSGAGSNQTLTYDDAMAIKAECPSVGAVAPQVRGSGQVVYGNQNWS
EEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCC
TVVYGVTPDVIQVRDWTITAGRNITQSDVDGATKSCLIGQTVADNLFGAADPIGKIIRIK
EEEEECCCCEEEEEEEEEECCCCCCCHHCCCCHHHHHCCHHHHHHHCCCCCCHHHHEEEE
KIPFTVVGLLGQKGQSPQGQDQDDVIYVPLRTAQRKLLGSQFPNVVGSIMVQAKSGEVLD
CCCHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCHHHHHHHEEEECCCCHHH
QAEEEVTALLNQRHRIGPSREVDFTIRNLSELLALTAQSSKVMSILLGAVASISLVVGGI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GIMNIMLVSVTERTREIGIRIAIGAKRRDILLQFLTEAVLLTTCGGIIGMLLGVAGARLV
HHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLVGWPTLVSVNTIVIAFAFSAGVGVFFGFYPARKASSLNPIEALRYE
HHHHCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
STLYQSFLIAVRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LLLVLPGSTTSGGLRSGAGSNQTLTYDDAMAIKAECPSVGAVAPQVRGSGQVVYGNQNWS
EEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCC
TVVYGVTPDVIQVRDWTITAGRNITQSDVDGATKSCLIGQTVADNLFGAADPIGKIIRIK
EEEEECCCCEEEEEEEEEECCCCCCCHHCCCCHHHHHCCHHHHHHHCCCCCCHHHHEEEE
KIPFTVVGLLGQKGQSPQGQDQDDVIYVPLRTAQRKLLGSQFPNVVGSIMVQAKSGEVLD
CCCHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCHHHHHHHEEEECCCCHHH
QAEEEVTALLNQRHRIGPSREVDFTIRNLSELLALTAQSSKVMSILLGAVASISLVVGGI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GIMNIMLVSVTERTREIGIRIAIGAKRRDILLQFLTEAVLLTTCGGIIGMLLGVAGARLV
HHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLVGWPTLVSVNTIVIAFAFSAGVGVFFGFYPARKASSLNPIEALRYE
HHHHCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA