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The map label for this gene is fadR [H]

Identifier: 197118512

GI number: 197118512

Start: 2477562

End: 2478263

Strand: Reverse

Name: fadR [H]

Synonym: Gbem_2130

Alternate gene names: 197118512

Gene position: 2478263-2477562 (Counterclockwise)

Preceding gene: 308535285

Following gene: 197118506

Centisome position: 53.7

GC content: 62.82

Gene sequence:

>702_bases
ATGAGGAAGACCTACCAGATGGTGGAGAAGGCATTGGTGGCGAGGTTGCTCAAGGGGGATCCGAAACCGGGCTGCACCCT
GGAGAGCGAGCGGGATCTCGCGCAAAGCTTTTCGGTGAGCCGGGCCACGGTGAGGGAGGCCCTGCAGAAACTGCAGAATT
CGGGATGGATCTCGGTGCAGCAGCGACATTGTACGGTGGTGAACGATTTCTGGTCCCAGGGGGACCTGGAGCTCATCTCC
TCCATCACCCGTAACAGCGAGGATTTTCCGCCCGACCTGGCGTCCCACCTCCTGGAGTTGCGGGTCCAGTTCGCGCCCGA
CTACGCGAGAAGGGCCGTCGAGAACAACGCTGCGGGGCTTGCCGAGATCCTGGCGCGGGCCGATAAGGTCCGCAACTGCG
CCGGCTCCCTGGTGAAATACGACTGGGAACTGCACATGGCCATGGCGGTGATGTCGGGGAACAGGATCTACCCGCTGATC
CTGAACAGCTTTTCCAGCGTCTACTCCAAGCTGCGCACCGCCCTCTTCACCAAGGAGGAATACCGGCTCCAGGCGCGGAA
GTACTACCGGGAGATGCTGCAGGCAGCGAGCACCGGCAATGCGATCCTCGCGGAAAGCATCACGAGGGGCGCGATGAAGC
TGAGGCTCGACTCCTTCCAGATCCAGTTCGGCGGGATGCAGGGGCTGCCGGCGCCGGCCTGA

Upstream 100 bases:

>100_bases
CATTTTACCAAACCTTGTTCTATGATATCGCAATAGTTGCAGTAAGCCCCGGTCCGCACAATACAGACAACTGCCTTCAG
TGATCGATAGAGGGAATTTT

Downstream 100 bases:

>100_bases
CTCAGGGGCAGAGGGTGAAGCAGATAGTCGCGCCGTTGCCGACCTCGGCCTCGGCCCAGATCCTCCCGCCATGGCGGTGC
ACGATGCGCTGCGCCGTGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRKTYQMVEKALVARLLKGDPKPGCTLESERDLAQSFSVSRATVREALQKLQNSGWISVQQRHCTVVNDFWSQGDLELIS
SITRNSEDFPPDLASHLLELRVQFAPDYARRAVENNAAGLAEILARADKVRNCAGSLVKYDWELHMAMAVMSGNRIYPLI
LNSFSSVYSKLRTALFTKEEYRLQARKYYREMLQAASTGNAILAESITRGAMKLRLDSFQIQFGGMQGLPAPA

Sequences:

>Translated_233_residues
MRKTYQMVEKALVARLLKGDPKPGCTLESERDLAQSFSVSRATVREALQKLQNSGWISVQQRHCTVVNDFWSQGDLELIS
SITRNSEDFPPDLASHLLELRVQFAPDYARRAVENNAAGLAEILARADKVRNCAGSLVKYDWELHMAMAVMSGNRIYPLI
LNSFSSVYSKLRTALFTKEEYRLQARKYYREMLQAASTGNAILAESITRGAMKLRLDSFQIQFGGMQGLPAPA
>Mature_233_residues
MRKTYQMVEKALVARLLKGDPKPGCTLESERDLAQSFSVSRATVREALQKLQNSGWISVQQRHCTVVNDFWSQGDLELIS
SITRNSEDFPPDLASHLLELRVQFAPDYARRAVENNAAGLAEILARADKVRNCAGSLVKYDWELHMAMAVMSGNRIYPLI
LNSFSSVYSKLRTALFTKEEYRLQARKYYREMLQAASTGNAILAESITRGAMKLRLDSFQIQFGGMQGLPAPA

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=193, Percent_Identity=29.5336787564767, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26182; Mature: 26182

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50949 HTH_GNTR ; PS00527 RIBOSOMAL_S14

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTYQMVEKALVARLLKGDPKPGCTLESERDLAQSFSVSRATVREALQKLQNSGWISVQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
QRHCTVVNDFWSQGDLELISSITRNSEDFPPDLASHLLELRVQFAPDYARRAVENNAAGL
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHH
AEILARADKVRNCAGSLVKYDWELHMAMAVMSGNRIYPLILNSFSSVYSKLRTALFTKEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YRLQARKYYREMLQAASTGNAILAESITRGAMKLRLDSFQIQFGGMQGLPAPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MRKTYQMVEKALVARLLKGDPKPGCTLESERDLAQSFSVSRATVREALQKLQNSGWISVQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
QRHCTVVNDFWSQGDLELISSITRNSEDFPPDLASHLLELRVQFAPDYARRAVENNAAGL
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHH
AEILARADKVRNCAGSLVKYDWELHMAMAVMSGNRIYPLILNSFSSVYSKLRTALFTKEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YRLQARKYYREMLQAASTGNAILAESITRGAMKLRLDSFQIQFGGMQGLPAPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA