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The map label for this gene is aphA [H]

Identifier: 197118497

GI number: 197118497

Start: 2452401

End: 2453540

Strand: Direct

Name: aphA [H]

Synonym: Gbem_2115

Alternate gene names: 197118497

Gene position: 2452401-2453540 (Clockwise)

Preceding gene: 197118496

Following gene: 197118498

Centisome position: 53.14

GC content: 63.07

Gene sequence:

>1140_bases
ATGGAGATGGAACTCGCCGAGCGGCTTTACCGACTGATGTTCACCAACATGCGGGAAGGGCTGGCCATCCTGCGCATCGA
CCCCGACGATGGCGATGGATCCCCGGAGGTGATCGAGATGAACCCCGCCGCTGTGAAACTCTGCCGTTGCCGCCCGTTCA
ACTGCAAGGTCGTCGACTGTTTCCCCGGCTGGTTCGACGAGGACCGGCTTCAGGAAACCTGCAAACGCCTGGTGGCGTTC
GGCGGCATGGTGGAACTGGGCGAGGTCTCCTGGGGAGGGTCCAGTTACCGCGCCCGTATCTTCGGGTTGTCGGAGGAACA
CTTGGGGCTCGTCGTCGACGACGTAACGCGCCAGAAGAGGGGGGAGGCGGAGATAGCAACGCTTTCGGCCCGGATCGAGC
AGCAGACGGCGGGGCTGGAAAAGCGCGTGGCGGAGAGGACCGCGCAGTTGCAGGAAATCAACGAGGAACTCGACAGCTTC
GCCTACTCGGTTTCCCATGACTTGCGCGCGCCGCTGCGCGCCATGCGGGCCTTCGCCGGAATACTGCTGGAGGAGGAGCA
AAGCGAGGACGAGCGGATAGCGTACCTGAAACGGATCCAGGGGGCGGCGGAGGGTATGGAGCGCCTGATCCAGGATCTCC
TCGCCTACAGCCGGGTCGGCCGCCAGGAATTGGTGCTGCAGCGCGTAAGCCTCGATGAGGTGCTTGCCGACGCGGCCAAG
CAATTGGAGCTTACCAGCGGGGGCAAGAGCTACCGCTTGGACGTGCGGGACCATCTCCCCGATGTGGTCGGGCACCATAC
GGTGCTGGTCCAGGTGGTTTTGAACATCATGGGGAACGCCATAAAGTTCGTTCCCAAAGGGGTGGTCCCGGCGCTGGAGG
TGTGGGCCGAAGATATAGACGGGGAGTGCCGCCTTAACATCGCCGACAACGGCATCGGCATTGCGCCTGAGCACCAGGAG
CGGATCTTCAAGATCTTCGAGCGGCTGCACGGCATAGAAAGCTACGCCGGCACAGGAATCGGGCTAGCCATCGCGCGCAA
GGCGGTGACCAGGCTTGGGGGAAGGATAGGGGTGGAGTCCCGGGAAGGGGAAGGGAGCAGGTTCTGGATCGAGCTTAAAA
AAGCCGGGCCCGCGTCATGA

Upstream 100 bases:

>100_bases
ACCTCCCAATTTTATGCCTCTGGAACCCAGATTTAATATTAGTGCAAATTAATATTCCTTCGCTATACTCTTCTGCATTT
CGCGGAAAAGGACCTCTGTC

Downstream 100 bases:

>100_bases
GGGCCGAACTCGCCAGGAAGGCTGTATGAGCTACGTGCACCATACCATACTGTTGGTGGACAGCGACCAGGATATGGCCC
ACTTCGCCATGCTCGCGCTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MEMELAERLYRLMFTNMREGLAILRIDPDDGDGSPEVIEMNPAAVKLCRCRPFNCKVVDCFPGWFDEDRLQETCKRLVAF
GGMVELGEVSWGGSSYRARIFGLSEEHLGLVVDDVTRQKRGEAEIATLSARIEQQTAGLEKRVAERTAQLQEINEELDSF
AYSVSHDLRAPLRAMRAFAGILLEEEQSEDERIAYLKRIQGAAEGMERLIQDLLAYSRVGRQELVLQRVSLDEVLADAAK
QLELTSGGKSYRLDVRDHLPDVVGHHTVLVQVVLNIMGNAIKFVPKGVVPALEVWAEDIDGECRLNIADNGIGIAPEHQE
RIFKIFERLHGIESYAGTGIGLAIARKAVTRLGGRIGVESREGEGSRFWIELKKAGPAS

Sequences:

>Translated_379_residues
MEMELAERLYRLMFTNMREGLAILRIDPDDGDGSPEVIEMNPAAVKLCRCRPFNCKVVDCFPGWFDEDRLQETCKRLVAF
GGMVELGEVSWGGSSYRARIFGLSEEHLGLVVDDVTRQKRGEAEIATLSARIEQQTAGLEKRVAERTAQLQEINEELDSF
AYSVSHDLRAPLRAMRAFAGILLEEEQSEDERIAYLKRIQGAAEGMERLIQDLLAYSRVGRQELVLQRVSLDEVLADAAK
QLELTSGGKSYRLDVRDHLPDVVGHHTVLVQVVLNIMGNAIKFVPKGVVPALEVWAEDIDGECRLNIADNGIGIAPEHQE
RIFKIFERLHGIESYAGTGIGLAIARKAVTRLGGRIGVESREGEGSRFWIELKKAGPAS
>Mature_379_residues
MEMELAERLYRLMFTNMREGLAILRIDPDDGDGSPEVIEMNPAAVKLCRCRPFNCKVVDCFPGWFDEDRLQETCKRLVAF
GGMVELGEVSWGGSSYRARIFGLSEEHLGLVVDDVTRQKRGEAEIATLSARIEQQTAGLEKRVAERTAQLQEINEELDSF
AYSVSHDLRAPLRAMRAFAGILLEEEQSEDERIAYLKRIQGAAEGMERLIQDLLAYSRVGRQELVLQRVSLDEVLADAAK
QLELTSGGKSYRLDVRDHLPDVVGHHTVLVQVVLNIMGNAIKFVPKGVVPALEVWAEDIDGECRLNIADNGIGIAPEHQE
RIFKIFERLHGIESYAGTGIGLAIARKAVTRLGGRIGVESREGEGSRFWIELKKAGPAS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=31.0756972111554, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=222, Percent_Identity=30.6306306306306, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=26.8398268398268, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788713, Length=223, Percent_Identity=23.3183856502242, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=350, Percent_Identity=25.4285714285714, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=296, Percent_Identity=26.3513513513513, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=27.1317829457364, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=214, Percent_Identity=28.5046728971963, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=264, Percent_Identity=28.030303030303, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=28.75, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786783, Length=256, Percent_Identity=24.609375, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=265, Percent_Identity=26.0377358490566, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=26.5700483091787, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=26.0330578512397, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42202; Mature: 42202

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMELAERLYRLMFTNMREGLAILRIDPDDGDGSPEVIEMNPAAVKLCRCRPFNCKVVDC
CCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECHHHHHHHCCCCCCCEEEEC
FPGWFDEDRLQETCKRLVAFGGMVELGEVSWGGSSYRARIFGLSEEHLGLVVDDVTRQKR
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCHHHCCEEHHHHHHHHC
GEAEIATLSARIEQQTAGLEKRVAERTAQLQEINEELDSFAYSVSHDLRAPLRAMRAFAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLEEEQSEDERIAYLKRIQGAAEGMERLIQDLLAYSRVGRQELVLQRVSLDEVLADAAK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QLELTSGGKSYRLDVRDHLPDVVGHHTVLVQVVLNIMGNAIKFVPKGVVPALEVWAEDID
HEEECCCCCEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
GECRLNIADNGIGIAPEHQERIFKIFERLHGIESYAGTGIGLAIARKAVTRLGGRIGVES
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
REGEGSRFWIELKKAGPAS
CCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MEMELAERLYRLMFTNMREGLAILRIDPDDGDGSPEVIEMNPAAVKLCRCRPFNCKVVDC
CCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEECHHHHHHHCCCCCCCEEEEC
FPGWFDEDRLQETCKRLVAFGGMVELGEVSWGGSSYRARIFGLSEEHLGLVVDDVTRQKR
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCHHHCCEEHHHHHHHHC
GEAEIATLSARIEQQTAGLEKRVAERTAQLQEINEELDSFAYSVSHDLRAPLRAMRAFAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLEEEQSEDERIAYLKRIQGAAEGMERLIQDLLAYSRVGRQELVLQRVSLDEVLADAAK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QLELTSGGKSYRLDVRDHLPDVVGHHTVLVQVVLNIMGNAIKFVPKGVVPALEVWAEDID
HEEECCCCCEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
GECRLNIADNGIGIAPEHQERIFKIFERLHGIESYAGTGIGLAIARKAVTRLGGRIGVES
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
REGEGSRFWIELKKAGPAS
CCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]