Click here to switch to the map view.

The map label for this gene is fabD-3 [H]

Identifier: 197118488

GI number: 197118488

Start: 2443629

End: 2445293

Strand: Reverse

Name: fabD-3 [H]

Synonym: Gbem_2106

Alternate gene names: 197118488

Gene position: 2445293-2443629 (Counterclockwise)

Preceding gene: 197118489

Following gene: 197118487

Centisome position: 52.98

GC content: 66.61

Gene sequence:

>1665_bases
TTGGATCCATTTTCACTACAGGGTGACCATACCGCTCGCTCTGCAAACCTGGAAAACCTGGGTTCGTGGCACCCCGCCTC
GAACGCCCCCCCTCAAAAGGCCGCCAACCTGAGAGACGCCCTCCGCTACGTACGCCAGCCGCTGTATCTCGTGGAAAAGG
AAAGGACCATGGTCCCGAGGCTGGGAGGGATCGGCCGGCTCGGCGCCGTCAACCCGGGCGCGCTGCCTATCGCCGCTTAC
GCCCCTCCCTGCTTTCCGGAAAACCTGGGGGATCCTTCTTTTTGCCGCGAACTTGGCATCCGCTACCCCTACGTCGGCGG
TTCCATGGCCAAGGGGATCAGTTCCGCGGCCATGGCCGAGGAGTTGGGCCGCGCCGGGATGCTCGGCTTCTTCGGCGCCG
CCGGCCTTCCGCTTGCCACCGTCTCCGAGACCGCCGACCGCCTCAAGGCCTCCCTCGGCGATATCCCCTACGGTTTCAAC
CTGATCCACTCCCCGCACGAGCCCGAGTTGGAGCGCGAGCTCGCCGAGCTGTACATAAAGAAGGGGATCCGCACAATCGA
GGCCTCGGCCTTCCTGGCCCTGACGCTACCCTTGGTCAGGTACCGGCTGCACGGCATCAAGCGCGCCGCCGACGGGTCCA
TCGTCACCCCCAACCGCATCATCGCCAAGGTCTCCCGCGAGGAACTGGCGGCGAAGTTCTTCGCACCGGCTCCCGAGAAG
CTCCTGCGCGCGCTGGTCGCCAACGGCTCCATCACCGCCGAGCAGGCCGAACTGGCCGCGCTGGTACCGCTGGCGCAGGA
CGTGACGGCCGAGGCTGATTCCGGCGGCCATACCGACAACCGCCCCGCCCTCGCCCTCTTCCCGACCATCAACGCGCTGG
CGGCGAAGCTGCAGCGGCAGTACGGCTACAGCTGCCGCCTGCGGGTGGGGCTTGGCGGCGGAGTCTCGACGCCGGCCTCA
GCGGCAGCCGCCTTCTCCATGGGCGCCGCCTACCTCGTGACCGGGTCGGTGAATCAGGCCTGCGTCGAGTCCGGCACCTC
CGACACCGTGCGCGGCATGCTCGCCGGCACCCGCCAGGCTGACGTGACCATGGCCCCCGCCGCCGACATGTTCGAGATGG
GGGTCACCGTGCAGGTCCTAAAGCGCGGCACCATGTTCCCCATGCGCGCACAGAAGCTCTACGAGATCTACCGCGCCTGC
AGCAGCCTCGACGACATCCCCGCCGCCGAGCGCGAGAAGCTGGAGAAGACCATGTTCCAGGCGTCGCTCGCCGACATCTG
GCACGACACCCGCGCCTTCTTCGCCAAGCGCGACCCCTCCCAGGTCGAGCGTGCCGAGCGCGACCCGAAGCACCTGATGG
CGTTGGTCTTCCGCTGGTATCTCGGCATGGCCGCGCACTGGGCCAAAGACGGAGCGGAAGAGCGGCGCATGGACTACCAG
GTCTGGTGCGGCCCCGCCATGGGAGCCTTCAACGAATGGGCCTCAGGTTCCTTCCTCGACGCCCCGGGCAATCGCACGGT
CGAAGCCGTGGCCCTAAACATCCTGCACGGAGCGGCCGCACTTAACCGCGCCAACTTCCTGAGCAGCCAGGGCATCGAAC
TCAGGATGGATGAAATCGCACCGCAACCTCTCGAAATCGCACAAATCAAGGAGTACCTTTGTTGA

Upstream 100 bases:

>100_bases
ACCTGCCTCCTCCATGCCCAAGCTTGTCCTTCTGCCGAATCACACTCGTTTAGGCCATCGCAATTCCGCTGCTAATTTGC
TGGCAGCAGGAGAAGCCCGT

Downstream 100 bases:

>100_bases
AAACTGACGATCTGAAGCCGGCCGCCTCTAGTAACGGAACTCAGCTTGCCATCATCGGCATCGGTTGCCTTTTTCCCAAG
GCCGAGGACCGTGACGCCTA

Product: malonyl-CoA--acyl carrier protein transacylase

Products: NA

Alternate protein names: Malonyl CoA-acyl carrier protein transacylase; MCT [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MDPFSLQGDHTARSANLENLGSWHPASNAPPQKAANLRDALRYVRQPLYLVEKERTMVPRLGGIGRLGAVNPGALPIAAY
APPCFPENLGDPSFCRELGIRYPYVGGSMAKGISSAAMAEELGRAGMLGFFGAAGLPLATVSETADRLKASLGDIPYGFN
LIHSPHEPELERELAELYIKKGIRTIEASAFLALTLPLVRYRLHGIKRAADGSIVTPNRIIAKVSREELAAKFFAPAPEK
LLRALVANGSITAEQAELAALVPLAQDVTAEADSGGHTDNRPALALFPTINALAAKLQRQYGYSCRLRVGLGGGVSTPAS
AAAAFSMGAAYLVTGSVNQACVESGTSDTVRGMLAGTRQADVTMAPAADMFEMGVTVQVLKRGTMFPMRAQKLYEIYRAC
SSLDDIPAAEREKLEKTMFQASLADIWHDTRAFFAKRDPSQVERAERDPKHLMALVFRWYLGMAAHWAKDGAEERRMDYQ
VWCGPAMGAFNEWASGSFLDAPGNRTVEAVALNILHGAAALNRANFLSSQGIELRMDEIAPQPLEIAQIKEYLC

Sequences:

>Translated_554_residues
MDPFSLQGDHTARSANLENLGSWHPASNAPPQKAANLRDALRYVRQPLYLVEKERTMVPRLGGIGRLGAVNPGALPIAAY
APPCFPENLGDPSFCRELGIRYPYVGGSMAKGISSAAMAEELGRAGMLGFFGAAGLPLATVSETADRLKASLGDIPYGFN
LIHSPHEPELERELAELYIKKGIRTIEASAFLALTLPLVRYRLHGIKRAADGSIVTPNRIIAKVSREELAAKFFAPAPEK
LLRALVANGSITAEQAELAALVPLAQDVTAEADSGGHTDNRPALALFPTINALAAKLQRQYGYSCRLRVGLGGGVSTPAS
AAAAFSMGAAYLVTGSVNQACVESGTSDTVRGMLAGTRQADVTMAPAADMFEMGVTVQVLKRGTMFPMRAQKLYEIYRAC
SSLDDIPAAEREKLEKTMFQASLADIWHDTRAFFAKRDPSQVERAERDPKHLMALVFRWYLGMAAHWAKDGAEERRMDYQ
VWCGPAMGAFNEWASGSFLDAPGNRTVEAVALNILHGAAALNRANFLSSQGIELRMDEIAPQPLEIAQIKEYLC
>Mature_554_residues
MDPFSLQGDHTARSANLENLGSWHPASNAPPQKAANLRDALRYVRQPLYLVEKERTMVPRLGGIGRLGAVNPGALPIAAY
APPCFPENLGDPSFCRELGIRYPYVGGSMAKGISSAAMAEELGRAGMLGFFGAAGLPLATVSETADRLKASLGDIPYGFN
LIHSPHEPELERELAELYIKKGIRTIEASAFLALTLPLVRYRLHGIKRAADGSIVTPNRIIAKVSREELAAKFFAPAPEK
LLRALVANGSITAEQAELAALVPLAQDVTAEADSGGHTDNRPALALFPTINALAAKLQRQYGYSCRLRVGLGGGVSTPAS
AAAAFSMGAAYLVTGSVNQACVESGTSDTVRGMLAGTRQADVTMAPAADMFEMGVTVQVLKRGTMFPMRAQKLYEIYRAC
SSLDDIPAAEREKLEKTMFQASLADIWHDTRAFFAKRDPSQVERAERDPKHLMALVFRWYLGMAAHWAKDGAEERRMDYQ
VWCGPAMGAFNEWASGSFLDAPGNRTVEAVALNILHGAAALNRANFLSSQGIELRMDEIAPQPLEIAQIKEYLC

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductas

COG id: COG2070

COG function: function code R; Dioxygenases related to 2-nitropropane dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the fabD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004136
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013785
- InterPro:   IPR004410
- InterPro:   IPR016036
- InterPro:   IPR014179 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF03060 NPD [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 59833; Mature: 59833

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPFSLQGDHTARSANLENLGSWHPASNAPPQKAANLRDALRYVRQPLYLVEKERTMVPR
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
LGGIGRLGAVNPGALPIAAYAPPCFPENLGDPSFCRELGIRYPYVGGSMAKGISSAAMAE
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ELGRAGMLGFFGAAGLPLATVSETADRLKASLGDIPYGFNLIHSPHEPELERELAELYIK
HHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KGIRTIEASAFLALTLPLVRYRLHGIKRAADGSIVTPNRIIAKVSREELAAKFFAPAPEK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCHHH
LLRALVANGSITAEQAELAALVPLAQDVTAEADSGGHTDNRPALALFPTINALAAKLQRQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHH
YGYSCRLRVGLGGGVSTPASAAAAFSMGAAYLVTGSVNQACVESGTSDTVRGMLAGTRQA
CCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHCCCHHHHHHHHHCCCCC
DVTMAPAADMFEMGVTVQVLKRGTMFPMRAQKLYEIYRACSSLDDIPAAEREKLEKTMFQ
CEEECCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ASLADIWHDTRAFFAKRDPSQVERAERDPKHLMALVFRWYLGMAAHWAKDGAEERRMDYQ
HHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEE
VWCGPAMGAFNEWASGSFLDAPGNRTVEAVALNILHGAAALNRANFLSSQGIELRMDEIA
EEECCHHCCHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCC
PQPLEIAQIKEYLC
CCCHHHHHHHHHCC
>Mature Secondary Structure
MDPFSLQGDHTARSANLENLGSWHPASNAPPQKAANLRDALRYVRQPLYLVEKERTMVPR
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
LGGIGRLGAVNPGALPIAAYAPPCFPENLGDPSFCRELGIRYPYVGGSMAKGISSAAMAE
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ELGRAGMLGFFGAAGLPLATVSETADRLKASLGDIPYGFNLIHSPHEPELERELAELYIK
HHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KGIRTIEASAFLALTLPLVRYRLHGIKRAADGSIVTPNRIIAKVSREELAAKFFAPAPEK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCHHH
LLRALVANGSITAEQAELAALVPLAQDVTAEADSGGHTDNRPALALFPTINALAAKLQRQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHH
YGYSCRLRVGLGGGVSTPASAAAAFSMGAAYLVTGSVNQACVESGTSDTVRGMLAGTRQA
CCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHCCCHHHHHHHHHCCCCC
DVTMAPAADMFEMGVTVQVLKRGTMFPMRAQKLYEIYRACSSLDDIPAAEREKLEKTMFQ
CEEECCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ASLADIWHDTRAFFAKRDPSQVERAERDPKHLMALVFRWYLGMAAHWAKDGAEERRMDYQ
HHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEE
VWCGPAMGAFNEWASGSFLDAPGNRTVEAVALNILHGAAALNRANFLSSQGIELRMDEIA
EEECCHHCCHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCC
PQPLEIAQIKEYLC
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]