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The map label for this gene is efp-2 [H]

Identifier: 197118437

GI number: 197118437

Start: 2369421

End: 2369984

Strand: Reverse

Name: efp-2 [H]

Synonym: Gbem_2055

Alternate gene names: 197118437

Gene position: 2369984-2369421 (Counterclockwise)

Preceding gene: 197118438

Following gene: 197118436

Centisome position: 51.35

GC content: 57.09

Gene sequence:

>564_bases
ATGTATACTGCAGCCGATCTGAAAAAAGGGCTGAAGATCGCCATCAACGACGAACCGTACATCATCACCCACTTCGATTT
CGCGAAACCGGGCAAAGGTCAGGCGCTTTACCGGACCAAGATGAAGAACATGATCACCGGTTCCACCATGGACCGCACCT
ACCGTTCCGGCGAAACCTTCGAGCCGGCCCGCCTGGAAGACCGTGTGATGCAGTACCTGTACAAGGAAGACGATCACTAC
TGCTTCATGGACAACGACACCTTCGAGCAGATCCACATCAGCGAAGAGGCCATGGGCGACGCCAAAAACTACCTGATCGA
CAACCTCCAGGTGGACGTTCTCATCTTCAGGGAGAAGGCCATCGGCGTCGACGTCCCCAACTTCGTCAATCTCAGAGTGG
TGCAGACCGACCCCTGGGTCAAGGGTGACACCTCCGGCAGCGACTCCAAGCCCGCTACCGTCGAGACCGGCTACGTGCTC
CGCGTTCCCCCCTTCATCGAAGAGGGAGAACTGATCACCATCGACACCCGCACCGGCGAATACTCCACCAGGGTAAAGGG
GTAA

Upstream 100 bases:

>100_bases
CAAGGCATAACGGATATAAAGGACCAACGGGTTTAGCCCGCCGCCTCTCGCTGCGCGCTGGATCTTTATTTAATTTCACC
AGATAGAGAAGGAAGAGCAC

Downstream 100 bases:

>100_bases
CGCATGGGAAGCTGGCCCCTGGCCAGGCGCCGCCAGGCGCTGGTCGAGCGGGGGGCGATCTTCAGCAGGATAAGAGAGTT
TTTTCAAGAAAAGGGGTATC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 2 [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MYTAADLKKGLKIAINDEPYIITHFDFAKPGKGQALYRTKMKNMITGSTMDRTYRSGETFEPARLEDRVMQYLYKEDDHY
CFMDNDTFEQIHISEEAMGDAKNYLIDNLQVDVLIFREKAIGVDVPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVL
RVPPFIEEGELITIDTRTGEYSTRVKG

Sequences:

>Translated_187_residues
MYTAADLKKGLKIAINDEPYIITHFDFAKPGKGQALYRTKMKNMITGSTMDRTYRSGETFEPARLEDRVMQYLYKEDDHY
CFMDNDTFEQIHISEEAMGDAKNYLIDNLQVDVLIFREKAIGVDVPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVL
RVPPFIEEGELITIDTRTGEYSTRVKG
>Mature_187_residues
MYTAADLKKGLKIAINDEPYIITHFDFAKPGKGQALYRTKMKNMITGSTMDRTYRSGETFEPARLEDRVMQYLYKEDDHY
CFMDNDTFEQIHISEEAMGDAKNYLIDNLQVDVLIFREKAIGVDVPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVL
RVPPFIEEGELITIDTRTGEYSTRVKG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=185, Percent_Identity=43.2432432432432, Blast_Score=176, Evalue=7e-46,
Organism=Escherichia coli, GI87082061, Length=191, Percent_Identity=27.2251308900524, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 21339; Mature: 21339

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTAADLKKGLKIAINDEPYIITHFDFAKPGKGQALYRTKMKNMITGSTMDRTYRSGETF
CCCHHHHCCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCC
EPARLEDRVMQYLYKEDDHYCFMDNDTFEQIHISEEAMGDAKNYLIDNLQVDVLIFREKA
CCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECHHHCCCHHHHHHCCEEEEEEEEEECC
IGVDVPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVLRVPPFIEEGELITIDTRTGE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCC
YSTRVKG
CEEECCC
>Mature Secondary Structure
MYTAADLKKGLKIAINDEPYIITHFDFAKPGKGQALYRTKMKNMITGSTMDRTYRSGETF
CCCHHHHCCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCC
EPARLEDRVMQYLYKEDDHYCFMDNDTFEQIHISEEAMGDAKNYLIDNLQVDVLIFREKA
CCHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECHHHCCCHHHHHHCCEEEEEEEEEECC
IGVDVPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYVLRVPPFIEEGELITIDTRTGE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCC
YSTRVKG
CEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA