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The map label for this gene is glk [H]

Identifier: 197118384

GI number: 197118384

Start: 2306855

End: 2307838

Strand: Direct

Name: glk [H]

Synonym: Gbem_2002

Alternate gene names: 197118384

Gene position: 2306855-2307838 (Clockwise)

Preceding gene: 197118383

Following gene: 197118385

Centisome position: 49.98

GC content: 62.3

Gene sequence:

>984_bases
ATGGTCATACTTGCTGGAGACGTCGGCGGGACCTCCACCCGGCTAGCCTACTTCGAATCCGCTGCAACCGGGCTCGTGGT
GCTGGCCGAGGGGCGCTACCAAAGCCAGGAACACAGCAGCCTCTCCGACATCGTGCGGCGCTTTGCCGCCCAATCCCGCC
TGGATGCCGACAGGGCCTGCTTCGGCATAGCGGGACCGGTCATCGACGGGCGGGTAAGGACCCCGAACCTCCCCTGGAAC
ATCGACGGCAGCGAACTTGCCCAAGCCTTGGGCCTTGGCCAGGTGCGCCTGATCAACGATTTAGAGGCCAACACCTACGG
CATCGCGGAACTGAAGGCCCAGGACCTGCTGACGCTCAACCCCGGAGTGGCGGACCCCACAGGCACCATAGCCGTGGTTT
CCGCCGGCACCGGCCTTGGCGAGTCGCTTGCCTACTGGGACGGCTCCTCCCACAGGCCGCTTCCCAGCGAGGCGGGGCAT
GCCGATTTCGCAGCGCGCAACGAGATCGAGGCCGATCTTTTGCTATACCTCCAGGCGAAGCATGGCCGGGTCAGCTACGA
GCGCGTCCTGTCCGGTCCGGGGCTCCTCGATATCTACCGCTTTCTCAGGGACAGGCATTACTTCCAGGAGGATGAAGCCA
TCATTGCCGCCATGAACGCGGGCGACGCCCCTGCGGTCATCACCCGCGCCGCAATGGACGGAAGTTGCCCAATGTGCAGC
AAGGCTCTCGATATCTTCATCACCGTGTACGGTGCCGAAGCCGGGAACGCGGCTCTCAGATTTCTCGCCACCGGCGGAGT
CTATCTTGGCGGGGGGATTGCGCCCAAGATCCTGGACAAGCTGCGCGGGGCTTCCTTCATCGTTGCCTTTACCGCAAAAG
GGCGACTTAGCTCTTTGGTGCAAACAATTCCGGTGCACGTCATATTAAATGAGAGAACAGCACTGCTAGGTGCGGGAAGG
GCTGCTTCAATCTCATCCAGTTGA

Upstream 100 bases:

>100_bases
TCCCCGTGGCACCTGCCCCCACCCCCTAACCCCCTCCCGCGAGGGGAGGGGGGACCGAACGATGGTACAATTGGGCTTTG
AGCCCCATCAGGAGGGAGTC

Downstream 100 bases:

>100_bases
CCTTATCTTTTCACTGTGAACTGTCGTTGTCCTCTTTGTTAACGTGCAGCCGCCTCACAACCTTTCCACCCTGTTTACAT
TAAACGCTCTGTCTGCTTTT

Product: glucose 6-kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MVILAGDVGGTSTRLAYFESAATGLVVLAEGRYQSQEHSSLSDIVRRFAAQSRLDADRACFGIAGPVIDGRVRTPNLPWN
IDGSELAQALGLGQVRLINDLEANTYGIAELKAQDLLTLNPGVADPTGTIAVVSAGTGLGESLAYWDGSSHRPLPSEAGH
ADFAARNEIEADLLLYLQAKHGRVSYERVLSGPGLLDIYRFLRDRHYFQEDEAIIAAMNAGDAPAVITRAAMDGSCPMCS
KALDIFITVYGAEAGNAALRFLATGGVYLGGGIAPKILDKLRGASFIVAFTAKGRLSSLVQTIPVHVILNERTALLGAGR
AASISSS

Sequences:

>Translated_327_residues
MVILAGDVGGTSTRLAYFESAATGLVVLAEGRYQSQEHSSLSDIVRRFAAQSRLDADRACFGIAGPVIDGRVRTPNLPWN
IDGSELAQALGLGQVRLINDLEANTYGIAELKAQDLLTLNPGVADPTGTIAVVSAGTGLGESLAYWDGSSHRPLPSEAGH
ADFAARNEIEADLLLYLQAKHGRVSYERVLSGPGLLDIYRFLRDRHYFQEDEAIIAAMNAGDAPAVITRAAMDGSCPMCS
KALDIFITVYGAEAGNAALRFLATGGVYLGGGIAPKILDKLRGASFIVAFTAKGRLSSLVQTIPVHVILNERTALLGAGR
AASISSS
>Mature_327_residues
MVILAGDVGGTSTRLAYFESAATGLVVLAEGRYQSQEHSSLSDIVRRFAAQSRLDADRACFGIAGPVIDGRVRTPNLPWN
IDGSELAQALGLGQVRLINDLEANTYGIAELKAQDLLTLNPGVADPTGTIAVVSAGTGLGESLAYWDGSSHRPLPSEAGH
ADFAARNEIEADLLLYLQAKHGRVSYERVLSGPGLLDIYRFLRDRHYFQEDEAIIAAMNAGDAPAVITRAAMDGSCPMCS
KALDIFITVYGAEAGNAALRFLATGGVYLGGGIAPKILDKLRGASFIVAFTAKGRLSSLVQTIPVHVILNERTALLGAGR
AASISSS

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=321, Percent_Identity=36.4485981308411, Blast_Score=180, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34428; Mature: 34428

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILAGDVGGTSTRLAYFESAATGLVVLAEGRYQSQEHSSLSDIVRRFAAQSRLDADRAC
CEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
FGIAGPVIDGRVRTPNLPWNIDGSELAQALGLGQVRLINDLEANTYGIAELKAQDLLTLN
EEECCCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEC
PGVADPTGTIAVVSAGTGLGESLAYWDGSSHRPLPSEAGHADFAARNEIEADLLLYLQAK
CCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEEEC
HGRVSYERVLSGPGLLDIYRFLRDRHYFQEDEAIIAAMNAGDAPAVITRAAMDGSCPMCS
CCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHEEEHHCCCCCCHHH
KALDIFITVYGAEAGNAALRFLATGGVYLGGGIAPKILDKLRGASFIVAFTAKGRLSSLV
HHEEEEEEEEECCCCCCEEEEEEECCEEECCCCCHHHHHHHCCCEEEEEEECCCHHHHHH
QTIPVHVILNERTALLGAGRAASISSS
HHCCEEEEECCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MVILAGDVGGTSTRLAYFESAATGLVVLAEGRYQSQEHSSLSDIVRRFAAQSRLDADRAC
CEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
FGIAGPVIDGRVRTPNLPWNIDGSELAQALGLGQVRLINDLEANTYGIAELKAQDLLTLN
EEECCCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEC
PGVADPTGTIAVVSAGTGLGESLAYWDGSSHRPLPSEAGHADFAARNEIEADLLLYLQAK
CCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEEEC
HGRVSYERVLSGPGLLDIYRFLRDRHYFQEDEAIIAAMNAGDAPAVITRAAMDGSCPMCS
CCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHEEEHHCCCCCCHHH
KALDIFITVYGAEAGNAALRFLATGGVYLGGGIAPKILDKLRGASFIVAFTAKGRLSSLV
HHEEEEEEEEECCCCCCEEEEEEECCEEECCCCCHHHHHHHCCCEEEEEEECCCHHHHHH
QTIPVHVILNERTALLGAGRAASISSS
HHCCEEEEECCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA