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The map label for this gene is yoeB [H]

Identifier: 197118309

GI number: 197118309

Start: 2228334

End: 2228588

Strand: Reverse

Name: yoeB [H]

Synonym: Gbem_1926

Alternate gene names: 197118309

Gene position: 2228588-2228334 (Counterclockwise)

Preceding gene: 197118310

Following gene: 197118301

Centisome position: 48.29

GC content: 52.55

Gene sequence:

>255_bases
TTGAAGCTCATATTCTCGGAAAGCGCTTGGGAAGATTACCTGTTCTGGCAGAGCACAGACAAGAAGGTCGCCAAGCGCAT
CAACACCCTGATCAGGGAGATCCAGAGAAAGCCCCACGAAGGGATAGGGAAACCGGAACCACTGAGGCATGCTCTATCCG
GGTACTGGTCCCGCAGAATCAACGACGAGCATCGCATCGTGTACAAGGTCGAAGATGACTCAGTAATGATCGCGCAGCTT
CGTTACCACTACTAG

Upstream 100 bases:

>100_bases
AAACGGCGTACCTGCTGCGAAGCCCTAAAAACGTGCGGCGGCTGGTTGAATCTATAGCCGAGCTAGAGACCGGAAAGGCA
ACCGAACGGGAGCTGATCGA

Downstream 100 bases:

>100_bases
CAGGCAGATCGCTTCATACGGTGCCTGTCCCACCTCTTGGTTTTTCCTCTGTGTCTCCTCTGCGGTGAGCGTCTTTCCCC
TGTGGTTCCAGTTGTCAATT

Product: toxin Txe

Products: NA

Alternate protein names: Putative endoribonuclease YoeB; Putative mRNA interferase Yoeb [H]

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MKLIFSESAWEDYLFWQSTDKKVAKRINTLIREIQRKPHEGIGKPEPLRHALSGYWSRRINDEHRIVYKVEDDSVMIAQL
RYHY

Sequences:

>Translated_84_residues
MKLIFSESAWEDYLFWQSTDKKVAKRINTLIREIQRKPHEGIGKPEPLRHALSGYWSRRINDEHRIVYKVEDDSVMIAQL
RYHY
>Mature_84_residues
MKLIFSESAWEDYLFWQSTDKKVAKRINTLIREIQRKPHEGIGKPEPLRHALSGYWSRRINDEHRIVYKVEDDSVMIAQL
RYHY

Specific function: Part of a toxin-antitoxin (TA) module. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the pro

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=84, Percent_Identity=64.2857142857143, Blast_Score=125, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10189; Mature: 10189

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIFSESAWEDYLFWQSTDKKVAKRINTLIREIQRKPHEGIGKPEPLRHALSGYWSRRI
CCEEECCCCCCHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
NDEHRIVYKVEDDSVMIAQLRYHY
CCCCEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MKLIFSESAWEDYLFWQSTDKKVAKRINTLIREIQRKPHEGIGKPEPLRHALSGYWSRRI
CCEEECCCCCCHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
NDEHRIVYKVEDDSVMIAQLRYHY
CCCCEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]