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The map label for this gene is pgsA-1 [H]

Identifier: 197118255

GI number: 197118255

Start: 2166990

End: 2167583

Strand: Reverse

Name: pgsA-1 [H]

Synonym: Gbem_1872

Alternate gene names: 197118255

Gene position: 2167583-2166990 (Counterclockwise)

Preceding gene: 197118256

Following gene: 197118254

Centisome position: 46.97

GC content: 59.76

Gene sequence:

>594_bases
ATGTCCTCCCCCCCCCCAGCGAAGATAATGAACATCCCCAACATCCTCACCATGGTGCGGATCGCGGCGATACCGATTCT
GTGCGTCCTGCTCCTGTCGCCTGAGCGCGAGCCCTGCTTCTGGGCCGCGGCGCTCTTTGCCGCGGCGTCGGTGACCGACT
GGCTGGACGGCTACCTGGCCCGCCGCATGGGGATCGTCACCGTGTTCGGGAAGTTCCTGGACCCGATCGCCGACAAGCTG
ATCGTCATGGCCGCCCTGATCATGATCCTTCCCTTCGACCGGGTTCCGGCCTGGATGGTGCTGGTGATCCTCGGGCGGGA
GATGATCATCACCGGGCTGCGCGGCATCGCCTCCACCGAGGGGATCGTGATACCCGCGAGCAATCTGGGGAAGTTCAAGA
CCATCTTCCAACTGGTCGCCATCATCGGCCTGTTGCTGCACTACGACTACCGCTGGTTCTTTTCCATCGACCATCCATTG
CTGGTAGTGAACATGCACAACGTCGGGATGTTCTATCTTTGGATCGCCACTGTGATAACTATCTGGTCCGGTGTCGACTA
TCTCAATAAGTTCGTCAGGGTCATAGCCAAGTAG

Upstream 100 bases:

>100_bases
GCCAAGTACGGCGGCATCCCCCCCTTCAAGGAAACGCAGAGTTACGTGGCCAAAGTATTGAGTTACCGGAACAACTACAG
ATAGCGCAAAGGCATACAGC

Downstream 100 bases:

>100_bases
AAATTTCCCGTTGACACAGAGAATGTTTCAGGTTATAAACGGGTTCCTTCGATGCACAAGGCGGCATGGCCAAGTGGTAA
GGCAAAGGACTGCAAATCCT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSSPPPAKIMNIPNILTMVRIAAIPILCVLLLSPEREPCFWAAALFAAASVTDWLDGYLARRMGIVTVFGKFLDPIADKL
IVMAALIMILPFDRVPAWMVLVILGREMIITGLRGIASTEGIVIPASNLGKFKTIFQLVAIIGLLLHYDYRWFFSIDHPL
LVVNMHNVGMFYLWIATVITIWSGVDYLNKFVRVIAK

Sequences:

>Translated_197_residues
MSSPPPAKIMNIPNILTMVRIAAIPILCVLLLSPEREPCFWAAALFAAASVTDWLDGYLARRMGIVTVFGKFLDPIADKL
IVMAALIMILPFDRVPAWMVLVILGREMIITGLRGIASTEGIVIPASNLGKFKTIFQLVAIIGLLLHYDYRWFFSIDHPL
LVVNMHNVGMFYLWIATVITIWSGVDYLNKFVRVIAK
>Mature_196_residues
SSPPPAKIMNIPNILTMVRIAAIPILCVLLLSPEREPCFWAAALFAAASVTDWLDGYLARRMGIVTVFGKFLDPIADKLI
VMAALIMILPFDRVPAWMVLVILGREMIITGLRGIASTEGIVIPASNLGKFKTIFQLVAIIGLLLHYDYRWFFSIDHPLL
VVNMHNVGMFYLWIATVITIWSGVDYLNKFVRVIAK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=36.2162162162162, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320059, Length=211, Percent_Identity=30.3317535545024, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22031; Mature: 21900

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPPPAKIMNIPNILTMVRIAAIPILCVLLLSPEREPCFWAAALFAAASVTDWLDGYLA
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRMGIVTVFGKFLDPIADKLIVMAALIMILPFDRVPAWMVLVILGREMIITGLRGIASTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GIVIPASNLGKFKTIFQLVAIIGLLLHYDYRWFFSIDHPLLVVNMHNVGMFYLWIATVIT
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHHHHHHHHH
IWSGVDYLNKFVRVIAK
HHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSPPPAKIMNIPNILTMVRIAAIPILCVLLLSPEREPCFWAAALFAAASVTDWLDGYLA
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRMGIVTVFGKFLDPIADKLIVMAALIMILPFDRVPAWMVLVILGREMIITGLRGIASTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GIVIPASNLGKFKTIFQLVAIIGLLLHYDYRWFFSIDHPLLVVNMHNVGMFYLWIATVIT
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHHHHHHHHH
IWSGVDYLNKFVRVIAK
HHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]