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The map label for this gene is zraS [C]

Identifier: 197118087

GI number: 197118087

Start: 1965540

End: 1967255

Strand: Direct

Name: zraS [C]

Synonym: Gbem_1701

Alternate gene names: 197118087

Gene position: 1965540-1967255 (Clockwise)

Preceding gene: 197118086

Following gene: 197118088

Centisome position: 42.59

GC content: 61.71

Gene sequence:

>1716_bases
ATGAGCCAGAACAGCAACGAGGGCGACAATCTGTACCGCTACATCGTCGACATGATCCCCCAGATCGTCTGGACGGCCAC
GCCGGACGGAGGGCAGGATTTCGCCAACCTGCGCTGGTACGAGTTCAACGGCCTAACGCCGGGGGAGCCCGATCCCGAGC
CCTGGCGCAGCATCATCCATCCGGACGACGTGGCCATGACGGCCGAAAAGTGGCAGAATTCGCTGGCGACCGGGGAGCCT
TACTACTGCCTGCACCGAAACAAAAGGCACGACGGCGAGTACCGCTGGATGCTGTCGCGTGCGCTGGCGCAAAAGGACGA
GCATGGGCGGGTGGTCCGCTGGATCGGCAGCGGAACGGACATCACGGAGCAGAAGATAGCCGAGGCGGAGCTGATACGGT
ACCGCGACCACCTGGAAGAGCTGGTCCGGGAGCGGACGACGGAATTGGTCCTGGCCAAGGAGGTGGCGGAGGTTGCGGCC
AAGGCGGTTCGGGAAGCGAACGAACTGCTGGAAAAACGGGTAGAGGAGCGGACCGAGGAACTGAGGAGGACCGAAAAGGA
GCTGCGCCATGCGCAGAAGATGGAGGCTATCGGGACCCTCGCGGCGGGTATCGCGCACGATTTCAACAACATCCTTACCT
CCATCCTCGGATTCACCGACATGGTCCTGCACAAGATCCCCGAAGAAGGGACGGGGCGGCGGGAGATGGAGCAGGTGTTC
GTAGCGGCGCAGCGAGCCGCGGACCTGGTGCGCCAAATCCTCAGTTTCAGCAGGAGAAGCGATCAGGAAAGGAAGCCGGT
GCACCTCTCCGATATCGTCGAAGAGGCCTGCAAGCTGCTTCGTTCCTCGCTCCCTGCCACCGTGGAGATCGGCACGGAAT
GTTTTGCTTCCGAGGATGAAGACAAGGTCCTGGCCGACCCGATACAACTGCACCAGGTGCTGATGAACCTTTGCACCAAC
GCGGCACACGCCATGCAGCCTGAAGGCGGGATGCTGACCATCACGCTGACCGCGGTTGCGGCAGGATCGCCGGGGCTGCG
CTCTCTTCCTCTCTTTCTTTCGCGGGACTACATCAGGGTTGCCGTAAGGGACACTGGGCGCGGTATAGAGCCCTCGGTGC
TGGAGAGGATCTTCGACCCCTATTTCACCACCAAGCCGGTGGGGGAGGGGACGGGGCTAGGCCTCGCCGTGGTGCAGGGA
ATCGTGAAAAACCACGGGGGCGCCATCACGGTTCATAGCGAACCGGGAAAGGGAACCTGCTTCGAGGTTTTTCTCCCTAC
CGTGATTGGCGACGTGCTCCATGAGGCACAGATTCCAGAGCAGCTTCTGCACGGCTCGGAGCGGATCCTGTTCGTCGACG
ACGAGGAATCGCTCACCGTCCTTGGCAAGGGTATCCTGGACGCGCTCGGCTACAGCGTGGTCACCACCAACAGCAGCCGC
AGGGCACTGGAGATGTTCCGAGCCGACCCCGCCATTTTCGACCTGGTGATTACCGACCTGACCATGCCTGGGTTGGCCGG
AAAGGCCTTAGCCAAAGAGATCCATGCCCTGAGACCGGACCTCCCCATCATCCTTTGCACCGGGTACACGGAGAGCTTCG
ACGAGAAGGACCGGGAATACGGCATCCGCGCCTGCCTGATGAAGCCTTACACCTCGAAGATGCTGGGGCAGACCATACGG
ATGGTGCTGGGAGGGAAGACGACGTCAACCTGTTGA

Upstream 100 bases:

>100_bases
ACCAGACCTTGAACTGTGACAGAAGCTATGTATATTTAGCACAACAAAAACGCTGAATGTCAGCTGTATTTAGGCAAAGC
GCGCAGCGCATGAGGGATCG

Downstream 100 bases:

>100_bases
GGGGGTAGCTATGTGGAATTACGTGTCCCAGGCCCTGACGGCGCTGGTCTGTTTCGCCTTCATGGTGCTGTTCATGACGG
CCGCGGTGAAACGCGGCGTT

Product: PAS/PAC domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MSQNSNEGDNLYRYIVDMIPQIVWTATPDGGQDFANLRWYEFNGLTPGEPDPEPWRSIIHPDDVAMTAEKWQNSLATGEP
YYCLHRNKRHDGEYRWMLSRALAQKDEHGRVVRWIGSGTDITEQKIAEAELIRYRDHLEELVRERTTELVLAKEVAEVAA
KAVREANELLEKRVEERTEELRRTEKELRHAQKMEAIGTLAAGIAHDFNNILTSILGFTDMVLHKIPEEGTGRREMEQVF
VAAQRAADLVRQILSFSRRSDQERKPVHLSDIVEEACKLLRSSLPATVEIGTECFASEDEDKVLADPIQLHQVLMNLCTN
AAHAMQPEGGMLTITLTAVAAGSPGLRSLPLFLSRDYIRVAVRDTGRGIEPSVLERIFDPYFTTKPVGEGTGLGLAVVQG
IVKNHGGAITVHSEPGKGTCFEVFLPTVIGDVLHEAQIPEQLLHGSERILFVDDEESLTVLGKGILDALGYSVVTTNSSR
RALEMFRADPAIFDLVITDLTMPGLAGKALAKEIHALRPDLPIILCTGYTESFDEKDREYGIRACLMKPYTSKMLGQTIR
MVLGGKTTSTC

Sequences:

>Translated_571_residues
MSQNSNEGDNLYRYIVDMIPQIVWTATPDGGQDFANLRWYEFNGLTPGEPDPEPWRSIIHPDDVAMTAEKWQNSLATGEP
YYCLHRNKRHDGEYRWMLSRALAQKDEHGRVVRWIGSGTDITEQKIAEAELIRYRDHLEELVRERTTELVLAKEVAEVAA
KAVREANELLEKRVEERTEELRRTEKELRHAQKMEAIGTLAAGIAHDFNNILTSILGFTDMVLHKIPEEGTGRREMEQVF
VAAQRAADLVRQILSFSRRSDQERKPVHLSDIVEEACKLLRSSLPATVEIGTECFASEDEDKVLADPIQLHQVLMNLCTN
AAHAMQPEGGMLTITLTAVAAGSPGLRSLPLFLSRDYIRVAVRDTGRGIEPSVLERIFDPYFTTKPVGEGTGLGLAVVQG
IVKNHGGAITVHSEPGKGTCFEVFLPTVIGDVLHEAQIPEQLLHGSERILFVDDEESLTVLGKGILDALGYSVVTTNSSR
RALEMFRADPAIFDLVITDLTMPGLAGKALAKEIHALRPDLPIILCTGYTESFDEKDREYGIRACLMKPYTSKMLGQTIR
MVLGGKTTSTC
>Mature_570_residues
SQNSNEGDNLYRYIVDMIPQIVWTATPDGGQDFANLRWYEFNGLTPGEPDPEPWRSIIHPDDVAMTAEKWQNSLATGEPY
YCLHRNKRHDGEYRWMLSRALAQKDEHGRVVRWIGSGTDITEQKIAEAELIRYRDHLEELVRERTTELVLAKEVAEVAAK
AVREANELLEKRVEERTEELRRTEKELRHAQKMEAIGTLAAGIAHDFNNILTSILGFTDMVLHKIPEEGTGRREMEQVFV
AAQRAADLVRQILSFSRRSDQERKPVHLSDIVEEACKLLRSSLPATVEIGTECFASEDEDKVLADPIQLHQVLMNLCTNA
AHAMQPEGGMLTITLTAVAAGSPGLRSLPLFLSRDYIRVAVRDTGRGIEPSVLERIFDPYFTTKPVGEGTGLGLAVVQGI
VKNHGGAITVHSEPGKGTCFEVFLPTVIGDVLHEAQIPEQLLHGSERILFVDDEESLTVLGKGILDALGYSVVTTNSSRR
ALEMFRADPAIFDLVITDLTMPGLAGKALAKEIHALRPDLPIILCTGYTESFDEKDREYGIRACLMKPYTSKMLGQTIRM
VLGGKTTSTC

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=33.8775510204082, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI48994928, Length=411, Percent_Identity=26.5206812652068, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=30.4878048780488, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788713, Length=382, Percent_Identity=24.6073298429319, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081816, Length=415, Percent_Identity=25.0602409638554, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=30.3643724696356, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=28.3687943262411, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=430, Percent_Identity=24.1860465116279, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=26.5560165975104, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=28.099173553719, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=25.5905511811024, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=89, Percent_Identity=39.3258426966292, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63628; Mature: 63497

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNSNEGDNLYRYIVDMIPQIVWTATPDGGQDFANLRWYEFNGLTPGEPDPEPWRSIIH
CCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHCEEEEEECCCCCCCCCCHHHHHCCC
PDDVAMTAEKWQNSLATGEPYYCLHRNKRHDGEYRWMLSRALAQKDEHGRVVRWIGSGTD
CCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCC
ITEQKIAEAELIRYRDHLEELVRERTTELVLAKEVAEVAAKAVREANELLEKRVEERTEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRTEKELRHAQKMEAIGTLAAGIAHDFNNILTSILGFTDMVLHKIPEEGTGRREMEQVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VAAQRAADLVRQILSFSRRSDQERKPVHLSDIVEEACKLLRSSLPATVEIGTECFASEDE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCC
DKVLADPIQLHQVLMNLCTNAAHAMQPEGGMLTITLTAVAAGSPGLRSLPLFLSRDYIRV
CCHHHCHHHHHHHHHHHHHCHHHHCCCCCCEEEEEEEEEECCCCCCCCCHHHHCCCEEEE
AVRDTGRGIEPSVLERIFDPYFTTKPVGEGTGLGLAVVQGIVKNHGGAITVHSEPGKGTC
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
FEVFLPTVIGDVLHEAQIPEQLLHGSERILFVDDEESLTVLGKGILDALGYSVVTTNSSR
HHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCHH
RALEMFRADPAIFDLVITDLTMPGLAGKALAKEIHALRPDLPIILCTGYTESFDEKDREY
HHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
GIRACLMKPYTSKMLGQTIRMVLGGKTTSTC
HHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SQNSNEGDNLYRYIVDMIPQIVWTATPDGGQDFANLRWYEFNGLTPGEPDPEPWRSIIH
CCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHCEEEEEECCCCCCCCCCHHHHHCCC
PDDVAMTAEKWQNSLATGEPYYCLHRNKRHDGEYRWMLSRALAQKDEHGRVVRWIGSGTD
CCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCC
ITEQKIAEAELIRYRDHLEELVRERTTELVLAKEVAEVAAKAVREANELLEKRVEERTEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRTEKELRHAQKMEAIGTLAAGIAHDFNNILTSILGFTDMVLHKIPEEGTGRREMEQVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VAAQRAADLVRQILSFSRRSDQERKPVHLSDIVEEACKLLRSSLPATVEIGTECFASEDE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCC
DKVLADPIQLHQVLMNLCTNAAHAMQPEGGMLTITLTAVAAGSPGLRSLPLFLSRDYIRV
CCHHHCHHHHHHHHHHHHHCHHHHCCCCCCEEEEEEEEEECCCCCCCCCHHHHCCCEEEE
AVRDTGRGIEPSVLERIFDPYFTTKPVGEGTGLGLAVVQGIVKNHGGAITVHSEPGKGTC
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
FEVFLPTVIGDVLHEAQIPEQLLHGSERILFVDDEESLTVLGKGILDALGYSVVTTNSSR
HHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCHH
RALEMFRADPAIFDLVITDLTMPGLAGKALAKEIHALRPDLPIILCTGYTESFDEKDREY
HHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
GIRACLMKPYTSKMLGQTIRMVLGGKTTSTC
HHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA