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The map label for this gene is pepQ [H]

Identifier: 197118038

GI number: 197118038

Start: 1917634

End: 1918824

Strand: Direct

Name: pepQ [H]

Synonym: Gbem_1651

Alternate gene names: 197118038

Gene position: 1917634-1918824 (Clockwise)

Preceding gene: 197118037

Following gene: 197118039

Centisome position: 41.55

GC content: 62.22

Gene sequence:

>1191_bases
ATGCGGCTTACGCCAAAAAACGAGCTGGAATACCGGTACCGAAAACTGCAAAGCGAGATGGCCGGTGCAGGAATCGACGC
GGTCATCATGGTCCAGAACGCGGACCTCTTTTATTTCACCGGGACCGCGCAGGCAGGGAACCTTTACGTCCCCGCCTCCG
GGCGCCCCATCTACCTGGTACGCAGGGACTACCTCCGGGCCCGCATGGAAAGTGCCTTGGCCGAGGTGCTCCCTTCGTCC
TCCCTCAACGATCTCCCCGGTCTTGTTTCCGACCACGGCCATAGCGCGCCGAAAAGGCTAGGTCTCGAGCTCGACGTCCT
CCCGGTCAACCTCTACCTCAAATACCGCGCCCTTTACCCCGACGCCGAACTGGTCGACGCTTCCCCCCTGATACGCCGGG
TGCGCATGGTGAAGTCCCACTACGAAATTCACATCATGCAGGACGCCGGCAACCAGGCGGACAAGGTGTACAAAAAGGCT
GCCGAGACGATCCGCGAGGGGATCTGCGAGGTGGAACTTGCCGCCGAACTGGAGCGCTTCTCGCGCCTGGAAGGACACCA
GGGGCATGTGCGCATGCGTGCCTTCAACGGCGAGGTCGGCGGAGCCCAGGTGCTCGCAGGGCCGGATGCCGCGGCGCCCG
CAGCCGGCAACACCGCGCTGGGCGGTATGGGGCTTACCCCCGCCTTCGGCCACGGGGCCAGCTACAACAGGATCCGGCGC
GGCGAGCCGGTAGTGGTCGATTTCGCCAGTTGCTTCGACGGCTACCTGGTCGACCAGACCAGGGTCTTCGCCATAGGCTC
CGTCTCGGACCGGATGCGGCGCGGCTACCAAGACATGCTGCGCATAGAGGAACTGATGATGGAGATGGCCGAGGTGGGAA
CCAGTTGGGGGGGGATCTACCACGCCTGCCTCGATCTGGCCTGCGAGATGGGTTACGCGGACAACTTCATGGGGACCCCG
GGAAGCCAGGTTCCTTTCATCGGCCACGGGCTCGGCATCGAGATCGACGAATACCCTTTTATCGCCCGCGGTTTTGAAAG
TGAGACGCTCCAGGTGGGGATGGCGTTTGCCTTCGAACCGAAACTGGTGTTTCCCGGGGAAGGTGCGGTCGGCATCGAAA
ATTCGTTTTATCTCTCGGAACAGGGACTTAAGAGATTGACCTTTTCCCGGCAGGAGCTGGTACTGCTCTGA

Upstream 100 bases:

>100_bases
AGGGGACTGGCTTCGCAAGGCGCCGGTCCTAAGGGGACTGGCTCCGCAAGGTGCCTGTCCCCCTTGAGTCATTGAGTCAT
GGAAACGAGAAGGAGGAGCG

Downstream 100 bases:

>100_bases
CTTGAATTAAAATGTATGCAAAATAGTAAAACGGAATTTTTTGTATTGAAATTGGCCGAGGGCTTTGGTATACATTTGAA
AAATCTTTGTATACAGTATA

Product: prolidase family protein

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRLTPKNELEYRYRKLQSEMAGAGIDAVIMVQNADLFYFTGTAQAGNLYVPASGRPIYLVRRDYLRARMESALAEVLPSS
SLNDLPGLVSDHGHSAPKRLGLELDVLPVNLYLKYRALYPDAELVDASPLIRRVRMVKSHYEIHIMQDAGNQADKVYKKA
AETIREGICEVELAAELERFSRLEGHQGHVRMRAFNGEVGGAQVLAGPDAAAPAAGNTALGGMGLTPAFGHGASYNRIRR
GEPVVVDFASCFDGYLVDQTRVFAIGSVSDRMRRGYQDMLRIEELMMEMAEVGTSWGGIYHACLDLACEMGYADNFMGTP
GSQVPFIGHGLGIEIDEYPFIARGFESETLQVGMAFAFEPKLVFPGEGAVGIENSFYLSEQGLKRLTFSRQELVLL

Sequences:

>Translated_396_residues
MRLTPKNELEYRYRKLQSEMAGAGIDAVIMVQNADLFYFTGTAQAGNLYVPASGRPIYLVRRDYLRARMESALAEVLPSS
SLNDLPGLVSDHGHSAPKRLGLELDVLPVNLYLKYRALYPDAELVDASPLIRRVRMVKSHYEIHIMQDAGNQADKVYKKA
AETIREGICEVELAAELERFSRLEGHQGHVRMRAFNGEVGGAQVLAGPDAAAPAAGNTALGGMGLTPAFGHGASYNRIRR
GEPVVVDFASCFDGYLVDQTRVFAIGSVSDRMRRGYQDMLRIEELMMEMAEVGTSWGGIYHACLDLACEMGYADNFMGTP
GSQVPFIGHGLGIEIDEYPFIARGFESETLQVGMAFAFEPKLVFPGEGAVGIENSFYLSEQGLKRLTFSRQELVLL
>Mature_396_residues
MRLTPKNELEYRYRKLQSEMAGAGIDAVIMVQNADLFYFTGTAQAGNLYVPASGRPIYLVRRDYLRARMESALAEVLPSS
SLNDLPGLVSDHGHSAPKRLGLELDVLPVNLYLKYRALYPDAELVDASPLIRRVRMVKSHYEIHIMQDAGNQADKVYKKA
AETIREGICEVELAAELERFSRLEGHQGHVRMRAFNGEVGGAQVLAGPDAAAPAAGNTALGGMGLTPAFGHGASYNRIRR
GEPVVVDFASCFDGYLVDQTRVFAIGSVSDRMRRGYQDMLRIEELMMEMAEVGTSWGGIYHACLDLACEMGYADNFMGTP
GSQVPFIGHGLGIEIDEYPFIARGFESETLQVGMAFAFEPKLVFPGEGAVGIENSFYLSEQGLKRLTFSRQELVLL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=283, Percent_Identity=27.9151943462898, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 43592; Mature: 43592

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTPKNELEYRYRKLQSEMAGAGIDAVIMVQNADLFYFTGTAQAGNLYVPASGRPIYLV
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCCEEECCCCCEEEEE
RRDYLRARMESALAEVLPSSSLNDLPGLVSDHGHSAPKRLGLELDVLPVNLYLKYRALYP
EHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHCCCEEEEEEEEEEEEEEEECC
DAELVDASPLIRRVRMVKSHYEIHIMQDAGNQADKVYKKAAETIREGICEVELAAELERF
CCHHCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SRLEGHQGHVRMRAFNGEVGGAQVLAGPDAAAPAAGNTALGGMGLTPAFGHGASYNRIRR
HHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
GEPVVVDFASCFDGYLVDQTRVFAIGSVSDRMRRGYQDMLRIEELMMEMAEVGTSWGGIY
CCCEEEEHHHHCCCEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
HACLDLACEMGYADNFMGTPGSQVPFIGHGLGIEIDEYPFIARGFESETLQVGMAFAFEP
HHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEECCCCCEECCCCCCCEEEEEEEEECC
KLVFPGEGAVGIENSFYLSEQGLKRLTFSRQELVLL
EEEECCCCCCCCCCCEEECHHHHHHHHCCCCCEEEC
>Mature Secondary Structure
MRLTPKNELEYRYRKLQSEMAGAGIDAVIMVQNADLFYFTGTAQAGNLYVPASGRPIYLV
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCCEEECCCCCEEEEE
RRDYLRARMESALAEVLPSSSLNDLPGLVSDHGHSAPKRLGLELDVLPVNLYLKYRALYP
EHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHCCCEEEEEEEEEEEEEEEECC
DAELVDASPLIRRVRMVKSHYEIHIMQDAGNQADKVYKKAAETIREGICEVELAAELERF
CCHHCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SRLEGHQGHVRMRAFNGEVGGAQVLAGPDAAAPAAGNTALGGMGLTPAFGHGASYNRIRR
HHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
GEPVVVDFASCFDGYLVDQTRVFAIGSVSDRMRRGYQDMLRIEELMMEMAEVGTSWGGIY
CCCEEEEHHHHCCCEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
HACLDLACEMGYADNFMGTPGSQVPFIGHGLGIEIDEYPFIARGFESETLQVGMAFAFEP
HHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEECCCCCEECCCCCCCEEEEEEEEECC
KLVFPGEGAVGIENSFYLSEQGLKRLTFSRQELVLL
EEEECCCCCCCCCCCEEECHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]