Click here to switch to the map view.

The map label for this gene is ykcC [H]

Identifier: 197117993

GI number: 197117993

Start: 1864072

End: 1865046

Strand: Direct

Name: ykcC [H]

Synonym: Gbem_1606

Alternate gene names: 197117993

Gene position: 1864072-1865046 (Clockwise)

Preceding gene: 197117992

Following gene: 197117994

Centisome position: 40.39

GC content: 51.38

Gene sequence:

>975_bases
ATGAACTCACATTCCCAAAATGCTGACATTCTGTTCGCGACTGTGGTGGTGTCGGTATTCAACGAAGAAGAAGTGCTGCC
TGGTTTTTATGATGAACTGAGCCGGGTTCTCGGCCAATTGGGTGCTGCTGCAGAGGTTATTTTCGTAAACGATGGGAGCA
ATGACGGTAGTGCTGCGGTTCTTAAGGAACTGGCGAGCTTGGATCCTAGAGTAAAGATCATCAACCTTTCCCGCAATTAC
GGCCATGAAGCTGCGATGATCGCCGGCATAGACCACAGCAGGGGCAACCCGGTCATCTGCATGGACGCCGACCTCCAGCA
CCCGCCTGCTAAGATAGGCGAGATGCTTGAGCAGTACAGAAACGGCTTCGAGATCGTCTGCATGAAGAGGGTCGCCAGCA
ACAATCTCTCGCGCTTCGATAAGATGAAATCGTTGTTTTTCTATCGCCTGTTAAATCAACTTTCTCCCATGGAGTTCGAA
ACAGGCGCCTCCGATTTCTTCATGGTATCGAGAAGGGTGGCAAATATCCTAAAAGTTGAGTTTCGTGAAAGGATCCGTTT
CCTTAGGGGGTACGTTCAGACACTCGGATTCCGCAAGTCGGTCATAAGCTACACCGCGAGCGAGCGGGCGTGCGGCAAAA
GCAAGTACACGTTCTCCGATCTCTGCGGCCTTTCCCTCAACGCGTTCTTCAGCTTCAGCAACCTCCCGCTCAGGCTTGGG
ATAATCACCGGGTTAATAGTCGGTGGGTTCAGCATCCTGGTCGGCATTTACTCTATAGTGATGAGGTTCATCGGTAACGC
GCCGTCAGGGTACACCACCATCGTCGTCCTTGTCTCGTTCCTGTTCGCCATACAGTTCTTTATCACCGGTATCATCGGTG
AGTACATAGGGGTCATCCTGATACAGAGCAGGGAGAGGCCTATCTACCTAGTCGACTCAATGATGAACATCGCTGAGTGC
CATGAAGCTGAATAG

Upstream 100 bases:

>100_bases
AAAGGGCGCCTCCTCTCTTTGAGGTAACAGATTTGACGTCAATGACCTGATATGTCGCTGTGCAGGCTATGGATCGTCTT
GCTACGATAGGTGTTGCCTT

Downstream 100 bases:

>100_bases
GGATGTGACGGTAAGGATAAATTGGTTCCTGGACAATGTCGTTCCGCCGTTTCTGAGGGACAGCAGGATGTTCATGGGAG
TGTTGTTCTGGCTGCTGTTC

Product: family glycosyltransferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNSHSQNADILFATVVVSVFNEEEVLPGFYDELSRVLGQLGAAAEVIFVNDGSNDGSAAVLKELASLDPRVKIINLSRNY
GHEAAMIAGIDHSRGNPVICMDADLQHPPAKIGEMLEQYRNGFEIVCMKRVASNNLSRFDKMKSLFFYRLLNQLSPMEFE
TGASDFFMVSRRVANILKVEFRERIRFLRGYVQTLGFRKSVISYTASERACGKSKYTFSDLCGLSLNAFFSFSNLPLRLG
IITGLIVGGFSILVGIYSIVMRFIGNAPSGYTTIVVLVSFLFAIQFFITGIIGEYIGVILIQSRERPIYLVDSMMNIAEC
HEAE

Sequences:

>Translated_324_residues
MNSHSQNADILFATVVVSVFNEEEVLPGFYDELSRVLGQLGAAAEVIFVNDGSNDGSAAVLKELASLDPRVKIINLSRNY
GHEAAMIAGIDHSRGNPVICMDADLQHPPAKIGEMLEQYRNGFEIVCMKRVASNNLSRFDKMKSLFFYRLLNQLSPMEFE
TGASDFFMVSRRVANILKVEFRERIRFLRGYVQTLGFRKSVISYTASERACGKSKYTFSDLCGLSLNAFFSFSNLPLRLG
IITGLIVGGFSILVGIYSIVMRFIGNAPSGYTTIVVLVSFLFAIQFFITGIIGEYIGVILIQSRERPIYLVDSMMNIAEC
HEAE
>Mature_324_residues
MNSHSQNADILFATVVVSVFNEEEVLPGFYDELSRVLGQLGAAAEVIFVNDGSNDGSAAVLKELASLDPRVKIINLSRNY
GHEAAMIAGIDHSRGNPVICMDADLQHPPAKIGEMLEQYRNGFEIVCMKRVASNNLSRFDKMKSLFFYRLLNQLSPMEFE
TGASDFFMVSRRVANILKVEFRERIRFLRGYVQTLGFRKSVISYTASERACGKSKYTFSDLCGLSLNAFFSFSNLPLRLG
IITGLIVGGFSILVGIYSIVMRFIGNAPSGYTTIVVLVSFLFAIQFFITGIIGEYIGVILIQSRERPIYLVDSMMNIAEC
HEAE

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=156, Percent_Identity=31.4102564102564, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788692, Length=299, Percent_Identity=34.4481605351171, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1788588, Length=308, Percent_Identity=29.8701298701299, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 36061; Mature: 36061

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHSQNADILFATVVVSVFNEEEVLPGFYDELSRVLGQLGAAAEVIFVNDGSNDGSAAV
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
LKELASLDPRVKIINLSRNYGHEAAMIAGIDHSRGNPVICMDADLQHPPAKIGEMLEQYR
HHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
NGFEIVCMKRVASNNLSRFDKMKSLFFYRLLNQLSPMEFETGASDFFMVSRRVANILKVE
CCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
FRERIRFLRGYVQTLGFRKSVISYTASERACGKSKYTFSDLCGLSLNAFFSFSNLPLRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHEECCCCCCHHH
IITGLIVGGFSILVGIYSIVMRFIGNAPSGYTTIVVLVSFLFAIQFFITGIIGEYIGVIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IQSRERPIYLVDSMMNIAECHEAE
EECCCCCEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSHSQNADILFATVVVSVFNEEEVLPGFYDELSRVLGQLGAAAEVIFVNDGSNDGSAAV
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
LKELASLDPRVKIINLSRNYGHEAAMIAGIDHSRGNPVICMDADLQHPPAKIGEMLEQYR
HHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
NGFEIVCMKRVASNNLSRFDKMKSLFFYRLLNQLSPMEFETGASDFFMVSRRVANILKVE
CCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
FRERIRFLRGYVQTLGFRKSVISYTASERACGKSKYTFSDLCGLSLNAFFSFSNLPLRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHEECCCCCCHHH
IITGLIVGGFSILVGIYSIVMRFIGNAPSGYTTIVVLVSFLFAIQFFITGIIGEYIGVIL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IQSRERPIYLVDSMMNIAECHEAE
EECCCCCEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]