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The map label for this gene is lhr [H]

Identifier: 197117964

GI number: 197117964

Start: 1826862

End: 1831349

Strand: Reverse

Name: lhr [H]

Synonym: Gbem_1577

Alternate gene names: 197117964

Gene position: 1831349-1826862 (Counterclockwise)

Preceding gene: 197117967

Following gene: 308535250

Centisome position: 39.68

GC content: 64.75

Gene sequence:

>4488_bases
ATGCCGGAAAACGTCCTGAAATATTTCCACCCGCTGATAGCCGACTGGTTCAGGGAAACCCTGGGAGAACCGACACTGGT
ACAGTCGCGCGCCTGGAGCGAGGTGATGCAAGAGCGGCACGTGCTGGTGACTGCCCCGACCGGAAGCGGGAAGACGCTGG
CCGCTTTCTTGTGGGCTATCAACCAGTTGGTGACCGGCGCCTGGCCCTGCGGGGAAACGAGAGTGCTCTACGTCTCCCCG
CTTAAGGCGCTGAATAACGACGTGCGCCGCAACCTGACCGCGCCGCTTTTCGAATTGCGCCAGCACTTCGCGAAGCACCG
GGTTCCCTTCCCCGATATCGGGGTAATGACCCGCAGCGGCGACACACCAGGCGACGAGCGCCGAAGGATGCTGCGCCATC
CCCCGGAGATCCTGATCACCACACCCGAGAGTCTCAACATCCTCCTTACTTCAAAGGGAAGCAGGGCGACGCTCAACGGC
GTCGCCACCGTAATCCTGGACGAGATCCATGCGGTCGCCGGGGGGAAGCGGGGGACGCACCTGATCACGGCGGTGGAGCG
GCTGGTGCTCTTGAGCGGTGAATTCCAGCGCATCGCGCTGTCGGCCACGGTGCGGCCGCTGGAAACGGTGGCGGATTTCG
TGGGGGGGCTCCGACAAGTCGGAAGAGAGCATGTTCCCCGGCCCATCTCCATAGTCCGCGGGGACCGCGGGAAAAGCTTC
AGCCTCACTATCAGCGCTCCGGATGAGGCTGGGGAAAAACGAGCTGCGGACGAGTTATGGCCAGCGCTCACGGCCCGATT
CGCGGAGATCATCGAGCGGCACCGCTCCACCCTCTTCTTCGCCAACAGCAGGCGCACCACGGAAAAGGTCACCCGCCTGA
TCAACGAGCTCTCGGGCGAGGAGCTCGCCTATTCCCATCACGGCTCCCTGTCGCGGGAGATCCGCCTGGCCGTCGAGGAA
CGGCTGAAGCGCGGCGAGCTGAAGGCGATAGTGGCAACCAACTCGCTGGAATTAGGCATCGACATCGGTCGGCTGGACAG
CGTGGTGCTGATCCAGACGCCCCGCTCCATCTCCTCCGCCATTCAGCGCATCGGCCGCTCGGGGCACGGGGTGGGAGAGG
TGAGCTCCGGGATGCTCTTTCCCACCTACGGCATGGACTTCGTCTCGGCGGCAGTCATCGCCCGCGCCATCGCCGACGGC
GAGATCGAGGAGGTCCGCCCGGTGGAGAACCCACTCGACCTGCTGGCCCAGATCGTCCTCTCCATGGCACTGGCCGAGAC
CTGGCAGTTGGACGACCTTTACGACTTCCTGAAGGGGTGCTACCCGTACCGGAACCTTTCCCGGCAGCAGTTCGACCTGG
TGATCGGCATGCTGGAGGGAAGATACGCGGACTCGCACGTCCCCGAGCTGCGCCCGAGGGCGACGGTGGACCGGCTGGAG
CAGACCATCTCGACCCGCCCCGCGCTTTCCATGCTCATCTACCTGGAGGGAGGGACTATTCCCGAGAGGGGGTACTTCGA
GCTGCGCCTGAAGGAGAGCGGCGCCAAGATAGGGGAGCTGGACGAGGAGTTCGTCTGGGAGCGGAGGATCGGGGACACCT
TCGCGCTCGGGGCGCAGGTCTGGCAGATAACGGAGGTGACCCACAGCACGGTCCTGGTGGTGCCGGCCAGGAAGTCGCAG
CAGATCATTCCCTTCTGGAGGGCGGAGGAGCTGGACCGCGATTTCTTCTATTCCGAAAAGATCGCCTCGTTCCTGCAGCA
CTGCGACGAGCGGCTGGGGGAGCCGGAATTGATCGAGGAGCTGATGCAGCGGCATTTCATGGACCGGGACGCGGCTCGGG
CGCTGGAGAGCTACCTGAAACTGCAAAAGGAATCGACCAATGCCCCCCTTCCCCACCGCCACCATCTGCTGATCGAGCAG
TTCCGCGACCCGGCCGCAGGGGCGGAAACGGAGCAGATCATCCTGCACACCCTCTGGGGGAACGCGGTCAACCGCCCGTT
CACCTTCGCGCTCACAGCAGCCTGGGAGAAGCGCTACGGCTACCCGCTGCAGGCCTTCTACAACAACGACGGGATCGCGC
TATTGCTCCCCCACGACCTGGAGCAGCCGGAGCATCTCCTCGAACTGGTCACGCCGGAGAACATCGAGCCGCTGCTCAGG
GAATCGATGGAGGGGACCGGCTACTTCGGCGCGCGCTTCAGGGAGAACGCAGGGCGCGCGCTGCTGCTGTCCCGAAGCAA
CTTCAAAAGGAGGATGCCGCTTTGGCTGAATCGCCTCCGCTCCAAGAAGCTCCTCGCCTCCGTGCTCAGGTACCGCGACT
TCCCTGTGCTCTTGGAAACCTGGCGCTCCTGCCTTAAGGATGAATTCGACCTGGTGAACCTGAAGCGGCTTTTGGAGGAG
ATCCAGGATGGGAGCATCTATCTTACCCGGGTCCGCACCACGAAAGCATCCCCCTTCGCCCAGGGGCTCATCTGGCAGCA
GACCAACAAGTACGTCTACGAGGACGACACCCTGGGGGGCGGGCGGCGATCGGCGTTGGGAAGCGACCTCCCCAAGGAAA
TGGCGCTCTCCGCGCACCTGCGCCCGCGGCTCCCCGCCGAGTTGGTGCGGCTCTTCGAGCAGAAGCGGCAGCGTCTGGCC
GCGGGATACGCCCCCGATTCCCCCAGGGAGCTGATCGACTGGGCGAAGGAAAGGCTCCTGATCCCGTTTTCGGAATGGCC
GCTGCTCCTTGAAGCGGTCAGGCGCGACAGCGGCTTAGCGGAAGAGGAGCTGCTGCCGCAGATAGCCGGGCGGCTGGTCG
CTTTGACGCTGCCGAAAACTGAGGCCCCGCTGGTGGCAGCCGTCGAGATGATCCCGGAGCTGGCCCGGGCTTTTGCGCTG
GAGAAAGAGGAGCTGCCCTGGTCGCCGCTCGCCGGCGACGAGCGTATGACGGCACTTTTGCAGGAGTCGCTGGACCGGCT
CTGGGAGCGTAACAGTCTTGCCACAGACGAGGGAGCTGAGGAAGAAGAACCGGCCGCGGCAAGGTCGGTGGCAAGGTGGC
TGAGCTATTACGGTCCTATAGAGGTAACCAGGCTGCAACTGACTTTGGGGCTCTCCGACCAGCTGCTGCGCGATACCTTG
CAGACGCTGGAAGAGACCGGCGCCATGCTGATCGACCAGTTCACCGAGGCGGCAACGGAGCCGCAGATCTGCGATGCAGT
CAACCTTGAGGCGCTGCTGCGCATGCTGCGCAGATCGAGAAAGCCCGCCTTCGAGGCGCTGGATCTCTCCCGGCTCCCCC
TGTTCCTGGCGACGGTGCAGGGGCTTGCCGCTCCGGGGAGTTCCGCGGACGACCTAAGGGACAGGCTGGAGCAGCTGCTG
GGCGCGCCGCTTTCGGCACCCCTCTGGGAAGAAGAGGTTTTGCCCGCCCGCCTTGCCCCCTACTTCGGGGCCTGGCTGGA
TAGCCTCATGCAGTCCAGCGACCTCCTTTGGTTTGGCTGCGGCCCGAAGAGACTCTCCTTCGCCTTTCCGGAGGACTTGG
ACCTGTTTCAGATTCAGGAAAGGGAGAATGCACCTCTGGAGCCGGGGGCCAAGCCCCCCTCCCCTCTTATCCCCGATCCC
CGGGGGCACTACAGCCTCACCGCGATCTGTCTCATGTCGGGCCTCTCCCCGGCGACGGTGACGAAGCAACTCTGGCAAGA
GGCCTGGAGCGGGGAGCTCGGCAACGACTCTTTCGCTGCGGTGCGCATGGGGATTCTGAACCGGTTCGAGCTGCCGCAAC
ACGCCGCGAGCCACAGCCGGCACCTAAGGCGCCCGTCCGGAAACCGCTGGAGCCGCGTGCAGGAAGGCCCGGGCAATTGG
TATCTACTCCCGGCGCAGGAAGGGGCGACCGACGCGCTGGAAATAGAGGAGAGGAACAAGGACCGGGTGCGCGTGCTGCT
GGAGCGCTACGGCATCCTCTTCAGGGAGCTTCTGGCGCGCGAGCTCCCTCCCCTGCAGTGGAGCCGGCTGTTCAGGACGC
TGCGCATCATGGAGATGTCCGGGGAGGTGCTTTCGGGGAGCTTCTTCACGGGCATACCGGGGCTGCAGTTCATCTCCCCG
GAGGCGTACCGGCAGCTTGAGCGCGGGATGCCGACGGACGCCGTCTACTGGCTCAACGCCGCCGACCCCGCCTCCCTTTG
CGGCATCGGGCTTGACGGGTTGCCGTATCGCCTCCCCGCCCGCCTCCCCTCGACCCACCTCGTGTACCGGGGCGCAGAGC
TGGTGCTGGTATCGAGGCGTTACGGCAAGGAGCTTGAGATTAAGGTGGAGCCGGACGACGAGAGGCTCCCGGAGTACCTG
CGCTTTTTCCACACCCTCCTTTCCCGCGACTTCAACCCGCTGAAGAGAATCCAGGTCGAGCGGATCAACGGGGAGCCCGC
CGCGTCCTCTCCTTACGCCGGCGCCCTGCTCTCCTTCGGGTTCCAGCAGGCCTACAGCGGCCTGGAGCTGTGGCGAAAAT
ACAGCTGA

Upstream 100 bases:

>100_bases
CTCTAGTTCCTATCGGCTGGAGTCAACGCGGCTCAAGCAGAATCGAAAGATGACTGCGAGAAAACTTGATTAACTTCCCT
CTTGACCTAAAGTCATAGCT

Downstream 100 bases:

>100_bases
TCCTCCAAGCAGTCCCCACCTCCCATAACGAAGTAACAAGGTTCTACCACATCCGCACACATGCCCTCGCCCCTAAACAT
ATCCTCTACACCGCGCCAGA

Product: ATP-dependent helicase Lhr

Products: NA

Alternate protein names: Large helicase-related protein [H]

Number of amino acids: Translated: 1495; Mature: 1494

Protein sequence:

>1495_residues
MPENVLKYFHPLIADWFRETLGEPTLVQSRAWSEVMQERHVLVTAPTGSGKTLAAFLWAINQLVTGAWPCGETRVLYVSP
LKALNNDVRRNLTAPLFELRQHFAKHRVPFPDIGVMTRSGDTPGDERRRMLRHPPEILITTPESLNILLTSKGSRATLNG
VATVILDEIHAVAGGKRGTHLITAVERLVLLSGEFQRIALSATVRPLETVADFVGGLRQVGREHVPRPISIVRGDRGKSF
SLTISAPDEAGEKRAADELWPALTARFAEIIERHRSTLFFANSRRTTEKVTRLINELSGEELAYSHHGSLSREIRLAVEE
RLKRGELKAIVATNSLELGIDIGRLDSVVLIQTPRSISSAIQRIGRSGHGVGEVSSGMLFPTYGMDFVSAAVIARAIADG
EIEEVRPVENPLDLLAQIVLSMALAETWQLDDLYDFLKGCYPYRNLSRQQFDLVIGMLEGRYADSHVPELRPRATVDRLE
QTISTRPALSMLIYLEGGTIPERGYFELRLKESGAKIGELDEEFVWERRIGDTFALGAQVWQITEVTHSTVLVVPARKSQ
QIIPFWRAEELDRDFFYSEKIASFLQHCDERLGEPELIEELMQRHFMDRDAARALESYLKLQKESTNAPLPHRHHLLIEQ
FRDPAAGAETEQIILHTLWGNAVNRPFTFALTAAWEKRYGYPLQAFYNNDGIALLLPHDLEQPEHLLELVTPENIEPLLR
ESMEGTGYFGARFRENAGRALLLSRSNFKRRMPLWLNRLRSKKLLASVLRYRDFPVLLETWRSCLKDEFDLVNLKRLLEE
IQDGSIYLTRVRTTKASPFAQGLIWQQTNKYVYEDDTLGGGRRSALGSDLPKEMALSAHLRPRLPAELVRLFEQKRQRLA
AGYAPDSPRELIDWAKERLLIPFSEWPLLLEAVRRDSGLAEEELLPQIAGRLVALTLPKTEAPLVAAVEMIPELARAFAL
EKEELPWSPLAGDERMTALLQESLDRLWERNSLATDEGAEEEEPAAARSVARWLSYYGPIEVTRLQLTLGLSDQLLRDTL
QTLEETGAMLIDQFTEAATEPQICDAVNLEALLRMLRRSRKPAFEALDLSRLPLFLATVQGLAAPGSSADDLRDRLEQLL
GAPLSAPLWEEEVLPARLAPYFGAWLDSLMQSSDLLWFGCGPKRLSFAFPEDLDLFQIQERENAPLEPGAKPPSPLIPDP
RGHYSLTAICLMSGLSPATVTKQLWQEAWSGELGNDSFAAVRMGILNRFELPQHAASHSRHLRRPSGNRWSRVQEGPGNW
YLLPAQEGATDALEIEERNKDRVRVLLERYGILFRELLARELPPLQWSRLFRTLRIMEMSGEVLSGSFFTGIPGLQFISP
EAYRQLERGMPTDAVYWLNAADPASLCGIGLDGLPYRLPARLPSTHLVYRGAELVLVSRRYGKELEIKVEPDDERLPEYL
RFFHTLLSRDFNPLKRIQVERINGEPAASSPYAGALLSFGFQQAYSGLELWRKYS

Sequences:

>Translated_1495_residues
MPENVLKYFHPLIADWFRETLGEPTLVQSRAWSEVMQERHVLVTAPTGSGKTLAAFLWAINQLVTGAWPCGETRVLYVSP
LKALNNDVRRNLTAPLFELRQHFAKHRVPFPDIGVMTRSGDTPGDERRRMLRHPPEILITTPESLNILLTSKGSRATLNG
VATVILDEIHAVAGGKRGTHLITAVERLVLLSGEFQRIALSATVRPLETVADFVGGLRQVGREHVPRPISIVRGDRGKSF
SLTISAPDEAGEKRAADELWPALTARFAEIIERHRSTLFFANSRRTTEKVTRLINELSGEELAYSHHGSLSREIRLAVEE
RLKRGELKAIVATNSLELGIDIGRLDSVVLIQTPRSISSAIQRIGRSGHGVGEVSSGMLFPTYGMDFVSAAVIARAIADG
EIEEVRPVENPLDLLAQIVLSMALAETWQLDDLYDFLKGCYPYRNLSRQQFDLVIGMLEGRYADSHVPELRPRATVDRLE
QTISTRPALSMLIYLEGGTIPERGYFELRLKESGAKIGELDEEFVWERRIGDTFALGAQVWQITEVTHSTVLVVPARKSQ
QIIPFWRAEELDRDFFYSEKIASFLQHCDERLGEPELIEELMQRHFMDRDAARALESYLKLQKESTNAPLPHRHHLLIEQ
FRDPAAGAETEQIILHTLWGNAVNRPFTFALTAAWEKRYGYPLQAFYNNDGIALLLPHDLEQPEHLLELVTPENIEPLLR
ESMEGTGYFGARFRENAGRALLLSRSNFKRRMPLWLNRLRSKKLLASVLRYRDFPVLLETWRSCLKDEFDLVNLKRLLEE
IQDGSIYLTRVRTTKASPFAQGLIWQQTNKYVYEDDTLGGGRRSALGSDLPKEMALSAHLRPRLPAELVRLFEQKRQRLA
AGYAPDSPRELIDWAKERLLIPFSEWPLLLEAVRRDSGLAEEELLPQIAGRLVALTLPKTEAPLVAAVEMIPELARAFAL
EKEELPWSPLAGDERMTALLQESLDRLWERNSLATDEGAEEEEPAAARSVARWLSYYGPIEVTRLQLTLGLSDQLLRDTL
QTLEETGAMLIDQFTEAATEPQICDAVNLEALLRMLRRSRKPAFEALDLSRLPLFLATVQGLAAPGSSADDLRDRLEQLL
GAPLSAPLWEEEVLPARLAPYFGAWLDSLMQSSDLLWFGCGPKRLSFAFPEDLDLFQIQERENAPLEPGAKPPSPLIPDP
RGHYSLTAICLMSGLSPATVTKQLWQEAWSGELGNDSFAAVRMGILNRFELPQHAASHSRHLRRPSGNRWSRVQEGPGNW
YLLPAQEGATDALEIEERNKDRVRVLLERYGILFRELLARELPPLQWSRLFRTLRIMEMSGEVLSGSFFTGIPGLQFISP
EAYRQLERGMPTDAVYWLNAADPASLCGIGLDGLPYRLPARLPSTHLVYRGAELVLVSRRYGKELEIKVEPDDERLPEYL
RFFHTLLSRDFNPLKRIQVERINGEPAASSPYAGALLSFGFQQAYSGLELWRKYS
>Mature_1494_residues
PENVLKYFHPLIADWFRETLGEPTLVQSRAWSEVMQERHVLVTAPTGSGKTLAAFLWAINQLVTGAWPCGETRVLYVSPL
KALNNDVRRNLTAPLFELRQHFAKHRVPFPDIGVMTRSGDTPGDERRRMLRHPPEILITTPESLNILLTSKGSRATLNGV
ATVILDEIHAVAGGKRGTHLITAVERLVLLSGEFQRIALSATVRPLETVADFVGGLRQVGREHVPRPISIVRGDRGKSFS
LTISAPDEAGEKRAADELWPALTARFAEIIERHRSTLFFANSRRTTEKVTRLINELSGEELAYSHHGSLSREIRLAVEER
LKRGELKAIVATNSLELGIDIGRLDSVVLIQTPRSISSAIQRIGRSGHGVGEVSSGMLFPTYGMDFVSAAVIARAIADGE
IEEVRPVENPLDLLAQIVLSMALAETWQLDDLYDFLKGCYPYRNLSRQQFDLVIGMLEGRYADSHVPELRPRATVDRLEQ
TISTRPALSMLIYLEGGTIPERGYFELRLKESGAKIGELDEEFVWERRIGDTFALGAQVWQITEVTHSTVLVVPARKSQQ
IIPFWRAEELDRDFFYSEKIASFLQHCDERLGEPELIEELMQRHFMDRDAARALESYLKLQKESTNAPLPHRHHLLIEQF
RDPAAGAETEQIILHTLWGNAVNRPFTFALTAAWEKRYGYPLQAFYNNDGIALLLPHDLEQPEHLLELVTPENIEPLLRE
SMEGTGYFGARFRENAGRALLLSRSNFKRRMPLWLNRLRSKKLLASVLRYRDFPVLLETWRSCLKDEFDLVNLKRLLEEI
QDGSIYLTRVRTTKASPFAQGLIWQQTNKYVYEDDTLGGGRRSALGSDLPKEMALSAHLRPRLPAELVRLFEQKRQRLAA
GYAPDSPRELIDWAKERLLIPFSEWPLLLEAVRRDSGLAEEELLPQIAGRLVALTLPKTEAPLVAAVEMIPELARAFALE
KEELPWSPLAGDERMTALLQESLDRLWERNSLATDEGAEEEEPAAARSVARWLSYYGPIEVTRLQLTLGLSDQLLRDTLQ
TLEETGAMLIDQFTEAATEPQICDAVNLEALLRMLRRSRKPAFEALDLSRLPLFLATVQGLAAPGSSADDLRDRLEQLLG
APLSAPLWEEEVLPARLAPYFGAWLDSLMQSSDLLWFGCGPKRLSFAFPEDLDLFQIQERENAPLEPGAKPPSPLIPDPR
GHYSLTAICLMSGLSPATVTKQLWQEAWSGELGNDSFAAVRMGILNRFELPQHAASHSRHLRRPSGNRWSRVQEGPGNWY
LLPAQEGATDALEIEERNKDRVRVLLERYGILFRELLARELPPLQWSRLFRTLRIMEMSGEVLSGSFFTGIPGLQFISPE
AYRQLERGMPTDAVYWLNAADPASLCGIGLDGLPYRLPARLPSTHLVYRGAELVLVSRRYGKELEIKVEPDDERLPEYLR
FFHTLLSRDFNPLKRIQVERINGEPAASSPYAGALLSFGFQQAYSGLELWRKYS

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=1586, Percent_Identity=31.7780580075662, Blast_Score=607, Evalue=1e-174,
Organism=Caenorhabditis elegans, GI17537127, Length=326, Percent_Identity=25.7668711656442, Blast_Score=74, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=361, Percent_Identity=27.4238227146814, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321710, Length=357, Percent_Identity=25.7703081232493, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI9755332, Length=465, Percent_Identity=23.010752688172, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 168857; Mature: 168726

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENVLKYFHPLIADWFRETLGEPTLVQSRAWSEVMQERHVLVTAPTGSGKTLAAFLWAI
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
NQLVTGAWPCGETRVLYVSPLKALNNDVRRNLTAPLFELRQHFAKHRVPFPDIGVMTRSG
HHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEECCC
DTPGDERRRMLRHPPEILITTPESLNILLTSKGSRATLNGVATVILDEIHAVAGGKRGTH
CCCCHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
LITAVERLVLLSGEFQRIALSATVRPLETVADFVGGLRQVGREHVPRPISIVRGDRGKSF
HHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEE
SLTISAPDEAGEKRAADELWPALTARFAEIIERHRSTLFFANSRRTTEKVTRLINELSGE
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCC
ELAYSHHGSLSREIRLAVEERLKRGELKAIVATNSLELGIDIGRLDSVVLIQTPRSISSA
CEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCEEECEECCCCCCEEEEECCHHHHHH
IQRIGRSGHGVGEVSSGMLFPTYGMDFVSAAVIARAIADGEIEEVRPVENPLDLLAQIVL
HHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHH
SMALAETWQLDDLYDFLKGCYPYRNLSRQQFDLVIGMLEGRYADSHVPELRPRATVDRLE
HHHHHHHCCHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QTISTRPALSMLIYLEGGTIPERGYFELRLKESGAKIGELDEEFVWERRIGDTFALGAQV
HHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHH
WQITEVTHSTVLVVPARKSQQIIPFWRAEELDRDFFYSEKIASFLQHCDERLGEPELIEE
HHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LMQRHFMDRDAARALESYLKLQKESTNAPLPHRHHLLIEQFRDPAAGAETEQIILHTLWG
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NAVNRPFTFALTAAWEKRYGYPLQAFYNNDGIALLLPHDLEQPEHLLELVTPENIEPLLR
CCCCCCEEEEEEHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHHHHCCCCCCHHHHH
ESMEGTGYFGARFRENAGRALLLSRSNFKRRMPLWLNRLRSKKLLASVLRYRDFPVLLET
HCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WRSCLKDEFDLVNLKRLLEEIQDGSIYLTRVRTTKASPFAQGLIWQQTNKYVYEDDTLGG
HHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCHHCCCCCEEEECCCCCC
GRRSALGSDLPKEMALSAHLRPRLPAELVRLFEQKRQRLAAGYAPDSPRELIDWAKERLL
CCHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEE
IPFSEWPLLLEAVRRDSGLAEEELLPQIAGRLVALTLPKTEAPLVAAVEMIPELARAFAL
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHC
EKEELPWSPLAGDERMTALLQESLDRLWERNSLATDEGAEEEEPAAARSVARWLSYYGPI
CHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
EVTRLQLTLGLSDQLLRDTLQTLEETGAMLIDQFTEAATEPQICDAVNLEALLRMLRRSR
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCC
KPAFEALDLSRLPLFLATVQGLAAPGSSADDLRDRLEQLLGAPLSAPLWEEEVLPARLAP
CCHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHH
YFGAWLDSLMQSSDLLWFGCGPKRLSFAFPEDLDLFQIQERENAPLEPGAKPPSPLIPDP
HHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCC
RGHYSLTAICLMSGLSPATVTKQLWQEAWSGELGNDSFAAVRMGILNRFELPQHAASHSR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
HLRRPSGNRWSRVQEGPGNWYLLPAQEGATDALEIEERNKDRVRVLLERYGILFRELLAR
HHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ELPPLQWSRLFRTLRIMEMSGEVLSGSFFTGIPGLQFISPEAYRQLERGMPTDAVYWLNA
HCCCHHHHHHHHHHHHHHHCCCHHCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEECC
ADPASLCGIGLDGLPYRLPARLPSTHLVYRGAELVLVSRRYGKELEIKVEPDDERLPEYL
CCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCHHHHHHHH
RFFHTLLSRDFNPLKRIQVERINGEPAASSPYAGALLSFGFQQAYSGLELWRKYS
HHHHHHHHCCCCHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PENVLKYFHPLIADWFRETLGEPTLVQSRAWSEVMQERHVLVTAPTGSGKTLAAFLWAI
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
NQLVTGAWPCGETRVLYVSPLKALNNDVRRNLTAPLFELRQHFAKHRVPFPDIGVMTRSG
HHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEECCC
DTPGDERRRMLRHPPEILITTPESLNILLTSKGSRATLNGVATVILDEIHAVAGGKRGTH
CCCCHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
LITAVERLVLLSGEFQRIALSATVRPLETVADFVGGLRQVGREHVPRPISIVRGDRGKSF
HHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEE
SLTISAPDEAGEKRAADELWPALTARFAEIIERHRSTLFFANSRRTTEKVTRLINELSGE
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCC
ELAYSHHGSLSREIRLAVEERLKRGELKAIVATNSLELGIDIGRLDSVVLIQTPRSISSA
CEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCEEECEECCCCCCEEEEECCHHHHHH
IQRIGRSGHGVGEVSSGMLFPTYGMDFVSAAVIARAIADGEIEEVRPVENPLDLLAQIVL
HHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHH
SMALAETWQLDDLYDFLKGCYPYRNLSRQQFDLVIGMLEGRYADSHVPELRPRATVDRLE
HHHHHHHCCHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QTISTRPALSMLIYLEGGTIPERGYFELRLKESGAKIGELDEEFVWERRIGDTFALGAQV
HHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHH
WQITEVTHSTVLVVPARKSQQIIPFWRAEELDRDFFYSEKIASFLQHCDERLGEPELIEE
HHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LMQRHFMDRDAARALESYLKLQKESTNAPLPHRHHLLIEQFRDPAAGAETEQIILHTLWG
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NAVNRPFTFALTAAWEKRYGYPLQAFYNNDGIALLLPHDLEQPEHLLELVTPENIEPLLR
CCCCCCEEEEEEHHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHHHHCCCCCCHHHHH
ESMEGTGYFGARFRENAGRALLLSRSNFKRRMPLWLNRLRSKKLLASVLRYRDFPVLLET
HCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
WRSCLKDEFDLVNLKRLLEEIQDGSIYLTRVRTTKASPFAQGLIWQQTNKYVYEDDTLGG
HHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCHHCCCCCEEEECCCCCC
GRRSALGSDLPKEMALSAHLRPRLPAELVRLFEQKRQRLAAGYAPDSPRELIDWAKERLL
CCHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEE
IPFSEWPLLLEAVRRDSGLAEEELLPQIAGRLVALTLPKTEAPLVAAVEMIPELARAFAL
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHC
EKEELPWSPLAGDERMTALLQESLDRLWERNSLATDEGAEEEEPAAARSVARWLSYYGPI
CHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
EVTRLQLTLGLSDQLLRDTLQTLEETGAMLIDQFTEAATEPQICDAVNLEALLRMLRRSR
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCC
KPAFEALDLSRLPLFLATVQGLAAPGSSADDLRDRLEQLLGAPLSAPLWEEEVLPARLAP
CCHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHH
YFGAWLDSLMQSSDLLWFGCGPKRLSFAFPEDLDLFQIQERENAPLEPGAKPPSPLIPDP
HHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCC
RGHYSLTAICLMSGLSPATVTKQLWQEAWSGELGNDSFAAVRMGILNRFELPQHAASHSR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
HLRRPSGNRWSRVQEGPGNWYLLPAQEGATDALEIEERNKDRVRVLLERYGILFRELLAR
HHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ELPPLQWSRLFRTLRIMEMSGEVLSGSFFTGIPGLQFISPEAYRQLERGMPTDAVYWLNA
HCCCHHHHHHHHHHHHHHHCCCHHCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEECC
ADPASLCGIGLDGLPYRLPARLPSTHLVYRGAELVLVSRRYGKELEIKVEPDDERLPEYL
CCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCHHHHHHHH
RFFHTLLSRDFNPLKRIQVERINGEPAASSPYAGALLSFGFQQAYSGLELWRKYS
HHHHHHHHCCCCHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7559321; 9097039; 9278503; 1460056 [H]