Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 197117893

GI number: 197117893

Start: 1743585

End: 1745699

Strand: Direct

Name: yciR [C]

Synonym: Gbem_1506

Alternate gene names: 197117893

Gene position: 1743585-1745699 (Clockwise)

Preceding gene: 197117892

Following gene: 197117894

Centisome position: 37.78

GC content: 62.88

Gene sequence:

>2115_bases
ATGCTGACTAGGAAAGCAAAGCGCAGCACACCGCTCGTCATGGTCGTGGACGACGACCAGGCAGTGCGCCTTCTGGCCCG
GGAGACCCTGGAGAACTCCGGCTTCGCCGTGCGCGACGTGGAAAACGGCGAGCAGGCGCTGGAGGAGTTCGATGTGCACG
CGCCAGACATCGTGCTCCTGGACGTGATGATGCCGGGCATCGACGGCTTCTCCGTCTGCAGCGCCATCCGGCGCACCGCC
TCCGGGCGGGACACGCCGGTTTTGATGATGACCGGCCTGGACGACCTGGAGTCAATAGACTGCGCCTACGAGGCGGGGGC
CACCGATTTCATCACCAAACCGATCAACTGGCACGTGCTCGGGTACCGGGTGAGCTACATGCTGAGGGCGAGCGGCGCCC
TGGAGCAGTTGAGGGAGAGCAGGGCGGGCTTAGCTCACGCCCAGAGCCTCGCCCATATCGGGAGTTGGGAGTGGGACCTC
GTTACCGGCGAGATCCGGTGCTCCGAGGAGGTCTACAGCATCTGCAGCATCGAGCGCTCTTTCAAAGGGGGAAACCCCAT
CCTCGACCCGGTGCACCCCCTGGACCGCGGTTTCGTGCAGGGATCCATCGACGAGGCGATCGGCAAGCGCGCACCGCTTT
CCTTCGACTATCGGATCACGCTGGGGGGGGGAGAGCGCACCCTGCACGCCGAGCTGGTGACGGTACTGGACGAGCAGGGC
GAGGCTGTCTGCTTAACTGGAACTATCCAGGACATCACCGAGAGAAAGCGCGCCGAGGAACAGATCCGGCTCCTGGCTTA
CTACGACGCGCTGACCGGCCTTCCCAACCGCCGCTTCTTCCTGCAGCAGTTGGAGCAGGCCCTGGTCTTCGCCAACCGCT
ACGACCGGATGCTCGCGGTCCTCTTCCTCGACCTGGACCGCTTCAAGCTCGTCAACGACACCCTCGGGCACGGGGTAGGG
GACCGCCTGCTGCAGGACGTGGCCGACCGGCTGCTGCGCTGCGTCCGCAGAGGGGACTGTCTCGCCCGCGCCGACGAGGA
GTGCCCGCCGTCCCTGGTCTCGCGCCTGGGAGGGGACGAGTTCACCATCATGCTCTCCGACATAGAGCACTTCCAGGACG
TGGCCAAGATCGCCCGCCGAATCCTTGAGGCAGTTTCAGTTCCCTACTCGCTAGAAGGGCAGGAGGTTTTCGTCTCCACC
AGCATCGGCATCAGCCTCTACCCCTTCGACGCCACTACGGCGAGCGACCTGATCCGGAACGCGGACGGCGCCATGTACCA
GGCCAAGGAACAGGGGAGAAACGGCTACCAGATCTACGACGAGTCCATGAACGCCAAGGCGCTGGAGCGGATCATACTGG
AAAGCCAGCTGCACAAGGCGCTCAAGGAGGAGGAATTCATCGTCTACTACCAGCCGCAGGTCTCAAACCAAAGCGGACGT
GTGGTGGGGATTGAGGCGCTGGTGCGCTGGAACTCCAAGGAACTGGGCCTCGTCGAACCGGGGCGTTTCCTACCGCTGGC
CGAGGAGATCGGGCTGGTGATCCAGATCGACCAGTGGGTGATGCGGGAAGCATGCCGGCAACACAAGCTCTGGCTGGACG
CGGGGTTCCCGCCGGTGACGCTTGCCATCAACATCTCAGGCCAGCAATTCATGAAAAACGAGCTTTTGGAGACGGTGACC
TCGGTCCTGAAAGAGAGCGGGCTCGACCCGGGGCTTTTGGAACTGGAACTTACCGAGGGAGTGCTCATGGCGCACACCGA
ACGCACTGTAAAGACGCTGCAGGCCCTGAAAGGGATGGGGGTGAGGCTCGCCATCGACGACTTCGGGACCGGCTTCTCCT
CGCTCTCCTATTTAAAGCGCTTCCCGCTTGACGTCCTCAAGATCGACCGGACCTTTATCAATGACATCACCACCGACCCC
GACGACGCCGCCATCACCCTCGCCACCATCGAGATGGCGCACACGATGAAGCTGAAGGTGATCGCGGAGGGGGTCGAGAC
CAAGCCCCAGCTCGACTTCCTCACCAAAAACGGCTGCGACATGTACCAGGGTTACCTCTTCAGTAAACCGGTCCCCTCTA
CGGAGCTTCCCCGCCTTTTCAACCGCTGGCAGTAG

Upstream 100 bases:

>100_bases
GCCTGGGGCGCGCGGGGTCGACCGAGGGGGCGGGGGCGCTGCTCGTACAGGTTGAGGAGGAATACCGGTTGGTCAGGGAT
GCCCTTTTGGGAGGACCTTC

Downstream 100 bases:

>100_bases
CCGCACTTCCTCTTCCTGTCTTGCTTAAAAAATAGTCAGCCCTGCCGCGTTAGAGACGGCAACTCCCTTTGCCATGGACC
CCGGTGGAATCTTGATCCAG

Product: response receiver sensor diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MLTRKAKRSTPLVMVVDDDQAVRLLARETLENSGFAVRDVENGEQALEEFDVHAPDIVLLDVMMPGIDGFSVCSAIRRTA
SGRDTPVLMMTGLDDLESIDCAYEAGATDFITKPINWHVLGYRVSYMLRASGALEQLRESRAGLAHAQSLAHIGSWEWDL
VTGEIRCSEEVYSICSIERSFKGGNPILDPVHPLDRGFVQGSIDEAIGKRAPLSFDYRITLGGGERTLHAELVTVLDEQG
EAVCLTGTIQDITERKRAEEQIRLLAYYDALTGLPNRRFFLQQLEQALVFANRYDRMLAVLFLDLDRFKLVNDTLGHGVG
DRLLQDVADRLLRCVRRGDCLARADEECPPSLVSRLGGDEFTIMLSDIEHFQDVAKIARRILEAVSVPYSLEGQEVFVST
SIGISLYPFDATTASDLIRNADGAMYQAKEQGRNGYQIYDESMNAKALERIILESQLHKALKEEEFIVYYQPQVSNQSGR
VVGIEALVRWNSKELGLVEPGRFLPLAEEIGLVIQIDQWVMREACRQHKLWLDAGFPPVTLAINISGQQFMKNELLETVT
SVLKESGLDPGLLELELTEGVLMAHTERTVKTLQALKGMGVRLAIDDFGTGFSSLSYLKRFPLDVLKIDRTFINDITTDP
DDAAITLATIEMAHTMKLKVIAEGVETKPQLDFLTKNGCDMYQGYLFSKPVPSTELPRLFNRWQ

Sequences:

>Translated_704_residues
MLTRKAKRSTPLVMVVDDDQAVRLLARETLENSGFAVRDVENGEQALEEFDVHAPDIVLLDVMMPGIDGFSVCSAIRRTA
SGRDTPVLMMTGLDDLESIDCAYEAGATDFITKPINWHVLGYRVSYMLRASGALEQLRESRAGLAHAQSLAHIGSWEWDL
VTGEIRCSEEVYSICSIERSFKGGNPILDPVHPLDRGFVQGSIDEAIGKRAPLSFDYRITLGGGERTLHAELVTVLDEQG
EAVCLTGTIQDITERKRAEEQIRLLAYYDALTGLPNRRFFLQQLEQALVFANRYDRMLAVLFLDLDRFKLVNDTLGHGVG
DRLLQDVADRLLRCVRRGDCLARADEECPPSLVSRLGGDEFTIMLSDIEHFQDVAKIARRILEAVSVPYSLEGQEVFVST
SIGISLYPFDATTASDLIRNADGAMYQAKEQGRNGYQIYDESMNAKALERIILESQLHKALKEEEFIVYYQPQVSNQSGR
VVGIEALVRWNSKELGLVEPGRFLPLAEEIGLVIQIDQWVMREACRQHKLWLDAGFPPVTLAINISGQQFMKNELLETVT
SVLKESGLDPGLLELELTEGVLMAHTERTVKTLQALKGMGVRLAIDDFGTGFSSLSYLKRFPLDVLKIDRTFINDITTDP
DDAAITLATIEMAHTMKLKVIAEGVETKPQLDFLTKNGCDMYQGYLFSKPVPSTELPRLFNRWQ
>Mature_704_residues
MLTRKAKRSTPLVMVVDDDQAVRLLARETLENSGFAVRDVENGEQALEEFDVHAPDIVLLDVMMPGIDGFSVCSAIRRTA
SGRDTPVLMMTGLDDLESIDCAYEAGATDFITKPINWHVLGYRVSYMLRASGALEQLRESRAGLAHAQSLAHIGSWEWDL
VTGEIRCSEEVYSICSIERSFKGGNPILDPVHPLDRGFVQGSIDEAIGKRAPLSFDYRITLGGGERTLHAELVTVLDEQG
EAVCLTGTIQDITERKRAEEQIRLLAYYDALTGLPNRRFFLQQLEQALVFANRYDRMLAVLFLDLDRFKLVNDTLGHGVG
DRLLQDVADRLLRCVRRGDCLARADEECPPSLVSRLGGDEFTIMLSDIEHFQDVAKIARRILEAVSVPYSLEGQEVFVST
SIGISLYPFDATTASDLIRNADGAMYQAKEQGRNGYQIYDESMNAKALERIILESQLHKALKEEEFIVYYQPQVSNQSGR
VVGIEALVRWNSKELGLVEPGRFLPLAEEIGLVIQIDQWVMREACRQHKLWLDAGFPPVTLAINISGQQFMKNELLETVT
SVLKESGLDPGLLELELTEGVLMAHTERTVKTLQALKGMGVRLAIDDFGTGFSSLSYLKRFPLDVLKIDRTFINDITTDP
DDAAITLATIEMAHTMKLKVIAEGVETKPQLDFLTKNGCDMYQGYLFSKPVPSTELPRLFNRWQ

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=461, Percent_Identity=37.9609544468547, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI87081921, Length=481, Percent_Identity=32.6403326403326, Blast_Score=262, Evalue=6e-71,
Organism=Escherichia coli, GI226510982, Length=459, Percent_Identity=27.4509803921569, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1790496, Length=250, Percent_Identity=32.8, Blast_Score=156, Evalue=5e-39,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=34.4, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI1786507, Length=257, Percent_Identity=31.5175097276265, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1788381, Length=520, Percent_Identity=27.8846153846154, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=31.6, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=32.6612903225806, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=34.9206349206349, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI1787055, Length=246, Percent_Identity=32.520325203252, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=32.7868852459016, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI87082096, Length=262, Percent_Identity=29.0076335877863, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081881, Length=321, Percent_Identity=28.9719626168224, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081977, Length=204, Percent_Identity=31.8627450980392, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI145693134, Length=177, Percent_Identity=33.8983050847458, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789650, Length=454, Percent_Identity=22.2466960352423, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=174, Percent_Identity=35.0574712643678, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787262, Length=182, Percent_Identity=31.8681318681319, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787410, Length=238, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786584, Length=196, Percent_Identity=27.5510204081633, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=35.2380952380952, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789809, Length=166, Percent_Identity=30.1204819277108, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788394, Length=136, Percent_Identity=32.3529411764706, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=32.4786324786325, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788550, Length=147, Percent_Identity=29.9319727891156, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=176, Percent_Identity=34.0909090909091, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787802, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=178, Percent_Identity=28.6516853932584, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786911, Length=121, Percent_Identity=29.7520661157025, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 78721; Mature: 78721

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRKAKRSTPLVMVVDDDQAVRLLARETLENSGFAVRDVENGEQALEEFDVHAPDIVLL
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCEEEE
DVMMPGIDGFSVCSAIRRTASGRDTPVLMMTGLDDLESIDCAYEAGATDFITKPINWHVL
EEHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCHHHHCCCCHHCCCCCCEEEE
GYRVSYMLRASGALEQLRESRAGLAHAQSLAHIGSWEWDLVTGEIRCSEEVYSICSIERS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEECHHHHHHHHHHHHH
FKGGNPILDPVHPLDRGFVQGSIDEAIGKRAPLSFDYRITLGGGERTLHAELVTVLDEQG
CCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHCCC
EAVCLTGTIQDITERKRAEEQIRLLAYYDALTGLPNRRFFLQQLEQALVFANRYDRMLAV
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFLDLDRFKLVNDTLGHGVGDRLLQDVADRLLRCVRRGDCLARADEECPPSLVSRLGGDE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHCCCCE
FTIMLSDIEHFQDVAKIARRILEAVSVPYSLEGQEVFVSTSIGISLYPFDATTASDLIRN
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCHHHHHHHC
ADGAMYQAKEQGRNGYQIYDESMNAKALERIILESQLHKALKEEEFIVYYQPQVSNQSGR
CCCCEEEHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
VVGIEALVRWNSKELGLVEPGRFLPLAEEIGLVIQIDQWVMREACRQHKLWLDAGFPPVT
EEEEEHHEEECCCCCCCCCCCCCCCCHHHCCEEEEEHHHHHHHHHHHCCEEEECCCCCEE
LAINISGQQFMKNELLETVTSVLKESGLDPGLLELELTEGVLMAHTERTVKTLQALKGMG
EEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
VRLAIDDFGTGFSSLSYLKRFPLDVLKIDRTFINDITTDPDDAAITLATIEMAHTMKLKV
EEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHEEEEE
IAEGVETKPQLDFLTKNGCDMYQGYLFSKPVPSTELPRLFNRWQ
EECCCCCCCCCCEECCCCCHHHHCEEECCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLTRKAKRSTPLVMVVDDDQAVRLLARETLENSGFAVRDVENGEQALEEFDVHAPDIVLL
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCEEEE
DVMMPGIDGFSVCSAIRRTASGRDTPVLMMTGLDDLESIDCAYEAGATDFITKPINWHVL
EEHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCHHHHCCCCHHCCCCCCEEEE
GYRVSYMLRASGALEQLRESRAGLAHAQSLAHIGSWEWDLVTGEIRCSEEVYSICSIERS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEECHHHHHHHHHHHHH
FKGGNPILDPVHPLDRGFVQGSIDEAIGKRAPLSFDYRITLGGGERTLHAELVTVLDEQG
CCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCCCEEHHHHHHHHHHCCC
EAVCLTGTIQDITERKRAEEQIRLLAYYDALTGLPNRRFFLQQLEQALVFANRYDRMLAV
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFLDLDRFKLVNDTLGHGVGDRLLQDVADRLLRCVRRGDCLARADEECPPSLVSRLGGDE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHCCCCE
FTIMLSDIEHFQDVAKIARRILEAVSVPYSLEGQEVFVSTSIGISLYPFDATTASDLIRN
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCHHHHHHHC
ADGAMYQAKEQGRNGYQIYDESMNAKALERIILESQLHKALKEEEFIVYYQPQVSNQSGR
CCCCEEEHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
VVGIEALVRWNSKELGLVEPGRFLPLAEEIGLVIQIDQWVMREACRQHKLWLDAGFPPVT
EEEEEHHEEECCCCCCCCCCCCCCCCHHHCCEEEEEHHHHHHHHHHHCCEEEECCCCCEE
LAINISGQQFMKNELLETVTSVLKESGLDPGLLELELTEGVLMAHTERTVKTLQALKGMG
EEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
VRLAIDDFGTGFSSLSYLKRFPLDVLKIDRTFINDITTDPDDAAITLATIEMAHTMKLKV
EEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHEEEEE
IAEGVETKPQLDFLTKNGCDMYQGYLFSKPVPSTELPRLFNRWQ
EECCCCCCCCCCEECCCCCHHHHCEEECCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]