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The map label for this gene is apl-1 [H]

Identifier: 197117812

GI number: 197117812

Start: 1641093

End: 1643072

Strand: Direct

Name: apl-1 [H]

Synonym: Gbem_1424

Alternate gene names: 197117812

Gene position: 1641093-1643072 (Clockwise)

Preceding gene: 197117811

Following gene: 197117813

Centisome position: 35.56

GC content: 62.27

Gene sequence:

>1980_bases
ATGAGATATCTGTTCCTTCCCTTGCTGATGGTACTGATCTTCGGCACCTCCGCGCTTGCAGCCGATGTGTCCGCCCAGGC
GGCCCCAGGCGGCCCCAATGCCGTAGCAGCCGCCGCTGCCAAGGCCCCGCCGGGGCTCGCCGCTTCCCCGCAAGCGCCCG
CTGCAGCGGCGGCCAAGGCTCAGGCACCGGCGCCGGCGCCGGGCGGCAAGAAGATGCAGACCAACCGCACGTTCACCATC
AGCATGTTCCTCTTGATCATCGCGGCGACCGCCGGGATCGTGGTCTGGGCCTCGAAAAGCACCACCACCGCATCCGATTA
TTACGCGGCGGGCGGTGGCATTTCCGGGATTCAGAACGGCTGGGCCATCGCCGGAGATTTCCTCTCCGCCGCGACCTTCC
TCGGGATCACCGGACTCATGTCTCTCTTCGGCCCGGACGGGTTCATGTACTCGGTGGGGATCATCATCAGCTTTCTCACC
ATCCTCCTCATCATCGCCGAACCATGCCGCAATGCCGGCAAGTACACCCTGGGCGACATCCTCGCCTTCCGTTCGTCGTC
CCGGGTAGTGCGGGCTGTCGCGGCCCTTTCCGCCGTGGTGGTTTCCATCTTCTACCTGCTCGGGCAGATGGTGGGGGCCG
GCAAACTGATGCAGCTCCTTTTGGGGATTCCCTACAAGGTCTCGATCATAGGAGTCGGTGCCCTGATCATCGTCTACGTG
GCGCTGGGCGGGATGAAGGCGACCACCTGGGTGCAGATCATCAAGGCCGCGCTCCTCATGTTCACCGGGGTCGTCCTGAG
CGTCGGGATACTCTGGAAGTCGGGATTCAGCCTCTTCGCATTCTTCGACAGCGTGGCGACCAGCCCGCAGATCCAGGATC
ACGTGCGTGGCGTCATGAAGCACCCGGTGGCGCAGCCGGGGTTCGATTACGGCCAGCGCTTCCTGGAGCTGGGGCTTTTC
TTCAAGAACCCGCTGGACCAGGTATCCCTCGGACTTGCGTGGATCCTCGGGGCCGCCGGCCTGCCGCACGTCATGATGCG
GTTTTTCACCGTGCCCAACGCCAAGGAGGCTAGAAAGAGCGTGGTCGCCTCCATGTTCCTGATCGGCCTGTTCCTGATCA
TGGTTTCCTTCCTGGGCTTTGGCGCCGCCCTTTATGTCACCCCGCAGAAGATTATGGCGCTCGACAAGGGGGGCAACATG
GCGGGGCTCATGATCGCGCAGTATATCGGCGGCGGGGCGGGTACCGTCACCGGAGACCTGCTCCTGGCCTTTGTCTGCGC
CGTCGCTTTCGCCACCATACTCGCGGTCGTCTCGGGTCTGGTGCTCGCATCCTCGGCGGCCATCGCCCACGATTTGTACG
TCAACGTCATTAAAAAGGGGAAGGCGGATCAGGGGACACAGATAAAGGTCGCCAGGGTGGCATCGTTTTTCGTCGGCGCC
ATCGCCATCGTGCTCGGCATTGCCTGCGAAAACCTCAACATCGCGCAGCTGGTCGGCCTTGCGCTTGCCGTGGTGGCTTC
GGCGAACTTCCCCGTCCTGATCTTCGCGCTGTTCTGGAAGCGGTTCAATTCAGCCGGGATCATCGCCGGCTTGGTGGTCG
GCACCGTGGTGACCATCGGGATCCTGATGGTTTCGCCGAACATGACCTATCCCAAGAAGGTGGCTGCCGACGCCCAGAAG
GTCGTGCTCGCCTTGGAGAAAAAGCAAAGCGAGGCTGGGGGGCTTTCCGCTGTGGAGTTGAAAACGCTGGAAAAGGCGAA
ATCGGATTACGTGCTGAACAAGGAAGGGACCTCGCTGGTGGGGCTCGACGCGCCGCTATTCCCGCTCAAAAACCCGGGGA
TACTTTCCGTGCCCATCGGGTTCTTCGTTACCATCGCCGCTACCTTTTTGTTCCGCAACCGTCGCGAGGAAGAGATGTTC
GAGGAACTGTTCGTCCGGCAGACCACGGGATACGGCATGGCCAAGGCGGCCAAGCACTGA

Upstream 100 bases:

>100_bases
TGGCCTGGGCCATCGCGATCATCTACACGCGCAAATCCAACCGGGAATTCGATCCCCTTACCACTGAACTGGTCGAGATG
ATCTTGAAGGAGGAATGCCA

Downstream 100 bases:

>100_bases
TGAGTCAAATTCCCCCTCCCGTCAAGGGAGGGGGAATTCGGAAACAGTTTGTAGGGGGGTGGGGGGAGGTAGAGGGAAGG
GGATCTAATCGTCGCGGCGC

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MRYLFLPLLMVLIFGTSALAADVSAQAAPGGPNAVAAAAAKAPPGLAASPQAPAAAAAKAQAPAPAPGGKKMQTNRTFTI
SMFLLIIAATAGIVVWASKSTTTASDYYAAGGGISGIQNGWAIAGDFLSAATFLGITGLMSLFGPDGFMYSVGIIISFLT
ILLIIAEPCRNAGKYTLGDILAFRSSSRVVRAVAALSAVVVSIFYLLGQMVGAGKLMQLLLGIPYKVSIIGVGALIIVYV
ALGGMKATTWVQIIKAALLMFTGVVLSVGILWKSGFSLFAFFDSVATSPQIQDHVRGVMKHPVAQPGFDYGQRFLELGLF
FKNPLDQVSLGLAWILGAAGLPHVMMRFFTVPNAKEARKSVVASMFLIGLFLIMVSFLGFGAALYVTPQKIMALDKGGNM
AGLMIAQYIGGGAGTVTGDLLLAFVCAVAFATILAVVSGLVLASSAAIAHDLYVNVIKKGKADQGTQIKVARVASFFVGA
IAIVLGIACENLNIAQLVGLALAVVASANFPVLIFALFWKRFNSAGIIAGLVVGTVVTIGILMVSPNMTYPKKVAADAQK
VVLALEKKQSEAGGLSAVELKTLEKAKSDYVLNKEGTSLVGLDAPLFPLKNPGILSVPIGFFVTIAATFLFRNRREEEMF
EELFVRQTTGYGMAKAAKH

Sequences:

>Translated_659_residues
MRYLFLPLLMVLIFGTSALAADVSAQAAPGGPNAVAAAAAKAPPGLAASPQAPAAAAAKAQAPAPAPGGKKMQTNRTFTI
SMFLLIIAATAGIVVWASKSTTTASDYYAAGGGISGIQNGWAIAGDFLSAATFLGITGLMSLFGPDGFMYSVGIIISFLT
ILLIIAEPCRNAGKYTLGDILAFRSSSRVVRAVAALSAVVVSIFYLLGQMVGAGKLMQLLLGIPYKVSIIGVGALIIVYV
ALGGMKATTWVQIIKAALLMFTGVVLSVGILWKSGFSLFAFFDSVATSPQIQDHVRGVMKHPVAQPGFDYGQRFLELGLF
FKNPLDQVSLGLAWILGAAGLPHVMMRFFTVPNAKEARKSVVASMFLIGLFLIMVSFLGFGAALYVTPQKIMALDKGGNM
AGLMIAQYIGGGAGTVTGDLLLAFVCAVAFATILAVVSGLVLASSAAIAHDLYVNVIKKGKADQGTQIKVARVASFFVGA
IAIVLGIACENLNIAQLVGLALAVVASANFPVLIFALFWKRFNSAGIIAGLVVGTVVTIGILMVSPNMTYPKKVAADAQK
VVLALEKKQSEAGGLSAVELKTLEKAKSDYVLNKEGTSLVGLDAPLFPLKNPGILSVPIGFFVTIAATFLFRNRREEEMF
EELFVRQTTGYGMAKAAKH
>Mature_659_residues
MRYLFLPLLMVLIFGTSALAADVSAQAAPGGPNAVAAAAAKAPPGLAASPQAPAAAAAKAQAPAPAPGGKKMQTNRTFTI
SMFLLIIAATAGIVVWASKSTTTASDYYAAGGGISGIQNGWAIAGDFLSAATFLGITGLMSLFGPDGFMYSVGIIISFLT
ILLIIAEPCRNAGKYTLGDILAFRSSSRVVRAVAALSAVVVSIFYLLGQMVGAGKLMQLLLGIPYKVSIIGVGALIIVYV
ALGGMKATTWVQIIKAALLMFTGVVLSVGILWKSGFSLFAFFDSVATSPQIQDHVRGVMKHPVAQPGFDYGQRFLELGLF
FKNPLDQVSLGLAWILGAAGLPHVMMRFFTVPNAKEARKSVVASMFLIGLFLIMVSFLGFGAALYVTPQKIMALDKGGNM
AGLMIAQYIGGGAGTVTGDLLLAFVCAVAFATILAVVSGLVLASSAAIAHDLYVNVIKKGKADQGTQIKVARVASFFVGA
IAIVLGIACENLNIAQLVGLALAVVASANFPVLIFALFWKRFNSAGIIAGLVVGTVVTIGILMVSPNMTYPKKVAADAQK
VVLALEKKQSEAGGLSAVELKTLEKAKSDYVLNKEGTSLVGLDAPLFPLKNPGILSVPIGFFVTIAATFLFRNRREEEMF
EELFVRQTTGYGMAKAAKH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=608, Percent_Identity=36.8421052631579, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1787251, Length=473, Percent_Identity=24.5243128964059, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082237, Length=468, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 68783; Mature: 68783

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLFLPLLMVLIFGTSALAADVSAQAAPGGPNAVAAAAAKAPPGLAASPQAPAAAAAKA
CCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHC
QAPAPAPGGKKMQTNRTFTISMFLLIIAATAGIVVWASKSTTTASDYYAAGGGISGIQNG
CCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
WAIAGDFLSAATFLGITGLMSLFGPDGFMYSVGIIISFLTILLIIAEPCRNAGKYTLGDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAFRSSSRVVRAVAALSAVVVSIFYLLGQMVGAGKLMQLLLGIPYKVSIIGVGALIIVYV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEHHHHHHHHHH
ALGGMKATTWVQIIKAALLMFTGVVLSVGILWKSGFSLFAFFDSVATSPQIQDHVRGVMK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHH
HPVAQPGFDYGQRFLELGLFFKNPLDQVSLGLAWILGAAGLPHVMMRFFTVPNAKEARKS
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHH
VVASMFLIGLFLIMVSFLGFGAALYVTPQKIMALDKGGNMAGLMIAQYIGGGAGTVTGDL
HHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHH
LLAFVCAVAFATILAVVSGLVLASSAAIAHDLYVNVIKKGKADQGTQIKVARVASFFVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHH
IAIVLGIACENLNIAQLVGLALAVVASANFPVLIFALFWKRFNSAGIIAGLVVGTVVTIG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ILMVSPNMTYPKKVAADAQKVVLALEKKQSEAGGLSAVELKTLEKAKSDYVLNKEGTSLV
HHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEE
GLDAPLFPLKNPGILSVPIGFFVTIAATFLFRNRREEEMFEELFVRQTTGYGMAKAAKH
ECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure
MRYLFLPLLMVLIFGTSALAADVSAQAAPGGPNAVAAAAAKAPPGLAASPQAPAAAAAKA
CCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHC
QAPAPAPGGKKMQTNRTFTISMFLLIIAATAGIVVWASKSTTTASDYYAAGGGISGIQNG
CCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
WAIAGDFLSAATFLGITGLMSLFGPDGFMYSVGIIISFLTILLIIAEPCRNAGKYTLGDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAFRSSSRVVRAVAALSAVVVSIFYLLGQMVGAGKLMQLLLGIPYKVSIIGVGALIIVYV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEHHHHHHHHHH
ALGGMKATTWVQIIKAALLMFTGVVLSVGILWKSGFSLFAFFDSVATSPQIQDHVRGVMK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHH
HPVAQPGFDYGQRFLELGLFFKNPLDQVSLGLAWILGAAGLPHVMMRFFTVPNAKEARKS
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHH
VVASMFLIGLFLIMVSFLGFGAALYVTPQKIMALDKGGNMAGLMIAQYIGGGAGTVTGDL
HHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHH
LLAFVCAVAFATILAVVSGLVLASSAAIAHDLYVNVIKKGKADQGTQIKVARVASFFVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHH
IAIVLGIACENLNIAQLVGLALAVVASANFPVLIFALFWKRFNSAGIIAGLVVGTVVTIG
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ILMVSPNMTYPKKVAADAQKVVLALEKKQSEAGGLSAVELKTLEKAKSDYVLNKEGTSLV
HHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEE
GLDAPLFPLKNPGILSVPIGFFVTIAATFLFRNRREEEMFEELFVRQTTGYGMAKAAKH
ECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]