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The map label for this gene is moeB [H]

Identifier: 197117738

GI number: 197117738

Start: 1556663

End: 1557517

Strand: Reverse

Name: moeB [H]

Synonym: Gbem_1350

Alternate gene names: 197117738

Gene position: 1557517-1556663 (Counterclockwise)

Preceding gene: 197117739

Following gene: 197117737

Centisome position: 33.75

GC content: 64.09

Gene sequence:

>855_bases
ATGCTCAAAGCTGTCACCTTTCTCAAGGAATCCACCCAAGCGGGGATGCTCTCCTGGAGCGCGCAGAGCCAGGCCGTGGC
CCGGTTCGGCCTGAGGTACCACGAGGTCGAGGCGCTGGCCCTGGAAAACGGGATCTTCCCGGCACGCTACCAGCGCAACC
GGAACATGATCTCGATCGAGGAGCAGCTGAAGCTTTTCCGTAGCCGCGTGGCGGTGATCGGCTGCGGGGGGCTCGGAGGG
TACGTCATCGAAGAGCTGGCCCGCATCGGCGTCGGCCATATCGTGGCCATTGACCCCGATATCTTCGAGGAGCACAACCT
GAACCGCCAGATCCTTTCCACCCCGGCGACGCTCGGCAAGGCCAAGGTTGAGGCCGCCGTCGACCGTGTGGCCGAGATCA
ACCCCGCCGTCACGGTTACCCCCATCAAGGACTACTTCTGCCTCGCCAACGGCTCCGAGCAACTGGCCGGCGCCATGGTA
GCGGTCGATGCCCTCGACAGCATCCCCTACCGGTTGGAACTGGCAGAATTTTGCACCGTGGCAGGGATACCGATGGTCCA
CGGCGCCATCGGCGGCTGGTACGGCCACGTGGCGACCCAGCTTCCCGGCGACACCACGGTGCAGAGCATCTACCGCCACT
GGGTAGCGGGAAAAGGTATCGAGCAGCAATTGGGAAACCCCGCCTTCACCCCGGCCGTGGTGGCGAGCCTGGAGGTGGCC
GAGGCCTGCAAGATCCTCCTCGGCAAAGGGGAGCTTTTGCGCGACCGCAAGTTGAGCATCGACCTGCTGGAGATGGAGGT
TCACGAGATCTCCTACCCGAAGGTGCCCCCGGTCGAACTGGTCGTCGCGGCATAA

Upstream 100 bases:

>100_bases
ATCGGCATCGTCATGCTGAACGGCAGGCACGGGGAACTCGACTCCAAACTCTCCGACCACGACACCCTTTCACTGTTTCC
ATTGGTAGGAGGAGGCTAAC

Downstream 100 bases:

>100_bases
TGCGGCGCGGGCTGCATAACCTGGCCGGGGGCAACCGGTCAAAGTCCCCCCTCCCCTTGCGGGAGGCTCTTCCGGGATTT
GCGGGGATAACAGCCCCCCC

Product: molybdopterin biosynthesis sulfur carrier protein sulfurylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLKAVTFLKESTQAGMLSWSAQSQAVARFGLRYHEVEALALENGIFPARYQRNRNMISIEEQLKLFRSRVAVIGCGGLGG
YVIEELARIGVGHIVAIDPDIFEEHNLNRQILSTPATLGKAKVEAAVDRVAEINPAVTVTPIKDYFCLANGSEQLAGAMV
AVDALDSIPYRLELAEFCTVAGIPMVHGAIGGWYGHVATQLPGDTTVQSIYRHWVAGKGIEQQLGNPAFTPAVVASLEVA
EACKILLGKGELLRDRKLSIDLLEMEVHEISYPKVPPVELVVAA

Sequences:

>Translated_284_residues
MLKAVTFLKESTQAGMLSWSAQSQAVARFGLRYHEVEALALENGIFPARYQRNRNMISIEEQLKLFRSRVAVIGCGGLGG
YVIEELARIGVGHIVAIDPDIFEEHNLNRQILSTPATLGKAKVEAAVDRVAEINPAVTVTPIKDYFCLANGSEQLAGAMV
AVDALDSIPYRLELAEFCTVAGIPMVHGAIGGWYGHVATQLPGDTTVQSIYRHWVAGKGIEQQLGNPAFTPAVVASLEVA
EACKILLGKGELLRDRKLSIDLLEMEVHEISYPKVPPVELVVAA
>Mature_284_residues
MLKAVTFLKESTQAGMLSWSAQSQAVARFGLRYHEVEALALENGIFPARYQRNRNMISIEEQLKLFRSRVAVIGCGGLGG
YVIEELARIGVGHIVAIDPDIFEEHNLNRQILSTPATLGKAKVEAAVDRVAEINPAVTVTPIKDYFCLANGSEQLAGAMV
AVDALDSIPYRLELAEFCTVAGIPMVHGAIGGWYGHVATQLPGDTTVQSIYRHWVAGKGIEQQLGNPAFTPAVVASLEVA
EACKILLGKGELLRDRKLSIDLLEMEVHEISYPKVPPVELVVAA

Specific function: Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad). [C]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=151, Percent_Identity=31.1258278145695, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4885649, Length=132, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787048, Length=239, Percent_Identity=29.7071129707113, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789177, Length=136, Percent_Identity=36.0294117647059, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082356, Length=156, Percent_Identity=30.1282051282051, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203301, Length=147, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582879, Length=230, Percent_Identity=29.5652173913043, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 30757; Mature: 30757

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAVTFLKESTQAGMLSWSAQSQAVARFGLRYHEVEALALENGIFPARYQRNRNMISIE
CCHHHHHHHHCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCEEEHH
EQLKLFRSRVAVIGCGGLGGYVIEELARIGVGHIVAIDPDIFEEHNLNRQILSTPATLGK
HHHHHHHHHEEEEEECCCHHHHHHHHHHCCCCEEEEECCHHHHHCCCCHHHHCCCHHHHH
AKVEAAVDRVAEINPAVTVTPIKDYFCLANGSEQLAGAMVAVDALDSIPYRLELAEFCTV
HHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHH
AGIPMVHGAIGGWYGHVATQLPGDTTVQSIYRHWVAGKGIEQQLGNPAFTPAVVASLEVA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHH
EACKILLGKGELLRDRKLSIDLLEMEVHEISYPKVPPVELVVAA
HHHHHHHCCCHHHHCCCCCEEHEEEHHHHCCCCCCCCEEEEEEC
>Mature Secondary Structure
MLKAVTFLKESTQAGMLSWSAQSQAVARFGLRYHEVEALALENGIFPARYQRNRNMISIE
CCHHHHHHHHCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCEEEHH
EQLKLFRSRVAVIGCGGLGGYVIEELARIGVGHIVAIDPDIFEEHNLNRQILSTPATLGK
HHHHHHHHHEEEEEECCCHHHHHHHHHHCCCCEEEEECCHHHHHCCCCHHHHCCCHHHHH
AKVEAAVDRVAEINPAVTVTPIKDYFCLANGSEQLAGAMVAVDALDSIPYRLELAEFCTV
HHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHH
AGIPMVHGAIGGWYGHVATQLPGDTTVQSIYRHWVAGKGIEQQLGNPAFTPAVVASLEVA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHH
EACKILLGKGELLRDRKLSIDLLEMEVHEISYPKVPPVELVVAA
HHHHHHHCCCHHHHCCCCCEEHEEEHHHHCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA