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The map label for this gene is nrnA [H]

Identifier: 197117693

GI number: 197117693

Start: 1508499

End: 1509467

Strand: Direct

Name: nrnA [H]

Synonym: Gbem_1305

Alternate gene names: 197117693

Gene position: 1508499-1509467 (Clockwise)

Preceding gene: 197117692

Following gene: 197117694

Centisome position: 32.69

GC content: 63.57

Gene sequence:

>969_bases
ATGACGGCGAGCAAAGCTGAGATAACCCGGATACTGGCGGAGATCGACAACGGCTCCAGCTTCCTGATCACCAGCCACGA
GAGCCCCGACCCGGACGCGGTCGGCTCGTCGCTTGCCCTTGCCAACTACCTCTCCGGGCGCGGCAAGGACGTCACCGTGT
ACCTGAGCGATCCGGTCCCGGACAACTGCTCCTTCCTCCCCATGGCGGATCAGGTCTATGCGGAAATGCCGGAGCGCGAC
TTCGACGTCTGCTTCGTCCTCGACGTGGGGGAGTTCCGCAGGGCCGGTAAGGCGGTCACCGGCAACAAGAGGATCGGCCG
CCTCATCAACATCGACCACCACTTGGGGTGCGAGAACTTCGGCGTCTGCAACCTGATCGATCCCAAGGCGAGCGCCACCG
CGGCGCTCATCCACCGGATCATCAAGGCGGCCGGCGACGAGGTCGATTATCCCGCCGCCCTTTGCATCTACACCGCCATC
CTTTCCGACACCGGGAGCTTCCACTACTCGAACTCCGACCCCGAGGCGTTCGCCATCGCCGGCGAGATGATCGACAAGGG
GGTCAACGCTTGGGATGTGAACGAGAACCTCTACGAGAGCGAGCCGCTGCAGCGTATCGCGCTCCTCGCTCTGGCGCTTT
CCGATCTCACCGTCTCCCCTTCCGGGGAATACGCCTCGGTCACCGTCACTCTCGACATGTACGAGAAGACCGGCGCCAAC
GCCCAGGACACCGACCGTTTCATCAACTACCCCCGCTCCATCAGGGGAGTGCAGGTGGCGCTCTTCTTCCGCCAGATCGA
GGAAGGCCTATTCAAGGTCGGCTTCAGGTCCAAGGGGAAGATGGACGTCTCCGCCGTGTCCGCCTCTTTTGGCGGGGGCG
GGCATCATAACGCCGCCGGCTGCACGGTCAAGGGGACTTTGGCCGAGGTGAAGGCCCTGGTCTTCGACCGACTGGAGCAG
ATGCGCTGA

Upstream 100 bases:

>100_bases
CTCAAGATGCGCTTTGTCCCCGAGGTCCTGTTCAAGTACGACACATCCCTGGATTACGGCCAGCATATCGAATCGATTCT
GAAGGAGATAGGGGCAACGG

Downstream 100 bases:

>100_bases
TGCTGAACGGCTTTTTTGTGATCGACAAGCCGGCCGGTGTCACCTCGCATGACATCGTGTCCAAGGTGCGTCGCGCCATC
AACCAGAAAAAAGTGGGGCA

Product: phosphoesterase

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTASKAEITRILAEIDNGSSFLITSHESPDPDAVGSSLALANYLSGRGKDVTVYLSDPVPDNCSFLPMADQVYAEMPERD
FDVCFVLDVGEFRRAGKAVTGNKRIGRLINIDHHLGCENFGVCNLIDPKASATAALIHRIIKAAGDEVDYPAALCIYTAI
LSDTGSFHYSNSDPEAFAIAGEMIDKGVNAWDVNENLYESEPLQRIALLALALSDLTVSPSGEYASVTVTLDMYEKTGAN
AQDTDRFINYPRSIRGVQVALFFRQIEEGLFKVGFRSKGKMDVSAVSASFGGGGHHNAAGCTVKGTLAEVKALVFDRLEQ
MR

Sequences:

>Translated_322_residues
MTASKAEITRILAEIDNGSSFLITSHESPDPDAVGSSLALANYLSGRGKDVTVYLSDPVPDNCSFLPMADQVYAEMPERD
FDVCFVLDVGEFRRAGKAVTGNKRIGRLINIDHHLGCENFGVCNLIDPKASATAALIHRIIKAAGDEVDYPAALCIYTAI
LSDTGSFHYSNSDPEAFAIAGEMIDKGVNAWDVNENLYESEPLQRIALLALALSDLTVSPSGEYASVTVTLDMYEKTGAN
AQDTDRFINYPRSIRGVQVALFFRQIEEGLFKVGFRSKGKMDVSAVSASFGGGGHHNAAGCTVKGTLAEVKALVFDRLEQ
MR
>Mature_321_residues
TASKAEITRILAEIDNGSSFLITSHESPDPDAVGSSLALANYLSGRGKDVTVYLSDPVPDNCSFLPMADQVYAEMPERDF
DVCFVLDVGEFRRAGKAVTGNKRIGRLINIDHHLGCENFGVCNLIDPKASATAALIHRIIKAAGDEVDYPAALCIYTAIL
SDTGSFHYSNSDPEAFAIAGEMIDKGVNAWDVNENLYESEPLQRIALLALALSDLTVSPSGEYASVTVTLDMYEKTGANA
QDTDRFINYPRSIRGVQVALFFRQIEEGLFKVGFRSKGKMDVSAVSASFGGGGHHNAAGCTVKGTLAEVKALVFDRLEQM
R

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34774; Mature: 34642

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASKAEITRILAEIDNGSSFLITSHESPDPDAVGSSLALANYLSGRGKDVTVYLSDPVP
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCHHHHHHHHHCCCCCEEEEEECCCCC
DNCSFLPMADQVYAEMPERDFDVCFVLDVGEFRRAGKAVTGNKRIGRLINIDHHLGCENF
CCCCCCCCHHHHHHHCCCCCCCEEEEEECHHHHHCCCCCCCCCCCCEEEECHHHCCCCCC
GVCNLIDPKASATAALIHRIIKAAGDEVDYPAALCIYTAILSDTGSFHYSNSDPEAFAIA
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCHHHEE
GEMIDKGVNAWDVNENLYESEPLQRIALLALALSDLTVSPSGEYASVTVTLDMYEKTGAN
HHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCEECCCCCEEEEEEEEEEHHHCCCC
AQDTDRFINYPRSIRGVQVALFFRQIEEGLFKVGFRSKGKMDVSAVSASFGGGGHHNAAG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCCCCCCC
CTVKGTLAEVKALVFDRLEQMR
CEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TASKAEITRILAEIDNGSSFLITSHESPDPDAVGSSLALANYLSGRGKDVTVYLSDPVP
CCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCHHHHHHHHHCCCCCEEEEEECCCCC
DNCSFLPMADQVYAEMPERDFDVCFVLDVGEFRRAGKAVTGNKRIGRLINIDHHLGCENF
CCCCCCCCHHHHHHHCCCCCCCEEEEEECHHHHHCCCCCCCCCCCCEEEECHHHCCCCCC
GVCNLIDPKASATAALIHRIIKAAGDEVDYPAALCIYTAILSDTGSFHYSNSDPEAFAIA
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCHHHEE
GEMIDKGVNAWDVNENLYESEPLQRIALLALALSDLTVSPSGEYASVTVTLDMYEKTGAN
HHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCEECCCCCEEEEEEEEEEHHHCCCC
AQDTDRFINYPRSIRGVQVALFFRQIEEGLFKVGFRSKGKMDVSAVSASFGGGGHHNAAG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCCCCCCC
CTVKGTLAEVKALVFDRLEQMR
CEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]