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The map label for this gene is norB [H]

Identifier: 197117636

GI number: 197117636

Start: 1443499

End: 1444872

Strand: Reverse

Name: norB [H]

Synonym: Gbem_1248

Alternate gene names: 197117636

Gene position: 1444872-1443499 (Counterclockwise)

Preceding gene: 197117637

Following gene: 308535227

Centisome position: 31.31

GC content: 59.61

Gene sequence:

>1374_bases
ATGAAGACGATCGAATTCGAGAGCCAGCGCGTCTCGCTTTGGTACTTCCGTCTGGCCCTGGTGCTGTTCATCCTGCAGGT
CATCATGGGGCTTTGGCTCTCCATCAACTACGCCTTCACGCTGCCGCAGGAGCTGGTCAACGTCTTTCCCTTCAGCACCG
CCCGTGAAATCCACACCAACACCCTGGTGGCCTGGATGCTGCTCGGCTTCATGGGGGGGACCTACTACATACTCCCGCCC
GAGTGCGACCGCGAGCTTTACAGCACGAAGATCGCCTACTTGCAGTTGATCATCTTCGTGGCAGCGGCGGTCACCGCCGT
GATCGGCTTTTTATTCGGTTGGACCCGCGGGAAGCCGCTTTTGGAGATCCCCTTCCCGCTGAACGCCCTCATCGTGGTGG
CGGCGCTCCTATTCATAGCCAACGTCGCCATGACCATCATCAAGGCGAAGGTGAAGACCGCGCTGCAGTGGATGCTTTTG
GGCGGGGTCACCTTTCTGGCGCTCATGTACCTCTTCGGCATGCCTTTTTACCGCAACCTCAACACGGATTATTACTACTG
GTGGTGGGTGATCCATCTCTGGGTGGAGGGGGCTTGGGAAATAGTCACCGCATCGATCATGGCGTACATCATCATGCGGG
TGACCGGGGTGGAGCGCCAGGTAGTGGAGAAATGGCTCTACGTCGAGACCGGGCTTTTCCTCTTCACCGGCATAGTGGGG
ACCGGCCATCACTACTACTGGATCGGGGCTCCGGACTACTGGCTTTGGTGGGGCGGCATCTTCAGCGCCCTGGAACCGCT
TCCCATCGTGCTCATGGTGGTCGACACCTGGATGCACGTTCGGGAGCGCCGCAACCCCATCGTCAATCCGCTCACCTGGT
ACTACATCGTGGGGCTTGCCATCTACCACCTGGTCGGCGCCGGGCTCTGGGGATTCATGCACACCCTGCCACCCGTCAAC
CGCTACACCCATGGTAGCCAGATCACCGTCTCCCACGGGCATCTCGCCTTTTTCGGTGCTTATGCCCTGTTGAACCTGAC
CATCTTCTACTTCGCCATGCCGCGCCTGAAGGGGATCACGAAGTACCACGACACCGCCGGCCGGTGGGGGTTCTGGATCA
CCACCATCGCCATGTTCACGCTGGGGCTCGTCTTCGGCATAGCCGGGATATTGCAGACCTACCTGGAGCGATTCCTCGAC
ATAGGCTACAGCACCGCCCAGCAGACCATGATGCTCTGGTTCAGGATCGCCTTCGGCGTCGGGCTCGTCTTTTTGGGTGG
CGTACTCACCACCATCTGGCACCTGTTCACGCTGAAGCCTTCCGACAAGCAGGCCGCCGAGGAGGTAGTCGTCACCCCGG
CAGCGAATATTTAA

Upstream 100 bases:

>100_bases
GGCCGGGTGTGACCATGCCGCCGCAGGATGTGAGCCTGCAGACTGCCGGCACCATCGCGGATTTCTTGCTGAGCCTTAAA
AGCCACAAGGAGGTGAGCCA

Downstream 100 bases:

>100_bases
TCATCAAATAATCCTGCGAACGCTGACGCGCCCTTCAGTTGTCCATCCCCTCGCCCCTCTGGGCCTTCGCCCACCGTAGG
CTACGGTCCACAGGTGGGAG

Product: heme-copper oxidase subunit I superfamily protein

Products: NA

Alternate protein names: NOR large subunit; Nitric oxide reductase cytochrome b subunit [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKTIEFESQRVSLWYFRLALVLFILQVIMGLWLSINYAFTLPQELVNVFPFSTAREIHTNTLVAWMLLGFMGGTYYILPP
ECDRELYSTKIAYLQLIIFVAAAVTAVIGFLFGWTRGKPLLEIPFPLNALIVVAALLFIANVAMTIIKAKVKTALQWMLL
GGVTFLALMYLFGMPFYRNLNTDYYYWWWVIHLWVEGAWEIVTASIMAYIIMRVTGVERQVVEKWLYVETGLFLFTGIVG
TGHHYYWIGAPDYWLWWGGIFSALEPLPIVLMVVDTWMHVRERRNPIVNPLTWYYIVGLAIYHLVGAGLWGFMHTLPPVN
RYTHGSQITVSHGHLAFFGAYALLNLTIFYFAMPRLKGITKYHDTAGRWGFWITTIAMFTLGLVFGIAGILQTYLERFLD
IGYSTAQQTMMLWFRIAFGVGLVFLGGVLTTIWHLFTLKPSDKQAAEEVVVTPAANI

Sequences:

>Translated_457_residues
MKTIEFESQRVSLWYFRLALVLFILQVIMGLWLSINYAFTLPQELVNVFPFSTAREIHTNTLVAWMLLGFMGGTYYILPP
ECDRELYSTKIAYLQLIIFVAAAVTAVIGFLFGWTRGKPLLEIPFPLNALIVVAALLFIANVAMTIIKAKVKTALQWMLL
GGVTFLALMYLFGMPFYRNLNTDYYYWWWVIHLWVEGAWEIVTASIMAYIIMRVTGVERQVVEKWLYVETGLFLFTGIVG
TGHHYYWIGAPDYWLWWGGIFSALEPLPIVLMVVDTWMHVRERRNPIVNPLTWYYIVGLAIYHLVGAGLWGFMHTLPPVN
RYTHGSQITVSHGHLAFFGAYALLNLTIFYFAMPRLKGITKYHDTAGRWGFWITTIAMFTLGLVFGIAGILQTYLERFLD
IGYSTAQQTMMLWFRIAFGVGLVFLGGVLTTIWHLFTLKPSDKQAAEEVVVTPAANI
>Mature_457_residues
MKTIEFESQRVSLWYFRLALVLFILQVIMGLWLSINYAFTLPQELVNVFPFSTAREIHTNTLVAWMLLGFMGGTYYILPP
ECDRELYSTKIAYLQLIIFVAAAVTAVIGFLFGWTRGKPLLEIPFPLNALIVVAALLFIANVAMTIIKAKVKTALQWMLL
GGVTFLALMYLFGMPFYRNLNTDYYYWWWVIHLWVEGAWEIVTASIMAYIIMRVTGVERQVVEKWLYVETGLFLFTGIVG
TGHHYYWIGAPDYWLWWGGIFSALEPLPIVLMVVDTWMHVRERRNPIVNPLTWYYIVGLAIYHLVGAGLWGFMHTLPPVN
RYTHGSQITVSHGHLAFFGAYALLNLTIFYFAMPRLKGITKYHDTAGRWGFWITTIAMFTLGLVFGIAGILQTYLERFLD
IGYSTAQQTMMLWFRIAFGVGLVFLGGVLTTIWHLFTLKPSDKQAAEEVVVTPAANI

Specific function: Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen red

COG id: COG3256

COG function: function code P; Nitric oxide reductase large subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.7.99.7 [H]

Molecular weight: Translated: 52354; Mature: 52354

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIEFESQRVSLWYFRLALVLFILQVIMGLWLSINYAFTLPQELVNVFPFSTAREIHTN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCCCHHHHHHHH
TLVAWMLLGFMGGTYYILPPECDRELYSTKIAYLQLIIFVAAAVTAVIGFLFGWTRGKPL
HHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LEIPFPLNALIVVAALLFIANVAMTIIKAKVKTALQWMLLGGVTFLALMYLFGMPFYRNL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
NTDYYYWWWVIHLWVEGAWEIVTASIMAYIIMRVTGVERQVVEKWLYVETGLFLFTGIVG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
TGHHYYWIGAPDYWLWWGGIFSALEPLPIVLMVVDTWMHVRERRNPIVNPLTWYYIVGLA
CCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IYHLVGAGLWGFMHTLPPVNRYTHGSQITVSHGHLAFFGAYALLNLTIFYFAMPRLKGIT
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHH
KYHDTAGRWGFWITTIAMFTLGLVFGIAGILQTYLERFLDIGYSTAQQTMMLWFRIAFGV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GLVFLGGVLTTIWHLFTLKPSDKQAAEEVVVTPAANI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCCC
>Mature Secondary Structure
MKTIEFESQRVSLWYFRLALVLFILQVIMGLWLSINYAFTLPQELVNVFPFSTAREIHTN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCCCHHHHHHHH
TLVAWMLLGFMGGTYYILPPECDRELYSTKIAYLQLIIFVAAAVTAVIGFLFGWTRGKPL
HHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LEIPFPLNALIVVAALLFIANVAMTIIKAKVKTALQWMLLGGVTFLALMYLFGMPFYRNL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
NTDYYYWWWVIHLWVEGAWEIVTASIMAYIIMRVTGVERQVVEKWLYVETGLFLFTGIVG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
TGHHYYWIGAPDYWLWWGGIFSALEPLPIVLMVVDTWMHVRERRNPIVNPLTWYYIVGLA
CCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IYHLVGAGLWGFMHTLPPVNRYTHGSQITVSHGHLAFFGAYALLNLTIFYFAMPRLKGIT
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHH
KYHDTAGRWGFWITTIAMFTLGLVFGIAGILQTYLERFLDIGYSTAQQTMMLWFRIAFGV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GLVFLGGVLTTIWHLFTLKPSDKQAAEEVVVTPAANI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7711073; 10984043 [H]