Click here to switch to the map view.

The map label for this gene is cph2 [H]

Identifier: 197117616

GI number: 197117616

Start: 1424938

End: 1425987

Strand: Direct

Name: cph2 [H]

Synonym: Gbem_1228

Alternate gene names: 197117616

Gene position: 1424938-1425987 (Clockwise)

Preceding gene: 197117615

Following gene: 197117627

Centisome position: 30.88

GC content: 63.24

Gene sequence:

>1050_bases
ATGAGCAGCGGAAATGAAAGCTTGCGGCAGAAGATCCTGATCGTCGACGACACGCCGGCCAACATCGAGATCCTTTACAG
CATCCTCAAAGGGGCGTACGACGTCCTTTTCGCCAAGAACGGGGGTGACGCCATCCGCATCGTGCAGCAGCAGTTGCCGG
ACCTGATCCTTTTGGACATCATGATGCCGGGGATGGACGGCTACCAGGTCTGCCGGGTGCTCAAGGCGGACCCGCTGACC
GCAAAGATCCCGATCATCTTCGTCACCGCCATGAGTAAGGAGGAGGACGAGGCCATGGGGCTGCAGTCAGGGGCCATTGA
CTACCTCACCAAGCCGATAAGCCCGCCCATCGTGCTGGCCAGGGTGAGAAACCACCTGCAGCTCAAGCGGAACTCGGACC
TCTTGGAGCAGCTCACCGCGCAACTGGAGGAGAAGAACCGGGCGCTGGAGGTGCTGGCCCGGGTCGATGGCCTGACCGGC
GTCGCCAACCGCAGGCACTTCGACGAGACACTGCGGCTGGAGGTGCAGCGCGCCATGCGCAACGGGCGTTACCTCTCCCT
TATCCTGTGCGATATCGATTTCTTCAAGAATTACAACGACCATTACGGGCACGTGGCCGGGGACAAATGCCTGCAGTCCT
TCGGGGAACTGCTCCAGGGAAGCTTCAAGAGGGCGGGGGAGGTGCCGGCGCGCTACGGCGGCGAGGAGTTCGCCGTCGTG
CTCCCGGACAGCAGGCCGGAAATTGCCGAGGGGCTTGGGGAGCGGCTGCGTCGGATGCTGCAGGAAAAGGCGCTGCCGCA
CGAGGCGTCGGAGCTGGGGGTGGTGACCGTAAGCGTCGGTGTGTCGGGAGGGCTCGTGGCGCGGGGCCAGGACGCCGAGT
GGTTCATCAAGGAAGCTGACCGGGCGCTGTACCTTGCCAAGTCCGGAGGAAGAAACAGGGTCGCCCTATCTTCCCAATGC
GCGCCAGAGTCCGGCGATTCCCATGAGGGCTACGGCGACCCCTGCGAGCCGGAGCATGACCTGGTGAAGCTTACCGGATA
TGGCGCTTGA

Upstream 100 bases:

>100_bases
GAGAACTCGCGGACCGGCTCGAAGCGACGCTGCAGTCGCTCGATTTCGGCGATGCCGGCACCATCCTGCGGGACATCATG
CAAAACCTGGAGATATCGTA

Downstream 100 bases:

>100_bases
CGCGGTGCCGAAGCCGAGCATGACGGGAATCGTTCCCGCTCCCAGGGCCGCCATGGTGGCGGCGCCGGTCAGTGCGCTGC
CGGTTCCCGCCGCGGCCACG

Product: response receiver-modulated diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSSGNESLRQKILIVDDTPANIEILYSILKGAYDVLFAKNGGDAIRIVQQQLPDLILLDIMMPGMDGYQVCRVLKADPLT
AKIPIIFVTAMSKEEDEAMGLQSGAIDYLTKPISPPIVLARVRNHLQLKRNSDLLEQLTAQLEEKNRALEVLARVDGLTG
VANRRHFDETLRLEVQRAMRNGRYLSLILCDIDFFKNYNDHYGHVAGDKCLQSFGELLQGSFKRAGEVPARYGGEEFAVV
LPDSRPEIAEGLGERLRRMLQEKALPHEASELGVVTVSVGVSGGLVARGQDAEWFIKEADRALYLAKSGGRNRVALSSQC
APESGDSHEGYGDPCEPEHDLVKLTGYGA

Sequences:

>Translated_349_residues
MSSGNESLRQKILIVDDTPANIEILYSILKGAYDVLFAKNGGDAIRIVQQQLPDLILLDIMMPGMDGYQVCRVLKADPLT
AKIPIIFVTAMSKEEDEAMGLQSGAIDYLTKPISPPIVLARVRNHLQLKRNSDLLEQLTAQLEEKNRALEVLARVDGLTG
VANRRHFDETLRLEVQRAMRNGRYLSLILCDIDFFKNYNDHYGHVAGDKCLQSFGELLQGSFKRAGEVPARYGGEEFAVV
LPDSRPEIAEGLGERLRRMLQEKALPHEASELGVVTVSVGVSGGLVARGQDAEWFIKEADRALYLAKSGGRNRVALSSQC
APESGDSHEGYGDPCEPEHDLVKLTGYGA
>Mature_348_residues
SSGNESLRQKILIVDDTPANIEILYSILKGAYDVLFAKNGGDAIRIVQQQLPDLILLDIMMPGMDGYQVCRVLKADPLTA
KIPIIFVTAMSKEEDEAMGLQSGAIDYLTKPISPPIVLARVRNHLQLKRNSDLLEQLTAQLEEKNRALEVLARVDGLTGV
ANRRHFDETLRLEVQRAMRNGRYLSLILCDIDFFKNYNDHYGHVAGDKCLQSFGELLQGSFKRAGEVPARYGGEEFAVVL
PDSRPEIAEGLGERLRRMLQEKALPHEASELGVVTVSVGVSGGLVARGQDAEWFIKEADRALYLAKSGGRNRVALSSQCA
PESGDSHEGYGDPCEPEHDLVKLTGYGA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=36.8131868131868, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787816, Length=201, Percent_Identity=35.8208955223881, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=170, Percent_Identity=38.2352941176471, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787802, Length=180, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693134, Length=196, Percent_Identity=32.6530612244898, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=36.2637362637363, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788381, Length=186, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788394, Length=132, Percent_Identity=40.1515151515151, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786599, Length=115, Percent_Identity=36.5217391304348, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787262, Length=180, Percent_Identity=33.8888888888889, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790860, Length=120, Percent_Identity=35, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790437, Length=103, Percent_Identity=39.8058252427184, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787541, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081974, Length=160, Percent_Identity=29.375, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=36.8852459016393, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=40.3361344537815, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081977, Length=178, Percent_Identity=32.0224719101124, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=34.7107438016529, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789149, Length=109, Percent_Identity=35.7798165137615, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=29.7619047619048, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=118, Percent_Identity=36.4406779661017, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=108, Percent_Identity=34.2592592592593, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 38420; Mature: 38289

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGNESLRQKILIVDDTPANIEILYSILKGAYDVLFAKNGGDAIRIVQQQLPDLILLDI
CCCCCCHHHCEEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHEEHHH
MMPGMDGYQVCRVLKADPLTAKIPIIFVTAMSKEEDEAMGLQSGAIDYLTKPISPPIVLA
HCCCCCHHHHHHHHCCCCCEEECCEEEEEECCCCHHHHHCCCCCCHHHHHCCCCCHHHHH
RVRNHLQLKRNSDLLEQLTAQLEEKNRALEVLARVDGLTGVANRRHFDETLRLEVQRAMR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
NGRYLSLILCDIDFFKNYNDHYGHVAGDKCLQSFGELLQGSFKRAGEVPARYGGEEFAVV
CCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEE
LPDSRPEIAEGLGERLRRMLQEKALPHEASELGVVTVSVGVSGGLVARGQDAEWFIKEAD
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEEECCCCCEEECCCCHHHHHHHCC
RALYLAKSGGRNRVALSSQCAPESGDSHEGYGDPCEPEHDLVKLTGYGA
CEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
SSGNESLRQKILIVDDTPANIEILYSILKGAYDVLFAKNGGDAIRIVQQQLPDLILLDI
CCCCCHHHCEEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHEEHHH
MMPGMDGYQVCRVLKADPLTAKIPIIFVTAMSKEEDEAMGLQSGAIDYLTKPISPPIVLA
HCCCCCHHHHHHHHCCCCCEEECCEEEEEECCCCHHHHHCCCCCCHHHHHCCCCCHHHHH
RVRNHLQLKRNSDLLEQLTAQLEEKNRALEVLARVDGLTGVANRRHFDETLRLEVQRAMR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
NGRYLSLILCDIDFFKNYNDHYGHVAGDKCLQSFGELLQGSFKRAGEVPARYGGEEFAVV
CCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEE
LPDSRPEIAEGLGERLRRMLQEKALPHEASELGVVTVSVGVSGGLVARGQDAEWFIKEAD
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCEEEEEEECCCCCEEECCCCHHHHHHHCC
RALYLAKSGGRNRVALSSQCAPESGDSHEGYGDPCEPEHDLVKLTGYGA
CEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]