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The map label for this gene is yrrC [H]

Identifier: 197117609

GI number: 197117609

Start: 1414186

End: 1416381

Strand: Direct

Name: yrrC [H]

Synonym: Gbem_1221

Alternate gene names: 197117609

Gene position: 1414186-1416381 (Clockwise)

Preceding gene: 197117608

Following gene: 197117610

Centisome position: 30.64

GC content: 64.85

Gene sequence:

>2196_bases
ATGAAAGAGACACCCCCAACAGAAAACGTCGACAGGCTCTCCGGATCGCTGGAGCGCGTCACCTTTCACAGCGAGGAGAC
CGGGTTTTGCGTGCTGCGGGTGAAGGTTGCCGGGCAGCGCGACCTGGTGACGGTGACGGGCGCCGCGGCCTCGGTTACGC
CGGGGGAGTACCTTGAGTGCACCGGCTCCTGGCACAACGACCGGACCCACGGCATGCAGTTCAAGGCCGGGCACATCAAG
GTGGTTCCCCCCACCACGCTGGAAGGGATCGAGAAGTACCTGGGTAGCGGCATGGTGCACGGCATCGGGGCCCACTTCGC
CAAGGTGCTGGTGAAATCGTTCGGCGCGGCGGTCTTCGACGTCATAGAGAACCACCCGGAGAGGCTCCTGGAACTCCCGG
GGATCGGCCGCAAGCGGATGGAATCGGTCGCCGGCGCCTGGGTGGAGCAGAAGGCGATCCGGGACATCATGGTGTTCCTG
CAGTCCAATGGCCTTGGAACCGCCCGCGCCGTGAGGATCTACAAGAGCTACGGCAACGAAGCGATCTTCAAGGTGACCGA
AAACCCGTACCGGCTGGCCCTGGAGATCCATGGCATAGGTTTCAAGACTGCCGACCTCCTGGCTGCCAAGCTGGGGATAG
CGCCCGATTCCATGATCCGGGCCCAGGCGGGGGTGCGGCACGTGCTGCAGGAGATGTCGGCCGGCGGGCACTGCGCCAGC
CTGCGGGCGGAACTGGCCGAGAGCGCAGCTACTCTGCTGGAGATCCCTCAACCGGTAATCGAATCCGCCATCGAGGCGGA
ACTCGCCGAGGAGAACCTGGTCGCCGACCAGATCTCCGGCTCCCCCTGCGTCTTCCTGGCGCCGCTCTACAAGGCGGAGG
TAGGCGTAGCCTCCGGCATTTGCCGGCTTCGCGCCGGCACGCCCCCTTGGGGCGGCATCGTCGCCGAAGAGGCGATCCCG
TGGGTGGAGAGCCAAAAAGGAATCACCCTTTCCGCCTCGCAGCGCGATGCGATTCGGCTCGCGCTTAAGAGCAAGGTGGT
CGTGGTGACCGGCGGACCGGGGGTGGGTAAGACCACGCTGGTCAACAGCATCCTGGGTGTCATCGGCAGAAGGCCGCTCC
GGGTCACCCTCTGCGCGCCGACGGGGAGGGCAGCCAAGCGCCTCGCCGAATCGACCGGGATGGAGGCGAAGACCATCCAT
CGGCTCTTGGAGTTCGACCCGCAGACCTTCGGCTTCAAGCGCTGCAAGGAGAACCCGCTTCACACCGACCTCCTGGTCAT
GGACGAGGCGTCCATGGTCGACGTCGTGTTGATGAACAAGCTCCTTCCCGCCATTCCCGACCATGCCGGCCTCATCATCG
TGGGGGACGTGGACCAGCTCCCCTCGGTGGGGCCAGGCTGCGTCCTCTCCGACATCATCGAGTCCGGCGCGGTTCCGACG
GTACGGCTCACCGAGATCTTCCGGCAGGCCGCAGGCTCCAGGATCATCGTCAACGCCCACCGCATCAACCGGGGTGAGCT
GCCGCTGAAGGACGAGGGGAAGGAGCTCGCCGACTTCTACTTCATCCCGGCGGCGACGCCCGAGGATATCCACGACAAGC
TCCTGCAGGTGGTCAGGGAGCGGATACCCAAGCGCTTCGGCTTCGATCCGGTGCGCGAGGTCCAGGTGCTTACGCCGATG
AACCGCGGGGGGCTCGGGACCAGGTCCCTCAACGCCGAGTTGCAGGGGGTGCTGAACGGCAGGGCCGAGCCGAAGGTGGA
GCGCTTCGGCACCAGCTACGCCCCCGGGGACAAGGTGATCCAGACGGTGAACAACTACGAGAAGGAGGTCTTCAACGGGG
ACATCGGACGCATAGTCGAGATCCGCTCCGAAGAAAGCGCCCTCATCGTGGACTTCGATGACCGGCTGGTGGAATATGCA
TTCGCCGAACTGGACGAGGTGAGCCTTGCCTACGCCACCAGCATCCACAAGAGCCAGGGGTCCGAGTACACGGCCGTGGT
GATCCCGCTTGCCATGCAGCACTACACCATGCTGGAGCGAAACCTCCTGTACACCGCCGTCACCCGCGGCAAGAAGCTCG
TGGTGGTGATCGGCGAGCAGAAGGCGCTCGCCATGGCGGTGCAAAACCAGAAGTCCCACCGCCGCCTGACCAAGCTGGCG
GGGAGGATCGGACAGAAAGGAGACGGGATAACATGA

Upstream 100 bases:

>100_bases
GACTCTTCTTCCCTGAATTCTTCGAAGAACCTTAAAAACTGATGCGATTTCAGCTGGCTTGCCTGTGGCTATCCCGCTGC
CGAGCCCGAACGGAACTGCC

Downstream 100 bases:

>100_bases
AAACCATTGGCATGATTGGCGGCCTGGGCCCGGAAGCTACGCTTGATTACTACAAGCGCATCATCGAAGCCTCAAGGGGA
GCCGGAACCCTCGATACCCC

Product: helicase, RecD/TraA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MKETPPTENVDRLSGSLERVTFHSEETGFCVLRVKVAGQRDLVTVTGAAASVTPGEYLECTGSWHNDRTHGMQFKAGHIK
VVPPTTLEGIEKYLGSGMVHGIGAHFAKVLVKSFGAAVFDVIENHPERLLELPGIGRKRMESVAGAWVEQKAIRDIMVFL
QSNGLGTARAVRIYKSYGNEAIFKVTENPYRLALEIHGIGFKTADLLAAKLGIAPDSMIRAQAGVRHVLQEMSAGGHCAS
LRAELAESAATLLEIPQPVIESAIEAELAEENLVADQISGSPCVFLAPLYKAEVGVASGICRLRAGTPPWGGIVAEEAIP
WVESQKGITLSASQRDAIRLALKSKVVVVTGGPGVGKTTLVNSILGVIGRRPLRVTLCAPTGRAAKRLAESTGMEAKTIH
RLLEFDPQTFGFKRCKENPLHTDLLVMDEASMVDVVLMNKLLPAIPDHAGLIIVGDVDQLPSVGPGCVLSDIIESGAVPT
VRLTEIFRQAAGSRIIVNAHRINRGELPLKDEGKELADFYFIPAATPEDIHDKLLQVVRERIPKRFGFDPVREVQVLTPM
NRGGLGTRSLNAELQGVLNGRAEPKVERFGTSYAPGDKVIQTVNNYEKEVFNGDIGRIVEIRSEESALIVDFDDRLVEYA
FAELDEVSLAYATSIHKSQGSEYTAVVIPLAMQHYTMLERNLLYTAVTRGKKLVVVIGEQKALAMAVQNQKSHRRLTKLA
GRIGQKGDGIT

Sequences:

>Translated_731_residues
MKETPPTENVDRLSGSLERVTFHSEETGFCVLRVKVAGQRDLVTVTGAAASVTPGEYLECTGSWHNDRTHGMQFKAGHIK
VVPPTTLEGIEKYLGSGMVHGIGAHFAKVLVKSFGAAVFDVIENHPERLLELPGIGRKRMESVAGAWVEQKAIRDIMVFL
QSNGLGTARAVRIYKSYGNEAIFKVTENPYRLALEIHGIGFKTADLLAAKLGIAPDSMIRAQAGVRHVLQEMSAGGHCAS
LRAELAESAATLLEIPQPVIESAIEAELAEENLVADQISGSPCVFLAPLYKAEVGVASGICRLRAGTPPWGGIVAEEAIP
WVESQKGITLSASQRDAIRLALKSKVVVVTGGPGVGKTTLVNSILGVIGRRPLRVTLCAPTGRAAKRLAESTGMEAKTIH
RLLEFDPQTFGFKRCKENPLHTDLLVMDEASMVDVVLMNKLLPAIPDHAGLIIVGDVDQLPSVGPGCVLSDIIESGAVPT
VRLTEIFRQAAGSRIIVNAHRINRGELPLKDEGKELADFYFIPAATPEDIHDKLLQVVRERIPKRFGFDPVREVQVLTPM
NRGGLGTRSLNAELQGVLNGRAEPKVERFGTSYAPGDKVIQTVNNYEKEVFNGDIGRIVEIRSEESALIVDFDDRLVEYA
FAELDEVSLAYATSIHKSQGSEYTAVVIPLAMQHYTMLERNLLYTAVTRGKKLVVVIGEQKALAMAVQNQKSHRRLTKLA
GRIGQKGDGIT
>Mature_731_residues
MKETPPTENVDRLSGSLERVTFHSEETGFCVLRVKVAGQRDLVTVTGAAASVTPGEYLECTGSWHNDRTHGMQFKAGHIK
VVPPTTLEGIEKYLGSGMVHGIGAHFAKVLVKSFGAAVFDVIENHPERLLELPGIGRKRMESVAGAWVEQKAIRDIMVFL
QSNGLGTARAVRIYKSYGNEAIFKVTENPYRLALEIHGIGFKTADLLAAKLGIAPDSMIRAQAGVRHVLQEMSAGGHCAS
LRAELAESAATLLEIPQPVIESAIEAELAEENLVADQISGSPCVFLAPLYKAEVGVASGICRLRAGTPPWGGIVAEEAIP
WVESQKGITLSASQRDAIRLALKSKVVVVTGGPGVGKTTLVNSILGVIGRRPLRVTLCAPTGRAAKRLAESTGMEAKTIH
RLLEFDPQTFGFKRCKENPLHTDLLVMDEASMVDVVLMNKLLPAIPDHAGLIIVGDVDQLPSVGPGCVLSDIIESGAVPT
VRLTEIFRQAAGSRIIVNAHRINRGELPLKDEGKELADFYFIPAATPEDIHDKLLQVVRERIPKRFGFDPVREVQVLTPM
NRGGLGTRSLNAELQGVLNGRAEPKVERFGTSYAPGDKVIQTVNNYEKEVFNGDIGRIVEIRSEESALIVDFDDRLVEYA
FAELDEVSLAYATSIHKSQGSEYTAVVIPLAMQHYTMLERNLLYTAVTRGKKLVVVIGEQKALAMAVQNQKSHRRLTKLA
GRIGQKGDGIT

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32455236, Length=265, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1789182, Length=450, Percent_Identity=29.7777777777778, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 79258; Mature: 79258

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETPPTENVDRLSGSLERVTFHSEETGFCVLRVKVAGQRDLVTVTGAAASVTPGEYLEC
CCCCCCCCCHHHHCCCHHEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCEEE
TGSWHNDRTHGMQFKAGHIKVVPPTTLEGIEKYLGSGMVHGIGAHFAKVLVKSFGAAVFD
CCCCCCCCCCCEEEECCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VIENHPERLLELPGIGRKRMESVAGAWVEQKAIRDIMVFLQSNGLGTARAVRIYKSYGNE
HHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
AIFKVTENPYRLALEIHGIGFKTADLLAAKLGIAPDSMIRAQAGVRHVLQEMSAGGHCAS
EEEEEECCCEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
LRAELAESAATLLEIPQPVIESAIEAELAEENLVADQISGSPCVFLAPLYKAEVGVASGI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCH
CRLRAGTPPWGGIVAEEAIPWVESQKGITLSASQRDAIRLALKSKVVVVTGGPGVGKTTL
HEECCCCCCCCCEEHHHCCCCCCCCCCEEEECCCCHHHEEEEECEEEEEECCCCCCHHHH
VNSILGVIGRRPLRVTLCAPTGRAAKRLAESTGMEAKTIHRLLEFDPQTFGFKRCKENPL
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHCCCCC
HTDLLVMDEASMVDVVLMNKLLPAIPDHAGLIIVGDVDQLPSVGPGCVLSDIIESGAVPT
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCCCCHHHHHHHHCCCCCC
VRLTEIFRQAAGSRIIVNAHRINRGELPLKDEGKELADFYFIPAATPEDIHDKLLQVVRE
HHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
RIPKRFGFDPVREVQVLTPMNRGGLGTRSLNAELQGVLNGRAEPKVERFGTSYAPGDKVI
HHHHHCCCCHHHHEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCCCHHHHH
QTVNNYEKEVFNGDIGRIVEIRSEESALIVDFDDRLVEYAFAELDEVSLAYATSIHKSQG
HHHHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEYTAVVIPLAMQHYTMLERNLLYTAVTRGKKLVVVIGEQKALAMAVQNQKSHRRLTKLA
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHH
GRIGQKGDGIT
HHCCCCCCCCC
>Mature Secondary Structure
MKETPPTENVDRLSGSLERVTFHSEETGFCVLRVKVAGQRDLVTVTGAAASVTPGEYLEC
CCCCCCCCCHHHHCCCHHEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCEEE
TGSWHNDRTHGMQFKAGHIKVVPPTTLEGIEKYLGSGMVHGIGAHFAKVLVKSFGAAVFD
CCCCCCCCCCCEEEECCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VIENHPERLLELPGIGRKRMESVAGAWVEQKAIRDIMVFLQSNGLGTARAVRIYKSYGNE
HHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
AIFKVTENPYRLALEIHGIGFKTADLLAAKLGIAPDSMIRAQAGVRHVLQEMSAGGHCAS
EEEEEECCCEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
LRAELAESAATLLEIPQPVIESAIEAELAEENLVADQISGSPCVFLAPLYKAEVGVASGI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCH
CRLRAGTPPWGGIVAEEAIPWVESQKGITLSASQRDAIRLALKSKVVVVTGGPGVGKTTL
HEECCCCCCCCCEEHHHCCCCCCCCCCEEEECCCCHHHEEEEECEEEEEECCCCCCHHHH
VNSILGVIGRRPLRVTLCAPTGRAAKRLAESTGMEAKTIHRLLEFDPQTFGFKRCKENPL
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHCCCCC
HTDLLVMDEASMVDVVLMNKLLPAIPDHAGLIIVGDVDQLPSVGPGCVLSDIIESGAVPT
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCCCCHHHHHHHHCCCCCC
VRLTEIFRQAAGSRIIVNAHRINRGELPLKDEGKELADFYFIPAATPEDIHDKLLQVVRE
HHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
RIPKRFGFDPVREVQVLTPMNRGGLGTRSLNAELQGVLNGRAEPKVERFGTSYAPGDKVI
HHHHHCCCCHHHHEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCCCHHHHH
QTVNNYEKEVFNGDIGRIVEIRSEESALIVDFDDRLVEYAFAELDEVSLAYATSIHKSQG
HHHHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEYTAVVIPLAMQHYTMLERNLLYTAVTRGKKLVVVIGEQKALAMAVQNQKSHRRLTKLA
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHH
GRIGQKGDGIT
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]