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The map label for this gene is kup [H]

Identifier: 197117561

GI number: 197117561

Start: 1364790

End: 1366610

Strand: Direct

Name: kup [H]

Synonym: Gbem_1173

Alternate gene names: 197117561

Gene position: 1364790-1366610 (Clockwise)

Preceding gene: 197117560

Following gene: 197117564

Centisome position: 29.57

GC content: 61.89

Gene sequence:

>1821_bases
ATGAATAACGAAGCGCCCCAATCCTACTGGAGCGGCATCGTCAAGGCGATGGGGCTCGTCTTCGGGGACATCGGCACCAG
CCCGATCTACACCCTCACCGTCATCTTCGCCCTCACCCCCGCAACGCCCGGGAACGTCTTCGGGATCCTTTCGCTCGTCT
TTTGGACCATGACCCTCCTGGTCAGCGCCGAGTACGCCTGGCTCGCCATGAGCCTCAGCCGCAAGGGGGAGGGGGGGACC
ATCGTTCTCAAGGAGATCCTGGTCCGGATGCTGAAGCCGGGGCGGCAGCTCGCCTTCGTGGTTTTCCTCTCTTACCTGGG
AGCCTGCCTGCTGTTGGGCGACGGGGTGATCACCCCGGCCATCTCCATCCTCTCCGCGGTGGAAGGGCTCGAGCTGATAC
CCGGCCTGGAGCATACCGGCCAGGGTGAGCTGATCCTGATCGCCGCGGTGATCGCGGTGGGGCTTTTCCTGGCGCAGTCG
AAGGGGACCGACAAGGTAGCGGGGGCCTTCGGCCCCATCATGGTGGTATGGTTCGGGGCGCTTGCCTTTTCCGGCCTCGC
CTCCATCAGCTCCATGCCCTCCATCTTGAGCGCCATCAACCCTTACTACGCGCTGGATTTCATGCTGCATCACGGCCTGG
GAGGGTTCTTCGTGCTCTCCGAGGTGATACTCTGCGCCACCGGCGGCGAGGCGCTCTACGCCGACATGGGGCACCTGGGG
CGCAGGCCGATCCTGCGCGCCTGGTACTTCGCCTTCACCGCGCTGGTGATCAACTACCTGGGCCAGGGAGTCTTCCTGCT
CAGTCACCCGGAGGCGAAGAACTACCTCTTCGGGATGGTGCAGAACCAGGCCCCGTTTCTCTACATCCCGTTCCTGATCC
TCACCGTGCTCGCCACCGTCATCGCCTCGCAGGCGATGATCAGCGGCGTTTTCTCCGTGGTCTACCAGGGGATCACCACC
CGCATACTTCCCCTCTTGCGGGTGGAGTTCACCTCGACGCACCTGAAGTCGCAGATCTACCTCTCCTCGGTCAACTGGAT
CCTGATGCTGGCCGTCCTCGTGGTGATGCTGTACTTCAAAAGGAGCGAGCACCTGGCCGCGGCGTACGGGCTGGCGGTCA
CCGGGACCATGACCATCACCGGGATCATGATGGTGATGATCTTCTCCCGCACCACCAAGAAGTGGAAGGTCCCCCTGGCC
GTCGCTGTGACCGTGGTGGACCTCATCTTCTTCCTCTCCTGCCTGAACAAGATCCCCCACGGCGGCTACTGGTCCATCGT
GTTAGGCTCGATCCCTTTCTGCATCATCATGGTCTGGACCCGGGGGCAGCGCGCCCTGTACCGTGCGCTCAAGCCGCTGG
ACCTCGACACCTTCGACGTCGCCTACCGCCAGATCTACGCGAAAGAAAAGAACATCCCCGGTACCTCCCTTTTCTTCGTC
AAGGAATGGAGCGTTATTCCCCCTTATCTGGTGCACTGCATCATCCGCAGCAACATCATCTACGAGCGCAACGTCCTGAT
CTCGATCCTGCGCACGGACGAGCCGTACGGCCTGAAGGTCGACTTGAAGCGCGACCTCTCCGTAGGGCTCGACGCCATCG
AGATCAAGGCCGGCTACCTGGAGATTCTGGATATCGAGGCGGTCTTGAAGGAAAACGGGATTCAGGAGAAGGTGATCTTC
TACGGGGTCGAGGACATCGTCACCGACAACCCGGTCTGGAAGCTCTTCGCCACCATCAAGCGGCAGACTCCCAACTTCGT
GCAGTTCCACAACCTTCCCCCCGCGAAGCTCCAGGGGGTCGTGACCCGGGTGGAGATGTGA

Upstream 100 bases:

>100_bases
CCATCAGCAACCTGAGGAAGAAGGTCGAGCGGGACCCCTCGCGCCCCAGGCACATCACCACCGAACCCGGGGTCGGGTAT
CGGTTCAAGCAGGTGCAACC

Downstream 100 bases:

>100_bases
ATGAAAAAGGGGGCCGGCTTCCAACCGGCCCCCTTCCTTTGCCCCATGGCTCGTTCCTGCCTCGCTTTCTAGCGCTCTTC
GCCTATCGCCCCCTGCATCT

Product: Kup system potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MNNEAPQSYWSGIVKAMGLVFGDIGTSPIYTLTVIFALTPATPGNVFGILSLVFWTMTLLVSAEYAWLAMSLSRKGEGGT
IVLKEILVRMLKPGRQLAFVVFLSYLGACLLLGDGVITPAISILSAVEGLELIPGLEHTGQGELILIAAVIAVGLFLAQS
KGTDKVAGAFGPIMVVWFGALAFSGLASISSMPSILSAINPYYALDFMLHHGLGGFFVLSEVILCATGGEALYADMGHLG
RRPILRAWYFAFTALVINYLGQGVFLLSHPEAKNYLFGMVQNQAPFLYIPFLILTVLATVIASQAMISGVFSVVYQGITT
RILPLLRVEFTSTHLKSQIYLSSVNWILMLAVLVVMLYFKRSEHLAAAYGLAVTGTMTITGIMMVMIFSRTTKKWKVPLA
VAVTVVDLIFFLSCLNKIPHGGYWSIVLGSIPFCIIMVWTRGQRALYRALKPLDLDTFDVAYRQIYAKEKNIPGTSLFFV
KEWSVIPPYLVHCIIRSNIIYERNVLISILRTDEPYGLKVDLKRDLSVGLDAIEIKAGYLEILDIEAVLKENGIQEKVIF
YGVEDIVTDNPVWKLFATIKRQTPNFVQFHNLPPAKLQGVVTRVEM

Sequences:

>Translated_606_residues
MNNEAPQSYWSGIVKAMGLVFGDIGTSPIYTLTVIFALTPATPGNVFGILSLVFWTMTLLVSAEYAWLAMSLSRKGEGGT
IVLKEILVRMLKPGRQLAFVVFLSYLGACLLLGDGVITPAISILSAVEGLELIPGLEHTGQGELILIAAVIAVGLFLAQS
KGTDKVAGAFGPIMVVWFGALAFSGLASISSMPSILSAINPYYALDFMLHHGLGGFFVLSEVILCATGGEALYADMGHLG
RRPILRAWYFAFTALVINYLGQGVFLLSHPEAKNYLFGMVQNQAPFLYIPFLILTVLATVIASQAMISGVFSVVYQGITT
RILPLLRVEFTSTHLKSQIYLSSVNWILMLAVLVVMLYFKRSEHLAAAYGLAVTGTMTITGIMMVMIFSRTTKKWKVPLA
VAVTVVDLIFFLSCLNKIPHGGYWSIVLGSIPFCIIMVWTRGQRALYRALKPLDLDTFDVAYRQIYAKEKNIPGTSLFFV
KEWSVIPPYLVHCIIRSNIIYERNVLISILRTDEPYGLKVDLKRDLSVGLDAIEIKAGYLEILDIEAVLKENGIQEKVIF
YGVEDIVTDNPVWKLFATIKRQTPNFVQFHNLPPAKLQGVVTRVEM
>Mature_606_residues
MNNEAPQSYWSGIVKAMGLVFGDIGTSPIYTLTVIFALTPATPGNVFGILSLVFWTMTLLVSAEYAWLAMSLSRKGEGGT
IVLKEILVRMLKPGRQLAFVVFLSYLGACLLLGDGVITPAISILSAVEGLELIPGLEHTGQGELILIAAVIAVGLFLAQS
KGTDKVAGAFGPIMVVWFGALAFSGLASISSMPSILSAINPYYALDFMLHHGLGGFFVLSEVILCATGGEALYADMGHLG
RRPILRAWYFAFTALVINYLGQGVFLLSHPEAKNYLFGMVQNQAPFLYIPFLILTVLATVIASQAMISGVFSVVYQGITT
RILPLLRVEFTSTHLKSQIYLSSVNWILMLAVLVVMLYFKRSEHLAAAYGLAVTGTMTITGIMMVMIFSRTTKKWKVPLA
VAVTVVDLIFFLSCLNKIPHGGYWSIVLGSIPFCIIMVWTRGQRALYRALKPLDLDTFDVAYRQIYAKEKNIPGTSLFFV
KEWSVIPPYLVHCIIRSNIIYERNVLISILRTDEPYGLKVDLKRDLSVGLDAIEIKAGYLEILDIEAVLKENGIQEKVIF
YGVEDIVTDNPVWKLFATIKRQTPNFVQFHNLPPAKLQGVVTRVEM

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=635, Percent_Identity=34.1732283464567, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 66764; Mature: 66764

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEAPQSYWSGIVKAMGLVFGDIGTSPIYTLTVIFALTPATPGNVFGILSLVFWTMTLL
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VSAEYAWLAMSLSRKGEGGTIVLKEILVRMLKPGRQLAFVVFLSYLGACLLLGDGVITPA
HHCCHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
ISILSAVEGLELIPGLEHTGQGELILIAAVIAVGLFLAQSKGTDKVAGAFGPIMVVWFGA
HHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LAFSGLASISSMPSILSAINPYYALDFMLHHGLGGFFVLSEVILCATGGEALYADMGHLG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
RRPILRAWYFAFTALVINYLGQGVFLLSHPEAKNYLFGMVQNQAPFLYIPFLILTVLATV
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHEECCCCCEEHHHHHHHHHHHHH
IASQAMISGVFSVVYQGITTRILPLLRVEFTSTHLKSQIYLSSVNWILMLAVLVVMLYFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSEHLAAAYGLAVTGTMTITGIMMVMIFSRTTKKWKVPLAVAVTVVDLIFFLSCLNKIPH
CCCHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GGYWSIVLGSIPFCIIMVWTRGQRALYRALKPLDLDTFDVAYRQIYAKEKNIPGTSLFFV
CCCHHHHHHCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
KEWSVIPPYLVHCIIRSNIIYERNVLISILRTDEPYGLKVDLKRDLSVGLDAIEIKAGYL
ECCCCCHHHHHHHHHHCCCEEECCCEEEEEECCCCCCEEEEECCCHHCCCCEEEEECCCE
EILDIEAVLKENGIQEKVIFYGVEDIVTDNPVWKLFATIKRQTPNFVQFHNLPPAKLQGV
EEEHHHHHHHHCCCCCHHEEEEHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHH
VTRVEM
HHHCCC
>Mature Secondary Structure
MNNEAPQSYWSGIVKAMGLVFGDIGTSPIYTLTVIFALTPATPGNVFGILSLVFWTMTLL
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VSAEYAWLAMSLSRKGEGGTIVLKEILVRMLKPGRQLAFVVFLSYLGACLLLGDGVITPA
HHCCHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
ISILSAVEGLELIPGLEHTGQGELILIAAVIAVGLFLAQSKGTDKVAGAFGPIMVVWFGA
HHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LAFSGLASISSMPSILSAINPYYALDFMLHHGLGGFFVLSEVILCATGGEALYADMGHLG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
RRPILRAWYFAFTALVINYLGQGVFLLSHPEAKNYLFGMVQNQAPFLYIPFLILTVLATV
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHEECCCCCEEHHHHHHHHHHHHH
IASQAMISGVFSVVYQGITTRILPLLRVEFTSTHLKSQIYLSSVNWILMLAVLVVMLYFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSEHLAAAYGLAVTGTMTITGIMMVMIFSRTTKKWKVPLAVAVTVVDLIFFLSCLNKIPH
CCCHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GGYWSIVLGSIPFCIIMVWTRGQRALYRALKPLDLDTFDVAYRQIYAKEKNIPGTSLFFV
CCCHHHHHHCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
KEWSVIPPYLVHCIIRSNIIYERNVLISILRTDEPYGLKVDLKRDLSVGLDAIEIKAGYL
ECCCCCHHHHHHHHHHCCCEEECCCEEEEEECCCCCCEEEEECCCHHCCCCEEEEECCCE
EILDIEAVLKENGIQEKVIFYGVEDIVTDNPVWKLFATIKRQTPNFVQFHNLPPAKLQGV
EEEHHHHHHHHCCCCCHHEEEEHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHH
VTRVEM
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA