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The map label for this gene is nlpI [C]

Identifier: 197117495

GI number: 197117495

Start: 1277565

End: 1279382

Strand: Reverse

Name: nlpI [C]

Synonym: Gbem_1106

Alternate gene names: 197117495

Gene position: 1279382-1277565 (Counterclockwise)

Preceding gene: 197117499

Following gene: 197117493

Centisome position: 27.72

GC content: 60.67

Gene sequence:

>1818_bases
ATGACGTACACGCGCTCTACCCAAAAGCACCTCCTGGTGTTTCTGATTTTGGCCCTCGTGGGCCTCGCGGCCTACGGCAA
TACCTTCTCCGTCCCGTTCCAGTTCGACGACGACGCCTACATCGTTAACAACCCCGCCATCAAGGATTTCAACGCCTTCA
TATCACCGGGCACCGTCACTGGAGGAGCAGAGCTCTCACCGACCGCCATCCCGCCTGCACTGCGGGTCGCTTTCATGACG
CGCATCGTGGGTTACCTTTCGCTCGCAGTCGACTACCACATACACGGCCTGCAGGTCGCCGGGTACCATATCGTCAATCT
TGCACTGCATATCATTAACGCATGGCTCGTGTACCTGGTGCTGGGGCACCTGTTCGGGGTCAGGGGGAAGGACGAGCTCG
AAGAAGGGTCCGCCGGGATAAGGCCACTGCCACTGATCGGGGCACTACTGTTTCTTTGCCATCCGATCCAAACCCACGCG
GTCACCTACGTCACGTCGCGCTTCGTCCTCCTGGCCTCATTCTTCTCATTGCTCGCCTTGACCTCCTACCTCGGCTTTCG
CGAGGCCCACAATGGCTCCCGAGCGAAGTTCTACCTCGCCCTTTGCGTCGTCTCCGCCTCGCTGGGCATGCTGACCAAGG
AATTCACCTTCACCCTCCCCTTCGTCATCGCGCTTTACGAGTTCTCCTTCTTCCCCGGCACCTTTCGCGACCATCTGCGG
AAGGTCTGGCCGGTTGCGCTTGCCGTTCCCATCATCCCCGGTCTCATCTTCCTCCAGAAAGGGCAACTCACCGCCCTCGG
CGGCACCATGCGCACCCTCACCGCCGCGGACTCGTCCGGCATCGGAAGGCTCGACTACCTGCTGACCCAGTTCAACGTGG
TGGCAGGCTACCTGCGCTTGCTGCTCTTCCCTTTGGGGCAGAACGTCGACCACGACTTCGCGGTGCAGCACAACCTTGCC
GCTCCAGCCGTCCTCCTCCCGCTTTTGCTGCTGCTATGCCTGTTCGGCTGGGCTGCCGTCGGGTACGTCCGTTCCCTGCG
CGCCGGGGACGCCGCAGCGAGGGTGATCCCTTTCGGCATCCTCTGGTTTTTCATGACCTTATCGGTCGAGTCAAGCATCA
TCCCTCTCGGAGAGTTGTCCGCGGAGTACCGGCTTTACCTCCCCTCCCTTGGGGTAATCATCGTGCTGTGTTGGCTCGCT
GACCGGGCATGCCTGCGTCTGTCGGCGGGAAGAAGGGCTCGGTTCGCGGCTGCCCTTGTCGTCATCGGGATGCTCGGTAC
GCTGACCATCCTGCGCAACAGCGTGTGGCAAAGCGAAATTTCATTGTGGCGGGACGCGGTGAAAAAGAGTCCGGCGAAGC
TGAGGCCCCATCAAAACCTGGCGCTCTATTACGGGAAGGCAGGACGGTTGGAAGAAGCGAGACAGGAACTGCAGCAGGCG
ATCGCCATCAAACCGGACGACTTCGAACTGCACAACAACCTGGGCATCGTCTATCGGCAACAGGGGAACCTCGATGCCGC
GATCCTGGAGTACGAGCGCGCCCTGCAGCTCGAACCCGCCGATGCGATGGCGCGCTACAACCTTGGCAACGCCTACCTGG
GACGGGGAAGGTACCAGGAGGCGCTTGAACAGTACCAGTCATGCCTCAAACTGATCCCGGATTACGACGATCTCCACAAC
AACATGGGCATCGTCTACAACAAAGCCGGACAAAGCGACGCCGCGATCAAGGAGTTCCAGGAGGCCCTGCGCCTCAATCC
GGCAAACGCACATGCCAGGAGGAACCTGGAAAGCAGCATGAACCGGGCGACGAGGTGA

Upstream 100 bases:

>100_bases
ACAATTCAAACTTTATATGATACATTGGGCGCCCTGTCGGCCCTTGGCTGATTTCGTCTCAGCTAACAACCACTTCCTCA
CGACAAAGGTACCTACCAGC

Downstream 100 bases:

>100_bases
AGCGGGCCTGGCCGCTTGGGGAGATACCCCATTGAGCGGCCGGCTGCACATCGTTGTCCTTGCCGTCCGCGTTACCGGAA
AATCCCGCTCTTCACGAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MTYTRSTQKHLLVFLILALVGLAAYGNTFSVPFQFDDDAYIVNNPAIKDFNAFISPGTVTGGAELSPTAIPPALRVAFMT
RIVGYLSLAVDYHIHGLQVAGYHIVNLALHIINAWLVYLVLGHLFGVRGKDELEEGSAGIRPLPLIGALLFLCHPIQTHA
VTYVTSRFVLLASFFSLLALTSYLGFREAHNGSRAKFYLALCVVSASLGMLTKEFTFTLPFVIALYEFSFFPGTFRDHLR
KVWPVALAVPIIPGLIFLQKGQLTALGGTMRTLTAADSSGIGRLDYLLTQFNVVAGYLRLLLFPLGQNVDHDFAVQHNLA
APAVLLPLLLLLCLFGWAAVGYVRSLRAGDAAARVIPFGILWFFMTLSVESSIIPLGELSAEYRLYLPSLGVIIVLCWLA
DRACLRLSAGRRARFAAALVVIGMLGTLTILRNSVWQSEISLWRDAVKKSPAKLRPHQNLALYYGKAGRLEEARQELQQA
IAIKPDDFELHNNLGIVYRQQGNLDAAILEYERALQLEPADAMARYNLGNAYLGRGRYQEALEQYQSCLKLIPDYDDLHN
NMGIVYNKAGQSDAAIKEFQEALRLNPANAHARRNLESSMNRATR

Sequences:

>Translated_605_residues
MTYTRSTQKHLLVFLILALVGLAAYGNTFSVPFQFDDDAYIVNNPAIKDFNAFISPGTVTGGAELSPTAIPPALRVAFMT
RIVGYLSLAVDYHIHGLQVAGYHIVNLALHIINAWLVYLVLGHLFGVRGKDELEEGSAGIRPLPLIGALLFLCHPIQTHA
VTYVTSRFVLLASFFSLLALTSYLGFREAHNGSRAKFYLALCVVSASLGMLTKEFTFTLPFVIALYEFSFFPGTFRDHLR
KVWPVALAVPIIPGLIFLQKGQLTALGGTMRTLTAADSSGIGRLDYLLTQFNVVAGYLRLLLFPLGQNVDHDFAVQHNLA
APAVLLPLLLLLCLFGWAAVGYVRSLRAGDAAARVIPFGILWFFMTLSVESSIIPLGELSAEYRLYLPSLGVIIVLCWLA
DRACLRLSAGRRARFAAALVVIGMLGTLTILRNSVWQSEISLWRDAVKKSPAKLRPHQNLALYYGKAGRLEEARQELQQA
IAIKPDDFELHNNLGIVYRQQGNLDAAILEYERALQLEPADAMARYNLGNAYLGRGRYQEALEQYQSCLKLIPDYDDLHN
NMGIVYNKAGQSDAAIKEFQEALRLNPANAHARRNLESSMNRATR
>Mature_604_residues
TYTRSTQKHLLVFLILALVGLAAYGNTFSVPFQFDDDAYIVNNPAIKDFNAFISPGTVTGGAELSPTAIPPALRVAFMTR
IVGYLSLAVDYHIHGLQVAGYHIVNLALHIINAWLVYLVLGHLFGVRGKDELEEGSAGIRPLPLIGALLFLCHPIQTHAV
TYVTSRFVLLASFFSLLALTSYLGFREAHNGSRAKFYLALCVVSASLGMLTKEFTFTLPFVIALYEFSFFPGTFRDHLRK
VWPVALAVPIIPGLIFLQKGQLTALGGTMRTLTAADSSGIGRLDYLLTQFNVVAGYLRLLLFPLGQNVDHDFAVQHNLAA
PAVLLPLLLLLCLFGWAAVGYVRSLRAGDAAARVIPFGILWFFMTLSVESSIIPLGELSAEYRLYLPSLGVIIVLCWLAD
RACLRLSAGRRARFAAALVVIGMLGTLTILRNSVWQSEISLWRDAVKKSPAKLRPHQNLALYYGKAGRLEEARQELQQAI
AIKPDDFELHNNLGIVYRQQGNLDAAILEYERALQLEPADAMARYNLGNAYLGRGRYQEALEQYQSCLKLIPDYDDLHNN
MGIVYNKAGQSDAAIKEFQEALRLNPANAHARRNLESSMNRATR

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI118766328, Length=641, Percent_Identity=25.4290171606864, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI118766330, Length=641, Percent_Identity=25.4290171606864, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI301336134, Length=661, Percent_Identity=25.1134644478064, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI83415184, Length=574, Percent_Identity=26.4808362369338, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI32307150, Length=159, Percent_Identity=30.8176100628931, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI32307148, Length=159, Percent_Identity=30.8176100628931, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI22749211, Length=237, Percent_Identity=27.0042194092827, Blast_Score=74, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147174, Length=583, Percent_Identity=23.6706689536878, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI115532692, Length=167, Percent_Identity=32.9341317365269, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI115532690, Length=167, Percent_Identity=32.9341317365269, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319387, Length=155, Percent_Identity=28.3870967741935, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19920486, Length=226, Percent_Identity=30.0884955752212, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI161076610, Length=226, Percent_Identity=30.0884955752212, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647123, Length=239, Percent_Identity=30.9623430962343, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24581187, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364285, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647755, Length=138, Percent_Identity=31.8840579710145, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24585827, Length=138, Percent_Identity=31.8840579710145, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24585829, Length=138, Percent_Identity=31.8840579710145, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24656717, Length=306, Percent_Identity=22.5490196078431, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI18110006, Length=306, Percent_Identity=22.5490196078431, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000863
- InterPro:   IPR001440
- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00685 Sulfotransfer_1; PF00515 TPR_1; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 66915; Mature: 66784

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTRSTQKHLLVFLILALVGLAAYGNTFSVPFQFDDDAYIVNNPAIKDFNAFISPGTVT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCHHHHHHCCCCCCC
GGAELSPTAIPPALRVAFMTRIVGYLSLAVDYHIHGLQVAGYHIVNLALHIINAWLVYLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECEEEEHHHHHHHHHHHHHHHHHHHHH
LGHLFGVRGKDELEEGSAGIRPLPLIGALLFLCHPIQTHAVTYVTSRFVLLASFFSLLAL
HHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TSYLGFREAHNGSRAKFYLALCVVSASLGMLTKEFTFTLPFVIALYEFSFFPGTFRDHLR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KVWPVALAVPIIPGLIFLQKGQLTALGGTMRTLTAADSSGIGRLDYLLTQFNVVAGYLRL
HHHHHHHHHHHHHHHHEEECCCEEECCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHH
LLFPLGQNVDHDFAVQHNLAAPAVLLPLLLLLCLFGWAAVGYVRSLRAGDAAARVIPFGI
HHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LWFFMTLSVESSIIPLGELSAEYRLYLPSLGVIIVLCWLADRACLRLSAGRRARFAAALV
HHHHHHHHHCCCCCCHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIGMLGTLTILRNSVWQSEISLWRDAVKKSPAKLRPHQNLALYYGKAGRLEEARQELQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
IAIKPDDFELHNNLGIVYRQQGNLDAAILEYERALQLEPADAMARYNLGNAYLGRGRYQE
HCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHCCCHHHH
ALEQYQSCLKLIPDYDDLHNNMGIVYNKAGQSDAAIKEFQEALRLNPANAHARRNLESSM
HHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NRATR
HHCCC
>Mature Secondary Structure 
TYTRSTQKHLLVFLILALVGLAAYGNTFSVPFQFDDDAYIVNNPAIKDFNAFISPGTVT
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCHHHHHHCCCCCCC
GGAELSPTAIPPALRVAFMTRIVGYLSLAVDYHIHGLQVAGYHIVNLALHIINAWLVYLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECEEEEHHHHHHHHHHHHHHHHHHHHH
LGHLFGVRGKDELEEGSAGIRPLPLIGALLFLCHPIQTHAVTYVTSRFVLLASFFSLLAL
HHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TSYLGFREAHNGSRAKFYLALCVVSASLGMLTKEFTFTLPFVIALYEFSFFPGTFRDHLR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KVWPVALAVPIIPGLIFLQKGQLTALGGTMRTLTAADSSGIGRLDYLLTQFNVVAGYLRL
HHHHHHHHHHHHHHHHEEECCCEEECCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHH
LLFPLGQNVDHDFAVQHNLAAPAVLLPLLLLLCLFGWAAVGYVRSLRAGDAAARVIPFGI
HHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LWFFMTLSVESSIIPLGELSAEYRLYLPSLGVIIVLCWLADRACLRLSAGRRARFAAALV
HHHHHHHHHCCCCCCHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIGMLGTLTILRNSVWQSEISLWRDAVKKSPAKLRPHQNLALYYGKAGRLEEARQELQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
IAIKPDDFELHNNLGIVYRQQGNLDAAILEYERALQLEPADAMARYNLGNAYLGRGRYQE
HCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHCCCHHHH
ALEQYQSCLKLIPDYDDLHNNMGIVYNKAGQSDAAIKEFQEALRLNPANAHARRNLESSM
HHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NRATR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]