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The map label for this gene is atoS [H]

Identifier: 197117408

GI number: 197117408

Start: 1185327

End: 1186652

Strand: Direct

Name: atoS [H]

Synonym: Gbem_1018

Alternate gene names: 197117408

Gene position: 1185327-1186652 (Clockwise)

Preceding gene: 197117407

Following gene: 197117410

Centisome position: 25.68

GC content: 53.32

Gene sequence:

>1326_bases
ATGAACGCCATCATCGCACAGCCAAAAGATCACGCGGCCGCCATCCTGGTTATAGACGACGACGCCAACAACCTCGCCAT
CGTTTCCTCTTTGTTGCAGGAGTACAGCTATACCATCTATGTGGCGGAGGATGGCGAGAGCGGCATCAGGCGGGCGCTTT
TAACCCGGCCCGATCTGATCCTGCTGGATGTGCTCATGCCTGGCATCGACGGTTTCGAAACCTGCCAGAGGCTCAAGGCC
GTGGAAGCGACTCGCGACATCCCGGTTATCTTCATGACTGCGCTGGCGGAGATGGACCAGAAGGTAAGGGGATTCGACGC
CGGGGCTGTGGACTACATAATCAAGCCTCTTCAGCGCGAGGAAGTCCTGGCCCGCGTGGGGGTGCATATCCACCTTCGTC
ACCTGGCAAAGGAACTGCAGGAAACCAACGCGTCGCTTGAGAAGCGGGTTGAGGACCGCACGGCGAGCCTTGCCAGCACA
AACGATGAGTTGCAGAAGGAAATCGCGGAAAGGAAGCTGGCAGAAGAGGCACTTGCCATTAAGCAGGAGCAGTTGGAGGC
ATTGAACCTGAGTCTGGAGCAACGAGTGATTGAGGAAGTGGAAAAAAATCTTCAGAAGGACCGTCTGTTGTTCCAGAATA
CGCGGTTGGCAGCGATGGGTGAGCTCTTGAACAACATTGCACATCAGTGGCGCCAGCCGCTTAACAAGATCGCGTTATTG
ATCCAGGGCTGCCTGTATGAGTCCAATGAAGGGAAACTGGAACACGAATCTTTTAAAAGCTGTGTGAATAGATGCATGGA
GCATATCACCTATCTGTCGAATACCATCAACTCATTCCAAAGCTTCTTCATGCCTGAGGGTGAGCCTGGTAAATTCGACC
CTTGTGAAACAGTGGAGAAGTCGCTGGCATTAGTCCGGAGCAGCTACGAGGAAAATGGCATCTCCGTCAGGATCATGAAC
AATGGGTCAGTGCCGATGATGGGGTTTCGCAACGCATTTTCTCAGGCTGTTTTGAGCATACTCAACAACGCCCAGCAGGT
GTTGCTGGAACGCGGCACGCCGCAACGGTTGATCGAGGTGGAGTGCCTGTACCGAGACGGCAAAAATATCGTCACGATCA
GCGACAACGGCGGCGGGATCGACGAAAAGATAATTGGAAAGATTTTCGATCCTTATTTCACCACCAAGTTCAAAGCACAA
GGGACCGGCTTAGGGCTTTACATGGCCAAAATGATCATCGAAAAGAACATGGGGGGCAGACTTTCCGCACGCAACACACA
GGCAGGAGCCGAGTTCACCATCGAACTTCCATTACCGGACAGCTGA

Upstream 100 bases:

>100_bases
GCCCGCAAAAAGGGGACAGGCACCTGCGGAGAAAGGGGGACAGGCACCTGCGGAGCCAGTCCCCGGGGATATCGGCGAAA
ACCTTTGCCGGAGAAAAGAT

Downstream 100 bases:

>100_bases
AAGCACCCGCGCGTTTAATGGCGGCAATGCTTGTGGCAAAGAAAAACCCCGCATCCGGCAAGGAGGCGGGGTTTTTAGTG
CGGGGTAGAAAAGGGCGGTT

Product: response receiver histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNAIIAQPKDHAAAILVIDDDANNLAIVSSLLQEYSYTIYVAEDGESGIRRALLTRPDLILLDVLMPGIDGFETCQRLKA
VEATRDIPVIFMTALAEMDQKVRGFDAGAVDYIIKPLQREEVLARVGVHIHLRHLAKELQETNASLEKRVEDRTASLAST
NDELQKEIAERKLAEEALAIKQEQLEALNLSLEQRVIEEVEKNLQKDRLLFQNTRLAAMGELLNNIAHQWRQPLNKIALL
IQGCLYESNEGKLEHESFKSCVNRCMEHITYLSNTINSFQSFFMPEGEPGKFDPCETVEKSLALVRSSYEENGISVRIMN
NGSVPMMGFRNAFSQAVLSILNNAQQVLLERGTPQRLIEVECLYRDGKNIVTISDNGGGIDEKIIGKIFDPYFTTKFKAQ
GTGLGLYMAKMIIEKNMGGRLSARNTQAGAEFTIELPLPDS

Sequences:

>Translated_441_residues
MNAIIAQPKDHAAAILVIDDDANNLAIVSSLLQEYSYTIYVAEDGESGIRRALLTRPDLILLDVLMPGIDGFETCQRLKA
VEATRDIPVIFMTALAEMDQKVRGFDAGAVDYIIKPLQREEVLARVGVHIHLRHLAKELQETNASLEKRVEDRTASLAST
NDELQKEIAERKLAEEALAIKQEQLEALNLSLEQRVIEEVEKNLQKDRLLFQNTRLAAMGELLNNIAHQWRQPLNKIALL
IQGCLYESNEGKLEHESFKSCVNRCMEHITYLSNTINSFQSFFMPEGEPGKFDPCETVEKSLALVRSSYEENGISVRIMN
NGSVPMMGFRNAFSQAVLSILNNAQQVLLERGTPQRLIEVECLYRDGKNIVTISDNGGGIDEKIIGKIFDPYFTTKFKAQ
GTGLGLYMAKMIIEKNMGGRLSARNTQAGAEFTIELPLPDS
>Mature_441_residues
MNAIIAQPKDHAAAILVIDDDANNLAIVSSLLQEYSYTIYVAEDGESGIRRALLTRPDLILLDVLMPGIDGFETCQRLKA
VEATRDIPVIFMTALAEMDQKVRGFDAGAVDYIIKPLQREEVLARVGVHIHLRHLAKELQETNASLEKRVEDRTASLAST
NDELQKEIAERKLAEEALAIKQEQLEALNLSLEQRVIEEVEKNLQKDRLLFQNTRLAAMGELLNNIAHQWRQPLNKIALL
IQGCLYESNEGKLEHESFKSCVNRCMEHITYLSNTINSFQSFFMPEGEPGKFDPCETVEKSLALVRSSYEENGISVRIMN
NGSVPMMGFRNAFSQAVLSILNNAQQVLLERGTPQRLIEVECLYRDGKNIVTISDNGGGIDEKIIGKIFDPYFTTKFKAQ
GTGLGLYMAKMIIEKNMGGRLSARNTQAGAEFTIELPLPDS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=31.9502074688797, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082012, Length=155, Percent_Identity=34.8387096774194, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786599, Length=115, Percent_Identity=40, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786784, Length=112, Percent_Identity=30.3571428571429, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788550, Length=132, Percent_Identity=31.0606060606061, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788394, Length=135, Percent_Identity=31.8518518518519, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790437, Length=103, Percent_Identity=36.8932038834951, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=154, Percent_Identity=30.5194805194805, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=37.007874015748, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790860, Length=113, Percent_Identity=33.6283185840708, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=26.5217391304348, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=29.7101449275362, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786911, Length=122, Percent_Identity=32.7868852459016, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49316; Mature: 49316

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIIAQPKDHAAAILVIDDDANNLAIVSSLLQEYSYTIYVAEDGESGIRRALLTRPDLI
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCHH
LLDVLMPGIDGFETCQRLKAVEATRDIPVIFMTALAEMDQKVRGFDAGAVDYIIKPLQRE
HHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHH
EVLARVGVHIHLRHLAKELQETNASLEKRVEDRTASLASTNDELQKEIAERKLAEEALAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KQEQLEALNLSLEQRVIEEVEKNLQKDRLLFQNTRLAAMGELLNNIAHQWRQPLNKIALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IQGCLYESNEGKLEHESFKSCVNRCMEHITYLSNTINSFQSFFMPEGEPGKFDPCETVEK
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
SLALVRSSYEENGISVRIMNNGSVPMMGFRNAFSQAVLSILNNAQQVLLERGTPQRLIEV
HHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEE
ECLYRDGKNIVTISDNGGGIDEKIIGKIFDPYFTTKFKAQGTGLGLYMAKMIIEKNMGGR
EEEEECCCEEEEECCCCCCCCHHHHHHHHCCHHCCEEECCCCCHHHHHHHHHHHCCCCCC
LSARNTQAGAEFTIELPLPDS
CCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MNAIIAQPKDHAAAILVIDDDANNLAIVSSLLQEYSYTIYVAEDGESGIRRALLTRPDLI
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCHH
LLDVLMPGIDGFETCQRLKAVEATRDIPVIFMTALAEMDQKVRGFDAGAVDYIIKPLQRE
HHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHH
EVLARVGVHIHLRHLAKELQETNASLEKRVEDRTASLASTNDELQKEIAERKLAEEALAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KQEQLEALNLSLEQRVIEEVEKNLQKDRLLFQNTRLAAMGELLNNIAHQWRQPLNKIALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IQGCLYESNEGKLEHESFKSCVNRCMEHITYLSNTINSFQSFFMPEGEPGKFDPCETVEK
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
SLALVRSSYEENGISVRIMNNGSVPMMGFRNAFSQAVLSILNNAQQVLLERGTPQRLIEV
HHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEE
ECLYRDGKNIVTISDNGGGIDEKIIGKIFDPYFTTKFKAQGTGLGLYMAKMIIEKNMGGR
EEEEECCCEEEEECCCCCCCCHHHHHHHHCCHHCCEEECCCCCHHHHHHHHHHHCCCCCC
LSARNTQAGAEFTIELPLPDS
CCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]