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The map label for this gene is dgkA [H]

Identifier: 197117389

GI number: 197117389

Start: 1156754

End: 1157461

Strand: Direct

Name: dgkA [H]

Synonym: Gbem_0999

Alternate gene names: 197117389

Gene position: 1156754-1157461 (Clockwise)

Preceding gene: 308535206

Following gene: 197117390

Centisome position: 25.06

GC content: 61.72

Gene sequence:

>708_bases
ATGAAGCCCACGAGCTTCGTCGAATCGGTGAACTGCGCCATAGAGGGAATCCTCTACACGGCGCGGACGCAAAAGCACAT
GCGGCACCATTTTCTGGCCGCGTTGGTGGTGCTGGTCGCCGCCCTCCTCTTGCGGGTCACCCTGCTGGAGTTCATGCTGC
TGGCGCTCGCCATCAGCTTCGTGCTTTTTGCCGAGCTTTTGAACACCGCCATCGAGGTGGTGGTGGACATGATCTCCCCG
GAGTTCAACCCCATGGCCAAGCTTGCCAAGGACGTAGCGGCGGGCGCGGTTCTCGTGGCTGCCTTCGGGACGGCGATCAT
GGGATACCTGGTGCTGTCGAAGTACATTTTCCCGGTGGAAAAGAGGTTGCTTGCCATGGTCGGAACCGGTTCGGAGCTGG
GGATCCTTGTCTCCGTGATCCTGGTGCTCATCGCCGTCATCATACTGAAGGGGGTGACCGGCAGCGGCACGCCGCTCAAG
GGGGGAGTCCCCAGCGGCCACTCGGCGGTCGCCTTCTCCATCGCCACCTCGGTCACCCTGCAGACCCAGGACCCGCTCAT
CGCGCTTTTGTGCCTGATACTCGCCCTCATGGTGAGCCACTCAAGGCTTTTGCTGAAGATCCACACGGTGCGGGAACTCG
TGTACGGCGCGCTCACCGGCATCTCGATCACCGTGGCGGTGAACCTGCTATTCAACGCCTTCGCCTGA

Upstream 100 bases:

>100_bases
AAGCGGCGAGGCTGAGGCGGCCCGCATGGAGGCGAAGGAACGCGAGATCTTCGCCCTCTTGGTCGGGGAAGGTCTTGTCT
AGCGTCCGCAGGGGGAAGCG

Downstream 100 bases:

>100_bases
GAGGGAAGATCAAACGGTTAACGCAACAACGGAGGAGAAACGTCCTTGGAAGAGGATAACGGAAGCAAGGGGCAGGGCTT
GATCGAGTCCCTCACCAGGC

Product: diacylglycerol kinase-like protein

Products: NA

Alternate protein names: UdpK [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKPTSFVESVNCAIEGILYTARTQKHMRHHFLAALVVLVAALLLRVTLLEFMLLALAISFVLFAELLNTAIEVVVDMISP
EFNPMAKLAKDVAAGAVLVAAFGTAIMGYLVLSKYIFPVEKRLLAMVGTGSELGILVSVILVLIAVIILKGVTGSGTPLK
GGVPSGHSAVAFSIATSVTLQTQDPLIALLCLILALMVSHSRLLLKIHTVRELVYGALTGISITVAVNLLFNAFA

Sequences:

>Translated_235_residues
MKPTSFVESVNCAIEGILYTARTQKHMRHHFLAALVVLVAALLLRVTLLEFMLLALAISFVLFAELLNTAIEVVVDMISP
EFNPMAKLAKDVAAGAVLVAAFGTAIMGYLVLSKYIFPVEKRLLAMVGTGSELGILVSVILVLIAVIILKGVTGSGTPLK
GGVPSGHSAVAFSIATSVTLQTQDPLIALLCLILALMVSHSRLLLKIHTVRELVYGALTGISITVAVNLLFNAFA
>Mature_235_residues
MKPTSFVESVNCAIEGILYTARTQKHMRHHFLAALVVLVAALLLRVTLLEFMLLALAISFVLFAELLNTAIEVVVDMISP
EFNPMAKLAKDVAAGAVLVAAFGTAIMGYLVLSKYIFPVEKRLLAMVGTGSELGILVSVILVLIAVIILKGVTGSGTPLK
GGVPSGHSAVAFSIATSVTLQTQDPLIALLCLILALMVSHSRLLLKIHTVRELVYGALTGISITVAVNLLFNAFA

Specific function: Catalyzes the phosphorylation of undecaprenol, which is probably the primary physiological substrate. Is also able to phosphorylate diacylglycerol, albeit with very low efficiency. May play a role in adaptability to environmental stress conditions such as

COG id: COG0818

COG function: function code M; Diacylglycerol kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial diacylglycerol kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000829 [H]

Pfam domain/function: PF01219 DAGK_prokar [H]

EC number: =2.7.1.66 [H]

Molecular weight: Translated: 24893; Mature: 24893

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01069 DAGK_PROKAR ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTSFVESVNCAIEGILYTARTQKHMRHHFLAALVVLVAALLLRVTLLEFMLLALAISF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLFAELLNTAIEVVVDMISPEFNPMAKLAKDVAAGAVLVAAFGTAIMGYLVLSKYIFPVE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRLLAMVGTGSELGILVSVILVLIAVIILKGVTGSGTPLKGGVPSGHSAVAFSIATSVTL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEEE
QTQDPLIALLCLILALMVSHSRLLLKIHTVRELVYGALTGISITVAVNLLFNAFA
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPTSFVESVNCAIEGILYTARTQKHMRHHFLAALVVLVAALLLRVTLLEFMLLALAISF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLFAELLNTAIEVVVDMISPEFNPMAKLAKDVAAGAVLVAAFGTAIMGYLVLSKYIFPVE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRLLAMVGTGSELGILVSVILVLIAVIILKGVTGSGTPLKGGVPSGHSAVAFSIATSVTL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEEE
QTQDPLIALLCLILALMVSHSRLLLKIHTVRELVYGALTGISITVAVNLLFNAFA
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8407794; 9422608; 12397186 [H]