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The map label for this gene is rsbU [H]

Identifier: 197117365

GI number: 197117365

Start: 1132216

End: 1133766

Strand: Direct

Name: rsbU [H]

Synonym: Gbem_0975

Alternate gene names: 197117365

Gene position: 1132216-1133766 (Clockwise)

Preceding gene: 197117364

Following gene: 197117368

Centisome position: 24.53

GC content: 56.8

Gene sequence:

>1551_bases
ATGACGCAGCGATTGCGCATACTGCATCTAGAGGACGATCCGATGGATGCCGAACTCGTCTTGATGGCTCTTACCGCAGA
GGGGCTCGATTGTGAGGTCCAGGTGGTGTCGAGGCGGGATGAGTTCGACAAAGCTTTGCAGCGGGGTGGAATGGACCTCA
TTCTTGCCGACTTTGCGCTCCCTGCCTTTGACGGGATGAGCGCCTTGGCGATGGTCCGGGCCAAGCTTCCTGATCTGCCT
TTCGTCTTTGTCTCAGGCAAGCTTGGTGAAGAGGCGGCGATTGAGTCCCTTAAAAGCGGCGCCACCGACTACGTGCTCAA
AAGCAGGTTGTCCAGACTGGGGCCAGCGGTACAAAGGGCGCTAACTGAGGCAACGGAGCGCGCGAAGCAACGCCAAACCG
AGAAGGCGCTGGAGGTAGCATATGCTGAGATAGAGAAGCGGGCGGAGGACTACCGCAACCTCTTCAACAGCATCAGGGAC
GTCATCGTGGTGGCTGACCACAACCGGACGATCCTGCATGTCAATCAACCGGCACTCATTGACACGTTTGGCTACAGCTC
CGACGAGGTGGTGGGAGAAAGCAGCATCATCCTCTACGCGAATGAGGATGACTTCCACAGCACCGGAAAAGAAGTATTCG
ACGTGGAGGGACCGGTGGATGGAAAACTCATAGAGCTGAACTTCCGCAGGAAAGGCGGGGAAGTTTTCATCGGCGAACTT
TACGCGATGAAAAGGCTGGACCGGCACGGCGTGGTGACCGGCAACATCTCGATCTTCAGGGATATCAGCCAGCGCAAGAA
AGCTGAGGCAGATCTCAGGGAGAGTGAACTGCGACGCTACCAACTGCAATTGGAACTGGTTTACGCCGCGGAAATCCAGG
CAAAACTATTGCCGCGCAGTTATCCAAATATCCCCGGTTTTGATGTAAGCGCGAGGTGTCTGCCTGCGAAGCAGGTGGGA
GGGGATTTCTACGATTGGCAGCAGGTGACCCCCACCGTTTTCAATCTGACTCTTGGTGATGTGATGGGCAAGGGGATGGC
GGCGGCCATGCTCATGGCGACCGTTAGAGCGGCACTTCATGCCGTTACGCTGTACAACACACCCGCGCCGGCGGTGCACC
TGGCGGAAAAGGCGCTCAACGAGGATCTGGAGAATTCCGAGAGCTTTGTCACCCTTTTCCATGCCCAGCTCGACTCCGTT
ACACGCACCCTTTCCTTCGTCGATTGCGGTCATGGCTATGTCTTTGTCAGGAGAGCCACTGGCGCGGTGGAGACTCTCTC
GCCGAGAGGGCTTCCCCTGGGGGTGCAGGGGGGGGAAGTTTACCAGGAAGGGAAGGTACAGTTTGAAAAGGGGGATGTGT
TTGTTCTTTACAGCGATGGGCTCATCGACGCCAACCCGCAGCTCGAGTTGACCCATGAGATACTTGCCGGGCAGATTAGA
AGTGAGGAGGGCGCGCTGGAGACTGTGGATCGGCTCATTGCTCTCACTAGGCAGCCTGACCCGCAGCCTGACGACATAAC
CGTACTGGTGGCAAAATTTAACGGCGACTAA

Upstream 100 bases:

>100_bases
CGGTAAATTTCAACGAATTCATTACAGCTGTAAAGGAGATAGGCGCATTCTGGGCCATAGTGAACGAGCCGCCTCCGGTT
CAGCACAGAGGTGGGATCAG

Downstream 100 bases:

>100_bases
CCGATTCACTCCCCGATGATCTTGATCAAAACCCGCTTCCTGCGCATTCCGTCGAATTCCCCGTAAAACACCTGCTCCCA
GGGCCCCAGGTCGAGTTTTC

Product: response receiver sensor phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTQRLRILHLEDDPMDAELVLMALTAEGLDCEVQVVSRRDEFDKALQRGGMDLILADFALPAFDGMSALAMVRAKLPDLP
FVFVSGKLGEEAAIESLKSGATDYVLKSRLSRLGPAVQRALTEATERAKQRQTEKALEVAYAEIEKRAEDYRNLFNSIRD
VIVVADHNRTILHVNQPALIDTFGYSSDEVVGESSIILYANEDDFHSTGKEVFDVEGPVDGKLIELNFRRKGGEVFIGEL
YAMKRLDRHGVVTGNISIFRDISQRKKAEADLRESELRRYQLQLELVYAAEIQAKLLPRSYPNIPGFDVSARCLPAKQVG
GDFYDWQQVTPTVFNLTLGDVMGKGMAAAMLMATVRAALHAVTLYNTPAPAVHLAEKALNEDLENSESFVTLFHAQLDSV
TRTLSFVDCGHGYVFVRRATGAVETLSPRGLPLGVQGGEVYQEGKVQFEKGDVFVLYSDGLIDANPQLELTHEILAGQIR
SEEGALETVDRLIALTRQPDPQPDDITVLVAKFNGD

Sequences:

>Translated_516_residues
MTQRLRILHLEDDPMDAELVLMALTAEGLDCEVQVVSRRDEFDKALQRGGMDLILADFALPAFDGMSALAMVRAKLPDLP
FVFVSGKLGEEAAIESLKSGATDYVLKSRLSRLGPAVQRALTEATERAKQRQTEKALEVAYAEIEKRAEDYRNLFNSIRD
VIVVADHNRTILHVNQPALIDTFGYSSDEVVGESSIILYANEDDFHSTGKEVFDVEGPVDGKLIELNFRRKGGEVFIGEL
YAMKRLDRHGVVTGNISIFRDISQRKKAEADLRESELRRYQLQLELVYAAEIQAKLLPRSYPNIPGFDVSARCLPAKQVG
GDFYDWQQVTPTVFNLTLGDVMGKGMAAAMLMATVRAALHAVTLYNTPAPAVHLAEKALNEDLENSESFVTLFHAQLDSV
TRTLSFVDCGHGYVFVRRATGAVETLSPRGLPLGVQGGEVYQEGKVQFEKGDVFVLYSDGLIDANPQLELTHEILAGQIR
SEEGALETVDRLIALTRQPDPQPDDITVLVAKFNGD
>Mature_515_residues
TQRLRILHLEDDPMDAELVLMALTAEGLDCEVQVVSRRDEFDKALQRGGMDLILADFALPAFDGMSALAMVRAKLPDLPF
VFVSGKLGEEAAIESLKSGATDYVLKSRLSRLGPAVQRALTEATERAKQRQTEKALEVAYAEIEKRAEDYRNLFNSIRDV
IVVADHNRTILHVNQPALIDTFGYSSDEVVGESSIILYANEDDFHSTGKEVFDVEGPVDGKLIELNFRRKGGEVFIGELY
AMKRLDRHGVVTGNISIFRDISQRKKAEADLRESELRRYQLQLELVYAAEIQAKLLPRSYPNIPGFDVSARCLPAKQVGG
DFYDWQQVTPTVFNLTLGDVMGKGMAAAMLMATVRAALHAVTLYNTPAPAVHLAEKALNEDLENSESFVTLFHAQLDSVT
RTLSFVDCGHGYVFVRRATGAVETLSPRGLPLGVQGGEVYQEGKVQFEKGDVFVLYSDGLIDANPQLELTHEILAGQIRS
EEGALETVDRLIALTRQPDPQPDDITVLVAKFNGD

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 57060; Mature: 56928

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRLRILHLEDDPMDAELVLMALTAEGLDCEVQVVSRRDEFDKALQRGGMDLILADFAL
CCCCEEEEEECCCCCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCEEEEEHHCC
PAFDGMSALAMVRAKLPDLPFVFVSGKLGEEAAIESLKSGATDYVLKSRLSRLGPAVQRA
CCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHH
LTEATERAKQRQTEKALEVAYAEIEKRAEDYRNLFNSIRDVIVVADHNRTILHVNQPALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCEE
DTFGYSSDEVVGESSIILYANEDDFHSTGKEVFDVEGPVDGKLIELNFRRKGGEVFIGEL
EECCCCCCCEECCCEEEEEECCCCHHCCCCEEEECCCCCCCEEEEEEEECCCCCEEEHHH
YAMKRLDRHGVVTGNISIFRDISQRKKAEADLRESELRRYQLQLELVYAAEIQAKLLPRS
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEHHHHHHCCCC
YPNIPGFDVSARCLPAKQVGGDFYDWQQVTPTVFNLTLGDVMGKGMAAAMLMATVRAALH
CCCCCCCCCCCCCCCHHHHCCCCCCHHHCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHH
AVTLYNTPAPAVHLAEKALNEDLENSESFVTLFHAQLDSVTRTLSFVDCGHGYVFVRRAT
EEEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEECCCCEEEEEECC
GAVETLSPRGLPLGVQGGEVYQEGKVQFEKGDVFVLYSDGLIDANPQLELTHEILAGQIR
CCCCCCCCCCCEECCCCCCEEECCCEEEECCCEEEEEECCEECCCCCHHHHHHHHHHHHC
SEEGALETVDRLIALTRQPDPQPDDITVLVAKFNGD
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
TQRLRILHLEDDPMDAELVLMALTAEGLDCEVQVVSRRDEFDKALQRGGMDLILADFAL
CCCEEEEEECCCCCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCEEEEEHHCC
PAFDGMSALAMVRAKLPDLPFVFVSGKLGEEAAIESLKSGATDYVLKSRLSRLGPAVQRA
CCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHH
LTEATERAKQRQTEKALEVAYAEIEKRAEDYRNLFNSIRDVIVVADHNRTILHVNQPALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCEE
DTFGYSSDEVVGESSIILYANEDDFHSTGKEVFDVEGPVDGKLIELNFRRKGGEVFIGEL
EECCCCCCCEECCCEEEEEECCCCHHCCCCEEEECCCCCCCEEEEEEEECCCCCEEEHHH
YAMKRLDRHGVVTGNISIFRDISQRKKAEADLRESELRRYQLQLELVYAAEIQAKLLPRS
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEHHHHHHCCCC
YPNIPGFDVSARCLPAKQVGGDFYDWQQVTPTVFNLTLGDVMGKGMAAAMLMATVRAALH
CCCCCCCCCCCCCCCHHHHCCCCCCHHHCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHH
AVTLYNTPAPAVHLAEKALNEDLENSESFVTLFHAQLDSVTRTLSFVDCGHGYVFVRRAT
EEEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEECCCCEEEEEECC
GAVETLSPRGLPLGVQGGEVYQEGKVQFEKGDVFVLYSDGLIDANPQLELTHEILAGQIR
CCCCCCCCCCCEECCCCCCEEECCCEEEECCCEEEEEECCEECCCCCHHHHHHHHHHHHC
SEEGALETVDRLIALTRQPDPQPDDITVLVAKFNGD
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]