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The map label for this gene is ftsY [H]

Identifier: 197117354

GI number: 197117354

Start: 1116865

End: 1118094

Strand: Direct

Name: ftsY [H]

Synonym: Gbem_0964

Alternate gene names: 197117354

Gene position: 1116865-1118094 (Clockwise)

Preceding gene: 197117353

Following gene: 197117355

Centisome position: 24.2

GC content: 64.72

Gene sequence:

>1230_bases
ATGGCCGAGGACAACAGGGGCTTTTTCAAGGGACTGCTGAAGAAACTCGGTGTGGGGTCCGCAGAGGAACCCGTTCCCGC
TGATGAGGACGCGAAACAAGAAGGCGGGTCCGGCCAGGCGTCGACGGCCGAGGAGCAGCAGGTCCCGGTACAGCCGCAGC
AGCAGGAGCAGGCAGCACCGGTTGCGCCGCCCGAGCCCCCCGCACCGGCGGAGCCGGCACGCACCCCATGGGTCGAGCCC
TCTGCGCCGGCGTCGCGCCCTGCGTGGCATGAACCTGCCGTCGCGGTGCCGCCCCCCCCCGAGCCCGAGGCCGCCAAGCC
CAGCTTCTTCGAGCGCCTGAAAAAAAGCCTGAGCAAGACCCACGAGAGCATCGTCGGCCGGGTGGACACGCTGCTTTTAG
GCAAGAAGCAGATCGATACGGACACCCTTGAGGAGCTCGAGGAGATCCTGATTACGGCCGACCTCGGGGTGAAGACCACC
GTGGATCTGATCCGGACCCTGGAGCAGCGGCTGAAGAGGGACGAACTGCAGGACGGCGAGGCTCTGAAGAAAGCGCTGAA
GGAGGAAATCCAACTGCGCCTGATGGCCCATGCCGCGCCCCTTGTGGTGACCGACAAGAAACCGTTCGTGATCCTGGTGA
TAGGCGTGAACGGCGTCGGCAAGACCACGACCATCGGGAAGCTTGCTGCCCGCTACGCTGGGGAGGGGAAGAAGGTTCTC
CTGGCCGCAGCTGACACTTTCCGTGCTGCTGCCGCCGAACAGCTTGAGCTGTGGTCGCAGCGCGTCGGCGCCGACATCGT
GCGCCACAAGGAGGGGGCGGATCCCTCCGCCGTCGTCTTTGACGCCTGCAAGGCGGCCGTTGCGCGCGGCACCGATGTCC
TCATCATCGACACGGCGGGAAGGATGCACACCAAGGTGAACCTCATGGAGGAGATGAAGAAGATCCGCCGGGTGCTCACC
CGCGAGATCCCCGACGCCCCGCACGAGACTCTTTTGGTGCTGGACGCGGCCACAGGCCAGAACGCCCTGTCCCAGGCGAA
GCTTTTCAAGGAGGCCGCTTTCGTCTCCGGCGTGGTTCTCACCAAACTCGACGGCAGCGCCAAGGGTGGAGTTGTGGTGG
CGGTGAGTAATGAGTACGCGCTTCCGGTTCGATTCATTGGCGTGGGGGAGTCGGTCGATGACCTCCGGGAGTTCGATCCG
GCCCAGTTCGTGGAGGCTCTTTTCCAATAA

Upstream 100 bases:

>100_bases
ATTATTCCCTGGTCATGACCATGAACAAAAACGCACTGCCGCTCCTGGCGCTCAACAAGTTCCGGGAGACCGCGGCGCTT
TTGCATAAGGAGATCTATTG

Downstream 100 bases:

>100_bases
TTGCCTTGACTTTTGAGTACTTATTGCATAAGATTTCGCCGCAAAAGGTGCAATAATGAGTAACGACTTGTTTGATGAGC
TGGAGGGCCGGGTAGTTTCT

Product: signal recognition particle GTPase FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAEDNRGFFKGLLKKLGVGSAEEPVPADEDAKQEGGSGQASTAEEQQVPVQPQQQEQAAPVAPPEPPAPAEPARTPWVEP
SAPASRPAWHEPAVAVPPPPEPEAAKPSFFERLKKSLSKTHESIVGRVDTLLLGKKQIDTDTLEELEEILITADLGVKTT
VDLIRTLEQRLKRDELQDGEALKKALKEEIQLRLMAHAAPLVVTDKKPFVILVIGVNGVGKTTTIGKLAARYAGEGKKVL
LAAADTFRAAAAEQLELWSQRVGADIVRHKEGADPSAVVFDACKAAVARGTDVLIIDTAGRMHTKVNLMEEMKKIRRVLT
REIPDAPHETLLVLDAATGQNALSQAKLFKEAAFVSGVVLTKLDGSAKGGVVVAVSNEYALPVRFIGVGESVDDLREFDP
AQFVEALFQ

Sequences:

>Translated_409_residues
MAEDNRGFFKGLLKKLGVGSAEEPVPADEDAKQEGGSGQASTAEEQQVPVQPQQQEQAAPVAPPEPPAPAEPARTPWVEP
SAPASRPAWHEPAVAVPPPPEPEAAKPSFFERLKKSLSKTHESIVGRVDTLLLGKKQIDTDTLEELEEILITADLGVKTT
VDLIRTLEQRLKRDELQDGEALKKALKEEIQLRLMAHAAPLVVTDKKPFVILVIGVNGVGKTTTIGKLAARYAGEGKKVL
LAAADTFRAAAAEQLELWSQRVGADIVRHKEGADPSAVVFDACKAAVARGTDVLIIDTAGRMHTKVNLMEEMKKIRRVLT
REIPDAPHETLLVLDAATGQNALSQAKLFKEAAFVSGVVLTKLDGSAKGGVVVAVSNEYALPVRFIGVGESVDDLREFDP
AQFVEALFQ
>Mature_408_residues
AEDNRGFFKGLLKKLGVGSAEEPVPADEDAKQEGGSGQASTAEEQQVPVQPQQQEQAAPVAPPEPPAPAEPARTPWVEPS
APASRPAWHEPAVAVPPPPEPEAAKPSFFERLKKSLSKTHESIVGRVDTLLLGKKQIDTDTLEELEEILITADLGVKTTV
DLIRTLEQRLKRDELQDGEALKKALKEEIQLRLMAHAAPLVVTDKKPFVILVIGVNGVGKTTTIGKLAARYAGEGKKVLL
AAADTFRAAAAEQLELWSQRVGADIVRHKEGADPSAVVFDACKAAVARGTDVLIIDTAGRMHTKVNLMEEMKKIRRVLTR
EIPDAPHETLLVLDAATGQNALSQAKLFKEAAFVSGVVLTKLDGSAKGGVVVAVSNEYALPVRFIGVGESVDDLREFDPA
QFVEALFQ

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=270, Percent_Identity=31.1111111111111, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226371618, Length=205, Percent_Identity=34.6341463414634, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI295424842, Length=317, Percent_Identity=26.813880126183, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI23308697, Length=317, Percent_Identity=26.813880126183, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=32.5925925925926, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789874, Length=327, Percent_Identity=52.2935779816514, Blast_Score=307, Evalue=8e-85,
Organism=Escherichia coli, GI1788963, Length=300, Percent_Identity=35, Blast_Score=157, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=270, Percent_Identity=30, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI193206261, Length=311, Percent_Identity=29.5819935691318, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=311, Percent_Identity=29.903536977492, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320498, Length=222, Percent_Identity=31.0810810810811, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17647949, Length=274, Percent_Identity=30.2919708029197, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24641198, Length=227, Percent_Identity=29.9559471365639, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 43957; Mature: 43825

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEDNRGFFKGLLKKLGVGSAEEPVPADEDAKQEGGSGQASTAEEQQVPVQPQQQEQAAP
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHCCCCCCCHHHCCCC
VAPPEPPAPAEPARTPWVEPSAPASRPAWHEPAVAVPPPPEPEAAKPSFFERLKKSLSKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHH
HESIVGRVDTLLLGKKQIDTDTLEELEEILITADLGVKTTVDLIRTLEQRLKRDELQDGE
HHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCH
ALKKALKEEIQLRLMAHAAPLVVTDKKPFVILVIGVNGVGKTTTIGKLAARYAGEGKKVL
HHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEE
LAAADTFRAAAAEQLELWSQRVGADIVRHKEGADPSAVVFDACKAAVARGTDVLIIDTAG
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
RMHTKVNLMEEMKKIRRVLTREIPDAPHETLLVLDAATGQNALSQAKLFKEAAFVSGVVL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEE
TKLDGSAKGGVVVAVSNEYALPVRFIGVGESVDDLREFDPAQFVEALFQ
EECCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHC
>Mature Secondary Structure 
AEDNRGFFKGLLKKLGVGSAEEPVPADEDAKQEGGSGQASTAEEQQVPVQPQQQEQAAP
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHCCCCCCCHHHCCCC
VAPPEPPAPAEPARTPWVEPSAPASRPAWHEPAVAVPPPPEPEAAKPSFFERLKKSLSKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHH
HESIVGRVDTLLLGKKQIDTDTLEELEEILITADLGVKTTVDLIRTLEQRLKRDELQDGE
HHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCH
ALKKALKEEIQLRLMAHAAPLVVTDKKPFVILVIGVNGVGKTTTIGKLAARYAGEGKKVL
HHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEE
LAAADTFRAAAAEQLELWSQRVGADIVRHKEGADPSAVVFDACKAAVARGTDVLIIDTAG
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
RMHTKVNLMEEMKKIRRVLTREIPDAPHETLLVLDAATGQNALSQAKLFKEAAFVSGVVL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEE
TKLDGSAKGGVVVAVSNEYALPVRFIGVGESVDDLREFDPAQFVEALFQ
EECCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]