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The map label for this gene is qmcA [H]

Identifier: 197116724

GI number: 197116724

Start: 395561

End: 396415

Strand: Direct

Name: qmcA [H]

Synonym: Gbem_0324

Alternate gene names: 197116724

Gene position: 395561-396415 (Clockwise)

Preceding gene: 197116723

Following gene: 197116725

Centisome position: 8.57

GC content: 55.09

Gene sequence:

>855_bases
ATGGAACCAGCAGCAGTAGTGTTCGCAATATTGTTTTTAGTCGTCGTAGTGACCATCTTCATGGGCGTGCGGCTCGTCCC
GCAGGGGTTCGAGTTCGTTGTGCAGCGTCTCGGGAAGTATCACTCCACACTTAAGCCCGGTCTCAATTTCATCATTCCAT
ACGTCGACATCGTCGCCTACCGTCTGACCACCAAGGACATCCCGCTGGAAATCGGCGCACAGGAAGCCATCACCAAGGAC
AACGCCGTCATCGTAGCTAACGCCATCGCCTTCATCAAGATCGTAGATCCCGTAAAGGCAGTGTATGGCATCAGCAACTA
CGAGTACGCCATCCAGAACCTCGTCATGACCTCGCTGCGCGCCATCATCGGCGAGATGGAACTGGACCTCGCCCTCTCCT
CGCGGGACATCATAAAGGCTCGCCTGAAGGACATCATCTCCGATGACGTCACCGACTGGGGCATCCTGGTGAAATCAGTA
GAGATACAAGACATCAAGCCGTCCGAGTCCATGCAAAAGGCGATGGAGCAGCAAGCGACTGCCGAGCGGTTGAAGCGCGC
CATGATTCTGGAAGCAGAAGGTAAAAAAGAAGCGATGATCCGAGAAGCCGAGGGCAAGCTCGAAGCAGCGAAGAAAGAAG
CCGAAGCCCAGATGATGTTAGCCGAAGCGTCCGCCAAGGCCATCGAAGACATTGCCGTAGCAGTAGGCGACAAAGAGCTC
CCCGCCCTTTTCCTCCTTGGCGACCGCTATGTGAATGCCATTCAGAAGCTCTCCACCTCGCCCAACACGAAAAACTTCGT
GTTGCCGGCAGACATACTTGGTGCCGTAAAGGGGATTGCCGGAAGAAGCGTCTAG

Upstream 100 bases:

>100_bases
GTGTGGCCGATGATCCTTTAGCGGTTGGAGATCGCGTCCGGGTAGTCGACGTGGAAGGACATGTCATGAAGGTCGAAAAA
ATAGCAAAAGGGGATAAGTG

Downstream 100 bases:

>100_bases
TTAACCTCGTTGACAGCCGCGATGGGAATTCCGGGGAAACAGCAAATGAGTGCCCCCCTGGCTTATTTATCCATCATCTT
TGCAGCTCATACCCTTTAAA

Product: flotillin band_7_stomatin-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MEPAAVVFAILFLVVVVTIFMGVRLVPQGFEFVVQRLGKYHSTLKPGLNFIIPYVDIVAYRLTTKDIPLEIGAQEAITKD
NAVIVANAIAFIKIVDPVKAVYGISNYEYAIQNLVMTSLRAIIGEMELDLALSSRDIIKARLKDIISDDVTDWGILVKSV
EIQDIKPSESMQKAMEQQATAERLKRAMILEAEGKKEAMIREAEGKLEAAKKEAEAQMMLAEASAKAIEDIAVAVGDKEL
PALFLLGDRYVNAIQKLSTSPNTKNFVLPADILGAVKGIAGRSV

Sequences:

>Translated_284_residues
MEPAAVVFAILFLVVVVTIFMGVRLVPQGFEFVVQRLGKYHSTLKPGLNFIIPYVDIVAYRLTTKDIPLEIGAQEAITKD
NAVIVANAIAFIKIVDPVKAVYGISNYEYAIQNLVMTSLRAIIGEMELDLALSSRDIIKARLKDIISDDVTDWGILVKSV
EIQDIKPSESMQKAMEQQATAERLKRAMILEAEGKKEAMIREAEGKLEAAKKEAEAQMMLAEASAKAIEDIAVAVGDKEL
PALFLLGDRYVNAIQKLSTSPNTKNFVLPADILGAVKGIAGRSV
>Mature_284_residues
MEPAAVVFAILFLVVVVTIFMGVRLVPQGFEFVVQRLGKYHSTLKPGLNFIIPYVDIVAYRLTTKDIPLEIGAQEAITKD
NAVIVANAIAFIKIVDPVKAVYGISNYEYAIQNLVMTSLRAIIGEMELDLALSSRDIIKARLKDIISDDVTDWGILVKSV
EIQDIKPSESMQKAMEQQATAERLKRAMILEAEGKKEAMIREAEGKLEAAKKEAEAQMMLAEASAKAIEDIAVAVGDKEL
PALFLLGDRYVNAIQKLSTSPNTKNFVLPADILGAVKGIAGRSV

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=266, Percent_Identity=33.0827067669173, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI221316744, Length=285, Percent_Identity=28.0701754385965, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI21686995, Length=285, Percent_Identity=28.0701754385965, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI38016911, Length=279, Percent_Identity=29.3906810035842, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7657615, Length=286, Percent_Identity=23.4265734265734, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786697, Length=290, Percent_Identity=37.2413793103448, Blast_Score=213, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI32564147, Length=271, Percent_Identity=35.4243542435424, Blast_Score=160, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17569493, Length=195, Percent_Identity=32.8205128205128, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193209764, Length=195, Percent_Identity=32.8205128205128, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17569497, Length=196, Percent_Identity=29.0816326530612, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17570459, Length=196, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71989955, Length=187, Percent_Identity=32.0855614973262, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71989948, Length=187, Percent_Identity=32.0855614973262, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17542664, Length=167, Percent_Identity=29.3413173652695, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566490, Length=184, Percent_Identity=27.7173913043478, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25153583, Length=194, Percent_Identity=26.8041237113402, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71987612, Length=194, Percent_Identity=26.8041237113402, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71987621, Length=194, Percent_Identity=26.8041237113402, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569499, Length=198, Percent_Identity=29.7979797979798, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193210507, Length=197, Percent_Identity=26.3959390862944, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17570161, Length=197, Percent_Identity=26.3959390862944, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550506, Length=283, Percent_Identity=33.9222614840989, Blast_Score=160, Evalue=8e-40,
Organism=Drosophila melanogaster, GI21356845, Length=195, Percent_Identity=29.2307692307692, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18860517, Length=202, Percent_Identity=29.7029702970297, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281361631, Length=198, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281361633, Length=198, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45556022, Length=212, Percent_Identity=29.2452830188679, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28573263, Length=262, Percent_Identity=25.9541984732824, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI62484448, Length=272, Percent_Identity=26.8382352941176, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI62484274, Length=272, Percent_Identity=26.8382352941176, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281365664, Length=272, Percent_Identity=26.8382352941176, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24657857, Length=272, Percent_Identity=26.8382352941176, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281361635, Length=125, Percent_Identity=28.8, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 31033; Mature: 31033

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPAAVVFAILFLVVVVTIFMGVRLVPQGFEFVVQRLGKYHSTLKPGLNFIIPYVDIVAY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RLTTKDIPLEIGAQEAITKDNAVIVANAIAFIKIVDPVKAVYGISNYEYAIQNLVMTSLR
HHCCCCCCCCCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AIIGEMELDLALSSRDIIKARLKDIISDDVTDWGILVKSVEIQDIKPSESMQKAMEQQAT
HHHHHHHHHHECCHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHH
AERLKRAMILEAEGKKEAMIREAEGKLEAAKKEAEAQMMLAEASAKAIEDIAVAVGDKEL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PALFLLGDRYVNAIQKLSTSPNTKNFVLPADILGAVKGIAGRSV
CEEEEEHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEPAAVVFAILFLVVVVTIFMGVRLVPQGFEFVVQRLGKYHSTLKPGLNFIIPYVDIVAY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RLTTKDIPLEIGAQEAITKDNAVIVANAIAFIKIVDPVKAVYGISNYEYAIQNLVMTSLR
HHCCCCCCCCCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AIIGEMELDLALSSRDIIKARLKDIISDDVTDWGILVKSVEIQDIKPSESMQKAMEQQAT
HHHHHHHHHHECCHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHH
AERLKRAMILEAEGKKEAMIREAEGKLEAAKKEAEAQMMLAEASAKAIEDIAVAVGDKEL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PALFLLGDRYVNAIQKLSTSPNTKNFVLPADILGAVKGIAGRSV
CEEEEEHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]