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The map label for this gene is pyc [H]

Identifier: 197116673

GI number: 197116673

Start: 327415

End: 330861

Strand: Reverse

Name: pyc [H]

Synonym: Gbem_0273

Alternate gene names: 197116673

Gene position: 330861-327415 (Counterclockwise)

Preceding gene: 197116685

Following gene: 197116672

Centisome position: 7.17

GC content: 64.08

Gene sequence:

>3447_bases
ATGGAAGCAAGGAAATTCAGGAAAGTGATGGCGGCAAACCGCGGAGAGATCGCAATCAGGATCTTCCGCGCCTGCACCGA
GCTCGGCATCAGCACGGTGGCCATCTACTCGGAAGAGGACAAGCTATCCCTGCACCGCTACAAGGCGGACGAGGCGTACC
TGGTCGGCAAGGGGAAAGCGCCCATCGACGCCTACCTCGGCATCGACGAGATCATCGCGCTGGCGAAGAAGCGCGAAGTC
GACGCCATTCACCCGGGCTACGGGTTCCTTGCCGAAAATGCCGAATTCGCCGAGAAATGCGAGGCCAACGGCATCGCCTT
CATCGGACCGACCGCCGAGATGCAGCGCGCCCTGGGCGACAAGGTCGCCGCCAGGAAGGTCGCCAAGGCGGCGGGCGTCA
CCACCGTGCCCGGGACCGAGGAGCCGATCACCCACGAGGAAGACGCCCTCATCTTCGCCAAGAATCACGGCTACCCCATC
ATCATCAAGGCGGCGGCGGGAGGCGGCGGCCGCGGCATGCGCGTCGCCACCGACAAGAAGGAACTCCTGGAGGGGCTGCA
GTCCGCCTCCAGCGAGGCAAAGGCCGCCTTCGGCGACCCTTCCGTCTTCCTGGAGCGCTACCTGAAAAACCCCAAGCACA
TCGAGGTGCAGGTTCTGGGCGACGCCTACGGGAACCTGGTGCACTTCTACGAGCGCGACTGCTCGATCCAGCGCCGCCAC
CAAAAGGTGGTCGAATTCGCGCCGTCGCTGGCGCTTCCCGGCGCCACCCGCTTAGCGCTTTGCACCGACGCGCTGAAGAT
AGCGAACCAGGTGGGGTACCGTAACGCCGGCACCGTGGAGTTCCTGCTCGACGAGGACGGCAAGTACTACTTCATCGAGA
TGAACCCCCGCATACAGGTGGAGCACACGGTGACCGAGATGATCACCGGCAGAAACCTGGTGCAGGCCCAGATCCTGATC
GCGGAAGGGAAGAGGCTCTCCGACCCGGAGATCAACATCCCGAATCAGGGGTCCATCGAGATGCGCGGCTACGCCATCCA
GTGTCGCATTACCACCGAGGACCCGGGGAACAACTTCGCCCCCGACTTCGGGACGCTCTCCACCTACCGCTCCTCGGCCG
GATGCGGCGTGCGCCTTGACGCCGGTAACGCCTTCACCGGCGCCCAGATCACCCCGCATTACGACTCGCTGCTGGTCAAG
GTGAGCGCCTGGGGCCTTACCTTCGCCGAGGCCGCGCACATCATGGACCGAAGCCTCCAGGAGTTCAGGGTGCGCGGGGT
GAAGACCAACATCGGCTTCCTGGAGAACGTGATCACGCACCCGGTGTTCCTCGCGGGGGGCTGCAACACCTCGTTCATCG
ACCAGCACCCCGAGCTCCTCGTCATCCCGGAGAAGAAGGACCGCGCCAACAAGGTGCTGCAGTTCCTGGGGGACGTCATC
GTCAACGGCTCCCCGGGGGTCGCGAAGCCTTTGCGCTCCGCGGAGCTCATCGAGGCCACCGTGCCGCAGATCGCCCCCTT
CGCCCAAAGGCCGAAAGGGACCCGCGACATCCTGCGCGAGAAGGGTGCCGAGGGGCTTTCCAAGTGGGTCATGGAACAAA
ATCACCTGCTCTTGACCGACACCACCATGCGCGACGCGCACCAGTCGCTGCTGGCCACCCGCGTCAGAACCCACGACCTG
TTGAAGATCGCCGAGCCGACCTCGCACCTGGCCAGCGACCTCTTCTCGCTGGAACTCTGGGGCGGGGCGACCTTCGACGT
CACCATGCGCTTTTTGAAGGAAGACCCCTGGCAGAGGCTGCACGCGCTCTCCGAGGCGATCCCCAACGTGCTGTTCCAGA
TGCTCCTTCGCGGCTCCAACGCCGTGGGGTACACCAACTACCCGGACAACGTGGTGCAGCGCTTCGTGGCCCAGGCGGCC
GAATCCGGCGTCGACGTCTTCCGCGTCTTCGACTCGCTCAACTGGACCCGCGGCATGCAGGTGGCCATGGAGGCGGTGCA
GAAATCGGGCAAGATCTGCGAGGCCGCCATCTGCTACACCGGCGACATCTCCGACCCCACCCGCACCAAGTACCCTCTCT
CCTACTACGTCTCCATGGCAAAGGAGCTGGAGAAGATGGGGGCGCACATCCTCGCCATCAAGGACATGGCCGGGCTCCTG
AAGCCGTACGCCGGCTACCAGCTGGTCAAGGCGCTCAAGGAGGAGATCGGCATCCCGGTGCACCTGCACACCCACGACAC
CTCCGGAAACGGCGGCGCCCTCCTCGTGATGGCGGCGCAGGCGGGTGTCGACATCGTCGACGCGGCGCTTTCCTCCATCT
CCGGCCTCACCTCGCAGCCCAACCTGAACGCGCTGGTGGCGACCCTCAAGGGGACCGAGCTCGATCCCAAGGTGAACGAG
CACGGCCTGCAGCAGCTCGCCAACTACTGGGAGACGGTGCGCGACTTCTACGCCCCGTTCGAATCCGGGCTCAAAAGCGG
CACCGCCGAGGTGTACCACCACGAGATCCCGGGCGGGCAGTACTCCAACTACAAGCCGCAGGTCGCGGGACTCGGGCTTT
TGGAGCGCTGGGAAGAGTGCAAGGAGATGTACCACAAGGTAAACGTGCTCTTCGGCGACGTGGTGAAGGTGACCCCTTCC
TCCAAGGTCGTCGGCGACATGGCGATGTTCCTGGTCAAGAACAACCTGGAGCCCGCAGACGTCTTCGTGCCGGGCGCGGA
TCTCGCCTTCCCCGAGTCGGTGGTCGGCTTCTTCAAGGGGATGATCGGCCAACCGTACCAGGGGTTCCCCGAGGAGCTGC
AGAAGATCGTCCTGAAAGGGCAGGAGCCCATCACCTGCCGCCCGGGCGAGCTCCTGGAGCCGACGGATTTCGAGAAGGAG
CGCGCCACGGCTGAAGCCAAGGCGGGGCACCCGGTGAACGACGAGGAACTGATGTCCTACATCATGTACCCGAGCGTCTA
CGTCGAATACGCGAAGCACCGCCAGGAGTACTCCGACGTCTCCGTGATCCCGACCCCGGTCTTCTTCTACGGCCTTGAGC
CGGGGCAGGAGACCTCCATCGAGCTCCAGCCCGGAAAGACCTTGATCGTCAAGCTGAATGCGGTCGGCAAGACCCAGCCC
GACGGCACCAAGCAGATCTACTTCGAGCTCAACGGCAACTCAAGGAGCGTCACCGTGCGCGACCAGTCGGTGCAAAGCGA
CGACTGCGGCCACGAAAAGGCCGACAAGTCGAACCCCAAGCACGTAGGGGTGCCGATGCCGGGGAAGGTGATCAAGATGA
ACGTGAAGACCGGCGACTCCGTCAAGGCGGGGGATATCCTCGCCGTCACCGAGGCCATGAAGATGGAGACCAACATCAAG
GCCAAGGAAGACGGGACCGTCTTCGAGGTGCGCTGCAAGGAGGGGGGCAAGGTCGAGAAAGAGGAACTTCTGATCGTGAT
GGCCTGA

Upstream 100 bases:

>100_bases
AAATTGGCTTTACCAATCTGGCCACTTTGTTTTATTCTCGTAAAAAAATTGCCCTCAAACTTTTACTCACGGTAAAAAAA
TTACCCCCAAAGGAGAAGCA

Downstream 100 bases:

>100_bases
CTTTTGAGACATAAATGAAGTGGAAAAGGGGGGCGGCCGCCCCCCTTTTTTTACGCCGTGCCCAAGCGTCAATGGAATGT
CAGAGCCCCATTCCGCGCGG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1148

Protein sequence:

>1148_residues
MEARKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKAPIDAYLGIDEIIALAKKREV
DAIHPGYGFLAENAEFAEKCEANGIAFIGPTAEMQRALGDKVAARKVAKAAGVTTVPGTEEPITHEEDALIFAKNHGYPI
IIKAAAGGGGRGMRVATDKKELLEGLQSASSEAKAAFGDPSVFLERYLKNPKHIEVQVLGDAYGNLVHFYERDCSIQRRH
QKVVEFAPSLALPGATRLALCTDALKIANQVGYRNAGTVEFLLDEDGKYYFIEMNPRIQVEHTVTEMITGRNLVQAQILI
AEGKRLSDPEINIPNQGSIEMRGYAIQCRITTEDPGNNFAPDFGTLSTYRSSAGCGVRLDAGNAFTGAQITPHYDSLLVK
VSAWGLTFAEAAHIMDRSLQEFRVRGVKTNIGFLENVITHPVFLAGGCNTSFIDQHPELLVIPEKKDRANKVLQFLGDVI
VNGSPGVAKPLRSAELIEATVPQIAPFAQRPKGTRDILREKGAEGLSKWVMEQNHLLLTDTTMRDAHQSLLATRVRTHDL
LKIAEPTSHLASDLFSLELWGGATFDVTMRFLKEDPWQRLHALSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVAQAA
ESGVDVFRVFDSLNWTRGMQVAMEAVQKSGKICEAAICYTGDISDPTRTKYPLSYYVSMAKELEKMGAHILAIKDMAGLL
KPYAGYQLVKALKEEIGIPVHLHTHDTSGNGGALLVMAAQAGVDIVDAALSSISGLTSQPNLNALVATLKGTELDPKVNE
HGLQQLANYWETVRDFYAPFESGLKSGTAEVYHHEIPGGQYSNYKPQVAGLGLLERWEECKEMYHKVNVLFGDVVKVTPS
SKVVGDMAMFLVKNNLEPADVFVPGADLAFPESVVGFFKGMIGQPYQGFPEELQKIVLKGQEPITCRPGELLEPTDFEKE
RATAEAKAGHPVNDEELMSYIMYPSVYVEYAKHRQEYSDVSVIPTPVFFYGLEPGQETSIELQPGKTLIVKLNAVGKTQP
DGTKQIYFELNGNSRSVTVRDQSVQSDDCGHEKADKSNPKHVGVPMPGKVIKMNVKTGDSVKAGDILAVTEAMKMETNIK
AKEDGTVFEVRCKEGGKVEKEELLIVMA

Sequences:

>Translated_1148_residues
MEARKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKAPIDAYLGIDEIIALAKKREV
DAIHPGYGFLAENAEFAEKCEANGIAFIGPTAEMQRALGDKVAARKVAKAAGVTTVPGTEEPITHEEDALIFAKNHGYPI
IIKAAAGGGGRGMRVATDKKELLEGLQSASSEAKAAFGDPSVFLERYLKNPKHIEVQVLGDAYGNLVHFYERDCSIQRRH
QKVVEFAPSLALPGATRLALCTDALKIANQVGYRNAGTVEFLLDEDGKYYFIEMNPRIQVEHTVTEMITGRNLVQAQILI
AEGKRLSDPEINIPNQGSIEMRGYAIQCRITTEDPGNNFAPDFGTLSTYRSSAGCGVRLDAGNAFTGAQITPHYDSLLVK
VSAWGLTFAEAAHIMDRSLQEFRVRGVKTNIGFLENVITHPVFLAGGCNTSFIDQHPELLVIPEKKDRANKVLQFLGDVI
VNGSPGVAKPLRSAELIEATVPQIAPFAQRPKGTRDILREKGAEGLSKWVMEQNHLLLTDTTMRDAHQSLLATRVRTHDL
LKIAEPTSHLASDLFSLELWGGATFDVTMRFLKEDPWQRLHALSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVAQAA
ESGVDVFRVFDSLNWTRGMQVAMEAVQKSGKICEAAICYTGDISDPTRTKYPLSYYVSMAKELEKMGAHILAIKDMAGLL
KPYAGYQLVKALKEEIGIPVHLHTHDTSGNGGALLVMAAQAGVDIVDAALSSISGLTSQPNLNALVATLKGTELDPKVNE
HGLQQLANYWETVRDFYAPFESGLKSGTAEVYHHEIPGGQYSNYKPQVAGLGLLERWEECKEMYHKVNVLFGDVVKVTPS
SKVVGDMAMFLVKNNLEPADVFVPGADLAFPESVVGFFKGMIGQPYQGFPEELQKIVLKGQEPITCRPGELLEPTDFEKE
RATAEAKAGHPVNDEELMSYIMYPSVYVEYAKHRQEYSDVSVIPTPVFFYGLEPGQETSIELQPGKTLIVKLNAVGKTQP
DGTKQIYFELNGNSRSVTVRDQSVQSDDCGHEKADKSNPKHVGVPMPGKVIKMNVKTGDSVKAGDILAVTEAMKMETNIK
AKEDGTVFEVRCKEGGKVEKEELLIVMA
>Mature_1148_residues
MEARKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKAPIDAYLGIDEIIALAKKREV
DAIHPGYGFLAENAEFAEKCEANGIAFIGPTAEMQRALGDKVAARKVAKAAGVTTVPGTEEPITHEEDALIFAKNHGYPI
IIKAAAGGGGRGMRVATDKKELLEGLQSASSEAKAAFGDPSVFLERYLKNPKHIEVQVLGDAYGNLVHFYERDCSIQRRH
QKVVEFAPSLALPGATRLALCTDALKIANQVGYRNAGTVEFLLDEDGKYYFIEMNPRIQVEHTVTEMITGRNLVQAQILI
AEGKRLSDPEINIPNQGSIEMRGYAIQCRITTEDPGNNFAPDFGTLSTYRSSAGCGVRLDAGNAFTGAQITPHYDSLLVK
VSAWGLTFAEAAHIMDRSLQEFRVRGVKTNIGFLENVITHPVFLAGGCNTSFIDQHPELLVIPEKKDRANKVLQFLGDVI
VNGSPGVAKPLRSAELIEATVPQIAPFAQRPKGTRDILREKGAEGLSKWVMEQNHLLLTDTTMRDAHQSLLATRVRTHDL
LKIAEPTSHLASDLFSLELWGGATFDVTMRFLKEDPWQRLHALSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVAQAA
ESGVDVFRVFDSLNWTRGMQVAMEAVQKSGKICEAAICYTGDISDPTRTKYPLSYYVSMAKELEKMGAHILAIKDMAGLL
KPYAGYQLVKALKEEIGIPVHLHTHDTSGNGGALLVMAAQAGVDIVDAALSSISGLTSQPNLNALVATLKGTELDPKVNE
HGLQQLANYWETVRDFYAPFESGLKSGTAEVYHHEIPGGQYSNYKPQVAGLGLLERWEECKEMYHKVNVLFGDVVKVTPS
SKVVGDMAMFLVKNNLEPADVFVPGADLAFPESVVGFFKGMIGQPYQGFPEELQKIVLKGQEPITCRPGELLEPTDFEKE
RATAEAKAGHPVNDEELMSYIMYPSVYVEYAKHRQEYSDVSVIPTPVFFYGLEPGQETSIELQPGKTLIVKLNAVGKTQP
DGTKQIYFELNGNSRSVTVRDQSVQSDDCGHEKADKSNPKHVGVPMPGKVIKMNVKTGDSVKAGDILAVTEAMKMETNIK
AKEDGTVFEVRCKEGGKVEKEELLIVMA

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1148, Percent_Identity=51.6550522648084, Blast_Score=1140, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1148, Percent_Identity=51.6550522648084, Blast_Score=1140, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1148, Percent_Identity=51.6550522648084, Blast_Score=1140, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=466, Percent_Identity=43.1330472103004, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI189095269, Length=459, Percent_Identity=44.4444444444444, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI65506442, Length=459, Percent_Identity=44.4444444444444, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI295821183, Length=459, Percent_Identity=44.4444444444444, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI134142062, Length=508, Percent_Identity=32.8740157480315, Blast_Score=235, Evalue=2e-61,
Organism=Homo sapiens, GI38679960, Length=505, Percent_Identity=32.0792079207921, Blast_Score=233, Evalue=6e-61,
Organism=Homo sapiens, GI38679977, Length=505, Percent_Identity=32.0792079207921, Blast_Score=233, Evalue=7e-61,
Organism=Homo sapiens, GI38679967, Length=505, Percent_Identity=32.0792079207921, Blast_Score=233, Evalue=7e-61,
Organism=Homo sapiens, GI38679974, Length=505, Percent_Identity=32.0792079207921, Blast_Score=233, Evalue=7e-61,
Organism=Homo sapiens, GI38679971, Length=505, Percent_Identity=32.0792079207921, Blast_Score=233, Evalue=8e-61,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=45.43429844098, Blast_Score=357, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17562816, Length=1149, Percent_Identity=51.0879025239339, Blast_Score=1162, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=458, Percent_Identity=42.3580786026201, Blast_Score=356, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI17567343, Length=458, Percent_Identity=40.8296943231441, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI71997168, Length=439, Percent_Identity=31.8906605922551, Blast_Score=221, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71997163, Length=441, Percent_Identity=31.7460317460317, Blast_Score=221, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI133931226, Length=495, Percent_Identity=30.1010101010101, Blast_Score=209, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1159, Percent_Identity=50.1294219154443, Blast_Score=1114, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1159, Percent_Identity=50.3019844693701, Blast_Score=1106, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=452, Percent_Identity=38.716814159292, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6324343, Length=523, Percent_Identity=30.5927342256214, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323863, Length=449, Percent_Identity=33.4075723830735, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24652212, Length=1153, Percent_Identity=50.9973980919341, Blast_Score=1145, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1153, Percent_Identity=50.9973980919341, Blast_Score=1145, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1153, Percent_Identity=50.9973980919341, Blast_Score=1145, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1153, Percent_Identity=50.9973980919341, Blast_Score=1145, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1153, Percent_Identity=50.9973980919341, Blast_Score=1145, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1137, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1137, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1137, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1137, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1137, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=508, Percent_Identity=40.3543307086614, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24651759, Length=466, Percent_Identity=40.1287553648069, Blast_Score=326, Evalue=5e-89,
Organism=Drosophila melanogaster, GI161076409, Length=516, Percent_Identity=30.8139534883721, Blast_Score=221, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24586458, Length=516, Percent_Identity=30.8139534883721, Blast_Score=221, Evalue=2e-57,
Organism=Drosophila melanogaster, GI161076407, Length=516, Percent_Identity=30.8139534883721, Blast_Score=221, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24586460, Length=516, Percent_Identity=30.8139534883721, Blast_Score=221, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 125928; Mature: 125928

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKA
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEEEECCCC
PIDAYLGIDEIIALAKKREVDAIHPGYGFLAENAEFAEKCEANGIAFIGPTAEMQRALGD
CHHHHCCHHHHHHHHHHCCCCEECCCCCEEECCCHHHHHHCCCCEEEECCHHHHHHHHHH
KVAARKVAKAAGVTTVPGTEEPITHEEDALIFAKNHGYPIIIKAAAGGGGRGMRVATDKK
HHHHHHHHHHCCCEECCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEECCHH
ELLEGLQSASSEAKAAFGDPSVFLERYLKNPKHIEVQVLGDAYGNLVHFYERDCSIQRRH
HHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHH
QKVVEFAPSLALPGATRLALCTDALKIANQVGYRNAGTVEFLLDEDGKYYFIEMNPRIQV
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEE
EHTVTEMITGRNLVQAQILIAEGKRLSDPEINIPNQGSIEMRGYAIQCRITTEDPGNNFA
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCC
PDFGTLSTYRSSAGCGVRLDAGNAFTGAQITPHYDSLLVKVSAWGLTFAEAAHIMDRSLQ
CCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHEEEEEECCCCHHHHHHHHHHHHHH
EFRVRGVKTNIGFLENVITHPVFLAGGCNTSFIDQHPELLVIPEKKDRANKVLQFLGDVI
HHHHCCCCCCHHHHHHHHHCCEEEECCCCCCHHCCCCCEEEECCCCHHHHHHHHHHHHHE
VNGSPGVAKPLRSAELIEATVPQIAPFAQRPKGTRDILREKGAEGLSKWVMEQNHLLLTD
ECCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCHHHHHHHHHCCCCEEEEE
TTMRDAHQSLLATRVRTHDLLKIAEPTSHLASDLFSLELWGGATFDVTMRFLKEDPWQRL
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCHHHHHHHHHCCHHHHH
HALSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVAQAAESGVDVFRVFDSLNWTRGMQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
VAMEAVQKSGKICEAAICYTGDISDPTRTKYPLSYYVSMAKELEKMGAHILAIKDMAGLL
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPYAGYQLVKALKEEIGIPVHLHTHDTSGNGGALLVMAAQAGVDIVDAALSSISGLTSQP
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
NLNALVATLKGTELDPKVNEHGLQQLANYWETVRDFYAPFESGLKSGTAEVYHHEIPGGQ
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCC
YSNYKPQVAGLGLLERWEECKEMYHKVNVLFGDVVKVTPSSKVVGDMAMFLVKNNLEPAD
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCC
VFVPGADLAFPESVVGFFKGMIGQPYQGFPEELQKIVLKGQEPITCRPGELLEPTDFEKE
EEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHH
RATAEAKAGHPVNDEELMSYIMYPSVYVEYAKHRQEYSDVSVIPTPVFFYGLEPGQETSI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCEE
ELQPGKTLIVKLNAVGKTQPDGTKQIYFELNGNSRSVTVRDQSVQSDDCGHEKADKSNPK
EECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCC
HVGVPMPGKVIKMNVKTGDSVKAGDILAVTEAMKMETNIKAKEDGTVFEVRCKEGGKVEK
EECCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
EELLIVMA
CCEEEEEC
>Mature Secondary Structure
MEARKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKA
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEEEECCCC
PIDAYLGIDEIIALAKKREVDAIHPGYGFLAENAEFAEKCEANGIAFIGPTAEMQRALGD
CHHHHCCHHHHHHHHHHCCCCEECCCCCEEECCCHHHHHHCCCCEEEECCHHHHHHHHHH
KVAARKVAKAAGVTTVPGTEEPITHEEDALIFAKNHGYPIIIKAAAGGGGRGMRVATDKK
HHHHHHHHHHCCCEECCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEECCHH
ELLEGLQSASSEAKAAFGDPSVFLERYLKNPKHIEVQVLGDAYGNLVHFYERDCSIQRRH
HHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHH
QKVVEFAPSLALPGATRLALCTDALKIANQVGYRNAGTVEFLLDEDGKYYFIEMNPRIQV
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEE
EHTVTEMITGRNLVQAQILIAEGKRLSDPEINIPNQGSIEMRGYAIQCRITTEDPGNNFA
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCC
PDFGTLSTYRSSAGCGVRLDAGNAFTGAQITPHYDSLLVKVSAWGLTFAEAAHIMDRSLQ
CCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHEEEEEECCCCHHHHHHHHHHHHHH
EFRVRGVKTNIGFLENVITHPVFLAGGCNTSFIDQHPELLVIPEKKDRANKVLQFLGDVI
HHHHCCCCCCHHHHHHHHHCCEEEECCCCCCHHCCCCCEEEECCCCHHHHHHHHHHHHHE
VNGSPGVAKPLRSAELIEATVPQIAPFAQRPKGTRDILREKGAEGLSKWVMEQNHLLLTD
ECCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCHHHHHHHHHCCCCEEEEE
TTMRDAHQSLLATRVRTHDLLKIAEPTSHLASDLFSLELWGGATFDVTMRFLKEDPWQRL
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCHHHHHHHHHCCHHHHH
HALSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVAQAAESGVDVFRVFDSLNWTRGMQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
VAMEAVQKSGKICEAAICYTGDISDPTRTKYPLSYYVSMAKELEKMGAHILAIKDMAGLL
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPYAGYQLVKALKEEIGIPVHLHTHDTSGNGGALLVMAAQAGVDIVDAALSSISGLTSQP
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
NLNALVATLKGTELDPKVNEHGLQQLANYWETVRDFYAPFESGLKSGTAEVYHHEIPGGQ
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCC
YSNYKPQVAGLGLLERWEECKEMYHKVNVLFGDVVKVTPSSKVVGDMAMFLVKNNLEPAD
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCC
VFVPGADLAFPESVVGFFKGMIGQPYQGFPEELQKIVLKGQEPITCRPGELLEPTDFEKE
EEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHH
RATAEAKAGHPVNDEELMSYIMYPSVYVEYAKHRQEYSDVSVIPTPVFFYGLEPGQETSI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCEE
ELQPGKTLIVKLNAVGKTQPDGTKQIYFELNGNSRSVTVRDQSVQSDDCGHEKADKSNPK
EECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCC
HVGVPMPGKVIKMNVKTGDSVKAGDILAVTEAMKMETNIKAKEDGTVFEVRCKEGGKVEK
EECCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
EELLIVMA
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]