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The map label for this gene is yhdH [H]

Identifier: 197116581

GI number: 197116581

Start: 212221

End: 213225

Strand: Reverse

Name: yhdH [H]

Synonym: Gbem_0181

Alternate gene names: 197116581

Gene position: 213225-212221 (Counterclockwise)

Preceding gene: 197116582

Following gene: 197116580

Centisome position: 4.62

GC content: 65.67

Gene sequence:

>1005_bases
ATGGCAGCGGAACGTTTCGATGCACTAGTGGTAGAGGAAGAGGCGCCCGGAAGCTTCACCCGCCGGATCAAGAGCAGATC
GATCGACGAACTGCCGCCGGGCGAGCTGCTGGTCAAGGTCCGTTACTCCTCGCTCAACTACAAGGACGCGCTCTCCGCGC
TGGGACGCCCCGGGGTGACCAAGAACTATCCCCATACCCCTGGCATCGACGCGGCGGGCGAGGTGGTCTCCTGTTCCGAC
GGCGCCTTCAAAAGCGGCGAAAAGGTGATCGTGACCGGCTACGACTTGGGCATGAATACCCCCGGGGGATACGGCCAATA
CATCCGAGTCCCCTCCGCCTGGGGGGTCCGTCTCCCCGAGGGGCTGTCGCTGAAGGAGAGCATGGCCATCGGCACCGCGG
GGCTGACCGCGGGGCTGTCGCTGCAAAAGCTCGTCCAGGCTGGGGTCAGGCCGGAACACGGAGAGATCCTGGTGACCGGC
GCCACCGGCGGGGTCGGCAGCGTCGCCGTAACGCTTCTCGCCCAGGCGGGGTACCAGGTCGTGGCTGTCACCGGGAAGGC
CCGGGAGACCGAGTTCCTCACAGGGCTTGGGGCGCGCCAGGTATTGAACCGTGACGCCTTCCTGCAGAACTCCGACCGCC
CGCTCCTGAAGGAACGCTGGGCTGGGGTCATCGATGTCGTGGGCGGTCCCATGCTGGCGGCAGCCATAAAATCCACCGGG
TACGGCGGCGTGGTCACCTGCTGCGGGCTTGCCGGTTCCGCCGAGCTCCCCCTGAACGTCTTCCCGTTCATTCTACGGGG
GGTGTCGCTCTTGGGCGTCGACTCCGCGCAGGCCCCTTCCACCGTCAGAAACGAGGTATGGCAGCGGCTGGCAGGAGATT
GGAAGCCGCAGCGGATTCTCGAGCAGGTGCAGGAAGTGCCGCTGGCCCAGCTGGAACAGAAGTTCGACGCCATTTTGAAA
GGTGAGTTGCGCGGCCGGACGGTAGTCAATCTCGCCCCCCGTTAG

Upstream 100 bases:

>100_bases
CAGGAGCTGATCGGCAAGAGCGCCGGCGACGAGGCCCGGATTGGGAGAGTGGCATACGAGATTGTCGCAGTATCCTGACC
CGGAACCAACAGGAGGGAAC

Downstream 100 bases:

>100_bases
CAAAGATCTTCCCCTGCCATGGTCAGCCTGTCTCCCCTCGCCCTTTGGGAGAGGGGCGGGGGTGAGGGCAGTGCCCAGCC
AGGATCCCGCCTTCGTGACG

Product: zinc-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAAERFDALVVEEEAPGSFTRRIKSRSIDELPPGELLVKVRYSSLNYKDALSALGRPGVTKNYPHTPGIDAAGEVVSCSD
GAFKSGEKVIVTGYDLGMNTPGGYGQYIRVPSAWGVRLPEGLSLKESMAIGTAGLTAGLSLQKLVQAGVRPEHGEILVTG
ATGGVGSVAVTLLAQAGYQVVAVTGKARETEFLTGLGARQVLNRDAFLQNSDRPLLKERWAGVIDVVGGPMLAAAIKSTG
YGGVVTCCGLAGSAELPLNVFPFILRGVSLLGVDSAQAPSTVRNEVWQRLAGDWKPQRILEQVQEVPLAQLEQKFDAILK
GELRGRTVVNLAPR

Sequences:

>Translated_334_residues
MAAERFDALVVEEEAPGSFTRRIKSRSIDELPPGELLVKVRYSSLNYKDALSALGRPGVTKNYPHTPGIDAAGEVVSCSD
GAFKSGEKVIVTGYDLGMNTPGGYGQYIRVPSAWGVRLPEGLSLKESMAIGTAGLTAGLSLQKLVQAGVRPEHGEILVTG
ATGGVGSVAVTLLAQAGYQVVAVTGKARETEFLTGLGARQVLNRDAFLQNSDRPLLKERWAGVIDVVGGPMLAAAIKSTG
YGGVVTCCGLAGSAELPLNVFPFILRGVSLLGVDSAQAPSTVRNEVWQRLAGDWKPQRILEQVQEVPLAQLEQKFDAILK
GELRGRTVVNLAPR
>Mature_333_residues
AAERFDALVVEEEAPGSFTRRIKSRSIDELPPGELLVKVRYSSLNYKDALSALGRPGVTKNYPHTPGIDAAGEVVSCSDG
AFKSGEKVIVTGYDLGMNTPGGYGQYIRVPSAWGVRLPEGLSLKESMAIGTAGLTAGLSLQKLVQAGVRPEHGEILVTGA
TGGVGSVAVTLLAQAGYQVVAVTGKARETEFLTGLGARQVLNRDAFLQNSDRPLLKERWAGVIDVVGGPMLAAAIKSTGY
GGVVTCCGLAGSAELPLNVFPFILRGVSLLGVDSAQAPSTVRNEVWQRLAGDWKPQRILEQVQEVPLAQLEQKFDAILKG
ELRGRTVVNLAPR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI28557745, Length=234, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789651, Length=326, Percent_Identity=44.478527607362, Blast_Score=271, Evalue=6e-74,
Organism=Saccharomyces cerevisiae, GI6323961, Length=329, Percent_Identity=25.8358662613982, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=338, Percent_Identity=23.6686390532544, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35320; Mature: 35189

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAERFDALVVEEEAPGSFTRRIKSRSIDELPPGELLVKVRYSSLNYKDALSALGRPGVT
CCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
KNYPHTPGIDAAGEVVSCSDGAFKSGEKVIVTGYDLGMNTPGGYGQYIRVPSAWGVRLPE
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCC
GLSLKESMAIGTAGLTAGLSLQKLVQAGVRPEHGEILVTGATGGVGSVAVTLLAQAGYQV
CCCHHHHHHHCCHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEE
VAVTGKARETEFLTGLGARQVLNRDAFLQNSDRPLLKERWAGVIDVVGGPMLAAAIKSTG
EEEECCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHCCCHHHHHHHHCCC
YGGVVTCCGLAGSAELPLNVFPFILRGVSLLGVDSAQAPSTVRNEVWQRLAGDWKPQRIL
CCCHHHECCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
EQVQEVPLAQLEQKFDAILKGELRGRTVVNLAPR
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure 
AAERFDALVVEEEAPGSFTRRIKSRSIDELPPGELLVKVRYSSLNYKDALSALGRPGVT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
KNYPHTPGIDAAGEVVSCSDGAFKSGEKVIVTGYDLGMNTPGGYGQYIRVPSAWGVRLPE
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCC
GLSLKESMAIGTAGLTAGLSLQKLVQAGVRPEHGEILVTGATGGVGSVAVTLLAQAGYQV
CCCHHHHHHHCCHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEE
VAVTGKARETEFLTGLGARQVLNRDAFLQNSDRPLLKERWAGVIDVVGGPMLAAAIKSTG
EEEECCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHCCCHHHHHHHHCCC
YGGVVTCCGLAGSAELPLNVFPFILRGVSLLGVDSAQAPSTVRNEVWQRLAGDWKPQRIL
CCCHHHECCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
EQVQEVPLAQLEQKFDAILKGELRGRTVVNLAPR
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]