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The map label for this gene is nuoA-2

Identifier: 197116579

GI number: 197116579

Start: 210128

End: 210532

Strand: Reverse

Name: nuoA-2

Synonym: Gbem_0179

Alternate gene names: 197116579

Gene position: 210532-210128 (Counterclockwise)

Preceding gene: 197116580

Following gene: 197116578

Centisome position: 4.56

GC content: 58.02

Gene sequence:

>405_bases
ATGCCCGTTACCGCACAGCAAGTAGAATTAATTCCCCTTGCCATCTACACCCTCTTCGCGGTGGGGCTCATCGGCATCCT
CTTGCTGGCGGCGCGCTACCTCGGTTCAGGGAAGGAAACCTCCGAAAAGCACATACCCTTCGAATCGGGGATGGTTCCCA
CCGGCAATGCCCGGCATGCATCCCAAGTCCCCTTCTACCTGATCGCTATCTTCTTCATAGTCTTCGACGTGGAAGGGGCC
TTCATACTTGCCTGGGCCACCTCCTGGGACCTCCTTGGCATTCCAGGGCTGGTCCACATCACCCTCTTCATCACGGTGCT
CCTTTTAGGGCTGGTCTGGCTCTGGATGAAAGGTGGGCTCGACTGGGGTCCTTCAGCCATGCGCGCGCGGGGTAAACGAT
CTTGA

Upstream 100 bases:

>100_bases
AACGACTAAAATAAGCGCCGTTCCAAATTGACTTTCATCGGCTCTACGTTAGATTATACGGGTTGCAGAAACCCCCTATC
TTCTCATTGAAAGGCCAATG

Downstream 100 bases:

>100_bases
GCCAGGGTGACGACGACAAAATACCCGAAAACGTACTGCTCGCCTCCCTGGACGACATGATCAACTGGGGGAGGGCGAAT
TCTCTATGGCCGATGTTCTT

Product: NADH dehydrogenase I subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MPVTAQQVELIPLAIYTLFAVGLIGILLLAARYLGSGKETSEKHIPFESGMVPTGNARHASQVPFYLIAIFFIVFDVEGA
FILAWATSWDLLGIPGLVHITLFITVLLLGLVWLWMKGGLDWGPSAMRARGKRS

Sequences:

>Translated_134_residues
MPVTAQQVELIPLAIYTLFAVGLIGILLLAARYLGSGKETSEKHIPFESGMVPTGNARHASQVPFYLIAIFFIVFDVEGA
FILAWATSWDLLGIPGLVHITLFITVLLLGLVWLWMKGGLDWGPSAMRARGKRS
>Mature_133_residues
PVTAQQVELIPLAIYTLFAVGLIGILLLAARYLGSGKETSEKHIPFESGMVPTGNARHASQVPFYLIAIFFIVFDVEGAF
ILAWATSWDLLGIPGLVHITLFITVLLLGLVWLWMKGGLDWGPSAMRARGKRS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=122, Percent_Identity=41.8032786885246, Blast_Score=96, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA1_GEOBB (B5E973)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137006.1
- GeneID:   6783001
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0179
- HOGENOM:   HBG605540
- OMA:   DSTGSAR
- ProtClustDB:   CLSK829284
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 14668; Mature: 14536

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x26380c6c)-; HASH(0x248ad328)-; HASH(0x26594a18)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTAQQVELIPLAIYTLFAVGLIGILLLAARYLGSGKETSEKHIPFESGMVPTGNARHA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
SQVPFYLIAIFFIVFDVEGAFILAWATSWDLLGIPGLVHITLFITVLLLGLVWLWMKGGL
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DWGPSAMRARGKRS
CCCCHHHHHCCCCH
>Mature Secondary Structure 
PVTAQQVELIPLAIYTLFAVGLIGILLLAARYLGSGKETSEKHIPFESGMVPTGNARHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
SQVPFYLIAIFFIVFDVEGAFILAWATSWDLLGIPGLVHITLFITVLLLGLVWLWMKGGL
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DWGPSAMRARGKRS
CCCCHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA