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The map label for this gene is ligD

Identifier: 197116528

GI number: 197116528

Start: 152612

End: 155227

Strand: Reverse

Name: ligD

Synonym: Gbem_0128

Alternate gene names: NA

Gene position: 155227-152612 (Counterclockwise)

Preceding gene: 197116537

Following gene: 197116527

Centisome position: 3.36

GC content: 62.73

Gene sequence:

>2616_bases
ATGGGACTGGAAGAGTATCAGCGCAAAAGGAATCCGGGGAGGACGCCGGAGCCGCCGGCCAGCGAGGGGAAGTCGGAGAG
ATCTTTACGGTTCGTGGTGCATAAGCACGCGGCCTCTCATCTGCATTACGACTTTAGGCTCGAGCTCGACGGAGTTCTGA
AAAGCTGGGCCATCCCCAAGGGCCCCTCGCTGGATCCCTCGGTAAAAAGGCTCGCCATGATGGTGGAGGACCACCCCTAC
GACTACGGCGACTTCGAGGGGGTGATTCCCAAGGGGAATTACGGGGCAGGCGAGGTGATCGTCTGGGACACCGGGAGCTA
TGAGGCCCCGGGGGCGGCCGATCCGGAACAGGGCGTGAGGCTGCTGCGCGAGGGGCTGAAAAAGGGAGACCTGAAATTCA
TCCTCGTCGGCCGGAAATTGAACGGGGAATATGCCCTAGTTCGCATCAAGGGGGACAAGGAGAACACCTGGCTTTTGATC
AAGAAAAACGACCGGTTCGCCTCGACCGAGGACGTGACGTTGCAGGACCGTTCGGTGGTCAGTGACGTCACCATCGAGGA
GCTAAAGACGGGGAGGAAGCCACAGGCGTTGCCCCTAGCCGCCGCAGAGGCGGCGGAACCAGTCGGACCTGTCAGACCTG
CCGCTCCGATGCCGCACCGACTCACTCCGATGCTGGCCAACTCCGCGGCCGAGCCCTTCGACGATCCCGACTGGCTCTTC
GAGATAAAACTCGACGGCTACCGCGCCATCGCCGAGATAGAGGGCGGCGAGGTGCAGCTCTACTCGCGCAACAACCTCTC
CTTCAACAAGCGCTTCCCCGCCATCGTCCAGTCACTTGCTTCCCTGCCGGTCACGGCAGTGCTGGACGGTGAGGTGGTAG
CCCTCGACGCCAAGGGGAGGTCTTCCTTCCAGCTCTTGCAGAACAGCCTGCGCACCGGGGAGAAGAACATCTACTACTAC
GCCTTCGACCTCCTCTACCTCGACGGCGAGGACCTGCGCGCCGAACCGCTCCAGGCACGCAAGGAGAGGCTTCGCAACCT
GCTCCCCGAACTCCCCTGGGTCCGCTTCAGCGACCATATCAGGGAGTACGGCAGGCAGTTCTTCGAGCTTGCCCGCGAGA
ACAACCTGGAGGGAATCCTCGCCAAAAGGGCCGACAGCCGGTATTTTGCGGGAAGAAGAAGCGGCGACTGGCTGAAGATT
AAGATACGGCTGCAGCAGGAGGCGGTGATCTGCGGGTTCACCCAGCCCCGAGGGAGCAGGAAAGGATTGGGCTCTCTCGT
GCTGGGGGTCTACGAAAATGGCGAGCTGGTCTACATCGGGCTTACCGGAGGGGGGTTCGACGATGTGGGGTTGAAGGAGA
TGTACGCTGCGCTGCAACCGCTGATCCAGCCGGAGTCCCCTTTCCGGCAGCAGGTGAAGACCAGCATGCCGGTTACCTGG
ACCAAACCAGTGCTGGTCTGCGAGGTCGAATTCGCCGAGTGGACCGACGAGAACGTCATGCGCCTGCCCATTTTCCTGGG
GCTTCGTGAGGACAAGGACCCCAGGTCCGTGCAGCGGGAGATCTTTCCCGCGGAGGTCCAGCCCCCGGTGCACCATGCGC
AGACGGATCAAGAGGAGGATGTTGGCGAGCCTGCGGCAGGGGAAAAGGTGCCTGCAGAGGAGACGGTTGCCACAGCCAAG
CCTTTCGTGAAGAAGGGGGGCGCGAAGAAAGGGGAGGTAAACCTCGTCATCGACGGGCAGCGGCTCACCCTGACCAACCT
GGACAAGGTCTTCTGGCCGGAGGAGGGATATACCAAGGGGGACGTCATCGACTACTACCGCAAGATGGCACGGGTGATAC
TCCCGTACCTCATGGACCGCCCGGAGTCGATGTACCGTACGCCGCACGGCATCGCCGAAGGAGGTTTCTACCAGAAGGAG
ACGGCCGACCTGATCCCCCCCTGGATCACCGCCCGGGAGATCTATTCCAAACACGTCGACAAGAACATCAAGTTCCTCGT
CTGCCAGGACGAGGCGACGCTCATCTACATGGCCAACCTGGGCTGCATCGAGATCAACCCATGGCTGTCGCGGCTGCAGC
AGCTCGACTACCCCGATTACCTGGTGATCGACCTGGACCCCGAGGACATCTCCTTCGAGAAGGTGATCGAGACCGCGCTC
GCCGTGCACGAAGTCCTGGAAAGCGCGGGCGCGGCCAGTTTCCCGAAGACCTCCGGCGCCACCGGCATCCACATCTACGT
CCCGCTGGGAGCACGCTACGACTACGACACGGCAGGGGTATTCGCGAAGCTGGTGGCGACCCTCGCGCACCACAAGGTCC
CCGGCTTCACCAGCCTCTTGCGCAGCCCCAGGCAGCGCCAGAAAAAGGTGTACCTCGACTTCCTGCAGAACAAGCCGGGC
CAGACCCTCGCCGCCCCCTACAGCATCCGCCCCCGCCCCGGGGCGACCGTTTCGGCGCCGCTTCGCTGGGAGGAAGTGAA
GCCGGGTCTCGACCCGCGCCAGTTCACCATCAACACCATCGGGAAGCGGCTGGAGCAGGTCGGCGACCTGTTCCAAGGCG
TCCTCGGTCCCGGTATCGACATGGAGCGCTGCCTGGAGCGGCTGCAAAACGGGTAG

Upstream 100 bases:

>100_bases
ATAATCTAGCCGCGGTCCTTGCTTTGTCAATTCAGACAAGCCCATCTAAAGCCGATCTGGCGATGTGATAAACTCATGAC
CTTGAAAAGGGGAGGTTCTC

Downstream 100 bases:

>100_bases
CTTTGGCTGAAAACGGGGAGCAGACAGCGCTCATGTGTCCGCGCCCTGCCGCTTTCCAACCTCCAAAAATTGGAAAATTA
CAAGCTGTTAAACCGTTTTC

Product: DNA ligase D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 871; Mature: 870

Protein sequence:

>871_residues
MGLEEYQRKRNPGRTPEPPASEGKSERSLRFVVHKHAASHLHYDFRLELDGVLKSWAIPKGPSLDPSVKRLAMMVEDHPY
DYGDFEGVIPKGNYGAGEVIVWDTGSYEAPGAADPEQGVRLLREGLKKGDLKFILVGRKLNGEYALVRIKGDKENTWLLI
KKNDRFASTEDVTLQDRSVVSDVTIEELKTGRKPQALPLAAAEAAEPVGPVRPAAPMPHRLTPMLANSAAEPFDDPDWLF
EIKLDGYRAIAEIEGGEVQLYSRNNLSFNKRFPAIVQSLASLPVTAVLDGEVVALDAKGRSSFQLLQNSLRTGEKNIYYY
AFDLLYLDGEDLRAEPLQARKERLRNLLPELPWVRFSDHIREYGRQFFELARENNLEGILAKRADSRYFAGRRSGDWLKI
KIRLQQEAVICGFTQPRGSRKGLGSLVLGVYENGELVYIGLTGGGFDDVGLKEMYAALQPLIQPESPFRQQVKTSMPVTW
TKPVLVCEVEFAEWTDENVMRLPIFLGLREDKDPRSVQREIFPAEVQPPVHHAQTDQEEDVGEPAAGEKVPAEETVATAK
PFVKKGGAKKGEVNLVIDGQRLTLTNLDKVFWPEEGYTKGDVIDYYRKMARVILPYLMDRPESMYRTPHGIAEGGFYQKE
TADLIPPWITAREIYSKHVDKNIKFLVCQDEATLIYMANLGCIEINPWLSRLQQLDYPDYLVIDLDPEDISFEKVIETAL
AVHEVLESAGAASFPKTSGATGIHIYVPLGARYDYDTAGVFAKLVATLAHHKVPGFTSLLRSPRQRQKKVYLDFLQNKPG
QTLAAPYSIRPRPGATVSAPLRWEEVKPGLDPRQFTINTIGKRLEQVGDLFQGVLGPGIDMERCLERLQNG

Sequences:

>Translated_871_residues
MGLEEYQRKRNPGRTPEPPASEGKSERSLRFVVHKHAASHLHYDFRLELDGVLKSWAIPKGPSLDPSVKRLAMMVEDHPY
DYGDFEGVIPKGNYGAGEVIVWDTGSYEAPGAADPEQGVRLLREGLKKGDLKFILVGRKLNGEYALVRIKGDKENTWLLI
KKNDRFASTEDVTLQDRSVVSDVTIEELKTGRKPQALPLAAAEAAEPVGPVRPAAPMPHRLTPMLANSAAEPFDDPDWLF
EIKLDGYRAIAEIEGGEVQLYSRNNLSFNKRFPAIVQSLASLPVTAVLDGEVVALDAKGRSSFQLLQNSLRTGEKNIYYY
AFDLLYLDGEDLRAEPLQARKERLRNLLPELPWVRFSDHIREYGRQFFELARENNLEGILAKRADSRYFAGRRSGDWLKI
KIRLQQEAVICGFTQPRGSRKGLGSLVLGVYENGELVYIGLTGGGFDDVGLKEMYAALQPLIQPESPFRQQVKTSMPVTW
TKPVLVCEVEFAEWTDENVMRLPIFLGLREDKDPRSVQREIFPAEVQPPVHHAQTDQEEDVGEPAAGEKVPAEETVATAK
PFVKKGGAKKGEVNLVIDGQRLTLTNLDKVFWPEEGYTKGDVIDYYRKMARVILPYLMDRPESMYRTPHGIAEGGFYQKE
TADLIPPWITAREIYSKHVDKNIKFLVCQDEATLIYMANLGCIEINPWLSRLQQLDYPDYLVIDLDPEDISFEKVIETAL
AVHEVLESAGAASFPKTSGATGIHIYVPLGARYDYDTAGVFAKLVATLAHHKVPGFTSLLRSPRQRQKKVYLDFLQNKPG
QTLAAPYSIRPRPGATVSAPLRWEEVKPGLDPRQFTINTIGKRLEQVGDLFQGVLGPGIDMERCLERLQNG
>Mature_870_residues
GLEEYQRKRNPGRTPEPPASEGKSERSLRFVVHKHAASHLHYDFRLELDGVLKSWAIPKGPSLDPSVKRLAMMVEDHPYD
YGDFEGVIPKGNYGAGEVIVWDTGSYEAPGAADPEQGVRLLREGLKKGDLKFILVGRKLNGEYALVRIKGDKENTWLLIK
KNDRFASTEDVTLQDRSVVSDVTIEELKTGRKPQALPLAAAEAAEPVGPVRPAAPMPHRLTPMLANSAAEPFDDPDWLFE
IKLDGYRAIAEIEGGEVQLYSRNNLSFNKRFPAIVQSLASLPVTAVLDGEVVALDAKGRSSFQLLQNSLRTGEKNIYYYA
FDLLYLDGEDLRAEPLQARKERLRNLLPELPWVRFSDHIREYGRQFFELARENNLEGILAKRADSRYFAGRRSGDWLKIK
IRLQQEAVICGFTQPRGSRKGLGSLVLGVYENGELVYIGLTGGGFDDVGLKEMYAALQPLIQPESPFRQQVKTSMPVTWT
KPVLVCEVEFAEWTDENVMRLPIFLGLREDKDPRSVQREIFPAEVQPPVHHAQTDQEEDVGEPAAGEKVPAEETVATAKP
FVKKGGAKKGEVNLVIDGQRLTLTNLDKVFWPEEGYTKGDVIDYYRKMARVILPYLMDRPESMYRTPHGIAEGGFYQKET
ADLIPPWITAREIYSKHVDKNIKFLVCQDEATLIYMANLGCIEINPWLSRLQQLDYPDYLVIDLDPEDISFEKVIETALA
VHEVLESAGAASFPKTSGATGIHIYVPLGARYDYDTAGVFAKLVATLAHHKVPGFTSLLRSPRQRQKKVYLDFLQNKPGQ
TLAAPYSIRPRPGATVSAPLRWEEVKPGLDPRQFTINTIGKRLEQVGDLFQGVLGPGIDMERCLERLQNG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=373, Percent_Identity=29.4906166219839, Blast_Score=116, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71985269, Length=346, Percent_Identity=30.3468208092486, Blast_Score=102, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320038, Length=354, Percent_Identity=27.683615819209, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324578, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762424, Length=357, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 97721; Mature: 97589

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLEEYQRKRNPGRTPEPPASEGKSERSLRFVVHKHAASHLHYDFRLELDGVLKSWAIPK
CCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEHHHHHHHCCCCC
GPSLDPSVKRLAMMVEDHPYDYGDFEGVIPKGNYGAGEVIVWDTGSYEAPGAADPEQGVR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
LLREGLKKGDLKFILVGRKLNGEYALVRIKGDKENTWLLIKKNDRFASTEDVTLQDRSVV
HHHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEECCCHHH
SDVTIEELKTGRKPQALPLAAAEAAEPVGPVRPAAPMPHRLTPMLANSAAEPFDDPDWLF
HHCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEE
EIKLDGYRAIAEIEGGEVQLYSRNNLSFNKRFPAIVQSLASLPVTAVLDGEVVALDAKGR
EEEECCEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEECCCEEEEECCCC
SSFQLLQNSLRTGEKNIYYYAFDLLYLDGEDLRAEPLQARKERLRNLLPELPWVRFSDHI
HHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
REYGRQFFELARENNLEGILAKRADSRYFAGRRSGDWLKIKIRLQQEAVICGFTQPRGSR
HHHHHHHHHHHHHCCCCEEEHHCCCCCEECCCCCCCEEEEEEEEECCEEEEECCCCCCCC
KGLGSLVLGVYENGELVYIGLTGGGFDDVGLKEMYAALQPLIQPESPFRQQVKTSMPVTW
CCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEE
TKPVLVCEVEFAEWTDENVMRLPIFLGLREDKDPRSVQREIFPAEVQPPVHHAQTDQEED
CCCEEEEEEEHHCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHH
VGEPAAGEKVPAEETVATAKPFVKKGGAKKGEVNLVIDGQRLTLTNLDKVFWPEEGYTKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCHHHCCCCCCCCCC
DVIDYYRKMARVILPYLMDRPESMYRTPHGIAEGGFYQKETADLIPPWITAREIYSKHVD
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCC
KNIKFLVCQDEATLIYMANLGCIEINPWLSRLQQLDYPDYLVIDLDPEDISFEKVIETAL
CCCEEEEEECCCEEEEEECCCEEEECHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
AVHEVLESAGAASFPKTSGATGIHIYVPLGARYDYDTAGVFAKLVATLAHHKVPGFTSLL
HHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
RSPRQRQKKVYLDFLQNKPGQTLAAPYSIRPRPGATVSAPLRWEEVKPGLDPRQFTINTI
HCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCCCHHHCCCCCCCCEEEHHHH
GKRLEQVGDLFQGVLGPGIDMERCLERLQNG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
GLEEYQRKRNPGRTPEPPASEGKSERSLRFVVHKHAASHLHYDFRLELDGVLKSWAIPK
CHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEHHHHHHHCCCCC
GPSLDPSVKRLAMMVEDHPYDYGDFEGVIPKGNYGAGEVIVWDTGSYEAPGAADPEQGVR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
LLREGLKKGDLKFILVGRKLNGEYALVRIKGDKENTWLLIKKNDRFASTEDVTLQDRSVV
HHHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEECCCHHH
SDVTIEELKTGRKPQALPLAAAEAAEPVGPVRPAAPMPHRLTPMLANSAAEPFDDPDWLF
HHCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEE
EIKLDGYRAIAEIEGGEVQLYSRNNLSFNKRFPAIVQSLASLPVTAVLDGEVVALDAKGR
EEEECCEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEECCCEEEEECCCC
SSFQLLQNSLRTGEKNIYYYAFDLLYLDGEDLRAEPLQARKERLRNLLPELPWVRFSDHI
HHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
REYGRQFFELARENNLEGILAKRADSRYFAGRRSGDWLKIKIRLQQEAVICGFTQPRGSR
HHHHHHHHHHHHHCCCCEEEHHCCCCCEECCCCCCCEEEEEEEEECCEEEEECCCCCCCC
KGLGSLVLGVYENGELVYIGLTGGGFDDVGLKEMYAALQPLIQPESPFRQQVKTSMPVTW
CCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEE
TKPVLVCEVEFAEWTDENVMRLPIFLGLREDKDPRSVQREIFPAEVQPPVHHAQTDQEED
CCCEEEEEEEHHCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHH
VGEPAAGEKVPAEETVATAKPFVKKGGAKKGEVNLVIDGQRLTLTNLDKVFWPEEGYTKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCHHHCCCCCCCCCC
DVIDYYRKMARVILPYLMDRPESMYRTPHGIAEGGFYQKETADLIPPWITAREIYSKHVD
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCC
KNIKFLVCQDEATLIYMANLGCIEINPWLSRLQQLDYPDYLVIDLDPEDISFEKVIETAL
CCCEEEEEECCCEEEEEECCCEEEECHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
AVHEVLESAGAASFPKTSGATGIHIYVPLGARYDYDTAGVFAKLVATLAHHKVPGFTSLL
HHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
RSPRQRQKKVYLDFLQNKPGQTLAAPYSIRPRPGATVSAPLRWEEVKPGLDPRQFTINTI
HCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCCCHHHCCCCCCCCEEEHHHH
GKRLEQVGDLFQGVLGPGIDMERCLERLQNG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]