| Definition | Geobacter bemidjiensis Bem chromosome, complete genome. |
|---|---|
| Accession | NC_011146 |
| Length | 4,615,150 |
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The map label for this gene is gyrA [H]
Identifier: 197116407
GI number: 197116407
Start: 6866
End: 9376
Strand: Direct
Name: gyrA [H]
Synonym: Gbem_0005
Alternate gene names: 197116407
Gene position: 6866-9376 (Clockwise)
Preceding gene: 197116406
Following gene: 308535144
Centisome position: 0.15
GC content: 60.81
Gene sequence:
>2511_bases ATGCTGAATCAACTCAACAAGGTATCGGTAAACATCGAAGACGAGATGAAACGCTCCTACATGGACTACGCCATGTCCGT GATCGTGGGGCGCGCTCTTCCGGACGTGCGCGACGGACTGAAGCCGGTACACAGGCGCTGCCTGTTCGCCATGTACGACA TGAGCAACGACTGGAACAAGCCGTACAAGAAATCGGCCCGCGTGGTCGGCGACGTCATCGGTAAGTACCACCCGCACGGC GACACCGCCGTGTACGACACCCTGGTCAGGATGGCCCAGGACTTCTCGCTGCGCTACCCGCTGGTCGACGGCCAGGGGAA CTTCGGCTCCATCGACGGCGACTCCCCTGCGGCTATGCGTTACACCGAGATCAGGATGGAGCAGCTGGCCCACGAGCTTT TGGCCGACATCGACAAGGAAACGGTCCCCTACGGCCCCAACTACGACGACTCGCTGAAAGAACCGCTGGTACTCCCCTCC AAGTTCCCGAACCTCTTGGTGAACGGCTCCGCCGGCATCGCGGTCGGCATGGCCACCAACATCCCGCCGCACAACCTCTC CGAAGTGATCGACGGCATCGTGGCCATCATCGATAACCCGCAGCTTACCTTCGAGGAGCTGGTGGAACTGATCCCGGGTC CGGATTTTCCGACCGGCGGCTTCATCTACGGCCGCGAAGGGATCATGAAGGCCTACTCGACCGGCCGCGGCATCATCCAG ATGCGCGCCAAGGTGCAGATCGAGACCCAGAAAAAGACCGAGCGCCAGTCCATCGTGGTCACGGAAATCCCGTACCAGGT GAACAAGGCGAGGCTGGTCGAGAAGATAGCCGAGCTGGTCAAGGAGAAGAAGATCGAGGGGATCTCGGACTTAAGGGACG AGAGCGACCGCGAGGGTATGCGCGTCGTCATCGAACTGAAGAAGGACGAAAACCCGACCATCATCCTGAACCACCTCTAC AAGCAGACCCAGATGCAGTCCTCCTTCGGCATCATCATGCTGGCCATCGTCAACAGCCGGCCGCGCGTTTTGACGCTCAG GGAGACCATCGACTTCTTCATCGAGCACAGAAAGGAGATCGTCACCCGCCGCACCATCTTCGACCTGAAGAAGGCAGAGG CGAGGGCCCATATCCTGGAAGGCTTGAAGATAGCGCTGGACAACCTGGACGAGGTGATCGCGCTGATCAAGGCGAGCGCC TCCCCGGCCGAGGCGAAGGCGGGGCTCATGGAGCGCTTCGGGCTCTCCGACCTTCAGGCCCAGGCGATCCTCGACATGAG GCTGCACCGCTTAACCGGCCTCGAGCGCGAGAAGATCATGGAGGAACTGCGCGAGATTCTGAAGTACATCGCCAGGTTGA AAGAGATCCTCGCCTCCGAGGCGGAGATCCTCAAGATCATCGTCGGGGAACTGGTCGAGCTCAAAGACAAGTTCGGCGAC AAGCGCCGCTCCGAAATAGTGATGCAGACTGCGGACATCTCCTTGGAGGACACCATCGTCGAGGAAGACATGGTGGTCAC CATCTCGCACACGGGCTACATCAAGCGCAACGCCGTCACCCTCTACCGCGCCCAGCGCCGCGGCGGCAAGGGCAAGACCG GCATGAAGACCAAGGAAGAGGATTTCGTCGAGCAGCTTTTCATCGCCTCCACCAAGGATTATCTGATGTTCTTCACCGAT GCCGGGAAGGTCTACTGGCTCAAGGTGTACGAGATCCCGGAGGCGGGGCGCGCGGCGCGCGGCAAGGCGATCGTGAACCT CTTGAACCTGGCGGCGAACGAGAAGATCACCACCATACTCCCGGTCAAGGAGTTCGTGGACGACAAGTTCATCATGATGG CGACCAGAAACGGCGTGGTGAAGAAGACCAACATGATGGAGTACTCGCACCCGAGGGTAGGCGGCATCATCGCCGTGAAC CTCGACGAAGGGGACAAGCTGATCACCGTGGCGCTCACCGACGGCAAGCAGGACGTGCTGCTCGCCTCCGCCAACGGCAA GGCGATCCGCTTCAAGGAAGAGGACGTCCGCACCGTGGGACGCGTCTCGCGCGGGGTGCGCGGCATGACGCTGGAGGGCG AGGACGTGGTGATCGGCATGGAGATCCTCAACGAGAACTTCACCGACTCCACCATCTTCACCGTGACCGAGAACGGCTAT GGCAAGCGGACCGAGATCAGCGAGTACCGCAGCCAGTCGCGCGGCGGCAAGGGGGTCATCACCATCAAGACCACCGAGAG AAACGGCAACGTGGTCGACATCAAGCAGGTCAACGACGATAACGACCTGATGCTCATCACGGACCAGGGAAAGATCCTGC GCGTTCCCGTCGCCGGCTTCTCCATCATCGGGCGCAACACCCAGGGGGTGCGCCTCATGGTGAAAGAGGAGAACGAGAGG GTGGTCGCCGTGGCCCGGCTCGCCGAGAAAGAGGAGCAGGACGAGTCGGAAGACGGCGAACTCGACGAGATGGTGGAACT GGAATCGGGCGAGGAGCAGGGCGAAGAATAA
Upstream 100 bases:
>100_bases AATCTACCCTCCCTTCGGGAGGGGATAGTCTTTTGCATATTTCTACTGCGACGCAAAAGCTTCGGCGAGTACGCCGCCTT TTGACGGAAAGGTTCCTTAA
Downstream 100 bases:
>100_bases AGTGAGGGGCGGCCCCTCTGGGGCCGCTATGCAGCAATAGCAGCAAAGAGCGGTGCAGCAGATAGAGTCGGACCTTGTTA TGTTCCCCGTTTGGGGGTGC
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 836; Mature: 836
Protein sequence:
>836_residues MLNQLNKVSVNIEDEMKRSYMDYAMSVIVGRALPDVRDGLKPVHRRCLFAMYDMSNDWNKPYKKSARVVGDVIGKYHPHG DTAVYDTLVRMAQDFSLRYPLVDGQGNFGSIDGDSPAAMRYTEIRMEQLAHELLADIDKETVPYGPNYDDSLKEPLVLPS KFPNLLVNGSAGIAVGMATNIPPHNLSEVIDGIVAIIDNPQLTFEELVELIPGPDFPTGGFIYGREGIMKAYSTGRGIIQ MRAKVQIETQKKTERQSIVVTEIPYQVNKARLVEKIAELVKEKKIEGISDLRDESDREGMRVVIELKKDENPTIILNHLY KQTQMQSSFGIIMLAIVNSRPRVLTLRETIDFFIEHRKEIVTRRTIFDLKKAEARAHILEGLKIALDNLDEVIALIKASA SPAEAKAGLMERFGLSDLQAQAILDMRLHRLTGLEREKIMEELREILKYIARLKEILASEAEILKIIVGELVELKDKFGD KRRSEIVMQTADISLEDTIVEEDMVVTISHTGYIKRNAVTLYRAQRRGGKGKTGMKTKEEDFVEQLFIASTKDYLMFFTD AGKVYWLKVYEIPEAGRAARGKAIVNLLNLAANEKITTILPVKEFVDDKFIMMATRNGVVKKTNMMEYSHPRVGGIIAVN LDEGDKLITVALTDGKQDVLLASANGKAIRFKEEDVRTVGRVSRGVRGMTLEGEDVVIGMEILNENFTDSTIFTVTENGY GKRTEISEYRSQSRGGKGVITIKTTERNGNVVDIKQVNDDNDLMLITDQGKILRVPVAGFSIIGRNTQGVRLMVKEENER VVAVARLAEKEEQDESEDGELDEMVELESGEEQGEE
Sequences:
>Translated_836_residues MLNQLNKVSVNIEDEMKRSYMDYAMSVIVGRALPDVRDGLKPVHRRCLFAMYDMSNDWNKPYKKSARVVGDVIGKYHPHG DTAVYDTLVRMAQDFSLRYPLVDGQGNFGSIDGDSPAAMRYTEIRMEQLAHELLADIDKETVPYGPNYDDSLKEPLVLPS KFPNLLVNGSAGIAVGMATNIPPHNLSEVIDGIVAIIDNPQLTFEELVELIPGPDFPTGGFIYGREGIMKAYSTGRGIIQ MRAKVQIETQKKTERQSIVVTEIPYQVNKARLVEKIAELVKEKKIEGISDLRDESDREGMRVVIELKKDENPTIILNHLY KQTQMQSSFGIIMLAIVNSRPRVLTLRETIDFFIEHRKEIVTRRTIFDLKKAEARAHILEGLKIALDNLDEVIALIKASA SPAEAKAGLMERFGLSDLQAQAILDMRLHRLTGLEREKIMEELREILKYIARLKEILASEAEILKIIVGELVELKDKFGD KRRSEIVMQTADISLEDTIVEEDMVVTISHTGYIKRNAVTLYRAQRRGGKGKTGMKTKEEDFVEQLFIASTKDYLMFFTD AGKVYWLKVYEIPEAGRAARGKAIVNLLNLAANEKITTILPVKEFVDDKFIMMATRNGVVKKTNMMEYSHPRVGGIIAVN LDEGDKLITVALTDGKQDVLLASANGKAIRFKEEDVRTVGRVSRGVRGMTLEGEDVVIGMEILNENFTDSTIFTVTENGY GKRTEISEYRSQSRGGKGVITIKTTERNGNVVDIKQVNDDNDLMLITDQGKILRVPVAGFSIIGRNTQGVRLMVKEENER VVAVARLAEKEEQDESEDGELDEMVELESGEEQGEE >Mature_836_residues MLNQLNKVSVNIEDEMKRSYMDYAMSVIVGRALPDVRDGLKPVHRRCLFAMYDMSNDWNKPYKKSARVVGDVIGKYHPHG DTAVYDTLVRMAQDFSLRYPLVDGQGNFGSIDGDSPAAMRYTEIRMEQLAHELLADIDKETVPYGPNYDDSLKEPLVLPS KFPNLLVNGSAGIAVGMATNIPPHNLSEVIDGIVAIIDNPQLTFEELVELIPGPDFPTGGFIYGREGIMKAYSTGRGIIQ MRAKVQIETQKKTERQSIVVTEIPYQVNKARLVEKIAELVKEKKIEGISDLRDESDREGMRVVIELKKDENPTIILNHLY KQTQMQSSFGIIMLAIVNSRPRVLTLRETIDFFIEHRKEIVTRRTIFDLKKAEARAHILEGLKIALDNLDEVIALIKASA SPAEAKAGLMERFGLSDLQAQAILDMRLHRLTGLEREKIMEELREILKYIARLKEILASEAEILKIIVGELVELKDKFGD KRRSEIVMQTADISLEDTIVEEDMVVTISHTGYIKRNAVTLYRAQRRGGKGKTGMKTKEEDFVEQLFIASTKDYLMFFTD AGKVYWLKVYEIPEAGRAARGKAIVNLLNLAANEKITTILPVKEFVDDKFIMMATRNGVVKKTNMMEYSHPRVGGIIAVN LDEGDKLITVALTDGKQDVLLASANGKAIRFKEEDVRTVGRVSRGVRGMTLEGEDVVIGMEILNENFTDSTIFTVTENGY GKRTEISEYRSQSRGGKGVITIKTTERNGNVVDIKQVNDDNDLMLITDQGKILRVPVAGFSIIGRNTQGVRLMVKEENER VVAVARLAEKEEQDESEDGELDEMVELESGEEQGEE
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=313, Percent_Identity=24.9201277955272, Blast_Score=76, Evalue=2e-13, Organism=Homo sapiens, GI19913406, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=3e-13, Organism=Escherichia coli, GI1788562, Length=850, Percent_Identity=55.8823529411765, Blast_Score=941, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=675, Percent_Identity=36.2962962962963, Blast_Score=403, Evalue=1e-113, Organism=Caenorhabditis elegans, GI212645845, Length=309, Percent_Identity=24.9190938511327, Blast_Score=74, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17535065, Length=178, Percent_Identity=30.8988764044944, Blast_Score=72, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI17136538, Length=364, Percent_Identity=26.0989010989011, Blast_Score=75, Evalue=2e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 93899; Mature: 93899
Theoretical pI: Translated: 5.15; Mature: 5.15
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNQLNKVSVNIEDEMKRSYMDYAMSVIVGRALPDVRDGLKPVHRRCLFAMYDMSNDWNK CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC PYKKSARVVGDVIGKYHPHGDTAVYDTLVRMAQDFSLRYPLVDGQGNFGSIDGDSPAAMR CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEECEEECCCCCCCCCCCCCCCHHH YTEIRMEQLAHELLADIDKETVPYGPNYDDSLKEPLVLPSKFPNLLVNGSAGIAVGMATN HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECC IPPHNLSEVIDGIVAIIDNPQLTFEELVELIPGPDFPTGGFIYGREGIMKAYSTGRGIIQ CCCCCHHHHHHHHHEEECCCCCCHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCCEEE MRAKVQIETQKKTERQSIVVTEIPYQVNKARLVEKIAELVKEKKIEGISDLRDESDREGM EEEEEEEEEHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCE RVVIELKKDENPTIILNHLYKQTQMQSSFGIIMLAIVNSRPRVLTLRETIDFFIEHRKEI EEEEEEECCCCCEEEHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHH VTRRTIFDLKKAEARAHILEGLKIALDNLDEVIALIKASASPAEAKAGLMERFGLSDLQA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHH QAILDMRLHRLTGLEREKIMEELREILKYIARLKEILASEAEILKIIVGELVELKDKFGD HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC KRRSEIVMQTADISLEDTIVEEDMVVTISHTGYIKRNAVTLYRAQRRGGKGKTGMKTKEE HHHHHEEEEECCCCHHHHEECCCEEEEEECCCEEEECCEEEEEHHHCCCCCCCCCCCCHH DFVEQLFIASTKDYLMFFTDAGKVYWLKVYEIPEAGRAARGKAIVNLLNLAANEKITTIL HHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEE PVKEFVDDKFIMMATRNGVVKKTNMMEYSHPRVGGIIAVNLDEGDKLITVALTDGKQDVL CHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCEEE LASANGKAIRFKEEDVRTVGRVSRGVRGMTLEGEDVVIGMEILNENFTDSTIFTVTENGY EEECCCCEEEEEHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHCCCCCCCEEEEEECCCC GKRTEISEYRSQSRGGKGVITIKTTERNGNVVDIKQVNDDNDLMLITDQGKILRVPVAGF CCCCHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEEECCE SIIGRNTQGVRLMVKEENERVVAVARLAEKEEQDESEDGELDEMVELESGEEQGEE EEECCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCC >Mature Secondary Structure MLNQLNKVSVNIEDEMKRSYMDYAMSVIVGRALPDVRDGLKPVHRRCLFAMYDMSNDWNK CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC PYKKSARVVGDVIGKYHPHGDTAVYDTLVRMAQDFSLRYPLVDGQGNFGSIDGDSPAAMR CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEECEEECCCCCCCCCCCCCCCHHH YTEIRMEQLAHELLADIDKETVPYGPNYDDSLKEPLVLPSKFPNLLVNGSAGIAVGMATN HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECC IPPHNLSEVIDGIVAIIDNPQLTFEELVELIPGPDFPTGGFIYGREGIMKAYSTGRGIIQ CCCCCHHHHHHHHHEEECCCCCCHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCCEEE MRAKVQIETQKKTERQSIVVTEIPYQVNKARLVEKIAELVKEKKIEGISDLRDESDREGM EEEEEEEEEHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCE RVVIELKKDENPTIILNHLYKQTQMQSSFGIIMLAIVNSRPRVLTLRETIDFFIEHRKEI EEEEEEECCCCCEEEHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHH VTRRTIFDLKKAEARAHILEGLKIALDNLDEVIALIKASASPAEAKAGLMERFGLSDLQA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHH QAILDMRLHRLTGLEREKIMEELREILKYIARLKEILASEAEILKIIVGELVELKDKFGD HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC KRRSEIVMQTADISLEDTIVEEDMVVTISHTGYIKRNAVTLYRAQRRGGKGKTGMKTKEE HHHHHEEEEECCCCHHHHEECCCEEEEEECCCEEEECCEEEEEHHHCCCCCCCCCCCCHH DFVEQLFIASTKDYLMFFTDAGKVYWLKVYEIPEAGRAARGKAIVNLLNLAANEKITTIL HHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEE PVKEFVDDKFIMMATRNGVVKKTNMMEYSHPRVGGIIAVNLDEGDKLITVALTDGKQDVL CHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCEEE LASANGKAIRFKEEDVRTVGRVSRGVRGMTLEGEDVVIGMEILNENFTDSTIFTVTENGY EEECCCCEEEEEHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHCCCCCCCEEEEEECCCC GKRTEISEYRSQSRGGKGVITIKTTERNGNVVDIKQVNDDNDLMLITDQGKILRVPVAGF CCCCHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEEECCE SIIGRNTQGVRLMVKEENERVVAVARLAEKEEQDESEDGELDEMVELESGEEQGEE EEECCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11677609; 8849216 [H]