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The map label for this gene is argS

Identifier: 197106356

GI number: 197106356

Start: 3305517

End: 3307298

Strand: Direct

Name: argS

Synonym: PHZ_c2895

Alternate gene names: 197106356

Gene position: 3305517-3307298 (Clockwise)

Preceding gene: 197106355

Following gene: 197106358

Centisome position: 82.72

GC content: 71.72

Gene sequence:

>1782_bases
ATGAGCGACCTGAAGACGGCGCTCGGCGAGGCGGTGGAAGCCGCCTTCGCCGCCGAAGGCGTTCCCGCAGAGCTCGCCCG
CGTCACCGCCTCCGACCGCCCCGATCTGGCCGACTTCCAGTCGAACGGCGCCCTCGCCGCGGCCAAGCGCGTGGGGAAGA
ACCCGCGCGAGATCGCGACCGCCGTGGCCGGCCGCCTGCAGGGCGATCCGCGCCTGGCCTCGGTCGAGATCGCCGGCCCG
GGCTTCCTGAACCTGAAGGTGGCCGACGCCGCCCTCGCCGCCCGCGCCGACGCCATCGCCGCCGACCCGCGCGCCGGAGC
CGGGACCGTGCCGGCGCCCCGCCGGGTGATCGTCGACTACGGCGGCCCCAACGTCGCCAAGCCGATGCACGTGGGCCACC
TGCGCGCCTCGATCATCGGCGAGTCCGTCAAGCGCCTCTACCGCTTCCGCGGCGACACCGTGATCGGCGACGCCCACTTC
GGCGACTGGGGCTACCAGATGGGCCTGCTGATCGGCGCCGTCTGCGACGAGGACGCCGAGATCCGCGCCCTGGTGGACCA
GCTCAACGCCTCTGGGGATCCAAACGGCGAGATCCCGGCCGCCTTCGAGCGCGTCACCCTGGCCGACCTCGACCGGCTCT
ATCCCCTGGCCGCCGCCAAGGGGAAGGAGGACCCCGCCTACCGCGACCGGGCCCGCAAGCTCACCGCCGACCTCCAGGCC
CACAAGCCCGGCTGCTACCTGCTGTGGCGCCGCTTCCGGGACGTGACCCAGGTCGCCCTCGAGCGCGACTTCCATGCCCT
GGGCGTCGACTTTGACTGGTGGAAGGGCGAGAGCGACGTCGACCATCTGATCCAGCCCATGGTGGCCGAACTCGCCGACA
AGGGCCTGCTCGTCGACGACCAGGGCGCCCGGATCGTCCGTGTCGCCCGCGAGGGGGACAAGCGCGAGCTGCCGCCGCTG
CTGGTGGTCTCCTCCGAAGGCTCGGCGATGTACGGCACGACCGACCTGGCCACCATCCTCGACCGCAAGCGCGAGTTCGA
TCCGCAGCTCGTCATCTACTGCGTCGACCAGCGCCAGGCCGACCACTTCGAGATCGTCTTCCGCGCCGCCTACCTCGCCG
GCTACGCCGAAGAGGGCCAGCTCGAGCACATCGGCTTCGGCACGATGAACGGGACCGACGGCAAGCCCTTCAAGACCCGC
GAGGGCGGCGTCCTCAAGCTCGCCGACCTCATCGAGATGACCAGGTCCAAGGCCCGCGAGCGCCTGCACGAGGCCGGCCT
CGGCGAGGACCTGCCGGCCGAGGAATTCGAGGACATCGCGGGCAAGGTGGCGGTGGCGGCCCTGAAGTTCGCCGACCTCT
CCAACTTCCGCGGCACCTCCTACGTCTTCGACCTCGACCGCTTCACCAGCTTCGAGGGCAAGACCGGCCCCTACCTGCTC
TACCAGGCGGTGCGGGTGAAATCCCTGCTGCGCAAGGCCGAGGCCGAGGGCGCCCAGGCCGGCCCGGTCACCGTGGCCGA
GCCCGCCGAGCGCGACCTCGTGCTGACCCTCGACGCCTTCGAGACCGCCCTGCAGGAGGCCTACGACAAGAAGGCCCCCA
ACGCCCTGGCCGAGCACGCCTACCGGCTCTCCCAGGCGTTCTCGAAGTTCTACGCCGCCTGCCCGATCCTGGCCGCCCCG
CCGCCGGTCCGGGGCTCGCGCCTGACCCTGGCCCAGGCCACGCTGCGCCAGCTCGAACTGGCGCTGGACATCCTCGGCAT
CGCGGTCCCCGAGAGGATGTAG

Upstream 100 bases:

>100_bases
TCACCCCGCAGATGGCCGCCTTCAACCGTGAGGGCAAGCGCTTCCGCCTGAACGTCGGCGCGCCGACCGAGACCGCGCAA
ACCGGAACCGCCCCGCCGCA

Downstream 100 bases:

>100_bases
GGGATATAACGACAATATATAACGTCGTTATTTGGATTAGTTCTGTAGGTCGACTCCGCCTCTTCTGATCTCAAGGCGCG
CCCGGCTTGTCTGGACTCCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MSDLKTALGEAVEAAFAAEGVPAELARVTASDRPDLADFQSNGALAAAKRVGKNPREIATAVAGRLQGDPRLASVEIAGP
GFLNLKVADAALAARADAIAADPRAGAGTVPAPRRVIVDYGGPNVAKPMHVGHLRASIIGESVKRLYRFRGDTVIGDAHF
GDWGYQMGLLIGAVCDEDAEIRALVDQLNASGDPNGEIPAAFERVTLADLDRLYPLAAAKGKEDPAYRDRARKLTADLQA
HKPGCYLLWRRFRDVTQVALERDFHALGVDFDWWKGESDVDHLIQPMVAELADKGLLVDDQGARIVRVAREGDKRELPPL
LVVSSEGSAMYGTTDLATILDRKREFDPQLVIYCVDQRQADHFEIVFRAAYLAGYAEEGQLEHIGFGTMNGTDGKPFKTR
EGGVLKLADLIEMTRSKARERLHEAGLGEDLPAEEFEDIAGKVAVAALKFADLSNFRGTSYVFDLDRFTSFEGKTGPYLL
YQAVRVKSLLRKAEAEGAQAGPVTVAEPAERDLVLTLDAFETALQEAYDKKAPNALAEHAYRLSQAFSKFYAACPILAAP
PPVRGSRLTLAQATLRQLELALDILGIAVPERM

Sequences:

>Translated_593_residues
MSDLKTALGEAVEAAFAAEGVPAELARVTASDRPDLADFQSNGALAAAKRVGKNPREIATAVAGRLQGDPRLASVEIAGP
GFLNLKVADAALAARADAIAADPRAGAGTVPAPRRVIVDYGGPNVAKPMHVGHLRASIIGESVKRLYRFRGDTVIGDAHF
GDWGYQMGLLIGAVCDEDAEIRALVDQLNASGDPNGEIPAAFERVTLADLDRLYPLAAAKGKEDPAYRDRARKLTADLQA
HKPGCYLLWRRFRDVTQVALERDFHALGVDFDWWKGESDVDHLIQPMVAELADKGLLVDDQGARIVRVAREGDKRELPPL
LVVSSEGSAMYGTTDLATILDRKREFDPQLVIYCVDQRQADHFEIVFRAAYLAGYAEEGQLEHIGFGTMNGTDGKPFKTR
EGGVLKLADLIEMTRSKARERLHEAGLGEDLPAEEFEDIAGKVAVAALKFADLSNFRGTSYVFDLDRFTSFEGKTGPYLL
YQAVRVKSLLRKAEAEGAQAGPVTVAEPAERDLVLTLDAFETALQEAYDKKAPNALAEHAYRLSQAFSKFYAACPILAAP
PPVRGSRLTLAQATLRQLELALDILGIAVPERM
>Mature_592_residues
SDLKTALGEAVEAAFAAEGVPAELARVTASDRPDLADFQSNGALAAAKRVGKNPREIATAVAGRLQGDPRLASVEIAGPG
FLNLKVADAALAARADAIAADPRAGAGTVPAPRRVIVDYGGPNVAKPMHVGHLRASIIGESVKRLYRFRGDTVIGDAHFG
DWGYQMGLLIGAVCDEDAEIRALVDQLNASGDPNGEIPAAFERVTLADLDRLYPLAAAKGKEDPAYRDRARKLTADLQAH
KPGCYLLWRRFRDVTQVALERDFHALGVDFDWWKGESDVDHLIQPMVAELADKGLLVDDQGARIVRVAREGDKRELPPLL
VVSSEGSAMYGTTDLATILDRKREFDPQLVIYCVDQRQADHFEIVFRAAYLAGYAEEGQLEHIGFGTMNGTDGKPFKTRE
GGVLKLADLIEMTRSKARERLHEAGLGEDLPAEEFEDIAGKVAVAALKFADLSNFRGTSYVFDLDRFTSFEGKTGPYLLY
QAVRVKSLLRKAEAEGAQAGPVTVAEPAERDLVLTLDAFETALQEAYDKKAPNALAEHAYRLSQAFSKFYAACPILAAPP
PVRGSRLTLAQATLRQLELALDILGIAVPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=615, Percent_Identity=31.219512195122, Blast_Score=272, Evalue=6e-73,
Organism=Homo sapiens, GI197100773, Length=590, Percent_Identity=26.1016949152542, Blast_Score=173, Evalue=5e-43,
Organism=Escherichia coli, GI1788184, Length=599, Percent_Identity=38.2303839732888, Blast_Score=352, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI71985061, Length=614, Percent_Identity=27.5244299674267, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71985068, Length=574, Percent_Identity=27.7003484320557, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17532153, Length=500, Percent_Identity=24.8, Blast_Score=123, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320548, Length=555, Percent_Identity=26.8468468468468, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321883, Length=485, Percent_Identity=25.360824742268, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI18859963, Length=612, Percent_Identity=29.2483660130719, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI28571570, Length=492, Percent_Identity=27.2357723577236, Blast_Score=138, Evalue=9e-33,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PHEZH (B4R8T9)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131733.1
- ProteinModelPortal:   B4R8T9
- GeneID:   6788842
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2895
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64242; Mature: 64110

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKTALGEAVEAAFAAEGVPAELARVTASDRPDLADFQSNGALAAAKRVGKNPREIAT
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCHHHHHH
AVAGRLQGDPRLASVEIAGPGFLNLKVADAALAARADAIAADPRAGAGTVPAPRRVIVDY
HHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
GGPNVAKPMHVGHLRASIIGESVKRLYRFRGDTVIGDAHFGDWGYQMGLLIGAVCDEDAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCHH
IRALVDQLNASGDPNGEIPAAFERVTLADLDRLYPLAAAKGKEDPAYRDRARKLTADLQA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
HKPGCYLLWRRFRDVTQVALERDFHALGVDFDWWKGESDVDHLIQPMVAELADKGLLVDD
CCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
QGARIVRVAREGDKRELPPLLVVSSEGSAMYGTTDLATILDRKREFDPQLVIYCVDQRQA
CCCEEEEEECCCCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCCEEEEEECCCCC
DHFEIVFRAAYLAGYAEEGQLEHIGFGTMNGTDGKPFKTREGGVLKLADLIEMTRSKARE
CHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
RLHEAGLGEDLPAEEFEDIAGKVAVAALKFADLSNFRGTSYVFDLDRFTSFEGKTGPYLL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCHHH
YQAVRVKSLLRKAEAEGAQAGPVTVAEPAERDLVLTLDAFETALQEAYDKKAPNALAEHA
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHH
YRLSQAFSKFYAACPILAAPPPVRGSRLTLAQATLRQLELALDILGIAVPERM
HHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDLKTALGEAVEAAFAAEGVPAELARVTASDRPDLADFQSNGALAAAKRVGKNPREIAT
CHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCHHHHHH
AVAGRLQGDPRLASVEIAGPGFLNLKVADAALAARADAIAADPRAGAGTVPAPRRVIVDY
HHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
GGPNVAKPMHVGHLRASIIGESVKRLYRFRGDTVIGDAHFGDWGYQMGLLIGAVCDEDAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCHH
IRALVDQLNASGDPNGEIPAAFERVTLADLDRLYPLAAAKGKEDPAYRDRARKLTADLQA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
HKPGCYLLWRRFRDVTQVALERDFHALGVDFDWWKGESDVDHLIQPMVAELADKGLLVDD
CCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
QGARIVRVAREGDKRELPPLLVVSSEGSAMYGTTDLATILDRKREFDPQLVIYCVDQRQA
CCCEEEEEECCCCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHCCCCCEEEEEECCCCC
DHFEIVFRAAYLAGYAEEGQLEHIGFGTMNGTDGKPFKTREGGVLKLADLIEMTRSKARE
CHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
RLHEAGLGEDLPAEEFEDIAGKVAVAALKFADLSNFRGTSYVFDLDRFTSFEGKTGPYLL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCHHH
YQAVRVKSLLRKAEAEGAQAGPVTVAEPAERDLVLTLDAFETALQEAYDKKAPNALAEHA
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHH
YRLSQAFSKFYAACPILAAPPPVRGSRLTLAQATLRQLELALDILGIAVPERM
HHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA