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The map label for this gene is gdhII [H]

Identifier: 197106309

GI number: 197106309

Start: 3264398

End: 3265126

Strand: Direct

Name: gdhII [H]

Synonym: PHZ_c2848

Alternate gene names: 197106309

Gene position: 3264398-3265126 (Clockwise)

Preceding gene: 197106305

Following gene: 197106310

Centisome position: 81.69

GC content: 74.49

Gene sequence:

>729_bases
GTGGCCAGCCGCGGCGCGGCTCTGGTGACGGGCGGCGCGCGGCGGCTGGGCCGCGTGCTGGCGACGACGGCCGCCCAGGC
CGGCTATGACGTCGCCATCCACGTCCGCGCGGTGGACGACGCCGCCGAGGCGGCCGCCCAGGAGGTCCGCGCCTGCGGCC
GCCGCGCCGCGCTCCTCGCCTGCGACCTGCGCAAGGAGTCCACGACGGTGGCCCTGGTCGGCGAGGCCGAGGCCGAGCTC
GGCCCCGTGACCCTGCTGGTCAACTCGGCCAGCGTCTTCGAGAACGACGCCTTCGCGGACATGAACCGGGCCTCGTGGGA
CCTGCACCTCGAGACCAACCTGCGCGCGCCGCTGGTGCTGGCCCAGGCCTTCGCCCGCCGCCTGCCGGCCGACCGCGACG
GCCTGATCGTCAACGTCCTCGACCAGCGGGTGCTGAACCCGCGCCCCGAGTTCTTCTCCTATTCGCTCAGCAAGTCCGCC
CTGTGGGACGCCACCCGCATGCTGGCCGTGGCGCTGGCGCCGCGCATCCGGGTGAACGGCATCGGACCCGGCCCGACCCT
GCCGTCGATCCACCAGGACCAGGACGCCTTCGACGCCGAGGCCGCGTCCACCCTGCTCGGCCGCCCTGTGCCGCCCGCCG
AGATCGGCGCGGCCCTGCGCTACCTGATCGACGCCGGCTCGGTGACCGGCCAGATGATCGCCGTCGATTCCGGACAACAC
CTGTCGTGA

Upstream 100 bases:

>100_bases
GTGATCGGGATCTACGCCATCGGCATCTTCCTCCTCGTGATGATCGCGCTGAACGTCTACGAGTTCGGCCGCATCGACTG
AGGCCGAAGGACCGTCCCCG

Downstream 100 bases:

>100_bases
GCGGCGCCCGCCTCAGCGCCAGCAAGGTGTTCGTCACCGGCCTGCAGGTCCAGGCGCAGATCGGCGTCTATCGCCACGAG
ATCGGCCGGGTGCAGCCCCT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MASRGAALVTGGARRLGRVLATTAAQAGYDVAIHVRAVDDAAEAAAQEVRACGRRAALLACDLRKESTTVALVGEAEAEL
GPVTLLVNSASVFENDAFADMNRASWDLHLETNLRAPLVLAQAFARRLPADRDGLIVNVLDQRVLNPRPEFFSYSLSKSA
LWDATRMLAVALAPRIRVNGIGPGPTLPSIHQDQDAFDAEAASTLLGRPVPPAEIGAALRYLIDAGSVTGQMIAVDSGQH
LS

Sequences:

>Translated_242_residues
MASRGAALVTGGARRLGRVLATTAAQAGYDVAIHVRAVDDAAEAAAQEVRACGRRAALLACDLRKESTTVALVGEAEAEL
GPVTLLVNSASVFENDAFADMNRASWDLHLETNLRAPLVLAQAFARRLPADRDGLIVNVLDQRVLNPRPEFFSYSLSKSA
LWDATRMLAVALAPRIRVNGIGPGPTLPSIHQDQDAFDAEAASTLLGRPVPPAEIGAALRYLIDAGSVTGQMIAVDSGQH
LS
>Mature_241_residues
ASRGAALVTGGARRLGRVLATTAAQAGYDVAIHVRAVDDAAEAAAQEVRACGRRAALLACDLRKESTTVALVGEAEAELG
PVTLLVNSASVFENDAFADMNRASWDLHLETNLRAPLVLAQAFARRLPADRDGLIVNVLDQRVLNPRPEFFSYSLSKSAL
WDATRMLAVALAPRIRVNGIGPGPTLPSIHQDQDAFDAEAASTLLGRPVPPAEIGAALRYLIDAGSVTGQMIAVDSGQHL
S

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=29.957805907173, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=31.4285714285714, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=31.5352697095436, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=28.2868525896414, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=26.4462809917355, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=27.7551020408163, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=27.6859504132231, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787891, Length=245, Percent_Identity=26.530612244898, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI87082160, Length=179, Percent_Identity=27.9329608938547, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=30.0813008130081, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.4354838709677, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=27.710843373494, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=29.5546558704453, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=26.7441860465116, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=29.3877551020408, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=28.5140562248996, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=29.9180327868852, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=29.7959183673469, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 25499; Mature: 25368

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRGAALVTGGARRLGRVLATTAAQAGYDVAIHVRAVDDAAEAAAQEVRACGRRAALLA
CCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCHHHEEEE
CDLRKESTTVALVGEAEAELGPVTLLVNSASVFENDAFADMNRASWDLHLETNLRAPLVL
EECCCCCCEEEEEECCCCCCCCEEEEEECHHHHCCCCHHCCCCCEEEEEEECCCCCHHHH
AQAFARRLPADRDGLIVNVLDQRVLNPRPEFFSYSLSKSALWDATRMLAVALAPRIRVNG
HHHHHHHCCCCCCCEEEEEHHHHHCCCCCCHHEECCCHHHHHHHHHHHHHHHCCCEEEEC
IGPGPTLPSIHQDQDAFDAEAASTLLGRPVPPAEIGAALRYLIDAGSVTGQMIAVDSGQH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
LS
CC
>Mature Secondary Structure 
ASRGAALVTGGARRLGRVLATTAAQAGYDVAIHVRAVDDAAEAAAQEVRACGRRAALLA
CCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCHHHEEEE
CDLRKESTTVALVGEAEAELGPVTLLVNSASVFENDAFADMNRASWDLHLETNLRAPLVL
EECCCCCCEEEEEECCCCCCCCEEEEEECHHHHCCCCHHCCCCCEEEEEEECCCCCHHHH
AQAFARRLPADRDGLIVNVLDQRVLNPRPEFFSYSLSKSALWDATRMLAVALAPRIRVNG
HHHHHHHCCCCCCCEEEEEHHHHHCCCCCCHHEECCCHHHHHHHHHHHHHHHCCCEEEEC
IGPGPTLPSIHQDQDAFDAEAASTLLGRPVPPAEIGAALRYLIDAGSVTGQMIAVDSGQH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA