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The map label for this gene is aroC

Identifier: 197106201

GI number: 197106201

Start: 3141447

End: 3142580

Strand: Direct

Name: aroC

Synonym: PHZ_c2740

Alternate gene names: 197106201

Gene position: 3141447-3142580 (Clockwise)

Preceding gene: 197106200

Following gene: 197106202

Centisome position: 78.61

GC content: 72.31

Gene sequence:

>1134_bases
ATGTCGCACAACACCTTCGGCCACCTATTCCGCGTCACCACCTGGGGCGAGAGCCACGGGCCGGCGCTGGGCTGCGTGGT
CGACGGCTGCCCGCCGGGCGTCCCGCTGACCGAGGCCGACATCCAGCCCTGGCTCGACCGTCGCCGGCCCGGCCAGGGCA
AGTTCGTCACCCAGCGCCAGGAGCCGGACGCGGTCCGCATCCTCTCCGGCGTGTTCCAGGACGAACGGACGACCGCGAAG
TTCGGGGGCCAGGTGACCACCGGCACGCCCATCTCGCTGATCATCGAGAACACCGACCAGCGCAGCCGCGACTATTCCGA
GATCGCCACCAGCTTCCGACCCGGGCACGCCGACTATCCCTACTTCGCCAAGTACGGGGTCCGCGACTACCGGGGCGGCG
GCCGATCCTCGGCCCGCGAGACCGCCGCGCGCGTCGCCGCCGGAGCGATCGCCCGCAAGCTGCTGCCCGGCGTCACCATC
CGGGGCGCCGTCGTCCAGATCGGGCCGCATGCGGTGGATCCCGGACGGATCGACTTCTCGGTCACCGGCGACAATCCGTT
CTGGGCGCCCGACCCCGAGATCGTCCCGGTCTGGGAGAGGCACCTGGAGCAGGTCCGCAAGGCGGGATCCTCGACCGGCG
CCGTGGTCGCCGTGGAGGCAACGGGCGTACCGGCCGGCTGGGGCGCGCCGCTCTACGGCAAGCTGGACGCCGAGCTGGCC
GCCGCGCTCATGTCGATCAACGCGGCCAAGGGGGTCGAGATCGGCGCGGGCTTCGCCGCCGCCGCGCTGTCGGGCGAAGA
GAACGCCGACGAGATGCGGATGGGGAACGAGGGCCCGCTCTTCCTCTCCAACAAAGCCGGCGGCGTGCTGGGCGGGATCT
CCACCGGCCAGCCGGTGACCGCCCGCGTCGCGTTCAAGCCGACCTCCTCCATCCTCACCCCGCGCCGCAGCCTCGACGAG
GCGGGCCGCGAGATCGAGCTGCGCACCAAGGGCCGCCACGACCCGTGCGTCGGCATCCGCGCCGTGCCGGTGGTCGAGGC
GATGGTCGCCTGCGTCCTCGCCGACGCCTTGTTGCGTCATCGCGCGCAGACCGGCGGCGGCGCCCACGTCTTGGGCGAAA
ACCCAAAGTCGTGA

Upstream 100 bases:

>100_bases
TCCCTGCTTCGCCGCTTCGCCGCCGCCTGGGCTGCGTAGAGTGGGCCGCGTGAGCGGGCCGTTTGTGGCGCTTCCGGGGT
TCGGCTAAGGAAGCCCGGCC

Downstream 100 bases:

>100_bases
ACCCGACGTTGCAGACAGTTTCTACGCAACGATAGGTCACTGGACTCAACGGTTTAAAGGATAACCTGTTACAGCAACGC
CATTGACCGGCGATTACGGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGVPLTEADIQPWLDRRRPGQGKFVTQRQEPDAVRILSGVFQDERTTAK
FGGQVTTGTPISLIIENTDQRSRDYSEIATSFRPGHADYPYFAKYGVRDYRGGGRSSARETAARVAAGAIARKLLPGVTI
RGAVVQIGPHAVDPGRIDFSVTGDNPFWAPDPEIVPVWERHLEQVRKAGSSTGAVVAVEATGVPAGWGAPLYGKLDAELA
AALMSINAAKGVEIGAGFAAAALSGEENADEMRMGNEGPLFLSNKAGGVLGGISTGQPVTARVAFKPTSSILTPRRSLDE
AGREIELRTKGRHDPCVGIRAVPVVEAMVACVLADALLRHRAQTGGGAHVLGENPKS

Sequences:

>Translated_377_residues
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGVPLTEADIQPWLDRRRPGQGKFVTQRQEPDAVRILSGVFQDERTTAK
FGGQVTTGTPISLIIENTDQRSRDYSEIATSFRPGHADYPYFAKYGVRDYRGGGRSSARETAARVAAGAIARKLLPGVTI
RGAVVQIGPHAVDPGRIDFSVTGDNPFWAPDPEIVPVWERHLEQVRKAGSSTGAVVAVEATGVPAGWGAPLYGKLDAELA
AALMSINAAKGVEIGAGFAAAALSGEENADEMRMGNEGPLFLSNKAGGVLGGISTGQPVTARVAFKPTSSILTPRRSLDE
AGREIELRTKGRHDPCVGIRAVPVVEAMVACVLADALLRHRAQTGGGAHVLGENPKS
>Mature_376_residues
SHNTFGHLFRVTTWGESHGPALGCVVDGCPPGVPLTEADIQPWLDRRRPGQGKFVTQRQEPDAVRILSGVFQDERTTAKF
GGQVTTGTPISLIIENTDQRSRDYSEIATSFRPGHADYPYFAKYGVRDYRGGGRSSARETAARVAAGAIARKLLPGVTIR
GAVVQIGPHAVDPGRIDFSVTGDNPFWAPDPEIVPVWERHLEQVRKAGSSTGAVVAVEATGVPAGWGAPLYGKLDAELAA
ALMSINAAKGVEIGAGFAAAALSGEENADEMRMGNEGPLFLSNKAGGVLGGISTGQPVTARVAFKPTSSILTPRRSLDEA
GREIELRTKGRHDPCVGIRAVPVVEAMVACVLADALLRHRAQTGGGAHVLGENPKS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=367, Percent_Identity=59.1280653950954, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=44.0318302387268, Blast_Score=285, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PHEZH (B4RHV8)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131578.1
- ProteinModelPortal:   B4RHV8
- GeneID:   6792264
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2740
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39781; Mature: 39650

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGVPLTEADIQPWLDRRRPGQGKFVTQRQ
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCEEECCC
EPDAVRILSGVFQDERTTAKFGGQVTTGTPISLIIENTDQRSRDYSEIATSFRPGHADYP
CCCHHHHHHHHHHCCCHHHHHCCEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCC
YFAKYGVRDYRGGGRSSARETAARVAAGAIARKLLPGVTIRGAVVQIGPHAVDPGRIDFS
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCCEEEE
VTGDNPFWAPDPEIVPVWERHLEQVRKAGSSTGAVVAVEATGVPAGWGAPLYGKLDAELA
EECCCCCCCCCCCEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHH
AALMSINAAKGVEIGAGFAAAALSGEENADEMRMGNEGPLFLSNKAGGVLGGISTGQPVT
HHHHHHHCCCCCEECCCHHHEECCCCCCHHHHHCCCCCCEEEECCCCCEEECCCCCCCEE
ARVAFKPTSSILTPRRSLDEAGREIELRTKGRHDPCVGIRAVPVVEAMVACVLADALLRH
EEEEECCCHHHCCCHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RAQTGGGAHVLGENPKS
HHCCCCCEEECCCCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTWGESHGPALGCVVDGCPPGVPLTEADIQPWLDRRRPGQGKFVTQRQ
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCEEECCC
EPDAVRILSGVFQDERTTAKFGGQVTTGTPISLIIENTDQRSRDYSEIATSFRPGHADYP
CCCHHHHHHHHHHCCCHHHHHCCEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCC
YFAKYGVRDYRGGGRSSARETAARVAAGAIARKLLPGVTIRGAVVQIGPHAVDPGRIDFS
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCCEEEE
VTGDNPFWAPDPEIVPVWERHLEQVRKAGSSTGAVVAVEATGVPAGWGAPLYGKLDAELA
EECCCCCCCCCCCEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHH
AALMSINAAKGVEIGAGFAAAALSGEENADEMRMGNEGPLFLSNKAGGVLGGISTGQPVT
HHHHHHHCCCCCEECCCHHHEECCCCCCHHHHHCCCCCCEEEECCCCCEEECCCCCCCEE
ARVAFKPTSSILTPRRSLDEAGREIELRTKGRHDPCVGIRAVPVVEAMVACVLADALLRH
EEEEECCCHHHCCCHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RAQTGGGAHVLGENPKS
HHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA