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The map label for this gene is ahpC [H]

Identifier: 197106185

GI number: 197106185

Start: 3120576

End: 3121139

Strand: Direct

Name: ahpC [H]

Synonym: PHZ_c2724

Alternate gene names: 197106185

Gene position: 3120576-3121139 (Clockwise)

Preceding gene: 197106184

Following gene: 197106186

Centisome position: 78.09

GC content: 62.94

Gene sequence:

>564_bases
ATGTCTCTGATCAACACCGAGGTGAAGCCCTTCACCGCTCAAGCCTACAAGGACGGCAAGTTCCTGACCGTCAGCGACAG
CGACCTGAAGGGCAAGTGGTCGGTCGTCTTCTTCTATCCTGCCGACTTCACCTTCGTCTGCCCGACCGAGCTCGAGGACC
TGGCCGACAACTACGCCGAGTTCCAGAAGCTGGGCGTCGAGATCTATTCGGTGTCGACGGATACGCACTTCTCGCACAAG
GCCTGGGCCGACACCTCGCCGGCCATCGGCAAGATCAAGTACGTGATGGTGGGCGACCCCTCGGGCGTCATCACCAACAA
CTTCGGCGTGATGCGTGAAGGCCAGGGCCTGGCCGACCGCGGCACCTTCCTGGTCGACCCCGACGGCGTCATCCAGTTCA
TGGAGATCACCGCCGAAGGCATCGGCCGCAACGCCGCCGAACTGCTGCGCAAGGTGAAGGCCGCCAAGTACGTGCGCGAG
CACCCCGGCGAAGTCTGCCCGGCCAAGTGGGAAGAAGGCGAGAAGACCCTCGCTCCGTCCCTGGACCTGGTCGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
CACCCATAGATCTTTTCGATGACCGGGGCTTTAGAAAATCAATTTTCCTAATGACCTCGGACCCTCTAGGACAGCAGCCG
ACGTCAACCGGGAGAACCCA

Downstream 100 bases:

>100_bases
GCCCGACTTCGACGACCCGCCGGCGCCGCGCCTCCTTAGCGCGCGGCGCCGGCGCCATCGCCCTTCCTCCCCCCCCCCGA
GACCCCGGAGTCCCATGCTG

Product: alkyl hydroperoxide reductase, subunit c

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLINTEVKPFTAQAYKDGKFLTVSDSDLKGKWSVVFFYPADFTFVCPTELEDLADNYAEFQKLGVEIYSVSTDTHFSHK
AWADTSPAIGKIKYVMVGDPSGVITNNFGVMREGQGLADRGTFLVDPDGVIQFMEITAEGIGRNAAELLRKVKAAKYVRE
HPGEVCPAKWEEGEKTLAPSLDLVGKI

Sequences:

>Translated_187_residues
MSLINTEVKPFTAQAYKDGKFLTVSDSDLKGKWSVVFFYPADFTFVCPTELEDLADNYAEFQKLGVEIYSVSTDTHFSHK
AWADTSPAIGKIKYVMVGDPSGVITNNFGVMREGQGLADRGTFLVDPDGVIQFMEITAEGIGRNAAELLRKVKAAKYVRE
HPGEVCPAKWEEGEKTLAPSLDLVGKI
>Mature_186_residues
SLINTEVKPFTAQAYKDGKFLTVSDSDLKGKWSVVFFYPADFTFVCPTELEDLADNYAEFQKLGVEIYSVSTDTHFSHKA
WADTSPAIGKIKYVMVGDPSGVITNNFGVMREGQGLADRGTFLVDPDGVIQFMEITAEGIGRNAAELLRKVKAAKYVREH
PGEVCPAKWEEGEKTLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=43.9306358381503, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=43.9306358381503, Blast_Score=156, Evalue=8e-39,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=41.1428571428571, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI4505591, Length=167, Percent_Identity=40.1197604790419, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI32455266, Length=167, Percent_Identity=40.1197604790419, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI32455264, Length=167, Percent_Identity=40.1197604790419, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI5453549, Length=173, Percent_Identity=38.150289017341, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=50.6493506493506, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=68.9839572192513, Blast_Score=291, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=42.3728813559322, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=39.344262295082, Blast_Score=143, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=39.344262295082, Blast_Score=142, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=29.8780487804878, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=32.5966850828729, Blast_Score=115, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323613, Length=185, Percent_Identity=32.972972972973, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=162, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=37.2881355932203, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=37.9120879120879, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=37.3626373626374, Blast_Score=133, Evalue=8e-32,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=37.3626373626374, Blast_Score=133, Evalue=8e-32,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=36.6666666666667, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=36.6666666666667, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=31.0126582278481, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=28.4810126582279, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=28.4810126582279, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=28.4810126582279, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20591; Mature: 20459

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTEVKPFTAQAYKDGKFLTVSDSDLKGKWSVVFFYPADFTFVCPTELEDLADNYAE
CCCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYSVSTDTHFSHKAWADTSPAIGKIKYVMVGDPSGVITNNFGVMREGQGLADR
HHHCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCCEECCCCCCCC
GTFLVDPDGVIQFMEITAEGIGRNAAELLRKVKAAKYVREHPGEVCPAKWEEGEKTLAPS
CCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
LDLVGKI
CHHHCCC
>Mature Secondary Structure 
SLINTEVKPFTAQAYKDGKFLTVSDSDLKGKWSVVFFYPADFTFVCPTELEDLADNYAE
CCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYSVSTDTHFSHKAWADTSPAIGKIKYVMVGDPSGVITNNFGVMREGQGLADR
HHHCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCCEECCCCCCCC
GTFLVDPDGVIQFMEITAEGIGRNAAELLRKVKAAKYVREHPGEVCPAKWEEGEKTLAPS
CCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCC
LDLVGKI
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]