Click here to switch to the map view.

The map label for this gene is pleC [H]

Identifier: 197106142

GI number: 197106142

Start: 3073994

End: 3075859

Strand: Direct

Name: pleC [H]

Synonym: PHZ_c2681

Alternate gene names: 197106142

Gene position: 3073994-3075859 (Clockwise)

Preceding gene: 197106141

Following gene: 197106160

Centisome position: 76.92

GC content: 72.45

Gene sequence:

>1866_bases
TTGGCCAAGGGCGGGGGGCGAAAGGCGGCAGGCGGAGCGCGTCCGGCGCTGGCCCCCGTGCGCGCGCCCAGCCACCGCTT
CGCTCGCATCGGCGTGCTCTGCGCCCTGCTCCTGCTGGCGGTCTACGCCGTGGCGGCCCTGGCCCGCTTCGGCGGCGGGG
CGCAGAGCGCGGCCGAACAGCTCGCCTGGATCGCCGCCCCGCTGCTGGTCGCCATCGGCCTTGGCGTCCTGCTGCTGGTG
GAATCCCTGCGGGTCGAGCGGGCGCACGCCGCCTTCAGCGATTCCGAGCAGCGGTTCCGGATGGCCGTCGAGGCGGCCCG
CTGCGGCATCTGGGAATGGGACCTGGCGGCCGACAAGATCTTCATGTCCGAGGTGACGGCCGCCCTGTTCGGCTGGCGCG
GCGGGGTGGTGGACGGCCAGCAGGTGCTGGACCGCGTCTCGCCCGGCCATCGCGACGGTCTGCGCGAGGCGCTCGCCAAC
GCCGCGATCTACGGCGACTTCGACGTCTCGTTCCGGGTGCCCAGCCTGGCGGGCGGACGGCCGATCTGGATCGACGCCCG
CGGCCGCGGCTTCGGCGAGGCGCCCGAGGGGGGCTATGCGCGGATCATCGGCGTGGCGCTGGACGTCACCGAGGAGCGGC
TGGCCCAGGCCCGCGCCCAGCAGGCCGAGAGCCGCCTGCGGGACGCGATCGAGAGCGTCTCGGAGGCCTTCGTGCTGTGG
GACCGCCACGGGCGGCTCCTGATGTGCAACCGCAACTACCGCGACTACTTCAAGCTGGAGTCCGGCCTGCTCCTCGCCGG
GGTCGGCCGCGAACAGGTCGAGCGCGCCGCGCGCATGGCCGTGCGCCAGGAGTATCCCGCCCCTGGCGACCGCCGCGGCG
TGCGCGAGGCCGAGCTCGCCGACGGCCGCTGGGTGCAGATCTCGGAGCGGCCCACCGCCGAGGGCGGCCTTGTGGTCACC
GCCGCCGACATCACCGTGCTGAAGGCCCAGGAGGAGGCGCGCCGGCTGAAGGAGGAGGAACTGCGCCGGGCGGTGTTCAA
CCTCGAACGCAGCCAGGAGCAGCTCTCGGAGCTGGCCCGCAAGTACGAGGCCGAGAAGATCCGCGCCGAGGGCGCCAGCC
AGGCCAAGAGCGAGTTCCTGGCCAACATGAGCCACGAGCTGCGCACGCCGCTGAACGCCATCAACGGCTTTTCCGAGATC
ATGGTGGCCGAGATGTACGGCCCGCTGGGCGACGCCCGCTACCGCGACTACGCCCGCGACATCCTGAACTCGGGCCAGCA
CCTGCTCGCCCTGATCAACGACATCCTCGACATGTCCAAGATCGAGGCCGGCAAGATGAGCCTGCGCTTCGATCCCTGCT
CGCTGGAGGAGATCGCCGAGGACGCCCTGCGGCTGGTGCGCAACCGCGCCGAGAGCGCCGGCCTGACGCTGGTTCTGGAT
TTCGTCGAGCTGCCCGAGGTGGAGGCCGACTACCGGGCGGTGAAGCAGGTGCTGCTGAACCTGCTTTCCAACGCCATCAA
GTTCACGCCCCGCGGCGGCCGCATCACCCTGCGCGCCGAGCGCCGGGACGATCCGCTGGGCCAGCGGGTGCGGGTCAGCG
TCCAGGACACCGGCATCGGCATCGCGCCCGAGGACCTGGAGCGCCTGGCCCGGCCGTTCGAACAGGTCGAGAGCCAGCAT
GCCAAGACCCAGCAGGGGACGGGCCTGGGCCTTGCCCTCACCAAGGCCTTCGTCGAGCTGCACGGCGGCCTGCTGGACTT
GAAGAGCGCCCCCGGCCAGGGGACGACGGCGAGCTTCTCGCTACCGGTCCGGCAGAGCCGGGGGGCCGCCATGACGGCCG
CCAGGATCGGGGCCGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
TCCGCCCGAGCCACGGTTACGCCCCGGATACTCTTGGCGTAGTCTGCTGATTTGCTGATTTGCGCCGGCAGACCGGCGCA
GGCGTAAGGAGCAGCGGGCC

Downstream 100 bases:

>100_bases
GGCACGCGGCGCGGCCAGCGCCTTGCCGAAACGGATCCGGTCGGCCGCCGGCAGGGTTGCGGCGAACTCCACGAGCTGGC
GGTCGGCCAGCGCGCGGCCC

Product: sensor histidine kinase (non-motile and phage-resistance protein )

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MAKGGGRKAAGGARPALAPVRAPSHRFARIGVLCALLLLAVYAVAALARFGGGAQSAAEQLAWIAAPLLVAIGLGVLLLV
ESLRVERAHAAFSDSEQRFRMAVEAARCGIWEWDLAADKIFMSEVTAALFGWRGGVVDGQQVLDRVSPGHRDGLREALAN
AAIYGDFDVSFRVPSLAGGRPIWIDARGRGFGEAPEGGYARIIGVALDVTEERLAQARAQQAESRLRDAIESVSEAFVLW
DRHGRLLMCNRNYRDYFKLESGLLLAGVGREQVERAARMAVRQEYPAPGDRRGVREAELADGRWVQISERPTAEGGLVVT
AADITVLKAQEEARRLKEEELRRAVFNLERSQEQLSELARKYEAEKIRAEGASQAKSEFLANMSHELRTPLNAINGFSEI
MVAEMYGPLGDARYRDYARDILNSGQHLLALINDILDMSKIEAGKMSLRFDPCSLEEIAEDALRLVRNRAESAGLTLVLD
FVELPEVEADYRAVKQVLLNLLSNAIKFTPRGGRITLRAERRDDPLGQRVRVSVQDTGIGIAPEDLERLARPFEQVESQH
AKTQQGTGLGLALTKAFVELHGGLLDLKSAPGQGTTASFSLPVRQSRGAAMTAARIGAAAA

Sequences:

>Translated_621_residues
MAKGGGRKAAGGARPALAPVRAPSHRFARIGVLCALLLLAVYAVAALARFGGGAQSAAEQLAWIAAPLLVAIGLGVLLLV
ESLRVERAHAAFSDSEQRFRMAVEAARCGIWEWDLAADKIFMSEVTAALFGWRGGVVDGQQVLDRVSPGHRDGLREALAN
AAIYGDFDVSFRVPSLAGGRPIWIDARGRGFGEAPEGGYARIIGVALDVTEERLAQARAQQAESRLRDAIESVSEAFVLW
DRHGRLLMCNRNYRDYFKLESGLLLAGVGREQVERAARMAVRQEYPAPGDRRGVREAELADGRWVQISERPTAEGGLVVT
AADITVLKAQEEARRLKEEELRRAVFNLERSQEQLSELARKYEAEKIRAEGASQAKSEFLANMSHELRTPLNAINGFSEI
MVAEMYGPLGDARYRDYARDILNSGQHLLALINDILDMSKIEAGKMSLRFDPCSLEEIAEDALRLVRNRAESAGLTLVLD
FVELPEVEADYRAVKQVLLNLLSNAIKFTPRGGRITLRAERRDDPLGQRVRVSVQDTGIGIAPEDLERLARPFEQVESQH
AKTQQGTGLGLALTKAFVELHGGLLDLKSAPGQGTTASFSLPVRQSRGAAMTAARIGAAAA
>Mature_620_residues
AKGGGRKAAGGARPALAPVRAPSHRFARIGVLCALLLLAVYAVAALARFGGGAQSAAEQLAWIAAPLLVAIGLGVLLLVE
SLRVERAHAAFSDSEQRFRMAVEAARCGIWEWDLAADKIFMSEVTAALFGWRGGVVDGQQVLDRVSPGHRDGLREALANA
AIYGDFDVSFRVPSLAGGRPIWIDARGRGFGEAPEGGYARIIGVALDVTEERLAQARAQQAESRLRDAIESVSEAFVLWD
RHGRLLMCNRNYRDYFKLESGLLLAGVGREQVERAARMAVRQEYPAPGDRRGVREAELADGRWVQISERPTAEGGLVVTA
ADITVLKAQEEARRLKEEELRRAVFNLERSQEQLSELARKYEAEKIRAEGASQAKSEFLANMSHELRTPLNAINGFSEIM
VAEMYGPLGDARYRDYARDILNSGQHLLALINDILDMSKIEAGKMSLRFDPCSLEEIAEDALRLVRNRAESAGLTLVLDF
VELPEVEADYRAVKQVLLNLLSNAIKFTPRGGRITLRAERRDDPLGQRVRVSVQDTGIGIAPEDLERLARPFEQVESQHA
KTQQGTGLGLALTKAFVELHGGLLDLKSAPGQGTTASFSLPVRQSRGAAMTAARIGAAAA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=36.0902255639098, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=37.2759856630824, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788713, Length=273, Percent_Identity=36.2637362637363, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=36.9811320754717, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=34.8936170212766, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786600, Length=384, Percent_Identity=27.0833333333333, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=27.6264591439689, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=28.125, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786912, Length=296, Percent_Identity=29.0540540540541, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790436, Length=260, Percent_Identity=31.5384615384615, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=272, Percent_Identity=28.3088235294118, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790861, Length=255, Percent_Identity=30.9803921568627, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=25.2173913043478, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=239, Percent_Identity=26.7782426778243, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=286, Percent_Identity=26.5734265734266, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=207, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=27.6119402985075, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67586; Mature: 67455

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGGGRKAAGGARPALAPVRAPSHRFARIGVLCALLLLAVYAVAALARFGGGAQSAAEQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LAWIAAPLLVAIGLGVLLLVESLRVERAHAAFSDSEQRFRMAVEAARCGIWEWDLAADKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEHHHHHHH
FMSEVTAALFGWRGGVVDGQQVLDRVSPGHRDGLREALANAAIYGDFDVSFRVPSLAGGR
HHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCEEEECCCCEEECCCCCCCC
PIWIDARGRGFGEAPEGGYARIIGVALDVTEERLAQARAQQAESRLRDAIESVSEAFVLW
EEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
DRHGRLLMCNRNYRDYFKLESGLLLAGVGREQVERAARMAVRQEYPAPGDRRGVREAELA
ECCCCEEEECCCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC
DGRWVQISERPTAEGGLVVTAADITVLKAQEEARRLKEEELRRAVFNLERSQEQLSELAR
CCCEEEECCCCCCCCCEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYEAEKIRAEGASQAKSEFLANMSHELRTPLNAINGFSEIMVAEMYGPLGDARYRDYARD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
ILNSGQHLLALINDILDMSKIEAGKMSLRFDPCSLEEIAEDALRLVRNRAESAGLTLVLD
HHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEE
FVELPEVEADYRAVKQVLLNLLSNAIKFTPRGGRITLRAERRDDPLGQRVRVSVQDTGIG
HHHCCCCCHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCC
IAPEDLERLARPFEQVESQHAKTQQGTGLGLALTKAFVELHGGLLDLKSAPGQGTTASFS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCEEEE
LPVRQSRGAAMTAARIGAAAA
CCCHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
AKGGGRKAAGGARPALAPVRAPSHRFARIGVLCALLLLAVYAVAALARFGGGAQSAAEQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LAWIAAPLLVAIGLGVLLLVESLRVERAHAAFSDSEQRFRMAVEAARCGIWEWDLAADKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEHHHHHHH
FMSEVTAALFGWRGGVVDGQQVLDRVSPGHRDGLREALANAAIYGDFDVSFRVPSLAGGR
HHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCEEEECCCCEEECCCCCCCC
PIWIDARGRGFGEAPEGGYARIIGVALDVTEERLAQARAQQAESRLRDAIESVSEAFVLW
EEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
DRHGRLLMCNRNYRDYFKLESGLLLAGVGREQVERAARMAVRQEYPAPGDRRGVREAELA
ECCCCEEEECCCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC
DGRWVQISERPTAEGGLVVTAADITVLKAQEEARRLKEEELRRAVFNLERSQEQLSELAR
CCCEEEECCCCCCCCCEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYEAEKIRAEGASQAKSEFLANMSHELRTPLNAINGFSEIMVAEMYGPLGDARYRDYARD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
ILNSGQHLLALINDILDMSKIEAGKMSLRFDPCSLEEIAEDALRLVRNRAESAGLTLVLD
HHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEE
FVELPEVEADYRAVKQVLLNLLSNAIKFTPRGGRITLRAERRDDPLGQRVRVSVQDTGIG
HHHCCCCCHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCC
IAPEDLERLARPFEQVESQHAKTQQGTGLGLALTKAFVELHGGLLDLKSAPGQGTTASFS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCEEEE
LPVRQSRGAAMTAARIGAAAA
CCCHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]