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The map label for this gene is cofC

Identifier: 197105998

GI number: 197105998

Start: 2913154

End: 2913810

Strand: Reverse

Name: cofC

Synonym: PHZ_c2537

Alternate gene names: 197105998

Gene position: 2913810-2913154 (Counterclockwise)

Preceding gene: 197105999

Following gene: 197105997

Centisome position: 72.91

GC content: 76.56

Gene sequence:

>657_bases
GTGGCTGAGGCGATCCTCGCGGTCCGGGGCGGCCTGGGGGCCAAGTCGCGGTTGGCGGCGGTCTTCAGCGACGCCGAGCG
CGCGGCGCTCGTCGAGGCCATGCTGCTCGACATGCTCGACGCGCTTGCCGGGGCCGGGGCCGGGGCCGTCCGCCGCGTCT
GGGTGGTCACGCCCACCGAGAGGTTGGAGCGGCTGGCGGCGGCCGCCGGCGCGCGGGTGATCCGCGAGCCGCGGCCTGCC
GGCCTCAACGCTGCGTTCCGCTGCGGTCTGGCGGCGGCGGCCGAGGAGGCGCCCTACGCGGACATCGTGCTTCTTCCGGG
CGATCTGCCGACATTGCGGGCGCAGGACGTCGACGCCGCGCTGCTGCTGCTGCGAACGCACGACCTGGTGCTCGCGCTCG
CTTCCCGTGACGGGGGGACGGGCCTGCTGGCCGTCCGCGCAGGGGTCCCCTTCACGCCCCAGTTCGGCGCGCAGAGCTGC
GCGCGCCACCGGCGGCAGGCCCGCGCGCGGGGGCTGTCCTGCGCGCTGGTGGAGGCCGGGTCGCTGGCCCTCGACCTCGA
TCGGCCCGAGGACGCGGTGGAGGTGGCGCGCGGGCCCTGCGGCCGGCGGACGGCCGAAGTCCTGAGCGATCTCAAGAGCC
GCTGGAGAGCCCAATGA

Upstream 100 bases:

>100_bases
GTGGGGATGCGCGCGCGGCTCGCCCCCTCGGTGATGCGGAGCGACGTCGATCGTATCGAGCTCGCCCGGGCCACGCTCGC
CTTCGCCGAGGAGCTGCGTC

Downstream 100 bases:

>100_bases
AGCAAGCGGACCTGCGGCGGCGGCTGATGCGGTCGCCGATCGAGGCGCTGACAGCGGAGAGCGGGGCCCGGCGGGACGCC
GCCTTCGGCAGGACGCTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MAEAILAVRGGLGAKSRLAAVFSDAERAALVEAMLLDMLDALAGAGAGAVRRVWVVTPTERLERLAAAAGARVIREPRPA
GLNAAFRCGLAAAAEEAPYADIVLLPGDLPTLRAQDVDAALLLLRTHDLVLALASRDGGTGLLAVRAGVPFTPQFGAQSC
ARHRRQARARGLSCALVEAGSLALDLDRPEDAVEVARGPCGRRTAEVLSDLKSRWRAQ

Sequences:

>Translated_218_residues
MAEAILAVRGGLGAKSRLAAVFSDAERAALVEAMLLDMLDALAGAGAGAVRRVWVVTPTERLERLAAAAGARVIREPRPA
GLNAAFRCGLAAAAEEAPYADIVLLPGDLPTLRAQDVDAALLLLRTHDLVLALASRDGGTGLLAVRAGVPFTPQFGAQSC
ARHRRQARARGLSCALVEAGSLALDLDRPEDAVEVARGPCGRRTAEVLSDLKSRWRAQ
>Mature_217_residues
AEAILAVRGGLGAKSRLAAVFSDAERAALVEAMLLDMLDALAGAGAGAVRRVWVVTPTERLERLAAAAGARVIREPRPAG
LNAAFRCGLAAAAEEAPYADIVLLPGDLPTLRAQDVDAALLLLRTHDLVLALASRDGGTGLLAVRAGVPFTPQFGAQSCA
RHRRQARARGLSCALVEAGSLALDLDRPEDAVEVARGPCGRRTAEVLSDLKSRWRAQ

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFC_PHEZH (B4RGP0)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131375.1
- ProteinModelPortal:   B4RGP0
- GeneID:   6792058
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2537
- HOGENOM:   HBG699055
- HAMAP:   MF_02114
- InterPro:   IPR002835
- TIGRFAMs:   TIGR03552

Pfam domain/function: PF01983 DUF121

EC number: =2.7.7.68

Molecular weight: Translated: 22787; Mature: 22655

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAILAVRGGLGAKSRLAAVFSDAERAALVEAMLLDMLDALAGAGAGAVRRVWVVTPTE
CCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEECCHH
RLERLAAAAGARVIREPRPAGLNAAFRCGLAAAAEEAPYADIVLLPGDLPTLRAQDVDAA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHH
LLLLRTHDLVLALASRDGGTGLLAVRAGVPFTPQFGAQSCARHRRQARARGLSCALVEAG
HHHHHHHHHEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
SLALDLDRPEDAVEVARGPCGRRTAEVLSDLKSRWRAQ
CEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEAILAVRGGLGAKSRLAAVFSDAERAALVEAMLLDMLDALAGAGAGAVRRVWVVTPTE
CCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEECCHH
RLERLAAAAGARVIREPRPAGLNAAFRCGLAAAAEEAPYADIVLLPGDLPTLRAQDVDAA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHH
LLLLRTHDLVLALASRDGGTGLLAVRAGVPFTPQFGAQSCARHRRQARARGLSCALVEAG
HHHHHHHHHEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECC
SLALDLDRPEDAVEVARGPCGRRTAEVLSDLKSRWRAQ
CEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA